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Aliases for UTP3 Gene

Aliases for UTP3 Gene

  • UTP3, Small Subunit (SSU) Processome Component, Homolog (S. Cerevisiae) 2 3
  • CRLZ1 3 4 6
  • CRL1 3 4 6
  • Charged Amino Acid-Rich Leucine Zipper 1 3 4
  • Disrupter Of Silencing SAS10 3 4
  • Disrupter Of Silencing 10 2 3
  • UTP3 Homolog 3 4
  • SAS10 3 4
  • Charged Amino Acid Rich Leucine Zipper 1 Homolog 3
  • Something About Silencing Protein 10 3

External Ids for UTP3 Gene

Previous GeneCards Identifiers for UTP3 Gene

  • GC04P071775
  • GC04P071554
  • GC04P067358

Summaries for UTP3 Gene

GeneCards Summary for UTP3 Gene

UTP3 (UTP3, Small Subunit (SSU) Processome Component, Homolog (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with UTP3 include choledocholithiasis.

UniProtKB/Swiss-Prot for UTP3 Gene

  • Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity).

Gene Wiki entry for UTP3 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP3 Gene

Genomics for UTP3 Gene

Regulatory Elements for UTP3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for UTP3 Gene

Start:
70,688,479 bp from pter
End:
70,690,551 bp from pter
Size:
2,073 bases
Orientation:
Plus strand

Genomic View for UTP3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UTP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP3 Gene

Proteins for UTP3 Gene

  • Protein details for UTP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQZ2-SAS10_HUMAN
    Recommended name:
    Something about silencing protein 10
    Protein Accession:
    Q9NQZ2
    Secondary Accessions:
    • Q6FI82

    Protein attributes for UTP3 Gene

    Size:
    479 amino acids
    Molecular mass:
    54558 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UTP3 Gene

Proteomics data for UTP3 Gene at MOPED

Post-translational modifications for UTP3 Gene

Other Protein References for UTP3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UTP3 Gene

Domains for UTP3 Gene

Protein Domains for UTP3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for UTP3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NQZ2

UniProtKB/Swiss-Prot:

SAS10_HUMAN :
  • Q9NQZ2
Family:
  • Belongs to the SAS10 family.
genes like me logo Genes that share domains with UTP3: view

No data available for Gene Families for UTP3 Gene

Function for UTP3 Gene

Molecular function for UTP3 Gene

UniProtKB/Swiss-Prot Function: Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity).

Gene Ontology (GO) - Molecular Function for UTP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with UTP3: view
genes like me logo Genes that share phenotypes with UTP3: view

Animal Model Products

CRISPR Products

miRNA for UTP3 Gene

miRTarBase miRNAs that target UTP3

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UTP3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for UTP3 Gene

Localization for UTP3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UTP3 Gene COMPARTMENTS Subcellular localization image for UTP3 gene
Compartment Confidence
nucleus 4
mitochondrion 2
cytosol 1

Gene Ontology (GO) - Cellular Components for UTP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005730 nucleolus IDA --
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with UTP3: view

Pathways for UTP3 Gene

SuperPathways for UTP3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for UTP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA --
GO:0007420 brain development ISS --
GO:0016568 chromatin modification IEA --
genes like me logo Genes that share ontologies with UTP3: view

No data available for Pathways by source for UTP3 Gene

Transcripts for UTP3 Gene

mRNA/cDNA for UTP3 Gene

(126) Selected AceView cDNA sequences:
(5) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for UTP3 Gene

UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UTP3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UTP3 Gene

No ASD Table

Relevant External Links for UTP3 Gene

GeneLoc Exon Structure for
UTP3
ECgene alternative splicing isoforms for
UTP3

Expression for UTP3 Gene

mRNA expression in normal human tissues for UTP3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UTP3 Gene

SOURCE GeneReport for Unigene cluster for UTP3 Gene Hs.322901

genes like me logo Genes that share expressions with UTP3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UTP3 Gene

Orthologs for UTP3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UTP3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UTP3 35
  • 99.65 (n)
  • 99.58 (a)
UTP3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UTP3 35
  • 88.06 (n)
  • 88.14 (a)
UTP3 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UTP3 35
  • 87.18 (n)
  • 87.82 (a)
UTP3 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Utp3 35
  • 82.87 (n)
  • 84.86 (a)
Utp3 16
Utp3 36
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UTP3 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UTP3 36
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Utp3 35
  • 82.41 (n)
  • 84.04 (a)
chicken
(Gallus gallus)
Aves UTP3 35
  • 60.36 (n)
  • 55.01 (a)
UTP3 36
  • 51 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UTP3 36
  • 53 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.2574 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7619 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5012 35
zebrafish
(Danio rerio)
Actinopterygii Dr.17306 35
utp3 35
  • 57.06 (n)
  • 53.4 (a)
utp3 36
  • 48 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002960 35
  • 46.7 (n)
  • 36.1 (a)
fruit fly
(Drosophila melanogaster)
Insecta Sas10 35
  • 47.48 (n)
  • 42.73 (a)
Sas10 36
  • 38 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SAS10 36
  • 20 (a)
OneToOne
SAS10 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5711 36
  • 34 (a)
OneToOne
Species with no ortholog for UTP3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UTP3 Gene

ENSEMBL:
Gene Tree for UTP3 (if available)
TreeFam:
Gene Tree for UTP3 (if available)

Paralogs for UTP3 Gene

No data available for Paralogs for UTP3 Gene

Variants for UTP3 Gene

Sequence variations from dbSNP and Humsavar for UTP3 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs3733488 -- 70,688,558(-) CACCG(A/G)AGTTT utr-variant-5-prime
rs11541969 -- 70,689,610(+) AAGCT(C/G)TCCGT synonymous-codon, reference
rs16845380 -- 70,686,588(+) TCTTA(C/T)CCTTC upstream-variant-2KB
rs16845383 -- 70,686,681(+) TATAC(A/G)GTCCT upstream-variant-2KB
rs16845385 - 70,688,745(+) TCCCA(C/T)GCTCA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for UTP3 Gene

Variant ID Type Subtype PubMed ID
nsv829965 CNV Gain 17160897

Relevant External Links for UTP3 Gene

HapMap Linkage Disequilibrium report
UTP3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UTP3 Gene

Disorders for UTP3 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for UTP3 Gene including...

Search for UTP3 Gene in MalaCards »

(2) University of Copenhagen DISEASES for UTP3 Gene

genes like me logo Genes that share disorders with UTP3: view

No data available for UniProtKB/Swiss-Prot for UTP3 Gene

Publications for UTP3 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4

Products for UTP3 Gene

Sources for UTP3 Gene

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