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UTP6 Gene

protein-coding   GIFtS: 57
GCID: GC17M030187

UTP6, Small Subunit (SSU) Processome Component, Homolog...

(Previous name: chromosome 17 open reading frame 40)
(Previous symbol: C17orf40)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UTP6, Small Subunit (SSU) Processome Component, Homolog (Yeast)1 2     HCA662 3
C17orf401 2 3     Chromosome 17 Open Reading Frame 401
Hepatocellular Carcinoma Associated Antigen 661 2     U3 Small Nucleolar RNA-Associated Protein 6 Homolog2
Hepatocellular Carcinoma-Associated Antigen 662 3     MHAT3
Multiple Hat Domains Protein2 3     

External Ids:    HGNC: 182791   Entrez Gene: 558132   Ensembl: ENSG000001086517   UniProtKB: Q9NYH93   

Export aliases for UTP6 gene to outside databases

Previous GC identifers: GC17M027216 GC17M026401


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UTP6 Gene:
UTP6 (UTP6, small subunit (SSU) processome component, homolog (yeast)) is a protein-coding gene. Diseases associated with UTP6 include hepatocellular carcinoma, and congenital heart defect.

UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9
Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

Gene Wiki entry for UTP6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UTP6 gene promoter:
         NF-1   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUTP6 promoter sequence
   Search Chromatin IP Primers for UTP6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UTP6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

UTP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UTP6 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M030187:  view genomic region     (about GC identifiers)

Start:
30,187,923 bp from pter      End:
30,228,784 bp from pter
Size:
40,862 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9 (See protein sequence)
Recommended Name: U3 small nucleolar RNA-associated protein 6 homolog  
Size: 597 amino acids; 70194 Da
Secondary accessions: Q8IX96 Q96BL2 Q9NQ91

Explore the universe of human proteins at neXtProt for UTP6: NX_Q9NYH9

Explore proteomics data for UTP6 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys180, Lys295, Lys463, Lys479, Lys498, Lys575
  • Modification sites at PhosphoSitePlus

  • See UTP6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060898.2  
    ENSEMBL proteins: 
     ENSP00000261708   ENSP00000462135   ENSP00000464599  

    UTP6 Human Recombinant Protein Products:

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    Cloud-Clone Corp. ELISAs for UTP6
    Cloud-Clone Corp. CLIAs for UTP6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR003107 HAT
     IPR013949 U3_snoRNA_assoc-6

    Graphical View of Domain Structure for InterPro Entry Q9NYH9

    ProtoNet protein and cluster: Q9NYH9

    2 Blocks protein domains:
    IPB003107 RNA-processing protein
    IPB013949 U3 small nucleolar RNA-associated protein 6


    UniProtKB/Swiss-Prot: UTP6_HUMAN, Q9NYH9
    Similarity: Belongs to the UTP6 family
    Similarity: Contains 5 HAT repeats


    UTP6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UTP6_HUMAN, Q9NYH9
    Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

    Phenotypes:
         5 GenomeRNAi human phenotypes for UTP6:

     Decreased nuclei size in G2M  Decreased viability of wild-ty  Increased G2M DNA content  Increased gamma-H2AX phosphory 
     Nucleolar pre-40S maturation d 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UTP6
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UTP6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UTP6

    miRNA
    Products:
        
    miRTarBase miRNAs that target UTP6:
    hsa-let-7b-5p (MIRT032485), hsa-let-7d-5p (MIRT051727), hsa-mir-30a-5p (MIRT028657)

    Block miRNA regulation of human, mouse, rat UTP6 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate UTP6:
    hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidUTP6 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for UTP6
    Predesigned siRNA for gene silencing in human, mouse, rat UTP6

    Gene Editing
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    OriGene ORF clones in mouse, rat for UTP6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UTP6 (NM_018428)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP6

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UTP6_HUMAN, Q9NYH9: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005730nucleolus IDA--

