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VAMP5 Gene

protein-coding   GIFtS: 58
GCID: GC02P085811

Vesicle-Associated Membrane Protein 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Vesicle-Associated Membrane Protein 51 2
myobrevin1 2
VAMP-52 3
Myobrevin3

External Ids:    HGNC: 126461   Entrez Gene: 107912   Ensembl: ENSG000001688997   OMIM: 6070295   UniProtKB: O951833   

Export aliases for VAMP5 gene to outside databases

Previous GC identifers: GC02P085706 GC02P086105 GC02P085786 GC02P085723 GC02P085665 GC02P085708


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for VAMP5 Gene:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a
protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member
of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP
family member may participate in vesicle trafficking events that are associated with myogenesis. (provided by
RefSeq, Jul 2008)

GeneCards Summary for VAMP5 Gene:
VAMP5 (vesicle-associated membrane protein 5) is a protein-coding gene. Diseases associated with VAMP5 include primary open angle glaucoma, and open-angle glaucoma.

UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183
Function: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion
and/or GLUT4 trafficking




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the VAMP5 gene promoter:
         c-Fos   AP-1   JunB   Fra-1   FosB   JunD   FOXC1   E2F-1   Msx-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVAMP5 promoter sequence
   Search Chromatin IP Primers for VAMP5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat VAMP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11.2   Ensembl cytogenetic band:  2p11.2   HGNC cytogenetic band: 2p11.2

VAMP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VAMP5 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P085811:  view genomic region     (about GC identifiers)

Start:
85,811,531 bp from pter      End:
85,820,535 bp from pter
Size:
9,005 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183 (See protein sequence)
Recommended Name: Vesicle-associated membrane protein 5  
Size: 116 amino acids; 12805 Da
Secondary accessions: Q9P0T2

Explore the universe of human proteins at neXtProt for VAMP5: NX_O95183

Explore proteomics data for VAMP5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys26, Lys33
  • Modification sites at PhosphoSitePlus

  • See VAMP5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006625.1  
    ENSEMBL proteins: 
     ENSP00000305647  

    VAMP5 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    VAMP: Vesicle-associated membrane proteins

    2 InterPro protein domains:
     IPR016444 Synaptobrevin/VAMP_met/fun
     IPR001388 Synaptobrevin

    Graphical View of Domain Structure for InterPro Entry O95183

    ProtoNet protein and cluster: O95183

    1 Blocks protein domain: IPB001388 Synaptobrevin

    UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183
    Similarity: Belongs to the synaptobrevin family
    Similarity: Contains 1 v-SNARE coiled-coil homology domain


    VAMP5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VAMP5_HUMAN, O95183
    Function: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion
    and/or GLUT4 trafficking
    Induction: During myogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000149SNARE binding IBA--
    GO:0005484SNAP receptor activity IBA--
         
    VAMP5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for VAMP5:
     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for VAMP5
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for VAMP5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for VAMP5

    miRNA
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    miRTarBase miRNAs that target VAMP5:
    hsa-mir-335-5p (MIRT018608)

    Block miRNA regulation of human, mouse, rat VAMP5 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate VAMP5:
    hsa-miR-516b hsa-miR-608 hsa-miR-3670
    SwitchGear 3'UTR luciferase reporter plasmidVAMP5 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat VAMP5

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: VAMP5 (NM_006634)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAMP5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    VAMP5_HUMAN, O95183: Cell membrane; Single-pass type IV membrane protein (Probable). Endomembrane system;
    Single-pass type IV membrane protein (Probable). Golgi apparatus, trans-Golgi network membrane; Single-pass type
    IV membrane protein (Probable). Note=Associated with the plasma membrane as well as intracellular perinuclear and
    peripheral vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi
    apparatus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    golgi apparatus3
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IEA--
    GO:0005886plasma membrane TAS9725904
    GO:0005887integral component of plasma membrane IEA--
    GO:0008021synaptic vesicle IBA--

    VAMP5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for VAMP5 About    
    See pathways by source

    SuperPathContained pathways About
    1Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics0.44
    SNARE interactions in vesicular transport0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 PharmGKB Pathway for VAMP5
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    1 Kegg Pathway  (Kegg details for VAMP5):
        SNARE interactions in vesicular transport


    VAMP5 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for VAMP5
    Interactions:

        Search GeneGlobe Interaction Network for VAMP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for VAMP5 (ENSP000003056474) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GOSR2ENSP000002255674STRING: ENSP00000225567
    SCFD1ENSP000003907834STRING: ENSP00000390783
    STX5ENSP000002941794STRING: ENSP00000294179
    YKT6ENSP000002233694STRING: ENSP00000223369
    PTRH1ENSP000004186614STRING: ENSP00000418661
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006887exocytosis IBA--
    GO:0006906vesicle fusion IBA--
    GO:0007269neurotransmitter secretion IBA--
    GO:0007517muscle organ development TAS9725904
    GO:0007519skeletal muscle tissue development IEA--

    VAMP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for VAMP5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for VAMP5 gene: 
    NM_006634.2  

    Unigene Cluster for VAMP5:

    Vesicle-associated membrane protein 5
    Hs.534373  [show with all ESTs]
    Unigene Representative Sequence: BE618868
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306384(uc002spu.1) ENST00000462451
    miRNA
    Products:
         
