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Aliases for UTP23 Gene

Aliases for UTP23 Gene

  • UTP23, Small Subunit (SSU) Processome Component, Homolog (Yeast) 2 3
  • C8orf53 3 4
  • RRNA-Processing Protein UTP23 Homolog 3
  • Chromosome 8 Open Reading Frame 53 2

External Ids for UTP23 Gene

Previous Symbols for UTP23 Gene

  • C8orf53

Summaries for UTP23 Gene

GeneCards Summary for UTP23 Gene

UTP23 (UTP23, Small Subunit (SSU) Processome Component, Homolog (Yeast)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for UTP23 Gene

  • Involved in rRNA-processing and ribosome biogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP23 Gene

Genomics for UTP23 Gene

Genomic Location for UTP23 Gene

Start:
116,766,503 bp from pter
End:
116,849,463 bp from pter
Size:
82,961 bases
Orientation:
Plus strand

Genomic View for UTP23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UTP23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP23 Gene

Regulatory Elements for UTP23 Gene

Proteins for UTP23 Gene

  • Protein details for UTP23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BRU9-UTP23_HUMAN
    Recommended name:
    rRNA-processing protein UTP23 homolog
    Protein Accession:
    Q9BRU9
    Secondary Accessions:
    • B2RE25
    • Q96NJ8

    Protein attributes for UTP23 Gene

    Size:
    249 amino acids
    Molecular mass:
    28402 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for UTP23 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UTP23 Gene

Proteomics data for UTP23 Gene at MOPED

Post-translational modifications for UTP23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UTP23 Gene

No data available for DME Specific Peptides for UTP23 Gene

Domains for UTP23 Gene

Protein Domains for UTP23 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

UTP23_HUMAN
Family:
  • Belongs to the UTP23/FCF1 family. UTP23 subfamily.:
    • Q9BRU9
genes like me logo Genes that share domains with UTP23: view

No data available for Gene Families for UTP23 Gene

Function for UTP23 Gene

Molecular function for UTP23 Gene

UniProtKB/Swiss-Prot Function: Involved in rRNA-processing and ribosome biogenesis.

Gene Ontology (GO) - Molecular Function for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22658674
GO:0070181 small ribosomal subunit rRNA binding IBA --
genes like me logo Genes that share ontologies with UTP23: view

miRNA for UTP23 Gene

miRTarBase miRNAs that target UTP23

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for UTP23 Gene

Localization for UTP23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP23 Gene

Nucleus, nucleolus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UTP23 Gene COMPARTMENTS Subcellular localization image for UTP23 gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IBA --
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with UTP23: view

Pathways for UTP23 Gene

SuperPathways for UTP23 Gene

No Data Available

Gene Ontology (GO) - Biological Process for UTP23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA --
GO:0006364 rRNA processing --
genes like me logo Genes that share ontologies with UTP23: view

No data available for Pathways by source for UTP23 Gene

Transcripts for UTP23 Gene

Unigene Clusters for UTP23 Gene

UTP23, small subunit (SSU) processome component, homolog (yeast):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UTP23 Gene

No ASD Table

Relevant External Links for UTP23 Gene

GeneLoc Exon Structure for
UTP23
ECgene alternative splicing isoforms for
UTP23

Expression for UTP23 Gene

mRNA expression in normal human tissues for UTP23 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UTP23 Gene

SOURCE GeneReport for Unigene cluster for UTP23 Gene Hs.86970

genes like me logo Genes that share expressions with UTP23: view

Orthologs for UTP23 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP23 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UTP23 36
  • 99.33 (n)
  • 99.2 (a)
UTP23 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC781182 36
  • 90.86 (n)
  • 92.34 (a)
UTP23 37
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UTP23 36
  • 93.52 (n)
  • 94.33 (a)
UTP23 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Utp23 36
  • 83.74 (n)
  • 87.5 (a)
Utp23 16
Utp23 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UTP23 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UTP23 37
  • 59 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Utp23 36
  • 83.67 (n)
  • 87.85 (a)
chicken
(Gallus gallus)
Aves UTP23 36
  • 72.12 (n)
  • 69.55 (a)
UTP23 37
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UTP23 37
  • 63 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.23930 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.6335 36
utp23 36
  • 69.38 (n)
  • 71.04 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2232 36
zebrafish
(Danio rerio)
Actinopterygii utp23 36
  • 62.54 (n)
  • 61.47 (a)
utp23 37
  • 56 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008325 36
  • 49.69 (n)
  • 41.67 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17652 36
  • 47.44 (n)
  • 41.83 (a)
CG17652 37
  • 39 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C34E10.10 36
  • 50.58 (n)
  • 43.78 (a)
C34E10.10 37
  • 38 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ACR011C 36
  • 41.49 (n)
  • 32.91 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP23 36
  • 42.42 (n)
  • 33.01 (a)
UTP23 37
  • 30 (a)
OneToOne
UTP23 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D01023g 36
  • 44.04 (n)
  • 31.65 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons MEE21 36
  • 49 (n)
  • 36.87 (a)
rice
(Oryza sativa)
Liliopsida Os02g0468200 36
  • 49.54 (n)
  • 37.16 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU02748 36
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes utp23 36
  • 40.69 (n)
  • 34.74 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10877 37
  • 43 (a)
OneToOne
Species with no ortholog for UTP23:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP23 Gene

ENSEMBL:
Gene Tree for UTP23 (if available)
TreeFam:
Gene Tree for UTP23 (if available)

Paralogs for UTP23 Gene

Selected SIMAP similar genes for UTP23 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with UTP23: view

No data available for Paralogs for UTP23 Gene

Variants for UTP23 Gene

Sequence variations from dbSNP and Humsavar for UTP23 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs921066 -- 116,779,977(-) GAAAA(A/T)CCCAG utr-variant-3-prime
rs979866 -- 116,779,494(-) AAGCT(A/G)GCAGA synonymous-codon, reference
rs979867 -- 116,779,263(-) TATGC(C/T)TACTG intron-variant
rs1051490 -- 116,774,418(+) GCTAG(G/T)TTTTT utr-variant-3-prime, intron-variant
rs1133950 - 116,771,675(-) GCGCT(G/T)TTTTC reference, missense, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UTP23 Gene

Variant ID Type Subtype PubMed ID
nsv824724 CNV Loss 20364138
nsv831434 CNV Gain 17160897

Relevant External Links for UTP23 Gene

HapMap Linkage Disequilibrium report
UTP23

Disorders for UTP23 Gene

No disorders were found for UTP23 Gene.

No data available for UniProtKB/Swiss-Prot for UTP23 Gene

Publications for UTP23 Gene

  1. The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. (PMID: 16769905) Bleichert F. … Baserga S.J. (Proc. Natl. Acad. Sci. U.S.A. 2006) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for UTP23 Gene

Sources for UTP23 Gene

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