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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

VAMP3 Gene

protein-coding   GIFtS: 60
GCID: GC01P007765

vesicle-associated membrane protein 3

 Explore 11 diseases affiliated with
VAMP3 via our new
 Human Malady Compendium 
Biological research products
for VAMP3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Vesicle-Associated Membrane Protein 31 2     Synaptobrevin-33
CEB1 2 3     Cellubrevin3
VAMP-32 3     SYB33
Cellubrevin3     Synaptobrevin-33

External Ids:    HGNC: 126441   Entrez Gene: 93412   Ensembl: ENSG000000492457   OMIM: 6036575   UniProtKB: Q158363   

Export aliases for VAMP3 gene to outside databases

Previous GC identifers: GC01P007413 GC01P007640 GC01P007540 GC01P006979


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for VAMP3:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein
complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a
member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other
known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was
shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is
not mobilized to the plasma membrane on calcium or thrombin stimulation. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: VAMP3_HUMAN, Q15836
Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network

Gene Wiki entry for VAMP3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_021937.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the VAMP3 gene promoter:
         POU3F2 (N-Oct-5a)   CUTL1   Nkx2-5   POU3F2   NF-kappaB   FOXL1   POU2F1   POU2F1a   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidVAMP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for VAMP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat VAMP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.23   Ensembl cytogenetic band:  1p36.23   HGNC cytogenetic band: 1p36.23

VAMP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
VAMP3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P007765:  view genomic region     (about GC identifiers)

Start:
7,831,329 bp from pter      End:
7,841,492 bp from pter
Size:
10,164 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: VAMP3_HUMAN, Q15836 (See protein sequence)
Recommended Name: Vesicle-associated membrane protein 3  
Size: 100 amino acids; 11309 Da
Subunit: Interacts with BVES (via the C-terminus cytoplasmic tail) (By similarity)
Subcellular location: Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome
(By similarity)

Explore the universe of human proteins at neXtProt for VAMP3: NX_Q15836

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15836

  • VAMP3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004772.1  
    ENSEMBL proteins: 
     ENSP00000054666   ENSP00000465820  

    Human Recombinant Protein Products: 
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    Novus Biologicals VAMP3 Lysate
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    ProSpec Recombinant Protein for VAMP3
    Uscn Proteins for VAMP3

    Gene Ontology (GO): 5/15 cellular component terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005792microsome ----
    GO:0005886plasma membrane ISS--
    GO:0016021integral to membrane IEA--
    GO:0016324apical plasma membrane IEA--
    GO:0019717synaptosome ----


    VAMP3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for VAMP3


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    VAMP3 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR016444 Synaptobrevin_met/fun
     IPR001388 Synaptobrevin

    Graphical View of Domain Structure for InterPro Entry Q15836

    ProtoNet protein and cluster: Q15836

    1 Blocks protein family: IPB001388 Synaptobrevin

    UniProtKB/Swiss-Prot: VAMP3_HUMAN, Q15836
    Similarity: Belongs to the synaptobrevin family
    Similarity: Contains 1 v-SNARE coiled-coil homology domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: VAMP3_HUMAN, Q15836
    Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network

    miRNA
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    miRTarBase miRNAs that target VAMP3:
    hsa-mir-124 (MIRT002594), hsa-mir-155 (MIRT001487)

    OriGene 3'-UTR Clone: VAMP3
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat VAMP3
    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate VAMP3 (see all 40):
    hsa-miR-520f hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-199a-3p hsa-miR-30d hsa-miR-3161 hsa-miR-9 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidVAMP3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for VAMP3 (see all 7)
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    OriGene siRNA: VAMP3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat VAMP3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAMP3

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000149SNARE binding ----
    GO:0005515protein binding IPI--
    GO:0017075syntaxin-1 binding IEA--


    VAMP3 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Vamp3tm1Jepn for VAMP3
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Vamp3):
     hematopoietic system  homeostasis/metabolism  immune system  nervous system  normal 

    VAMP3 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics
    Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics1.00
    SNARE interactions in vesicular transport0.40
    2Arf6 trafficking events
    Arf6 trafficking events1.00
    3Phagosome
    Phagosome1.00
    4Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for VAMP3
        Epithelial Tight Junctions

