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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VAMP7 Gene

protein-coding   GIFtS: 62
GCID: GC0XP155110

vesicle-associated membrane protein 7

(Previous name: synaptobrevin-like 1 )
(Previous symbol: SYBL1)
 Explore 12 diseases affiliated with
VAMP7 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for VAMP7    

Aliases
for VAMP7 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Vesicle-Associated Membrane Protein 71 2     Synaptobrevin-Like Protein 12 3
SYBL11 2 3 5     Tetanus-Insensitive VAMP2 3
VAMP-71 2 3     TIVAMP2 5
TI-VAMP1 2     Tetanus Neurotoxin-Insensitive VAMP2
Synaptobrevin-Like 11 2     Ti-VAMP3

External Ids:    HGNC: 114861   Entrez Gene: 68452   Ensembl: ENSG000001243337   OMIM: 3000535   UniProtKB: P518093   
ORGUL members:         
NONCODE:n409350    

Export aliases for VAMP7 gene to outside databases

Previous GC identifers: GC0XP154764 GC0XP143593


Summaries
for VAMP7 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for VAMP7:
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment
protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the
fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript
variants.(provided by RefSeq, Jun 2010)

UniProtKB/Swiss-Prot: VAMP7_HUMAN, P51809
Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of
proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and
homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of
chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil
and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late
endocytic vesicles during phagosome formation

Gene Wiki entry for VAMP7 (SYBL1)


Genomic Views
for VAMP7 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_000024.9  NC_018934.1  NT_167198.1  NT_167206.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VAMP7 gene promoter:
         AREB6   C/EBPbeta   Nkx2-5   Meis-1   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VAMP7 promoter sequence
   Search SABiosciences Chromatin IP Primers for VAMP7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAMP7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28 and Yq12   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28 and Yq12

VAMP7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VAMP7 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP155110:  view genomic region     (about GC identifiers)

Start:
 155,110,943 bp from pter      End:
 155,173,433 bp from pter
Size:
 62,491 bases      Orientation:
 plus strand

1 alternative location:
ChrY+ 59,213,949-59,276,439     

Proteins
for VAMP7 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: VAMP7_HUMAN, P51809 (See protein sequence)
Recommended Name: Vesicle-associated membrane protein 7  
Size: 220 amino acids; 24935 Da
Subunit: Component of the SNARE complex composed of STX4, SNAP23 and VAMP7 that binds SYT7 during lysosomal exocytosis.
Component of the SNARE complex composed of STX7, STX8, VAMP7 and VTI1B that is required for heterotypic fusion of late
endosomes with lysosomes in liver cells (By similarity)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein (By
similarity). Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein (By similarity). Late
endosome membrane; Single-pass type IV membrane protein (By similarity). Lysosome membrane; Single-pass type IV
membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity). Cytoplasmic
vesicle, phagosome membrane; Single-pass type IV membrane protein (By similarity). Cell junction, synapse, synaptosome
(By similarity). Note=In immature neurons expression is localized in vesicular structures in axons and dendrites while
in mature neurons it is localized to the somatodendritic region. Colocalizes with LAMP1 in kidney cells. Localization
to the endoplasmic reticulum membrane was observed in the intestine but not in liver or kidney (By similarity)
Miscellaneous: The gene encoding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Y
chromosomes
Miscellaneous: Loss-of-function mutant (antisense inhibition) displays impaired granzyme B release and target cell
killing by natural killer cells
Sequence caution: Sequence=BI547528; Type=Miscellaneous discrepancy; Note=Sequence of unknown origin in the C-terminal
part;
2 PDB 3D structures from and Proteopedia for VAMP7:
2DMW (3D)        2VX8 (3D)    
Secondary accessions: Q53GY7 Q7Z409 Q9H4A7
Alternative splicing: 3 isoforms:  P51809-1   P51809-2   P51809-3   

Explore the universe of human proteins at neXtProt for VAMP7: NX_P51809

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P51809

    • VAMP7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001138621.1  NP_001172112.1  NP_005629.1  

    ENSEMBL proteins: 
     ENSP00000286448   ENSP00000430039   ENSP00000262640   ENSP00000427822  
    Reactome Protein details: P51809
    Human Recombinant Protein Products: 
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    ProSpec Recombinant Protein for VAMP7
    Uscn Proteins for VAMP7

    Gene Ontology (GO): 5/17 cellular component terms (GO ID links to tree view) (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005765lysosomal membrane TAS--
    GO:0005789endoplasmic reticulum membrane ISS16495485
    GO:0005794Golgi apparatus IDA--
    GO:0005886plasma membrane TAS--


    VAMP7 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for VAMP7 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    VAMP7 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR010908 Longin_dom
     IPR001388 Synaptobrevin
     IPR011012 Longin-like_dom

