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UTP18 Gene

protein-coding   GIFtS: 48
GCID: GC17P049337

UTP18 Small Subunit (SSU) Processome Component Homolog (Yeast)

(Previous name: WD repeat domain 50)
(Previous symbol: WDR50)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UTP18 Small Subunit (SSU) Processome Component Homolog (Yeast)1 2     CGI-482
WDR501 2 3     U3 Small Nucleolar RNA-Associated Protein 18 Homolog2
WD Repeat Domain 501 2     UTP18, Small Subunit (SSU) Processome Component, Homolog2
WD Repeat-Containing Protein 502 3     

External Ids:    HGNC: 242741   Entrez Gene: 510962   Ensembl: ENSG000000112607   OMIM: 6128165   UniProtKB: Q9Y5J13   

Export aliases for UTP18 gene to outside databases

Previous GC identifers: GC17P046694 GC17P044707


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UTP18 Gene:
UTP18 (UTP18 small subunit (SSU) processome component homolog (yeast)) is a protein-coding gene.

UniProtKB/Swiss-Prot: UTP18_HUMAN, Q9Y5J1
Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

Gene Wiki entry for UTP18 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the UTP18 gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   POU2F2   RORalpha2   POU2F2C   NRF-2   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUTP18 promoter sequence
   Search Chromatin IP Primers for UTP18

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UTP18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

UTP18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UTP18 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P049337:  view genomic region     (about GC identifiers)

Start:
49,337,889 bp from pter      End:
49,375,297 bp from pter
Size:
37,409 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: UTP18_HUMAN, Q9Y5J1 (See protein sequence)
Recommended Name: U3 small nucleolar RNA-associated protein 18 homolog  
Size: 556 amino acids; 62004 Da
Sequence caution: Sequence=AAD34043.1; Type=Frameshift; Positions=19; Sequence=AAG01999.1; Type=Erroneous
initiation;
Secondary accessions: Q9H4N6

Explore the universe of human proteins at neXtProt for UTP18: NX_Q9Y5J1

Explore proteomics data for UTP18 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys287, Lys329, Lys519
  • Modification sites at PhosphoSitePlus

  • See UTP18 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057085.2  
    ENSEMBL proteins: 
     ENSP00000225298   ENSP00000441335   ENSP00000462614   ENSP00000464095   ENSP00000464194  
     ENSP00000463499  

    UTP18 Human Recombinant Protein Products:

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    Novus Biologicals UTP18 Protein
    Novus Biologicals UTP18 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UTP18

     
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    antibodies-online proteins for UTP18 (4 products) 

     
    antibodies-online peptides for UTP18

    UTP18 Antibody Products:

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    ThermoFisher Antibody for UTP18
    antibodies-online antibodies for UTP18 (10 products) 

    UTP18 Assay Products:

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    Cloud-Clone Corp. ELISAs for UTP18
    Cloud-Clone Corp. CLIAs for UTP18
    Search eBioscience for ELISAs for UTP18 
    antibodies-online kits for UTP18 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    WDR: WD repeat domain containing

    5 InterPro protein domains:
     IPR019775 WD40_repeat_CS
     IPR024977 Apc4_WD40_dom
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y5J1

    ProtoNet protein and cluster: Q9Y5J1

    UniProtKB/Swiss-Prot: UTP18_HUMAN, Q9Y5J1
    Similarity: Belongs to the WD repeat UTP18 family
    Similarity: Contains 6 WD repeats


    Find genes that share domains with UTP18           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UTP18_HUMAN, Q9Y5J1
    Function: Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with UTP18           About GenesLikeMe


    Phenotypes:
         6 GenomeRNAi human phenotypes for UTP18:
     Decreased cell number  Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Nuclear 40S maturation defects 
     Nucleolar pre-40S maturation d  Wnt reporter downregulated 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for UTP18

    miRNA
    Products:
        
    miRTarBase miRNAs that target UTP18:
    hsa-mir-877-3p (MIRT037059)

    Block miRNA regulation of human, mouse, rat UTP18 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate UTP18:
    hsa-miR-499-5p hsa-miR-656 hsa-miR-208a hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidUTP18 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for UTP18
    Predesigned siRNA for gene silencing in human, mouse, rat UTP18

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: UTP18 (NM_016001)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP18
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP18

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for UTP18 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP18


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UTP18_HUMAN, Q9Y5J1: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    Find genes that share ontologies with UTP18           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for UTP18 About    
    See pathways by source

    SuperPathContained pathways About
    1Ribosome biogenesis in eukaryotes
    Ribosome biogenesis in eukaryotes


    Find genes that share SuperPaths with UTP18           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for UTP18):
        Ribosome biogenesis in eukaryotes

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UTP18
    Interactions:

        Search GeneGlobe Interaction Network for UTP18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for UTP18 (Q9Y5J13 ENSP000002252984) via UniProtKB, MINT, STRING, and/or I2D (see all 111)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--

    Find genes that share ontologies with UTP18           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UTP18