    1 BioSystems Pathway for VAMP3 
        Arf6 trafficking events

    1 PharmGKB Pathway for VAMP3
        Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics

    2         Kegg Pathways  (Kegg details for VAMP3):
        SNARE interactions in vesicular transport
    Phagosome


    VAMP3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for VAMP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/53 Interacting proteins for VAMP3 (Q158361, 2, 3 ENSP000000546664) via UniProtKB, MINT, STRING, and/or I2D (see all 53)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NELFEP186153, ENSP000003645784I2D: score=4 STRING: ENSP00000364578
    ENSG00000206268P186153I2D: score=4 
    ENSG00000206357P186153I2D: score=4 
    ENSG00000229363P186153I2D: score=4 
    ENSG00000231044P186153I2D: score=4 
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001921positive regulation of receptor recycling ISS--
    GO:0006461protein complex assembly IEA--
    GO:0006887exocytosis TAS9885218
    GO:0006904vesicle docking involved in exocytosis TAS9885218
    GO:0006944cellular membrane fusion TAS9885218


    VAMP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    VAMP3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for VAMP3
    5 Novoseek chemical compound relationships for VAMP3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    n-ethylmaleimide 28.9 1 9614185 (1)
    glucose 25.2 4 9153412 (2), 8862521 (1)
    phosphatidylinositol 3.93 1 12911814 (1)
    atp 0 1 8195285 (1)
    hydrogen 0 2 10807583 (2)

    Search CenterWatch for drugs/clinical trials and news about VAMP3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for VAMP3 gene: 
    NM_004781.3  

    Unigene Cluster for VAMP3:

    Vesicle-associated membrane protein 3
    Hs.66708  [show with all ESTs]
    Unigene Representative Sequence: NM_004781
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000054666(uc001aol.3) ENST00000470357 ENST00000487194

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    8/40 QIAGEN miScript miRNA Assays for microRNAs that regulate VAMP3 (see all 40):
    hsa-miR-520f hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-199a-3p hsa-miR-30d hsa-miR-3161 hsa-miR-9 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidVAMP3 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat VAMP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat VAMP3

    Additional cDNA sequence: 

    AK316558.1 BC003570.1 BC005941.1 BC007050.1 BT007327.1 CR542145.1 CR542154.1 U64520.1 

    20 DOTS entries:

    DT.100669640  DT.418207  DT.121457264  DT.65284212  DT.92447521  DT.432301  DT.100669638  DT.121457270 
    DT.121457287  DT.91638549  DT.95250162  DT.101976203  DT.100669635  DT.121457275  DT.121457279  DT.121457300 
    DT.91725142  DT.92447525  DT.97859579  DT.121457267 

    24/422 AceView cDNA sequences (see all 422):

    BP360380 BX370047 BM772043 AW272871 BU521949 BP335731 CB123323 BQ055441 
    CR542145 BP354078 BQ066709 BQ447496 BU629002 BM829743 BU197239 BM464343 
    AA418516 BG057129 AU137465 BQ029103 BE786163 T16621 BP337523 CD515764 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for VAMP3 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7
    SP1:                    -     -     -     -           -                                 
    SP2:                    -           -     -           -                                 
    SP3:                                -     -           -                                 
    SP4:                                                  -                                 
    SP5:                    -     -     -     -           -     -     -     -     -         


    ECgene alternative splicing isoforms for VAMP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    VAMP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGAACCAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See VAMP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for VAMP3

    SOURCE GeneReport for Unigene cluster: Hs.66708
        SABiosciences Expression via Pathway-Focused PCR Array including VAMP3: 
              Diabetes in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for VAMP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for VAMP3 gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves VAMP31 vesicle-associated membrane protein 3 (cellubrevin) 78.89(n)
    92.22(a)
      419368  NM_001039489.1  NP_001034578.1 
    lizard
    (Anolis carolinensis)
    Reptilia VAMP36
    --
    82(a)
    1 ↔ 1
    GL344178.1(48009-49839)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.165072 Xenopus laevis transcribed sequence with moderate similarity more 78.65(n)    CF270539.1 
    zebrafish
    (Danio rerio)
    Actinopterygii vamp31 vesicle-associated membrane protein 3 (cellubrevin) 75.09(n)
    85.71(a)
      415163  NM_001002073.1  NP_001002073.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Syb6
    n-syb6
    n-synaptobrevin
    36(a)
    27(a)
    many ↔ many
    many ↔ many
    2R(6136940-6139914)
    3L(1630348-1637752)
    worm
    (Caenorhabditis elegans)
    Secernentea snb-11 Protein SNB-1 67.44(n)
    76.74(a)
      266648  NM_072287.3  NP_504688.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons VAMP7286
    ATVAMP7266
    (see all 8)
    vesicle-associated membrane protein 72
    (see all 8)
    16(a)
    15(a)
    (see all 8)
    possible ortholog
    possible ortholog
    (see all 8)
    3(9097514-9098945)
    1(1334760-1336070)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 6)
    vesicle-associated membrane protein 727, putative,...
    vesicle-associated membrane protein, putative, exp...
    (see all 6)
    9(a)
    14(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    8(27953586-27956266)
    3(3550771-3553411)


