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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VAMP4 Gene

protein-coding   GIFtS: 63
GCID: GC01M171669

Vesicle-Associated Membrane Protein 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3.2

Aliases
Vesicle-Associated Membrane Protein 41 2
VAMP-42 3
VAMP242 5

External Ids:    HGNC: 126451   Entrez Gene: 86742   Ensembl: ENSG000001175337   OMIM: 6069095   UniProtKB: O753793   
ORGUL members:    fRNAdb10:FR151165      
NONCODE14:n326329 n326328 n409344      
RNAdb15:EVF34440    

Export aliases for VAMP4 gene to outside databases

Previous GC identifers: GC01M169237 GC01M167298 GC01M168250 GC01M168908 GC01M168400 GC01M169935 GC01M142893


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VAMP4 Gene:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a
protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The
protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family.
This protein may play a role in trans-Golgi network-to-endosome transport. (provided by RefSeq, Jul 2008)

GeneCards Summary for VAMP4 Gene: 
VAMP4 (vesicle-associated membrane protein 4) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with VAMP4 include human granulocytic anaplasmosis, and vesiculitis, and among its related super-pathways are Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics and Clathrin-dependent protein traffic. An important paralog of this gene is VAMP2.

UniProtKB/Swiss-Prot: VAMP4_HUMAN, O75379
Function: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of
calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting
pathway that is critical for remodeling the secretory response of granule

Gene Wiki entry for VAMP4 Gene

fRNAdb sequence ontology for VAMP4:
nc_conserved_region - Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for VAMP4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VAMP4 gene promoter:
         Pax-5   AP-1   ATF-2   RelA   NF-kappaB   FOXJ2 (long isoform)   FOXJ2   c-Jun   NF-kappaB1   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVAMP4 promoter sequence
   Search SABiosciences Chromatin IP Primers for VAMP4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAMP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24-q25   Ensembl cytogenetic band:  1q24.3   HGNC cytogenetic band: 1q24-q25

VAMP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VAMP4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M171669:  view genomic region     (about GC identifiers)

Start:
171,669,296 bp from pter      End:
171,711,387 bp from pter
Size:
42,092 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for VAMP4

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: VAMP4_HUMAN, O75379 (See protein sequence)
Recommended Name: Vesicle-associated membrane protein 4  
Size: 141 amino acids; 16397 Da
Subunit: Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (By similarity)
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein
(Probable). Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG).
Not found on the mature secretory organelles
Secondary accessions: A2IDD8 Q96IY9 Q96J20 Q9UEL7
Alternative splicing: 2 isoforms:  O75379-1   O75379-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for VAMP4: NX_O75379

Explore proteomics data for VAMP4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75379

  • VAMP4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    VAMP4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001172056.1  NP_003753.2  

    ENSEMBL proteins: 
     ENSP00000236192   ENSP00000435933   ENSP00000356714   ENSP00000415627  

    Human Recombinant Protein Products for VAMP4: 
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    ProSpec Recombinant Protein for VAMP4
    Cloud-Clone Corp. Proteins for VAMP4 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS9553086
    GO:0005764lysosome TAS9553086
    GO:0005768endosome TAS9553086
    GO:0005794Golgi apparatus ----
    GO:0005802trans-Golgi network IEA--

    VAMP4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    VAMP: Vesicle-associated membrane proteins

    2 InterPro protein domains:
     IPR016444 Synaptobrevin_met/fun
     IPR001388 Synaptobrevin

    Graphical View of Domain Structure for InterPro Entry O75379

    ProtoNet protein and cluster: O75379

    1 Blocks protein domain: IPB001388 Synaptobrevin

    UniProtKB/Swiss-Prot: VAMP4_HUMAN, O75379
    Similarity: Belongs to the synaptobrevin family
    Similarity: Contains 1 v-SNARE coiled-coil homology domain


    VAMP4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: VAMP4_HUMAN, O75379
    Function: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of
    calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting
    pathway that is critical for remodeling the secretory response of granule

    Phenotypes:
         1 MGI phenotypic allele for Vamp4 (no phenotypes)