    UTP6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for UTP6 About    
    See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for UTP6):
        Ribosome biogenesis in eukaryotes


    UTP6 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UTP6
    Interactions:

        Search GeneGlobe Interaction Network for UTP6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for UTP6 (Q9NYH92, 3 ENSP000002617084) via UniProtKB, MINT, STRING, and/or I2D (see all 145)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-68353 I2D: score=5 STRING: ENSP00000311695
    RHOXF2Q9BQY42, 3, ENSP000003604414MINT-68193 I2D: score=5 STRING: ENSP00000360441
    KXD1Q9BQD32, 3, ENSP000002223074MINT-67466 I2D: score=4 STRING: ENSP00000222307
    BCL6P411823, ENSP000002320144I2D: score=2 STRING: ENSP00000232014
    NECAB2Q7Z6G33I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--
    GO:0006396RNA processing ----

    UTP6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UTP6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UTP6 gene: 
    NM_018428.2  

    Unigene Cluster for UTP6:

    UTP6, small subunit (SSU) processome component, homolog (yeast)
    Hs.589862  [show with all ESTs]
    Unigene Representative Sequence: AK126564
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261708(uc002hgr.3) ENST00000581012 ENST00000579459 ENST00000477128(uc002hgq.3)
    ENST00000484661 ENST00000477860 ENST00000583408(uc010wbw.1) ENST00000490218
    ENST00000579878
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat UTP6 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate UTP6:
    hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidUTP6 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for UTP6
    Predesigned siRNA for gene silencing in human, mouse, rat UTP6
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UTP6 (NM_018428)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP6
    Primer
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    OriGene qPCR primer pairs and template standards for UTP6
    OriGene qSTAR qPCR primer pairs in human, mouse for UTP6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UTP6
      QuantiTect SYBR Green Assays in human, mouse, rat UTP6
      QuantiFast Probe-based Assays in human, mouse, rat UTP6

    Additional mRNA sequence: 

    AF116631.1 AF244135.1 AF334386.1 AJ272197.1 AK057202.1 AK126564.1 AK225448.1 AK299806.1 
    AK315929.1 BC015454.1 BC035325.1 

    12 DOTS entries:

    DT.207560  DT.101981307  DT.91746371  DT.100824134  DT.100824141  DT.120953784  DT.97817416  DT.120953780 
    DT.70103540  DT.91942184  DT.95140773  DT.99985401 

    Selected AceView cDNA sequences (see all 138):

    NM_018428 F24299 AK057202 BE675092 BM829542 CR625726 BM478186 AW613268 
    AL535002 AI862739 AJ272197 AI805121 CD721821 AW196869 BM905762 BQ938611 
    BC035325 AI924993 AA100219 AI784001 AI949382 BM550227 AL565738 BE876142 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for UTP6 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16a · 16b ^ 17 ^ 18 ^
    SP1:                                                  -                 -                                               -     -                 -               
    SP2:                                                                                                                    -     -                 -               
    SP3:                                      -     -     -     -           -                                                                                       
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                            -               

    ExUns: 19a · 19b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for UTP6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UTP6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTATGCATCA
    UTP6 Expression
    About this image