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for UTP18 gene: 
    NM_016001.2  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000225298(uc002its.3) ENST00000508506 ENST00000583725 ENST00000583205
    ENST00000579261 ENST00000582832 ENST00000582150
    miRNA
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    Block miRNA regulation of human, mouse, rat UTP18 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate UTP18:
    hsa-miR-499-5p hsa-miR-656 hsa-miR-208a hsa-miR-208b
    SwitchGear 3'UTR luciferase reporter plasmidUTP18 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for UTP18
    Predesigned siRNA for gene silencing in human, mouse, rat UTP18
    Clone
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    GenScript: all cDNA clones in your preferred vector: UTP18 (NM_016001)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UTP18
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UTP18
    Primer
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    OriGene qPCR primer pairs and template standards for UTP18
    OriGene qSTAR qPCR primer pairs in human, mouse for UTP18
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UTP18
      QuantiTect SYBR Green Assays in human, mouse, rat UTP18
      QuantiFast Probe-based Assays in human, mouse, rat UTP18

    Selected AceView cDNA sequences (see all 42):

    BE348718 CR618262 AI761175 BQ644221 CB148440 BC025276 BF594314 AW665649 
    AA286919 BM807302 AA281111 BM728330 BQ646118 BM989345 BI521248 AA576635 
    BP371469 BQ721576 BG187204 BM703231 BM464618 BF591164 AI656528 BM987331 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UTP18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCAGCTTT
    UTP18 Expression
    About this image


    UTP18 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
     
     Testis (Reproductive System)
    UTP18 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UTP18 Protein Expression
        Custom PCR Arrays for UTP18
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat UTP18
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP18

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for UTP18 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Utp181 , 5 UTP18, small subunit (SSU) processome component, homolog more1, 5 85.1(n)1
    81.75(a)1
      11 (58.84 cM)5
    2171091  NM_001013375.11  NP_001013393.11 
     938592435 
    chicken
    (Gallus gallus)
    Aves UTP181 UTP18 small subunit (SSU) processome component homolog more 68.5(n)
    63.14(a)
      417388  XM_003642314.2  XP_003642362.2 
    lizard
    (Anolis carolinensis)
    Reptilia UTP186
    UTP18 small subunit (SSU) processome component hom...
    59(a)
    1 ↔ 1
    2(117778191-117843277)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ071097.12   -- 72.73(n)    BJ071097.1 
    zebrafish
    (Danio rerio)
    Actinopterygii utp181 UTP18 small subunit (SSU) processome component homolog more 56.22(n)
    53.52(a)
      767797  NM_001076764.1  NP_001070232.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta wcd1 wicked 43.93(n)
    33.33(a)
      36831  NM_137277.3  NP_611121.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0280.96
    Protein B0280.9 (B0280.9) mRNA, complete cds
    28(a)
    1 ↔ 1
    III(7120904-7122895) WBGene00015104
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UTP18(YJL069C)4 Possible U3 snoRNP protein involved in maturation of more   --   10(312706-310922) 853376  NP_012466.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G140501 AT5G14050 49.35(n)
    40.22(a)
      831254  NM_121408.3  NP_196909.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g06032001 Os07g0603200 48.18(n)
    37.91(a)
      4343836  NM_001066746.1  NP_001060211.1 


    ENSEMBL Gene Tree for UTP18 (if available)
    TreeFam Gene Tree for UTP18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UTP18 gene

    Find genes that share paralogs with UTP18           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for UTP18
    PGOHUM00000235049


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UTP18 (see all 786)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs563029471,2
    C,F--49339546(+) CAAGCG/TATTCT 1 -- int12Minor allele frequency- T:0.50NA 4
    rs1825314771,2
    --49339643(+) GGTTTC/TACCAT 1 -- int10--------
    rs1434578751,2
    C--49339658(+) GCCAGA/GCTGGT 1 -- int10--------
    rs1871926131,2
    --49339662(+) GGCTGG/TTCTCA 1 -- int10--------
    rs1394747861,2
    C--49339735(+) CCACCA/GCACCC 1 -- int10--------
    rs733349611,2
    C,F--49339776(+) TTATGG/ATATAA 1 -- int13Minor allele frequency- A:0.15WA 122
    rs794101661,2
    C,F--49339779(+) TGGTAT/GAAATT 1 -- int15Minor allele frequency- G:0.24WA CSA NA 243
    rs1428194171,2
    C--49339936(+) TTGGTC/GACAGA 1 -- int10--------
    rs802742221,2
    --49339943(+) CAGATA/GAATTA 1 -- int10--------
    rs1151363341,2
    F--49339965(+) TTCTCC/TGAACA 1 -- int11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for UTP18 (49337889 - 49375297 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for UTP18: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UTP18
    DNA2.0 Custom Variant and Variant Library Synthesis for UTP18

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612816    OMIM disorders: --


    Find genes that share disorders with UTP18           About GenesLikeMe


    Export disorders for UTP18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UTP18 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with UTP18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. The small-subunit processome is a ribosome assembly intermediate. (PubMed id 15590835)1, 3 Bernstein K.A....Baserga S.J. (Eukaryotic Cell 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    6. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51096 HGNC: 24274 AceView: CGI-48 Ensembl:ENSG00000011260 euGenes: HUgn51096
    ECgene: UTP18 Kegg: 51096 H-InvDB: UTP18

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UTP18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UTP18 gene:
    Search GeneIP for patents involving UTP18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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