    VAMP4 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for VAMP4 
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    SwitchGear 3'UTR luciferase reporter plasmidVAMP4 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for VAMP4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics0.44
    SNARE interactions in vesicular transport0.40
    2Clathrin-dependent protein traffic
    Transport Clathrin-coated vesicle cycle0.66

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for VAMP4
        Transport Clathrin-coated vesicle cycle

    1 PharmGKB Pathway for VAMP4
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    1         Kegg Pathway  (Kegg details for VAMP4):
        SNARE interactions in vesicular transport


    VAMP4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VAMP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/27 Interacting proteins for VAMP4 (O753792, 3 ENSP000002361924) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STX4Q128462, 3, ENSP000003177144MINT-66593 I2D: score=5 STRING: ENSP00000317714
    STX6O437522, 3, ENSP000002583014MINT-7255483 MINT-4052274 MINT-4052302 MINT-4052327 MINT-4052351 I2D: score=3 STRING: ENSP00000258301
    VTI1AQ96AJ92, 3, ENSP000003767924MINT-4052274 MINT-4052302 MINT-4052327 MINT-4052351 I2D: score=1 STRING: ENSP00000376792
    STX12Q86Y822MINT-4052274 MINT-4052302 MINT-4052327 MINT-4052351
    STX16O146623, ENSP000003601834I2D: score=3 STRING: ENSP00000360183
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016192vesicle-mediated transport ----
    GO:0042996regulation of Golgi to plasma membrane protein transport IEA--
    GO:0043001Golgi to plasma membrane protein transport IEA--

    VAMP4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VAMP4

    1 HMDB Compound for VAMP4    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about VAMP4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    1 fRNAdb Secondary structure:


    REFSEQ mRNAs for VAMP4 gene (3 alternative transcripts): 
    NM_001185127.1  NM_003762.4  NM_201994.1  

    Unigene Cluster for VAMP4:

    Vesicle-associated membrane protein 4
    Hs.6651  [show with all ESTs]
    Unigene Representative Sequence: NM_003762
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000236192(uc001ghv.2 uc001ghw.2 uc001ghx.2 uc001ghy.2)
    ENST00000474047 ENST00000367740 ENST00000482519 ENST00000415773
    miRNA
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    Additional mRNA sequence: 

    AF044310.1 AF052100.1 AK056124.1 AK123624.1 AK290441.1 AL035296.1 BC005974.1 BC007019.1 
    CR457011.1 NR_033704.1 

    12 DOTS entries:

    DT.92420174  DT.315028  DT.97799210  DT.92420173  DT.95268191  DT.100655461  DT.100716530  DT.121348983 
    DT.121348988  DT.121348991  DT.92054278  DT.95081374 

    24/137 AceView cDNA sequences (see all 137):

    BG428093 AI758204 F05174 BM763166 AA455922 AL597489 AA991347 AA954039 
    F13519 NM_003762 AL701821 AL602755 BG283980 AW473740 AI375646 T16554 
    NM_201994 AI040504 AA771953 BX480197 AA299279 AI382885 AK123624 F10934 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for VAMP4 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d ^ 10a · 10b
    SP1:                                      -     -     -                             -                       -     -     -               
    SP2:                                      -     -     -                             -                                                   
    SP3:                                      -     -     -                             -                                                   
    SP4:                                      -                                                                                             
    SP5:                                                                          -     -                                                   


    ECgene alternative splicing isoforms for VAMP4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VAMP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCCCTGTTC
    VAMP4 Expression
    About this image


    See VAMP4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VAMP4

    SOURCE GeneReport for Unigene cluster: Hs.6651
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for VAMP4 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Vamp41 , 5 vesicle-associated membrane protein 41, 5 92.94(n)1
    95.62(a)1
      1 (70.29 cM)5
    533301  NM_016796.31  NP_058076.21 
     1625705155 
    chicken
    (Gallus gallus)
    Aves VAMP41 vesicle-associated membrane protein 4 78.72(n)
    90.78(a)
      770513  XM_001233851.2  XP_001233852.2 
    lizard
    (Anolis carolinensis)
    Reptilia VAMP46
    Uncharacterized protein
    93(a)
    1 ↔ 1
    GL343300.1(1199822-1203605)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.127602 Xenopus laevis transcribed sequence with moderate similarity more 76.8(n)    BI446492.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc731662 hypothetical protein MGC73166 78.35(n)   393708  BC059519.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SNC2(YOR327C)4 Vesicle membrane receptor protein (v-SNARE) involved more   --   15(931081-930734) 854505  NP_014972.1 


