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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

VAMP5 Gene

protein-coding GIFtS: 55
GCID: GC02P085811

vesicle-associated membrane protein 5

Explore 5 diseases affiliated with
VAMP5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Vesicle-Associated Membrane Protein 5¹ ²
VAMP-5² ³
Myobrevin³
Myobrevin³

External Ids:	HGNC: 12646¹	Entrez Gene: 10791²	Ensembl: ENSG00000168899⁷	OMIM: 607029⁵	UniProtKB: O95183³

Export aliases for VAMP5 gene to outside databases

Previous GC identifers: GC02P085706 GC02P086105 GC02P085786 GC02P085723 GC02P085665 GC02P085708

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VAMP5:

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein

complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the

vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may

participate in vesicle trafficking events that are associated with myogenesis. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183

Function: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or

GLUT4 trafficking

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the VAMP5 gene promoter:
c-Fos AP-1 JunB Fra-1 FosB JunD FOXC1 E2F-1 Msx-1 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: VAMP5 promoter sequence

Search SABiosciences Chromatin IP Primers for VAMP5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAMP5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11.2 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p11.2

VAMP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VAMP5 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P085811: view genomic region (about GC identifiers)

Start:	85,811,531 bp from pter	End:	85,820,535 bp from pter
Size:	9,005 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183 (See protein sequence)

Recommended Name: Vesicle-associated membrane protein 5

Size: 116 amino acids; 12805 Da

Subcellular location: Cell membrane; Single-pass type IV membrane protein (Probable). Endomembrane system; Single-pass

type IV membrane protein (Probable). Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane

protein (Probable). Note=Associated with the plasma membrane as well as intracellular perinuclear and peripheral

vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi apparatus (By

similarity)

Secondary accessions: Q9P0T2

Explore the universe of human proteins at neXtProt for VAMP5: NX_O95183

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O95183

VAMP5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_006625.1

ENSEMBL proteins:

ENSP00000305647

Human Recombinant Protein Products:

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	ProSpec Recombinant Protein for VAMP5
	Uscn Proteins for VAMP5

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005794	Golgi apparatus	IEA	--
GO:0005802	trans-Golgi network	IEA	--
GO:0005886	plasma membrane	TAS	9725904
GO:0005887	integral to plasma membrane	IEA	--
GO:0012505	endomembrane system	IEA	--

VAMP5 for ontologies About GeneDecksing

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	Search for Antibodies for VAMP5 at Abcam
	Uscn Antibodies for VAMP5
	ThermoFisher Antibody for VAMP5

Assay Products for VAMP5:

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	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for VAMP5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for VAMP5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

VAMP5 for domains About GeneDecksing

2 InterPro domains/families:

IPR016444 Synaptobrevin_met/fun

IPR001388 Synaptobrevin

Graphical View of Domain Structure for InterPro Entry O95183

ProtoNet protein and cluster: O95183

1 Blocks protein family: IPB001388 Synaptobrevin

UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183

Similarity: Belongs to the synaptobrevin family

Similarity: Contains 1 v-SNARE coiled-coil homology domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: VAMP5_HUMAN, O95183

Function: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or

GLUT4 trafficking

Induction: During myogenesis

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VAMP5
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate VAMP5:
		hsa-miR-516b hsa-miR-608 hsa-miR-3670
		SwitchGear 3'UTR luciferase reporter plasmid: VAMP5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VAMP5 (see all 7) OriGene shRNA RFP: VAMP5 OriGene siRNA: VAMP5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VAMP5

Gene Editing
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DNA2.0 Custom Protein Engineering Service for VAMP5

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for VAMP5
		Search LifeMap BioReagents cell lines for VAMP5

