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VAMP2 Gene

protein-coding GIFtS: 59

GC17M007987

vesicle-associated membrane protein 2 (synaptobrevin 2)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: SYB2)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ11460 ^²
SYB2 ^², ³, ⁵
Synaptobrevin-2 ^³
VAMP-2 ^¹, ², ³

Descriptions
synaptobrevin 2 ^²
vesicle associated membrane protein 2 ^²
vesicle-associated membrane protein 2 (synaptobrevin 2) ^²

External Ids
HGNC: 12643¹
Entrez Gene: 6844²
UniProtKB: P63027³
Ensembl: ENSG00000179036⁷

Search outside databases for aliases for VAMP2 gene

Previous GC identifers: GC17U990100 GC17M009150 GC17M008005 GC17M008263

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for VAMP2:

The protein encoded by this gene is a member of the vesicle-associated membrane protein

(VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD

synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in

the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought

to participate in neurotransmitter release at a step between docking and fusion. The protein forms

a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also

forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile

myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of

the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq]

UniProtKB/Swiss-Prot: VAMP2_HUMAN, P63027

Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane

Gene Wiki entry for VAMP2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the VAMP2 gene

Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17pter-p12

VAMP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M007987: (about GC identifiers)

Start:	8,003,146 bp from pter
End:	8,007,017 bp from pter
Size:	3,872 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000017.9 NT_010718.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: VAMP2_HUMAN, P63027 (See protein sequence)

Recommended Name: Vesicle-associated membrane protein 2

Size: 116 amino acids; 12649 Da

Subunit: Interacts with VAPA and VAPB

Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane;

Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Note=Neuronal synaptic

vesicles

Secondary accessions: P19065

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055047.2

ENSEMBL proteins:

ENSP00000379599 ENSP00000385595 ENSP00000379602

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich AQUA Peptides for VAMP2
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (VAMP2, Synaptobrevin)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	TAS	1976629
GO:0016020	membrane	IEA	--
GO:0019717	synaptosome	IEA	--
GO:0030054	cell junction	IEA	--
GO:0031410	cytoplasmic vesicle	IEA	--

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Antibodies for VAMP2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of VAMP2
	Sigma-Aldrich Antibodies for VAMP2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (VAMP2, Synaptobrevin), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (VAMP2)
	Novus Biologicals Antibodies for VAMP2

Assays for VAMP2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P63027

ProtoNet protein and cluster: P63027

1 Blocks protein family: IPB001388 Synaptobrevin

UniProtKB/Swiss-Prot: VAMP2_HUMAN, P63027

Similarity: Belongs to the synaptobrevin family

Similarity: Contains 1 v-SNARE coiled-coil homology domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (VAMP2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014232

Applied Biosystems Silencer® siRNAs for VAMP2

Sigma-Aldrich siRNA for VAMP2

Sigma-Aldrich shRNA for VAMP2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for VAMP2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014232
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014232
untagged cDNA clone in CMV expression vector: NM_014232

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014232

UniProtKB/Swiss-Prot: VAMP2_HUMAN, P63027

Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane

Genatlas biochemistry entry for VAMP2:

vesicule associated membrane protein 2,synaptobrevin 2,expressed in neurons forming a synaptic core

complex with syntaxin and synaptosome associated proteins,playing a central role in neural

exocytosis,soluble N ethylmaleimide-sensitive factor-attachment protein receptor,SNARE protein

8 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Vamp2):

endocrine/exocrine gland	growth/size	hematopoietic system	immune system	lethality-postnatal
lethality-prenatal/perinatal	nervous system	normal

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	9920726

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for VAMP2 (Your Favorite Gene powered by Ingenuity)

Insulin Receptor Signaling

GeneDecks VAMP2 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for VAMP2

1 Interacting protein for VAMP2 (P63027¹) via UniProtKB, MINT, and/or STRING
Interactant Interaction Details
GeneCard External ID(s)
PRKD3 O94806¹ EBI-520113, EBI-1255366
About this table
1 Gene Ontology (GO) biological process term (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0016192 vesicle-mediated transport IEA --
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for VAMP2
7 Novoseek chemical compound relationships for VAMP2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glucose	38.87	13	15537656 (3), 8772493 (2), 10713150 (1), 11208137 (1) (see all 9)
phosphatidylinositol	21.77	1	11297538 (1)
phorbol	18.37	2	11162495 (1), 11263991 (1)
calcium	0.36	4	15846778 (1), 18715899 (1), 17204559 (1), 15028755 (1)
hydrogen	0.00	1	17311420 (1)
lipid	0.00	3	15073181 (1), 16439800 (1), 12376543 (1)
tyrosine	0.00	1	16018556 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (VAMP2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014232

