Aliases for VARS Gene
External Ids for VARS Gene
Previous HGNC Symbols for VARS Gene
Previous GeneCards Identifiers for VARS Gene
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
GeneCards Summary for VARS Gene
VARS (Valyl-TRNA Synthetase) is a Protein Coding gene. Diseases associated with VARS include scotoma. Among its related pathways are Gene Expression and tRNA Aminoacylation. GO annotations related to this gene include aminoacyl-tRNA editing activity and valine-tRNA ligase activity. An important paralog of this gene is VARS2.