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Aliases for UTP23 Gene

Aliases for UTP23 Gene

  • UTP23, Small Subunit (SSU) Processome Component, Homolog (Yeast) 2 3
  • C8orf53 3 4
  • RRNA-Processing Protein UTP23 Homolog 3
  • Chromosome 8 Open Reading Frame 53 2

External Ids for UTP23 Gene

Previous HGNC Symbols for UTP23 Gene

  • C8orf53

Previous GeneCards Identifiers for UTP23 Gene

  • GC08P117849
  • GC08P113105

Summaries for UTP23 Gene

GeneCards Summary for UTP23 Gene

UTP23 (UTP23, Small Subunit (SSU) Processome Component, Homolog (Yeast)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for UTP23 Gene

  • Involved in rRNA-processing and ribosome biogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP23 Gene

Genomics for UTP23 Gene

Regulatory Elements for UTP23 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for UTP23 Gene

116,766,503 bp from pter
116,849,463 bp from pter
82,961 bases
Plus strand

Genomic View for UTP23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UTP23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP23 Gene

Proteins for UTP23 Gene

  • Protein details for UTP23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    rRNA-processing protein UTP23 homolog
    Protein Accession:
    Secondary Accessions:
    • B2RE25
    • Q96NJ8

    Protein attributes for UTP23 Gene

    249 amino acids
    Molecular mass:
    28402 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for UTP23 Gene


neXtProt entry for UTP23 Gene

Proteomics data for UTP23 Gene at MOPED

Post-translational modifications for UTP23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UTP23 Gene

Antibody Products

No data available for DME Specific Peptides for UTP23 Gene

Domains for UTP23 Gene

Protein Domains for UTP23 Gene


Suggested Antigen Peptide Sequences for UTP23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UTP23/FCF1 family. UTP23 subfamily.
  • Belongs to the UTP23/FCF1 family. UTP23 subfamily.
genes like me logo Genes that share domains with UTP23: view

No data available for Gene Families for UTP23 Gene

Function for UTP23 Gene

Molecular function for UTP23 Gene

UniProtKB/Swiss-Prot Function:
Involved in rRNA-processing and ribosome biogenesis.

Gene Ontology (GO) - Molecular Function for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0070181 small ribosomal subunit rRNA binding IBA --
genes like me logo Genes that share ontologies with UTP23: view

Animal Model Products

CRISPR Products

miRNA for UTP23 Gene

miRTarBase miRNAs that target UTP23

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for UTP23 Gene

Localization for UTP23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP23 Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for UTP23 Gene COMPARTMENTS Subcellular localization image for UTP23 gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IBA --
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with UTP23: view

Pathways for UTP23 Gene

SuperPathways for UTP23 Gene

No Data Available

Gene Ontology (GO) - Biological Process for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA --
GO:0006364 rRNA processing --
genes like me logo Genes that share ontologies with UTP23: view

No data available for Pathways by source for UTP23 Gene

Transcripts for UTP23 Gene

Unigene Clusters for UTP23 Gene

UTP23, small subunit (SSU) processome component, homolog (yeast):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UTP23 Gene

No ASD Table

Relevant External Links for UTP23 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for UTP23 Gene

mRNA expression in normal human tissues for UTP23 Gene

Protein differential expression in normal tissues for UTP23 Gene

This gene is overexpressed in Lung (34.3), Peripheral blood mononuclear cells (14.6), and CD8 Tcells (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UTP23 Gene

SOURCE GeneReport for Unigene cluster for UTP23 Gene Hs.86970

genes like me logo Genes that share expressions with UTP23: view

Expression partners for UTP23 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UTP23 Gene

Orthologs for UTP23 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP23 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC781182 35
  • 90.86 (n)
  • 92.34 (a)
UTP23 36
  • 92 (a)
(Canis familiaris)
Mammalia UTP23 35
  • 93.52 (n)
  • 94.33 (a)
UTP23 36
  • 94 (a)
(Mus musculus)
Mammalia Utp23 35
  • 83.74 (n)
  • 87.5 (a)
Utp23 16
Utp23 36
  • 86 (a)
(Pan troglodytes)
Mammalia UTP23 35
  • 99.33 (n)
  • 99.2 (a)
UTP23 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Utp23 35
  • 83.67 (n)
  • 87.85 (a)
(Monodelphis domestica)
Mammalia UTP23 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia UTP23 36
  • 59 (a)
(Gallus gallus)
Aves UTP23 35
  • 72.12 (n)
  • 69.55 (a)
UTP23 36
  • 66 (a)
(Anolis carolinensis)
Reptilia UTP23 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6335 35
utp23 35
  • 69.38 (n)
  • 71.04 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.23930 35
(Danio rerio)
Actinopterygii utp23 35
  • 62.54 (n)
  • 61.47 (a)
utp23 36
  • 56 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2232 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008325 35
  • 49.69 (n)
  • 41.67 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17652 35
  • 47.44 (n)
  • 41.83 (a)
CG17652 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea C34E10.10 35
  • 50.58 (n)
  • 43.78 (a)
C34E10.10 36
  • 38 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ACR011C 35
  • 41.49 (n)
  • 32.91 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D01023g 35
  • 44.04 (n)
  • 31.65 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP23 35
  • 42.42 (n)
  • 33.01 (a)
UTP23 36
  • 30 (a)
UTP23 38
thale cress
(Arabidopsis thaliana)
eudicotyledons MEE21 35
  • 49 (n)
  • 36.87 (a)
(Oryza sativa)
Liliopsida Os02g0468200 35
  • 49.54 (n)
  • 37.16 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02748 35
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes utp23 35
  • 40.69 (n)
  • 34.74 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10877 36
  • 43 (a)
Species with no ortholog for UTP23:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP23 Gene

Gene Tree for UTP23 (if available)
Gene Tree for UTP23 (if available)

Paralogs for UTP23 Gene

(1) SIMAP similar genes for UTP23 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with UTP23: view

No data available for Paralogs for UTP23 Gene

Variants for UTP23 Gene

Sequence variations from dbSNP and Humsavar for UTP23 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs921066 -- 116,779,977(-) GAAAA(A/T)CCCAG utr-variant-3-prime
rs979866 -- 116,779,494(-) AAGCT(A/G)GCAGA synonymous-codon, reference
rs979867 -- 116,779,263(-) TATGC(C/T)TACTG intron-variant
rs1051490 -- 116,774,418(+) GCTAG(G/T)TTTTT utr-variant-3-prime, intron-variant
rs1133950 - 116,771,675(-) GCGCT(G/T)TTTTC reference, missense, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UTP23 Gene

Variant ID Type Subtype PubMed ID
nsv824724 CNV Loss 20364138
nsv831434 CNV Gain 17160897

Relevant External Links for UTP23 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UTP23 Gene

Disorders for UTP23 Gene

No disorders were found for UTP23 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for UTP23 Gene

Publications for UTP23 Gene

  1. The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. (PMID: 16769905) Bleichert F. … Baserga S.J. (Proc. Natl. Acad. Sci. U.S.A. 2006) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for UTP23 Gene

Sources for UTP23 Gene

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