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UTP23 Gene

protein-coding   GIFtS: 48
GCID: GC08P117849

UTP23, Small Subunit (SSU) Processome Component, Homolog...

(Previous name: chromosome 8 open reading frame 53)
(Previous symbol: C8orf53)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UTP23, Small Subunit (SSU) Processome Component, Homolog (Yeast)1 2
C8orf531 2 3
Chromosome 8 Open Reading Frame 531
RRNA-Processing Protein UTP23 Homolog2

External Ids:    HGNC: 282241   Entrez Gene: 842942   Ensembl: ENSG000001476797   UniProtKB: Q9BRU93   

Export aliases for UTP23 gene to outside databases

Previous GC identifer: GC08P113105


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UTP23 Gene:
UTP23 (UTP23, small subunit (SSU) processome component, homolog (yeast)) is a protein-coding gene. Diseases associated with UTP23 include malaria.

UniProtKB/Swiss-Prot: UTP23_HUMAN, Q9BRU9
Function: Involved in rRNA-processing and ribosome biogenesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UTP23 gene promoter:
         HFH-3   Max1   Sox5   Sp1   MyoD   C/EBPalpha   MEF-2A   FOXI1   aMEF-2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUTP23 promoter sequence
   Search Chromatin IP Primers for UTP23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UTP23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.11   Ensembl cytogenetic band:  8q24.11   HGNC cytogenetic band: 8q24.11

UTP23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UTP23 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P117849:  view genomic region     (about GC identifiers)

Start:
117,778,742 bp from pter      End:
117,861,702 bp from pter
Size:
82,961 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: UTP23_HUMAN, Q9BRU9 (See protein sequence)
Recommended Name: rRNA-processing protein UTP23 homolog  
Size: 249 amino acids; 28402 Da
Secondary accessions: B2RE25 Q96NJ8
Alternative splicing: 2 isoforms:  Q9BRU9-1   Q9BRU9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UTP23: NX_Q9BRU9

Explore proteomics data for UTP23 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See UTP23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115710.2  
    ENSEMBL proteins: 
     ENSP00000308332   ENSP00000428455   ENSP00000429962   ENSP00000430029   ENSP00000427767  
     ENSP00000429384   ENSP00000430309   ENSP00000349670  

    UTP23 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for UTP23
    OriGene Custom MassSpec
    OriGene Custom Protein Services for UTP23
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    Novus Biologicals UTP23 Protein
    Novus Biologicals UTP23 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for UTP23
    Cloud-Clone Corp. Proteins for UTP23

    UTP23 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals UTP23 Antibodies
    Abcam antibodies for UTP23
    Cloud-Clone Corp. Antibodies for UTP23
    ThermoFisher Antibodies for UTP23
    LSBio Antibodies in human, mouse, rat for UTP23

    UTP23 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for UTP23
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for UTP23
    Cloud-Clone Corp. CLIAs for UTP23


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006984 Fcf1/Utp23

    Graphical View of Domain Structure for InterPro Entry Q9BRU9

    ProtoNet protein and cluster: Q9BRU9

    UniProtKB/Swiss-Prot: UTP23_HUMAN, Q9BRU9
    Similarity: Belongs to the UTP23/FCF1 family. UTP23 subfamily


    UTP23 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UTP23_HUMAN, Q9BRU9
    Function: Involved in rRNA-processing and ribosome biogenesis (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    UTP23 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UTP23
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UTP23
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UTP23

    miRNA
    Products:
        
    miRTarBase miRNAs that target UTP23:
    hsa-mir-16-5p (MIRT031537)

    Block miRNA regulation of human, mouse, rat UTP23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UTP23 (see all 11):
    hsa-miR-3618 hsa-miR-579 hsa-miR-520d-5p hsa-miR-130a* hsa-miR-23c hsa-miR-548l hsa-miR-146a* hsa-miR-23b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for UTP23
    Predesigned siRNA for gene silencing in human, mouse, rat UTP23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for UTP23

    Clone
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    OriGene clones in human, mouse for UTP23 (see all 7)
    OriGene ORF clones in mouse, rat for UTP23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UTP23 (NM_032334)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP23

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for UTP23 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UTP23_HUMAN, Q9BRU9: Nucleus, nucleolus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0032040small-subunit processome IEA--

    UTP23 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UTP23
    Interactions:

        Search GeneGlobe Interaction Network for UTP23

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for UTP23 (Q9BRU93 ENSP000003083324) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DCTN5Q9BTE13I2D: score=1 
    KRTAP4-12Q9BQ663I2D: score=1 
    DCAF13ENSP000002975794STRING: ENSP00000297579
    NOP58ENSP000002642794STRING: ENSP00000264279
    DKC1ENSP000003585634STRING: ENSP00000358563
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--

    UTP23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UTP23



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UTP23 gene: 
    NM_032334.2  

    Unigene Cluster for UTP23:

    UTP23, small subunit (SSU) processome component, homolog (yeast)
    Hs.86970  [show with all ESTs]
    Unigene Representative Sequence: NM_032334
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000309822(uc003yoc.3) ENST00000521703 ENST00000517814 ENST00000521071
    ENST00000519443 ENST00000517820 ENST00000521974 ENST00000520733 ENST00000524128
    ENST00000357148
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat UTP23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UTP23 (see all 11):
    hsa-miR-3618 hsa-miR-579 hsa-miR-520d-5p hsa-miR-130a* hsa-miR-23c hsa-miR-548l hsa-miR-146a* hsa-miR-23b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for UTP23
    Predesigned siRNA for gene silencing in human, mouse, rat UTP23
    Clone
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    OriGene clones in human, mouse for UTP23 (see all 7)
    OriGene ORF clones in mouse, rat for UTP23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UTP23 (NM_032334)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP23
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for UTP23
    OriGene qSTAR qPCR primer pairs in human, mouse for UTP23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UTP23
      QuantiTect SYBR Green Assays in human, mouse, rat UTP23
      QuantiFast Probe-based Assays in human, mouse, rat UTP23