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    3 qRT-PCR Assays for microRNAs that regulate VAMP5:
    hsa-miR-516b hsa-miR-608 hsa-miR-3670
    SwitchGear 3'UTR luciferase reporter plasmidVAMP5 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for VAMP5
    Predesigned siRNA for gene silencing in human, mouse, rat VAMP5
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    GenScript: all cDNA clones in your preferred vector: VAMP5 (NM_006634)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for VAMP5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VAMP5
    Primer
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    OriGene qPCR primer pairs and template standards for VAMP5
    OriGene qSTAR qPCR primer pairs in human, mouse for VAMP5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat VAMP5
      QuantiTect SYBR Green Assays in human, mouse, rat VAMP5
      QuantiFast Probe-based Assays in human, mouse, rat VAMP5

    Additional mRNA sequence: 

    AF054825.1 AF077197.1 AF151025.1 AK292660.1 BC017891.1 CR542215.1 

    11 DOTS entries:

    DT.314218  DT.100748293  DT.100881723  DT.121152203  DT.121152226  DT.100881736  DT.121627652  DT.91772578 
    DT.100881733  DT.100881747  DT.92431991 

    Selected AceView cDNA sequences (see all 316):

    AI419209 AA361428 BQ675243 CB108371 BX113655 NM_006634 BC017891 AI418592 
    AA176219 N90862 AA305331 CB156929 BM761526 AA309787 BQ227618 AA836089 
    AA634593 AI568721 BM707971 BM702226 CR594380 AA371270 BX092149 W80846 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for VAMP5    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c
    SP1:              -                           
    SP2:              -                           
    SP3:                                          


    ECgene alternative splicing isoforms for VAMP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    VAMP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGGCCAGC
    VAMP5 Expression
    About this image


    VAMP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Kidney (Urinary System)
             S-shaped Body
     
     Heart (Cardiovascular System)
             Primitive Heart Tube Cells Primitive Heart Tube
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Lung (Respiratory System)
    VAMP5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    VAMP5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.534373
        Custom PCR Arrays for VAMP5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAMP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for VAMP5 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vamp51 , 5 vesicle-associated membrane protein 51, 5 79.33(n)1
    74(a)1
      6 (32.27 cM)5
    536201  NM_016872.41  NP_058568.11 
     723680495 
    zebrafish
    (Danio rerio)
    Actinopterygii vamp56
    vesicle-associated membrane protein 5
    33(a)
    1 ↔ 1
    5(29941799-29952019) ENSDARG00000068262


    ENSEMBL Gene Tree for VAMP5 (if available)
    TreeFam Gene Tree for VAMP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for VAMP5 gene
    6 SIMAP similar genes for VAMP5 using alignment to 2 protein entries:     VAMP5_HUMAN (see all proteins):
    VAMP4    VAMP8    VAMP2    VAMP3    VAMP1    SYBL1

    VAMP5 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for VAMP5
    PGOHUM00000237420


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for VAMP5 (see all 210)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75939691,2
    C,F,A,H--85809670(+) AAGGCC/TTCTGG 1 -- us2k119Minor allele frequency- T:0.33NS EA NA WA CSA 2341
    rs76080741,2
    C,F,A,H--85809703(+) AAGCAT/GCTCTC 1 -- us2k18Minor allele frequency- G:0.37NA WA CSA EA 371
    rs15623231,2
    C,F,A,H--85809711(-) ATGCCA/GAGGAG 1 -- us2k113Minor allele frequency- G:0.45MN NA WA CSA EA 559
    rs1126859561,2
    F--85809721(+) TCCCAC/TGGCTG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs577626991,2
    F--85809867(+) CAGTCC/TGCCTT 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs791395171,2
    C,F--85809872(+) CGCCTT/CGGTTT 1 -- us2k11Minor allele frequency- C:0.06EA 120
    rs23666391,2
    C,F,A,H--85809955(+) CAGGAA/GGAAGG 1 -- us2k1 trp39Minor allele frequency- G:0.45NA WA CSA EA 369
    rs15611981,2
    C,F,O,A,H--85809989(-) AATCTA/GGTCCC 1 -- us2k124Minor allele frequency- G:0.48MN NS EA NA WA CSA 2531
    rs1384191441,2
    C--85810122(+) CAGACA/TGGAGT 1 -- us2k10--------
    rs1915594541,2
    --85810366(+) CACTGC/TGCCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for VAMP5 (85811531 - 85820535 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for VAMP5: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing VAMP5
    DNA2.0 Custom Variant and Variant Library Synthesis for VAMP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607029    OMIM disorders: --

    7 diseases for VAMP5:    
    About MalaCards
    primary open angle glaucoma    open-angle glaucoma    glaucoma    prostate cancer
    prostatitis    neuronitis    endotheliitis


    VAMP5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): VAMP5
    Human Genome Epidemiology (HuGE) Navigator: VAMP5 (12 documents)

    Export disorders for VAMP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for VAMP5 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with VAMP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. (PubMed id 9725904)1, 2, 3, 9 Zeng Q.... Hong W. (Mol. Biol. Cell 1998)
    2. VAMP5 and VAMP8 are most likely not involved in primary open-angle glaucoma. (PubMed id 16110299)1, 4 Brinkman J.F....Bergen A.A. (Mol. Vis. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. (PubMed id 21743467)1 Kote-Jarai Z....TybjA ( 2011)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    9. Characterization of immunoisolated human gastric parietal cells tubulovesicles: identification of regulators of apical recycling. (PubMed id 17255364)1 Lapierre L.A....Goldenring J.R. (Am. J. Physiol. Gastrointest. Liver Physiol. 2007)
    10. The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network. (PubMed id 12682051)1 Zeng Q....Hong W. (J. Biol. Chem. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10791 HGNC: 12646 AceView: VAMP8andVAMP5 Ensembl:ENSG00000168899 euGenes: HUgn10791
    ECgene: VAMP5 Kegg: 10791 H-InvDB: VAMP5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for VAMP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for VAMP5 gene:
    Search GeneIP for patents involving VAMP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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