Sigma-Aldrich siRNA for VAMP2

Sigma-Aldrich shRNA for VAMP2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014232

REFSEQ mRNAs for VAMP2 gene:

NM_014232.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014232

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014232
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014232
                                 untagged cDNA clone in CMV expression vector: NM_014232

Additional cDNA sequence:

AJ225044.1 AK021522.1 AK225777.1 AK289555.1 AL050223.1 BC002737.2 BC019608.1 BC033870.1

BC150138.1

15 DOTS entries:

DT.40107989 DT.100794299 DT.448468 DT.91787682 DT.95353896 DT.65287860 DT.100794300 DT.100794301

DT.98081774 DT.75161839 DT.75180389 DT.92426527 DT.95149295 DT.95170329 DT.91766472

24/455 AceView cDNA sequences (see all 455 ):

AA490787 AI804192 AI815549 F08744 BM717200 AA971398 AA864450 AA909154

BM511675 H84469 BQ269273 BM849581 BM021268 H27871 BM671785 AL549959

BU729490 CD514276 BU740280 F04440 BM141929 H92470 BX508108 AK021522

highest scoring ESTs for VAMP2:

AI815549 AL050223 BC002737 BC019608 BC033870 BE382373 BG707935 BG708134 BG708156 BG713895

Unigene Cluster for VAMP2:

Vesicle-associated membrane protein 2 (synaptobrevin 2)

Hs.25348 [show with all ESTs]

Unigene Representative Sequence: NM_014232

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000396305 ENST00000404970 ENST00000396308

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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VAMP2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for VAMP2

¹ / ² / ³

7 probe-sets matching VAMP2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32254_at²^{, 3}	U95-A	2	1.00	0.50	1.00	1.00	AL050223	0.80	1.00	0.91	1
214792_x_at²^{, 3}	U133-A	2	1.00	0.55	--	--	AI955119	0.40	1.00	0.76	1
201557_at²^{, 3}	U133-A	2	1.00	0.50	--	--	NM_014232	0.60	1.00	0.82	1
201556_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	BC002737	0.80	1.00	0.91	1
214792_x_at²	U133Plus2	2	1.00	0.55	--	--	--	--	--	--	--
201557_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
201556_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCCCCAATTC

SOURCE GeneReport for Unigene cluster: Hs.25348
Expression variation in blood from EXPOLDB for VAMP2
UniProtKB/Swiss-Prot: VAMP2_HUMAN, P63027
Tissue specificity: Nervous system and skeletal muscle

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for VAMP2 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	VAMP2¹	--	vesicle-associated membrane protein 2 (synaptobrevin more	96.55(n) 100(a)	479491 XM_536630.2 XP_536630.2
chimpanzee (Pan troglodytes)	VAMP2¹	--	vesicle-associated membrane protein 2 (synaptobrevin more	99.43(n) 99.14(a)	747237 XM_001156324.1 XP_001156324.1
cow (Bos taurus)	VAMP2¹	--	vesicle-associated membrane protein 2 (synaptobrevin more	94.54(n) 100(a)	282116 NM_174483.2 NP_776908.1
rat (Rattus norvegicus)	Vamp2¹	--	vesicle-associated membrane protein 2	93.39(n) 98.28(a)	24803 NM_012663.2 NP_036795.1
mouse (Mus musculus)	Vamp2^{1, 5}	11⁵	vesicle-associated membrane protein 2^{1, 5}	93.97(n)¹ 98.28(a)¹	22318¹ NM_009497.3¹ NP_033523.1¹ AF007168⁵ AI838601⁵ (see all 11)

About this table Species with no ortholog for VAMP2

ENSEMBL Gene Tree for VAMP2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for VAMP2 gene

