Aliases for VAMP1 Gene
External Ids for VAMP1 Gene
Previous HGNC Symbols for VAMP1 Gene
Previous GeneCards Identifiers for VAMP1 Gene
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]
GeneCards Summary for VAMP1 Gene
VAMP1 (Vesicle Associated Membrane Protein 1) is a Protein Coding gene. Diseases associated with VAMP1 include Spastic Ataxia 1, Autosomal Dominant and Spastic Ataxia 1. Among its related pathways are Toxicity of botulinum toxin type D (BoNT/D) and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include SNARE binding and SNAP receptor activity. An important paralog of this gene is VAMP2.
UniProtKB/Swiss-Prot for VAMP1 Gene
Involved in the targeting and/or fusion of transport vesicles to their target membrane.