    Graphical View of Domain Structure for InterPro Entry P51809

    ProtoNet protein and cluster: P51809

    1 Blocks protein family: IPB001388 Synaptobrevin

    UniProtKB/Swiss-Prot: VAMP7_HUMAN, P51809
    Similarity: Belongs to the synaptobrevin family
    Similarity: Contains 1 longin domain
    Similarity: Contains 1 v-SNARE coiled-coil homology domain


    Function
    for VAMP7 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: VAMP7_HUMAN, P51809
    Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of
    proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and
    homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of
    chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil
    and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late
    endocytic vesicles during phagosome formation

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: VAMP7 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18775314
    GO:0019905syntaxin binding IEA--


    VAMP7 for ontologies           About GeneDecksing



    Pathways & Interactions
    for VAMP7 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin derived vesicle budding
    		Clathrin derived vesicle budding1.00
    		Golgi Associated Vesicle Biogenesis0.89
    		trans-Golgi Network Vesicle Budding1.00
    		Lysosome Vesicle Biogenesis0.39
    2Membrane Trafficking
    		Membrane Trafficking1.00
    3Clathrin-dependent protein traffic
    		Transport_Clathrin-coated vesicle cycle0.66
    4Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    		SNARE interactions in vesicular transport0.40

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for VAMP7
        Transport Clathrin-coated vesicle cycle

    5        Reactome Pathways for VAMP7
        Membrane Trafficking
    Clathrin derived vesicle budding
    Golgi Associated Vesicle Biogenesis
    trans-Golgi Network Vesicle Budding
    Lysosome Vesicle Biogenesis


    1         Kegg Pathway  (Kegg details for VAMP7):
        SNARE interactions in vesicular transport


    VAMP7 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VAMP7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/59 Interacting proteins for VAMP7 (P518091, 2, 3 ENSP000002864484) via UniProtKB, MINT, STRING, and/or I2D (see all 59)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGFG1P525941, 3EBI-1052205,EBI-996560 I2D: score=1 
    STX7O154002, 3, ENSP000003569184MINT-7255549 I2D: score=2 STRING: ENSP00000356918
    ANKRD27Q96NW42, 3, ENSP000003042924MINT-7293235 I2D: score=1 STRING: ENSP00000304292
    AP3D1O146173, ENSP000003440554I2D: score=6 STRING: ENSP00000344055
    DNAJC13O751653, ENSP000002608184I2D: score=2 STRING: ENSP00000260818
    About this table

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006888ER to Golgi vesicle-mediated transport ISS16495485
    GO:0006892post-Golgi vesicle-mediated transport TAS--
    GO:0006906vesicle fusion IDA10888671
    GO:0006911phagocytosis, engulfment ISS15133481
    GO:0008333endosome to lysosome transport IDA10888671


    VAMP7 for ontologies           About GeneDecksing



    Drugs & Compounds
    for VAMP7 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    VAMP7 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for VAMP7

    1 HMDB Compound for VAMP7    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    1 Novoseek chemical compound relationship for VAMP7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sulfamethoxypyridazine 84.5 7 15544955 (2), 18775314 (1)

    Search CenterWatch for drugs/clinical trials and news about VAMP7 

    Transcripts
    for VAMP7 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for VAMP7 gene (3 alternative transcripts): 
    NM_001145149.2  NM_001185183.1  NM_005638.5  

    Unigene Cluster for VAMP7:

    Vesicle-associated membrane protein 7
    Hs.24167  [show with all ESTs]
    Unigene Representative Sequence: BC056141
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000286448(uc011naa.2 uc004fnr.3 uc011nab.2 uc004fnt.3 uc004fns.3 uc011nac.2)
    ENST00000479687 ENST00000488344 ENST00000463317 ENST00000262640 ENST00000460621


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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate VAMP7 (see all 40):
    hsa-miR-2052 hsa-miR-26a-2* hsa-miR-4272 hsa-miR-15a hsa-miR-29a hsa-miR-218 hsa-miR-124 hsa-miR-9
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    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AJ295938.1 AJ549301.2 AK222794.1 AK293525.1 AK295605.1 AK312658.1 BC056141.1 NR_033714.1 
    NR_033715.1 X92396.1 

    21 DOTS entries:

    DT.100650163  DT.416737  DT.97855551  DT.91661651  DT.121314006  DT.100725352  DT.120654130  DT.121314010 
    DT.121314011  DT.121314013  DT.92432660  DT.95123613  DT.100805541  DT.120654148  DT.121314001  DT.95112539 
    DT.97855552  DT.100641005  DT.100650162  DT.120654177  DT.121314000 

    24/231 AceView cDNA sequences (see all 231):

    BM993490 AA622708 BM783745 AI476446 AW474256 F01794 CB270110 AA838476 
    F05523 AI522015 AA039917 BM511886 BQ431803 AI202446 BM904257 CK905692 
    BG571403 AJ549301 BE893202 AA565995 AA854952 AI146794 C00912 AI888285 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for VAMP7    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                                                            
    SP2:                                      -                     