    Additional mRNA sequence: 

    AK315770.1 BC005955.1 BC022441.1 

    21 DOTS entries:

    DT.440334  DT.121468877  DT.99951983  DT.97824087  DT.100775845  DT.100001297  DT.121468830  DT.91715239 
    DT.209021  DT.92022825  DT.97790792  DT.100778712  DT.452774  DT.95318862  DT.100670857  DT.100715646 
    DT.101957256  DT.40252179  DT.75191889  DT.91872784  DT.91952378 

    Selected AceView cDNA sequences (see all 130):

    BX476762 BX483613 BQ897640 BQ680542 CR625411 AI301401 BQ683666 BU167853 
    CD365234 BQ680911 BM931198 AA767509 BQ186975 AA056028 AI373246 BE018632 
    BQ679942 BU179334 BF001846 BQ683436 AI056895 CK300049 CB321992 AI033700 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UTP23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAAAGAAAG
    UTP23 Expression
    About this image

    UTP23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UTP23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.86970
        Custom PCR Arrays for UTP23
    Primer
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    OriGene qPCR primer pairs and template standards for UTP23
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    QuantiFast Probe-based Assays in human, mouse, rat UTP23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for UTP23 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Utp231 , 5 UTP23, small subunit (SSU) processome component, homolog more1, 5 83.74(n)1
    87.5(a)1
      15 (19.49 cM)5
    785811  NM_030132.51  NP_084408.11 
     518774295 
    chicken
    (Gallus gallus)
    Aves UTP231 UTP23, small subunit (SSU) processome component, homolog more 72.12(n)
    69.55(a)
      420287  XM_418400.4  XP_418400.1 
    lizard
    (Anolis carolinensis)
    Reptilia UTP236
    UTP23, small subunit (SSU) processome component, h...
    63(a)
    1 ↔ 1
    4(7082438-7095660)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.239302 Xenopus laevis transcribed sequence with weak similarity more 74.48(n)    48017860 
    zebrafish
    (Danio rerio)
    Actinopterygii BI888437.12   -- 76.43(n)    BI888437.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG176521 CG17652 47.44(n)
    41.83(a)
      33353  NM_134773.2  NP_608617.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C34E10.101 C34E10.10 50.58(n)
    43.78(a)
      175715  NM_065709.4  NP_498110.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP23(YOR004W)4
    UTP231
    Essential nucleolar protein that is a component of more4
    UTP231
    42.42(n)1
    33.01(a)1
      15(333592-334356)4
    8541651, 4  NP_014646.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons MEE211 MEE21 49(n)
    36.87(a)
      818021  NM_129010.4  NP_181004.2 
    rice
    (Oryza sativa)
    Liliopsida Os02g04682001 Os02g0468200 49.54(n)
    37.16(a)
      4329331  NM_001053356.1  NP_001046821.1 


    ENSEMBL Gene Tree for UTP23 (if available)
    TreeFam Gene Tree for UTP23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UTP23 gene
    1 SIMAP similar gene for UTP23 using alignment to 7 protein entries:     UTP23_HUMAN (see all proteins):
    FCF1

    UTP23 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UTP23 (see all 205)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1181110581,2
    F--117776830(+) CATTTT/GAAACA 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1840816081,2
    --117776916(+) TTTTCC/TCTTTT 1 -- us2k10--------
    rs70002331,2
    H--117776924(+) TTTTGT/ACTTCT 1 -- us2k14Minor allele frequency- A:0.00NS EA 410
    rs1884157081,2
    --117777309(+) AAAAAC/TGTTTT 1 -- us2k10--------
    rs1171656891,2
    C,F--117777361(+) TGTGGT/CGGGCG 1 -- us2k11Minor allele frequency- C:0.07EA 120
    rs1927448291,2
    --117777534(+) TGATGG/TGCTGG 1 -- us2k10--------
    rs38124621,2
    H--117777572(-) TTGGAA/GTAAGA 1 -- us2k14Minor allele frequency- G:0.00NS EA 416
    rs1841922791,2
    --117777764(+) AGTGGA/GTACTC 1 -- us2k10--------
    rs1393637431,2
    --117777877(+) GTTACC/TGGCCC 1 -- us2k10--------
    rs48766801,2
    C,F,A,H--117777914(+) CCATGG/CACATA 1 -- us2k121Minor allele frequency- C:0.43NA EA WA CSA 883

    HapMap Linkage Disequilibrium report for UTP23 (117778742 - 117861702 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for UTP23:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv824724CNV Loss20364138
    nsv831434CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UTP23
    DNA2.0 Custom Variant and Variant Library Synthesis for UTP23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for UTP23:    About MalaCards
    malaria


    UTP23 for disorders           About GeneDecksing


    Export disorders for UTP23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UTP23 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with UTP23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. (PubMed id 16769905)1, 3 Bleichert F....Baserga S.J. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (Nature 2006)
    8. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84294 HGNC: 28224 AceView: MGC14595 Ensembl:ENSG00000147679 euGenes: HUgn84294
    ECgene: UTP23 H-InvDB: UTP23

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UTP23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UTP23 gene:
    Search GeneIP for patents involving UTP23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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