    UTP6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    UTP6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UTP6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.589862
        Custom PCR Arrays for UTP6
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for UTP6
    OriGene qSTAR qPCR primer pairs in human, mouse for UTP6
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    QuantiTect SYBR Green Assays in human, mouse, rat UTP6
    QuantiFast Probe-based Assays in human, mouse, rat UTP6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for UTP6 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Utp61 , 5 UTP6, small subunit (SSU) processome component, homolog more1, 5 85.35(n)1
    86.24(a)1
      11 (47.29 cM)5
    2169871  NM_144826.31  NP_659075.11 
     799323215 
    chicken
    (Gallus gallus)
    Aves UTP61 UTP6, small subunit (SSU) processome component, homolog more 69.29(n)
    66.19(a)
      417405  NM_001006207.1  NP_001006207.1 
    lizard
    (Anolis carolinensis)
    Reptilia UTP66
    UTP6, small subunit (SSU) processome component, ho...
    65(a)
    1 ↔ 1
    GL343198.1(1406789-1430906)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC539632 hypothetical protein MGC53963 72.97(n)    BC048226.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556482 similar to DSCAM-interacting protein 1 73.84(n)   393107  BC044444.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG72461 CG7246 40.66(n)
    28.8(a)
      31833  NM_132292.4  NP_572520.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP6(YDR449C)4 Nucleolar protein, component of the small subunit (SSU) more   --   4(1358902-1357580) 852060  NP_010737.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G282001 AT4G28200 43.49(n)
    29.95(a)
      828935  NM_118960.2  NP_194549.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01039001 Os02g0103900 43.54(n)
    32.92(a)
      4328001  NM_001052144.1  NP_001045609.1 


    ENSEMBL Gene Tree for UTP6 (if available)
    TreeFam Gene Tree for UTP6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UTP6 gene

    UTP6 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for UTP6
    PGOHUM00000246784 PGOHUM00000233117


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UTP6 (see all 848)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs590477241,2
    C,F--30189871(+) ACAGGC/AGTTGA 1 -- ds50011Minor allele frequency- A:0.13WA 118
    rs7397991,2
    C,F,H--30189950(+) CTTGAC/TCTGGG 1 -- ds500111Minor allele frequency- T:0.01NA MN NS EA 1140
    rs1836175911,2
    --30189964(+) ATTTTA/TAAAAA 1 -- ds50010--------
    rs1887153181,2
    --30189990(+) ATCCAC/TGTATT 1 -- ds50010--------
    rs7398001,2
    C,F,O,A,H--30190083(+) CAAACA/TGAGCA 1 -- ds500123Minor allele frequency- T:0.20MN NS EA NA WA CSA 1183
    rs563669141,2
    C,F--30190090(+) AGCAGT/AGTCAT 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1463538221,2
    --30190211(+) TTTTTA/CATTTT 1 -- ut310--------
    rs169670281,2
    C,F,H--30190348(+) ATACTA/GTTTCA 1 -- ut3118Minor allele frequency- G:0.08NA NS EA WA EU 3681
    rs1996559911,2
    --30190458(+) CGCTCA/GCCAGT 2 R * stg10--------
    rs2017625671,2
    --30190475(+) GTCCAC/TAGTTC 2 Y C mis10--------

    HapMap Linkage Disequilibrium report for UTP6 (30187923 - 30228784 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for UTP6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908065CNV Loss21882294
    dgv944e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UTP6
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    8 diseases for UTP6:    
    About MalaCards
    hepatocellular carcinoma    congenital heart defect    neurofibromatosis    tonsillitis
    hiv-1    malaria    cerebritis    endotheliitis


    UTP6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): UTP6

    Export disorders for UTP6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UTP6 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with UTP6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. (PubMed id 10843809)1, 2, 3 Jenne D.E.... Thiel G. (Genomics 2000)
    2. Evidence by expression analysis of candidate genes for congenital heart defects in the NF1 microdeletion interval. (PubMed id 16138909)1, 3 Venturin M....Riva P. (Ann. Hum. Genet. 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    5. Large scale identification of human hepatocellular carcinoma- associated antigens by autoantibodies. (PubMed id 12097419)1, 2 Wang Y....Chen W.-F. (J. Immunol. 2002)
    6. Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients. (PubMed id 17380155)1, 9 Piddubnyak V....Poyet J.L. (Cell Death Differ. 2007)
    7. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55813 HGNC: 18279 AceView: HCA66 Ensembl:ENSG00000108651 euGenes: HUgn55813
    ECgene: UTP6 Kegg: 55813 H-InvDB: UTP6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UTP6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UTP6 gene:
    Search GeneIP for patents involving UTP6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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