    ENSEMBL Gene Tree for VAMP4 (if available)
    TreeFam Gene Tree for VAMP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for VAMP4 gene
    VAMP22  VAMP12  VAMP82  VAMP32  ENSG000002636202  
    7 SIMAP similar genes for VAMP4 using alignment to 2 protein entries:     VAMP4_HUMAN (see all proteins):
    VAMP5    VAMP3    VAMP1    VAMP8    VAMP2    SYBL1
    VAMP7

    VAMP4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/834 SNPs in VAMP4 are shown (see all 834)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs121270261,2
    C,A--171668813(+) CTGAGA/GCTGCA 3 -- ds50014Minor allele frequency- G:0.16NA WA EA 362
    rs1502281901,2
    C--171668863(+) AGAAC-/AAGAAGAT 3 -- cds1 ds50010--------
    rs109135111,2
    C,F,A,H--171668951(+) TGGTTG/ACCTAA 3 -- ds500124Minor allele frequency- A:0.15NS EA NA WA 2930
    rs748453891,2
    C,F--171669182(+) CACTTT/CATTGG 3 -- ds50011Minor allele frequency- C:0.06WA 118
    rs1455019201,2
    --171669228(+) AGATGC/TTATTG 3 -- ds50010--------
    rs1834594951,2
    --171669330(+) TTTCAC/TTGTTC 3 -- ut31 nc-transcript-variant0--------
    rs1877423151,2
    --171669339(+) TCACTA/CTGGAG 3 -- ut31 nc-transcript-variant0--------
    rs1924466911,2
    --171669423(+) ATTGAA/GAAGCT 3 -- ut31 nc-transcript-variant0--------
    rs1142381451,2
    C,F--171669632(+) ATGTAA/TTCTAC 3 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.02WA 118
    rs1473011561,2
    C--171669742(+) TACAGG/TAGAAG 3 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for VAMP4 (171669296 - 171711387 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for VAMP4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2719529CNV Deletion23290073
    nsv3509CNV Insertion18451855
    esv28731CNV Gain+Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606909OMIM information: 611161    
    3 diseases for VAMP4:    About MalaCards
    human granulocytic anaplasmosis    vesiculitis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for VAMP4:
    Human granulocytic anaplasmosis

    VAMP4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): VAMP4
    Human Genome Epidemiology (HuGE) Navigator: VAMP4 (1 document)

    Export disorders for VAMP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VAMP4 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with VAMP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Seven novel mammalian SNARE proteins localize to distinct membrane compartments. (PubMed id 9553086)1, 2, 3 Advani R.J.... Scheller R.H. (1998)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish. (PubMed id 15896658)1, 4 Sabra M.M....Shuldiner A.R. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. (PubMed id 11839770)1, 9 Mallard F....Johannes L. (2002)
    6. ATP11B mediates platinum resistance in ovarian cancer. (PubMed id 23585472)1 Moreno-Smith M....Sood A.K. (2013)
    7. VAMP4 directs synaptic vesicles to a pool that selecti vely maintains asynchronous neurotransmission. (PubMed id 22406549)1 Raingo J....Kavalali E.T. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    10. VAMP4- and VAMP7-expressing vesicles are both require d for cytotoxic granule exocytosis in NK cells. (PubMed id 21805468)1 Krzewski K....Strominger J.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8674 HGNC: 12645 AceView: VAMP4 Ensembl:ENSG00000117533 euGenes: HUgn8674
    ECgene: VAMP4 Kegg: 8674 H-InvDB: VAMP4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VAMP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VAMP4 gene:
    Search GeneIP for patents involving VAMP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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