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for VAMP5

1 GenomeRNAi human phenotype for VAMP5:

Synthetic lethal with c-Myc af

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

1.00

SNARE interactions in vesicular transport

0.40

Pathway sources
See GeneCards unified pathways
Show all pathways

1 PharmGKB Pathway for VAMP5

Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

1 Kegg Pathway (Kegg details for VAMP5):

SNARE interactions in vesicular transport

VAMP5 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for VAMP5

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for VAMP5 (ENSP00000305647⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YKT6	ENSP00000223369⁴	STRING: ENSP00000223369

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007517	muscle organ development	TAS	9725904
GO:0007519	skeletal muscle tissue development	IEA	--
GO:0016192	vesicle-mediated transport	--	--
GO:0030154	cell differentiation	IEA	--
GO:0043001	Golgi to plasma membrane protein transport	IEA	--

VAMP5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for VAMP5
Search CenterWatch for drugs/clinical trials and news about VAMP5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for VAMP5 gene:

NM_006634.2

Unigene Cluster for VAMP5:

Vesicle-associated membrane protein 5

Hs.534373 [show with all ESTs]

Unigene Representative Sequence: BE618868

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000306384(uc002spu.1) ENST00000462451

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VAMP5
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate VAMP5:
		hsa-miR-516b hsa-miR-608 hsa-miR-3670
		SwitchGear 3'UTR luciferase reporter plasmid: VAMP5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VAMP5 (see all 7) OriGene shRNA RFP: VAMP5 OriGene siRNA: VAMP5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VAMP5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for VAMP5 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for VAMP5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: VAMP5 (NM_006634)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for VAMP5
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for VAMP5 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VAMP5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VAMP5

Additional cDNA sequence:

AF054825.1 AF077197.1 AF151025.1 AK292660.1 BC017891.1 CR542215.1

11 DOTS entries:

DT.314218 DT.100748293 DT.100881723 DT.121152203 DT.121152226 DT.100881736 DT.121627652 DT.91772578

DT.100881733 DT.100881747 DT.92431991

24/316 AceView cDNA sequences (see all 316):

AA176219 BC017891 CR542215 BM887680 AI418592 CD369345 AA634593 AI568721

AA305331 D19625 BQ227618 AI419209 BI836255 BQ021316 AF077197 BX113655

BM702226 BX092149 W80846 BM767073 AA309787 AA365845 N90862 AI079353

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for VAMP5 About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3a	·	3b	·	3c
SP1:					-
SP2:					-
SP3:

ECgene alternative splicing isoforms for VAMP5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

VAMP5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGGCCAGC

About this image

VAMP5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Primitive Heart Tube

Primitive Heart Tube Cells

Myocardium

Kidney

S-shaped Body

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)

Blood, Endothelium

PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)

Endothelium

PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)

Endothelium

PureStem™ progenitor W10 (Embryonic Progenitor Cell)

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

See VAMP5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for VAMP5

SOURCE GeneReport for Unigene cluster: Hs.534373

SABiosciences Custom PCR Arrays for VAMP5

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VAMP5

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for VAMP5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for VAMP5 gene from 3/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
zebrafish (Danio rerio)	Actinopterygii	vamp5⁶	vesicle-associated membrane protein 5	31(a)	1 ↔ 1	5(29941799-29952019)
thale cress (Arabidopsis thaliana)	eudicotyledons	VAMP725⁶ VAMP728⁶ (see all 8)	vesicle-associated membrane protein 728 (see all 8)	8(a) 12(a) (see all 8)	possible ortholog possible ortholog (see all 8)	2(13857877-13859774) 3(9097514-9098945)
rice (Oryza sativa)	Liliopsida	-- -- (see all 6)	vesicle-associated membrane protein, putative, exp... vesicle-associated membrane protein, putative, exp... (see all 6)	12(a) 10(a) (see all 6)	possible ortholog possible ortholog (see all 6)	3(3550771-3553411) 7(8286841-8290221)

ENSEMBL Gene Tree for VAMP5 (if available)
TreeFam Gene Tree for VAMP5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for VAMP5 gene