    ENSEMBL Gene Tree for VAMP3 (if available)
    TreeFam Gene Tree for VAMP3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for VAMP3 gene
    VAMP22  VAMP12  VAMP52  VAMP82  VAMP42  ENSG000002636202  
    6 SIMAP similar genes for VAMP3 using alignment to 4 protein entries:     VAMP3_HUMAN (see all proteins):
    VAMP1    VAMP2    VAMP4    VAMP8    VAMP5    SYBL1

    VAMP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/238 NCBI SNPs in VAMP3 are shown (see all 238    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1392672871,2
    --7829528(+) TTGGCA/GCCCAA 2 -- ut31 us2k10--------
    rs1425381471,2
    --7829619(+) GTAAAA/GCATCA 2 -- us2k1 ut310--------
    rs1441938491,2
    --7829770(+) TACTAC/TGTGTG 2 -- us2k1 ds50010--------
    rs1486883671,2
    --7829888(+) TGACAC/TTGAAT 2 -- us2k1 ds50010--------
    rs1176416371,2
    F,--7830063(+) TTACAA/GTCCTC 2 -- us2k1 ds50011Minor allele frequency- G:0.03EA 120
    rs793175881,2
    F,--7830098(+) CAGCAG/CATTAC 2 -- us2k1 ds50011Minor allele frequency- C:0.03WA 118
    rs785808511,2
    F,--7830229(+) AAATTT/CTGCAT 2 -- us2k1 ds50011Minor allele frequency- C:0.03WA 118
    rs21537331,2
    C,F,O,A,H,--7830262(-) AAACCA/GTTGAC 2 -- us2k1 ds5001 tfbs318Minor allele frequency- G:0.22NS EA NA WA 2342
    rs728538881,2
    C,--7830335(+) TTTTCA/CCTTGT 1 -- us2k12Minor allele frequency- C:0.08WA 120
    rs1893339221,2
    --7830393(+) CACTGC/TTGTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for VAMP3 (7831329 - 7841492 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for VAMP3: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    VAMP3 for disorders           About GeneDecksing

    OMIM gene information: 603657    OMIM disorders: --

    11 diseases for VAMP3:    About MalaCards
    bipolar affective disorder    tetanus    cystic fibrosis    crohn's disease
    fibrosis    tuberculosis    melanoma    pancreatitis
    malaria    neuronitis    mycobacterium tuberculosis

    1 disease from the University of Copenhagen DISEASES database for VAMP3:
    Tetanus

    2 Novoseek disease relationships for VAMP3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tetanus 79.7 37 8195285 (4), 8360142 (4), 10807583 (3), 10888677 (2) (see all 20)
    tuberculosis 0 1 11825909 (1)

    Human Genome Epidemiology (HuGE) Navigator: VAMP3 (2 documents)

    Export disorders for VAMP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for VAMP3 gene, integrated from 9 sources (see all 110):
    (articles sorted by number of sources associating them with VAMP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a cellubrevin/vesicle associated membrane protein 3 homologue in human platelets. (PubMed id 9885218)1, 2, 3, 9 Bernstein A.M. and Whiteheart S.W. (1999)
    2. A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. (PubMed id 18195106)1, 2 Ganley I.G....Pfeffer S.R. (2008)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    6. Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31. (PubMed id 9396746)1, 9 Annaert W.G.... Jahn R. (1997)
    7. VAMP3, syntaxin-13 and SNAP23 are involved in secreti on of matrix metalloproteinases, degradation of the extracellular matrix and ce ll invasion. (PubMed id 19910495)1, 9 Kean M.J....Coppolino M.G. (2009)
    8. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE prot eins involved in specific steps of the autophagy/multivesicular body pathways. (PubMed id 19781582)1, 9 Fader C.M....Colombo M.I. (2009)
    9. Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells. (PubMed id 11809765)1, 9 Poschet J.F....Deretic V. (2002)
    10. Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform. (PubMed id 11839770)1, 9 Mallard F....Johannes L. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9341 HGNC: 12644 AceView: VAMP3 Ensembl:ENSG00000049245 euGenes: HUgn9341
    ECgene: VAMP3 Kegg: 9341 H-InvDB: VAMP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for VAMP3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for VAMP3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for VAMP3 gene:
    Search GeneIP for patents involving VAMP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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     Regulatory tfbs in VAMP3 promoter
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