    ECgene alternative splicing isoforms for VAMP7

    Expression
    for VAMP7 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VAMP7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTCATTTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See VAMP7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VAMP7

    SOURCE GeneReport for Unigene cluster: Hs.24167

    UniProtKB/Swiss-Prot: VAMP7_HUMAN, P51809
    Tissue specificity: Detected in all tissues tested

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    In Situ
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    Orthologs
    for VAMP7 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for VAMP7 gene from 7/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves VAMP71 vesicle-associated membrane protein 7 84.7(n)
    94.09(a)    		   422297  NM_001031121.1  NP_001026292.1 
    lizard
    (Anolis carolinensis)    		 Reptilia VAMP76
    		 --
    		 66(a)
    		 1 ↔ 1
    		 GL343202.1(1804475-1809234)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.95162 Xenopus laevis transcribed sequence with strong similarity more 79.86(n)    BU916994.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc565062 similar to synaptobrevin-like 1 72.63(n)   393236  BC049034.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG15991 CG1599 54.59(n)
    52.29(a)    		   36015  NM_136680.3  NP_610524.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons VAMP7141 vesicle-associated membrane protein 714 51.61(n)
    41.94(a)    		   832297  NM_122141.4  NP_197628.1 
    rice
    (Oryza sativa)    		 Liliopsida Os10g01540001 hypothetical protein 48.23(n)
    41.01(a)    		   4348130  NM_001070719.1  NP_001064184.1 


    ENSEMBL Gene Tree for VAMP7 (if available)
    TreeFam Gene Tree for VAMP7 (if available) 

    Paralogs
    for VAMP7 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for VAMP7 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for VAMP7
         1 CNV: 0825
         2 Indels: 33496 33491
    Human Gene Mutation Database (HGMD): VAMP7

    Locus Specific Mutation Databases (LSDB): VAMP7
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VAMP7
    DNA2.0 Custom Variant and Variant Library Synthesis for VAMP7

    Disorders / Diseases
    for VAMP7 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    VAMP7 for disorders           About GeneDecksing

    OMIM gene information: 300053    OMIM disorders: --

    12 diseases for VAMP7:    About MalaCards
    tetanus    bipolar affective disorder    x inactivation    klinefelter's syndrome
    chronic myeloid leukemia    rett syndrome    myeloid leukemia    bipolar disorder
    leukemia    melanoma    malaria    neuronitis

    2 Novoseek disease relationships for VAMP7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    icf syndrome 82.4 1 12444103 (1)
    tetanus 73.2 16 10811829 (2), 17335083 (1), 19576189 (1), 9614185 (1) (see all 9)

    Human Genome Epidemiology (HuGE) Navigator: VAMP7 (1 document)

    Export disorders for VAMP7 gene to outside databases

    Publications
    for VAMP7 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VAMP7 gene, integrated from 9 sources (see all 87):
    (articles sorted by number of sources associating them with VAMP7)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation. (PubMed id 8640232)1, 2, 3 D'Esposito M.... D'Urso M. (1996)
    2. Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. (PubMed id 18042464)1, 2 Marcet-Palacios M.... Moqbel R. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A dual mechansim controlling the localization and function of exocytic v-SNARE. (PubMed id 12853575)1, 2 Martinez-Arca S.... Galli T. (2003)
    5. Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain. (PubMed id 11440841)1, 3 Filippini F....D'Esposito M. (2001)
    6. Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. (PubMed id 10888671)1, 2 Ward D.M.... Kaplan J. (2000)
    7. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region. (PubMed id 10655549)1, 2 Ciccodicola A.... D'Urso M. (2000)
    8. Human synaptobrevin-like 1 gene basal transcription is regulated through the interaction of selenocysteine tRNA gene transcription activating factor-zinc finger 143 factors with evolutionary conserved cis-elements. (PubMed id 14672948)1, 9 Di Leva F....Franze A. (2004)
    9. VAMP-7 mediates vesicular transport from endosomes to lysosomes. (PubMed id 10459012)1, 9 Advani R.J....Scheller R.H. (1999)
    10. Role of HRB in clathrin-dependent endocytosis. (PubMed id 18819912)1, 9 Chaineau M....Galli T. (2008)

    External Searches for VAMP7 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing VAMP7 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6845 HGNC: 11486 AceView: SYBL1.1 Ensembl:ENSG00000124333 euGenes: HUgn6845
    ECgene: VAMP7 Kegg: 6845 H-InvDB: VAMP7

    Other Databases showing VAMP7 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing VAMP7 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VAMP7 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for VAMP7 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for VAMP7 gene:
    Search GeneIP for patents involving VAMP7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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