Aliases for UTS2R Gene
External Ids for UTS2R Gene
Previous HGNC Symbols for UTS2R Gene
Previous GeneCards Identifiers for UTS2R Gene
GeneCards Summary for UTS2R Gene
UTS2R (Urotensin 2 Receptor) is a Protein Coding gene. Diseases associated with UTS2R include Portal Hypertension and Amyotrophic Lateral Sclerosis 3. Among its related pathways are Peptide ligand-binding receptors and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include G-protein coupled receptor activity and urotensin II receptor activity.
UniProtKB/Swiss-Prot for UTS2R Gene
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
The urotensin-II (UT) receptor is a Gq/11-protein-coupled receptor that mediates complex hemodynamic effects and influences neuromuscular physiology. The UT receptor displays greatest expression levels in the peripheral vasculature, heart and kidney.