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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UVSSA Gene

protein-coding   GIFtS: 41
GCID: GC04P001341

UV-stimulated scaffold protein A

(Previous name: KIAA1530 )
(Previous symbol: KIAA1530)
 Explore 2 diseases affiliated with
UVSSA via our new
 Human Malady Compendium 
Biological research products
for UVSSA
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
UV-Stimulated Scaffold Protein A1 2
KIAA15301 2 3
UVSS32

External Ids:    HGNC: 293041   Entrez Gene: 576542   Ensembl: ENSG000001639457   OMIM: 6146325   UniProtKB: Q2YD983   

Export aliases for UVSSA gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UVSSA:
The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II
subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide
excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3.
(provided by RefSeq, May 2012)

UniProtKB/Swiss-Prot: UVSSA_HUMAN, Q2YD98
Function: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER
allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by
promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced
degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and
facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the
nucleotide excision repair machinery. Not involved in processing oxidative damage




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_037622.5  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for UVSSA
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for UVSSA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UVSSA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

UVSSA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UVSSA gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P001341:  view genomic region     (about GC identifiers)

Start:
1,341,054 bp from pter      End:
1,381,837 bp from pter
Size:
40,784 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UVSSA_HUMAN, Q2YD98 (See protein sequence)
Recommended Name: UV-stimulated scaffold protein A  
Size: 709 amino acids; 80591 Da
Subunit: Interacts with the elongating form of RNA polymerase II (RNA pol IIo). Interacts with ERCC6, ERCC8 and USP7
Subcellular location: Chromosome. Note=Accumulates at UV DNA damage sites
Sequence caution: Sequence=BAA96054.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K9E6 B2RU11 Q8WTX4 Q9P1Z8
Alternative splicing: 2 isoforms:  Q2YD98-1   Q2YD98-2   

Explore the universe of human proteins at neXtProt for UVSSA: NX_Q2YD98

Post-translational modifications:

  • Monoubiquitinated: ubiquitination does not increase in response to UV1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q2YD98

  • UVSSA Protein expression data from MOPED and PaxDb:    About this image 
    UVSSA Protein Expression
    REFSEQ proteins: NP_065945.2  
    ENSEMBL proteins: 
     ENSP00000425130   ENSP00000374501   ENSP00000421741   ENSP00000423340   ENSP00000427701  
     ENSP00000422795  

    Human Recombinant Protein Products for UVSSA: 
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    OriGene Protein Over-expression Lysate: UVSSA
    OriGene Custom Protein Services for UVSSA 
    GenScript Custom Purified and Recombinant Proteins Services for UVSSA
    Novus Biologicals UVSSA Protein
    Novus Biologicals UVSSA Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044427chromosomal part IDA--

    UVSSA for ontologies           About GeneDecksing



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    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    UVSSA for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR018610 DUF2043

    Graphical View of Domain Structure for InterPro Entry Q2YD98

    ProtoNet protein and cluster: Q2YD98

    UniProtKB/Swiss-Prot: UVSSA_HUMAN, Q2YD98
    Similarity: Belongs to the UVSSA family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UVSSA_HUMAN, Q2YD98
    Function: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER
    allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by
    promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced
    degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and
    facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the
    nucleotide excision repair machinery. Not involved in processing oxidative damage

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000993RNA polymerase II core binding IMP--
    GO:0005515protein binding IPI--
         
    UVSSA for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for UVSSA 

    miRNA
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    OriGene 3'-UTR Clone: UVSSA
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UVSSA
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    SwitchGear 3'UTR luciferase reporter plasmidUVSSA 3' UTR sequence
    Inhib. RNA
    Products:
        
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UVSSA (see all 7)
    OriGene shRNA RFP: UVSSA
    OriGene siRNA: UVSSA
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    Sirion Biotech Custom design and validation of potent shRNA sequences against UVSSA 

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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UVSSA (see all 3)
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    Sirion Biotech Customized inducible overexpressing cell line services for UVSSA

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UVSSA


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UVSSA

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for UVSSA (ENSP000003745014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7ENSP000003435354STRING: ENSP00000343535
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006283transcription-coupled nucleotide-excision repair IMP--
    GO:0009411response to UV IMP--
    GO:0016567protein ubiquitination IMP--

    UVSSA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UVSSA
    Search CenterWatch for drugs/clinical trials and news about UVSSA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for UVSSA gene: 
    NM_020894.2  

    Unigene Cluster for UVSSA:

    UV-stimulated scaffold protein A
    Hs.380475  [show with all ESTs]
    Unigene Representative Sequence: NM_020894
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000511216 ENST00000389851(uc003gde.4 uc010ibv.3) ENST00000507531
    ENST00000505716 ENST00000511563 ENST00000512728 ENST00000503548 ENST00000507422


    miRNA
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    OriGene 3'-UTR Clone: UVSSA
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UVSSA
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate UVSSA
    SwitchGear 3'UTR luciferase reporter plasmidUVSSA 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UVSSA (see all 7)
    OriGene shRNA RFP: UVSSA
    OriGene siRNA: UVSSA
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    Sirion Biotech Custom design and validation of potent shRNA sequences against UVSSA 
    Clone
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UVSSA
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UVSSA

    Additional cDNA sequence: 