VAMP1² VAMP3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/35 NCBI SNPs in VAMP2 are shown (see all 35 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 48)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs9899533^1,2	A,C,F,H	8008770(+)	`GTCTTG/CAAATG`	1	--	ng3¹		8		EU EA WA	830
	rs1150^1,2	A,C,F,H	8003308(+)	`GTCTAG/AAACAC`	1	--	ut3¹ ese³		4		EU EA WA	400
	rs2278637^1,2	A,C,F,H	8002827(+)	`GCCACT/GGCAGA`	1	--	ng5¹		5		EA EU WA	1890
	rs8067606^1,2	A,C,F,H	8007508(+)	`ACCTTG/ACTGCT`	1	--	ng3¹		4		EU EA WA	416
--	rs1061032^1,2	A,C,F,H	8004808(-)	`CCCCCC/ACTCCC`	1	--	ut3¹ ese³		6		MN EU EA WA	776
--	rs8066513^1,2	A,C,H	8007166(+)	`CGCCAC/TCATGC`	1	--	ng3¹		4		EU EA WA	420
	rs959303^1,2	A,C,F	8002924(+)	`GACCAT/CAGGGC`	1	--	ng5¹		2		MN EA	1478
	rs11868410^1,2	C	8006356(+)	`GTGCAA/GGGGGA`	1	P/L	mis¹ ese³		0	--	--	--	--
--	rs1051667^1,2	F	8003422(-)	`GGGGGC/GCCCCA`	1	--	ut3¹ ese³		1		MN	184
--	rs8066511^1,2	A	8007158(+)	`GGGCCC/TCGCGC`	1	--	ng3¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for VAMP2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 185881

2 Novoseek disease relationships for VAMP2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tetanus	79.03	45	11068046 (3), 10888677 (2), 7560075 (2), 18511417 (2) (see all 30)
insulinoma	13.99	2	12887316 (1), 11502551 (1)

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Human Genome Epidemiology Navigator: VAMP2 (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/228 PubMed articles for VAMP2 gene (see all 228 ):

Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2. (PubMed id 1976629)^{1, 2, 3, 4} Archer B.T. III... Suedhof T.C. (1990)
Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2. (PubMed id 8760387)^{1, 3, 4} Jagadish M.N....Ward C.W. (1996)
Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution. (PubMed id 10932255)^{3, 4} Hanson M.A. and Stevens R.C. (2000)
Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane. (PubMed id 7835332)^{3, 4} Kutay U.... Rapoport T.A. (1995)
Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin. (PubMed id 18511417)^{1, 3} Chen S....Barbieri J.T. (2008)
Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder. (PubMed id 18628682)^{1, 3} Abou Jamra R....Schumacher J. (2008)
Role of vesicle-associated membrane protein-2, through Q-soluble N-ethylmaleimide-sensitive factor attachment protein receptor/R-soluble N-ethylmaleimide-sensitive factor attachment protein receptor interaction, in the exocytosis of specific and tertiary granules of human neutrophils. (PubMed id 12517971)^{1, 3} Mollinedo F....Lazo P.A. (2003)
Role of SNAP23 in insulin-induced translocation of GLUT4 in 3T3-L1 adipocytes. Mediation of complex formation between syntaxin4 and VAMP2. (PubMed id 10713150)^{1, 3} Kawanishi M....Kasuga M. (2000)
WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. (PubMed id 17313651)^{1, 3} Fritzius T....Moelling K. (2007)
Evidence for CALM in directing VAMP2 trafficking. (PubMed id 18182011)^{1, 3} Harel A....Yao P.J. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6844	HGNC: 12643	AceView: VAMP2	Ensembl:ENSG00000179036	euGenes: HUgn6844
ECgene: VAMP2	H-InvDB: VAMP2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for VAMP2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for VAMP2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for VAMP2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for VAMP2		Antibodies for VAMP2
	Explore super-pooled esiRNAs		Proteins for VAMP2
	Lentivirus-delivered shRNAs for VAMP2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
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Search Tocris compounds for VAMP2

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VAMP2 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for VAMP2

Summaries
for VAMP2

Genomic Location
for VAMP2

Proteins
for VAMP2

Protein Domains/
Families
for VAMP2

Gene Function
for VAMP2

Pathways & Interactions
for VAMP2

Drugs & Compounds
for VAMP2

Transcripts
for VAMP2

Expression
for VAMP2

Orthologs
for VAMP2

Paralogs
for VAMP2

SNPs/Variants
for VAMP2

Disorders & Mutations
for VAMP2

Medical News
for VAMP2

Publications
for VAMP2

Search for VAMP2

Genome Databases showing VAMP2

Other Databases showing VAMP2

Specialized Databases showing VAMP2

Licensable Technologies
for VAMP2

Services
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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

VAMP2 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor VAMP2

Summariesfor VAMP2

Genomic Locationfor VAMP2

Proteinsfor VAMP2

Protein Domains/Familiesfor VAMP2

Gene Functionfor VAMP2

Pathways & Interactionsfor VAMP2

Drugs & Compoundsfor VAMP2

Transcriptsfor VAMP2

Expression for VAMP2

Orthologsfor VAMP2

Paralogsfor VAMP2

SNPs/Variantsfor VAMP2

Disorders & Mutationsfor VAMP2

Medical Newsfor VAMP2

Publicationsfor VAMP2

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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