VAMP2² VAMP1² VAMP8² VAMP3² VAMP4² ENSG00000263620²

6 SIMAP similar genes for VAMP5 using alignment to 2 protein entries: VAMP5_HUMAN (see all proteins):

VAMP4 VAMP8 VAMP2 VAMP3 VAMP1 SYBL1

VAMP5 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for VAMP5
PGOHUM00000237420

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs7593969^1,2	C,F,A,H,	--	85809670(+)	`AAGGCC/TTCTGG`	1	--	us2k¹		19		NS EA NA WA CSA	2341
rs7608074^1,2	C,F,A,H,	--	85809703(+)	`AAGCAT/GCTCTC`	1	--	us2k¹		8		NA WA CSA EA	371
rs1562323^1,2	C,F,A,H,	--	85809711(-)	`ATGCCA/GAGGAG`	1	--	us2k¹		13		MN NA WA CSA EA	559
rs112685956^1,2		--	85809721(+)	`TCCCAC/TGGCTG`	1	--	us2k¹		1		CSA	2
rs57762699^1,2	F,	--	85809867(+)	`CAGTCC/TGCCTT`	1	--	us2k¹		1		WA	118
rs79139517^1,2	F,	--	85809872(+)	`CGCCTT/CGGTTT`	1	--	us2k¹		1		EA	120
rs2366639^1,2	C,F,A,H,	--	85809955(+)	`CAGGAA/GGAAGG`	1	--	us2k¹ trp³		9		NA WA CSA EA	369
rs1561198^1,2	C,F,O,A,H,	--	85809989(-)	`AATCTA/GGTCCC`	1	--	us2k¹		24		MN NS EA NA WA CSA	2531
rs138419144^1,2		--	85810122(+)	`CAGACA/TGGAGT`	1	--	us2k¹		0	--	--	--	--
rs191559454^1,2		--	85810366(+)	`CACTGC/TGCCCA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for VAMP5 (85811531 - 85820535 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for VAMP5: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing VAMP5

DNA2.0 Custom Variant and Variant Library Synthesis for VAMP5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

VAMP5 for disorders           About GeneDecksing

OMIM gene information: 607029    OMIM disorders: --

5 diseases for VAMP5:    About MalaCards

open-angle glaucoma primary open anle glaucoma primary open angle glaucoma glaucoma

malaria

Genetic Association Database (GAD): VAMP5
Human Genome Epidemiology (HuGE) Navigator: VAMP5 (12 documents)

Export disorders for VAMP5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for VAMP5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with VAMP5)

Utopia: connect your pdf to the dynamic
world of online information

A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. (PubMed id 9725904)^{1, 2, 3, 9} Zeng Q.... Hong W. (1998)
VAMP5 and VAMP8 are most likely not involved in primary open-angle glaucoma. (PubMed id 16110299)^{1, 4} Brinkman J.F....Bergen A.A. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 2} Zhang Q.-H.... Chen Z. (2000)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)¹ Woods N.T....Monteiro A.N. (2012)
Seven prostate cancer susceptibility loci identified b y a multi-stage genome-wide association study. (PubMed id 21743467)¹ Kote-Jarai Z.... . (2011)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network. (PubMed id 12682051)¹ Zeng Q....Hong W. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10791	HGNC: 12646	AceView: VAMP8andVAMP5	Ensembl:ENSG00000168899	euGenes: HUgn10791
ECgene: VAMP5	Kegg: 10791	H-InvDB: VAMP5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for VAMP5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for VAMP5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for VAMP5 gene:
Search GeneIP for patents involving VAMP5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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Recombinant Protein for VAMP5

VAMP5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for VAMP5

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Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for VAMP5

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ThermoFisher Antibody for VAMP5

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat VAMP5

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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VAMP5 Gene

vesicle-associated membrane protein 5

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VAMP5 Gene

vesicle-associated membrane protein 5

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