    AB040963.1 AK292661.1 AL110229.1 BC021930.1 BC110331.1 BC140901.1 

    8 DOTS entries:

    DT.40218508  DT.92418151  DT.100777568  DT.95072358  DT.95213253  DT.121220147  DT.407710  DT.70101562 

    24/60 AceView cDNA sequences (see all 60):

    AA227817 BF509460 AL390128 AI697892 BQ775260 R70766 BM673105 BC021930 
    AW450575 AI743059 BI907243 AA806760 CD638623 AA234799 AI400999 AA227991 
    BG760777 BX100303 AA234730 AA481135 BF437936 BE256857 AB040963 AI630779 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section
    See probesets specificity/sensitivity at GeneAnnot
    CGAP TAG: --

    See UVSSA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UVSSA

    SOURCE GeneReport for Unigene cluster: Hs.380475
        SABiosciences Custom PCR Arrays for UVSSA
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UVSSA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for UVSSA gene from 7/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Uvssa1 , 5 RIKEN cDNA 4933407H18 gene5
    UV stimulated scaffold protein A1
    77.32(n)1
    73.01(a)1
      5 (17.60 cM)5
    711011  NM_001081101.21  NP_001074570.11 
     333785515 
    chicken
    (Gallus gallus)
    Aves KIAA15301 KIAA1530 64(n)
    62.29(a)
      422903  XM_420845.3  XP_420845.3 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA15306
    --
    54(a)
    1 ↔ 1
    GL343447.1(302315-351826)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.271062 Danio rerio cDNA clone IMAGE3815294, partial cds 74.31(n)    BC056778.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK742.21 Protein ZK742.2 38.91(n)
    27.21(a)
      179158  NM_072611.3  NP_505012.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G618001 hypothetical protein 39.68(n)
    27.95(a)
      825353  NM_116045.2  NP_191739.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g02938001 hypothetical protein 44.22(n)
    33.33(a)
      4329068  NM_001053136.1  NP_001046601.1 


    ENSEMBL Gene Tree for UVSSA (if available)
    TreeFam Gene Tree for UVSSA (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1047 NCBI SNPs in UVSSA are shown (see all 1047    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs593916661,2
    C--1307299(+) GGTCTG/AGCTGC 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs76724061,2
    C--1307955(+) CGGGGA/TTCAgg 1 -- us2k10--------
    rs131467291,2
    C--1308823(+) AGGGCA/GCAGCT 1 -- ut510--------
    rs1161703741,2
    C,F--1308934(+) GCGGTG/TCTCGG 1 -- ut511Minor allele frequency- T:0.03NA 120
    rs1113914981,2
    C--1309077(+) AGTGAA/GTAAGG 1 -- int12Minor allele frequency- G:0.06NA 122
    rs1134409221,2
    --1309939(+) CGTCAC/TCCTCA 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs796560581,2
    F--1310137(+) AATTCG/CCAATG 1 -- int11Minor allele frequency- C:0.02WA 118
    rs126399381,2
    C,F,A,H--1310701(+) GGGAGG/CTAGAT 1 -- int112Minor allele frequency- C:0.18NS EA NA WA CSA 648
    rs787366171,2
    F--1310795(+) CGTGCG/CTGCGG 1 -- int11Minor allele frequency- C:0.09WA 118
    rs746995281,2
    F--1311672(+) GAACCC/TAGCCT 1 -- int11Minor allele frequency- T:0.09WA 118

    HapMap Linkage Disequilibrium report for UVSSA (1341054 - 1381837 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for UVSSA: --
    Human Gene Mutation Database (HGMD): UVSSA

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UVSSA
    DNA2.0 Custom Variant and Variant Library Synthesis for UVSSA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    UVSSA for disorders           About GeneDecksing

    OMIM gene information: 614632    OMIM disorders: --

    UniProtKB/Swiss-Prot: UVSSA_HUMAN, Q2YD98
  • Defects in UVSSA are a cause of UV-sensitive syndrome type 3 (UVSS3) [MIM:614640]. A rare autosomal recessive
  • disorder characterized by photosensitivity and mild freckling but without neurological abnormalities or skin tumors

    2 diseases for UVSSA:    About MalaCards
    uv-sensitive syndrome 3    uv sensitive syndrome


    Export disorders for UVSSA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UVSSA gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with UVSSA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair. (PubMed id 22466611)1, 2, 3 Schwertman P.... Marteijn J.A. (2012)
    2. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. (PubMed id 22466612)1, 2, 3 Zhang X.... Tanaka K. (2012)
    3. Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. (PubMed id 22466610)1, 2, 3 Nakazawa Y.... Ogi T. (2012)
    4. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
    5. KIAA1530 protein is recruited by Cockayne syndrome com plementation group protein A (CSA) to participate in transcription-coupled repai r (TCR). (PubMed id 22902626)1 Fei J. and Chen J. (2012)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Joint influence of small-effect genetic variants on h uman longevity. (PubMed id 20834067)1 Yashin A.I....Ukraintseva S.V. (2010)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57654 HGNC: 29304 AceView: KIAA1530 Ensembl:ENSG00000163945 euGenes: HUgn57654
    ECgene: UVSSA H-InvDB: UVSSA

    (According to HUGE)
    About This Section
    HUGE: KIAA1530

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UVSSA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UVSSA gene:
    Search GeneIP for patents involving UVSSA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
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    Sirion Biotech Customized:
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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
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