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Aliases for UTP14A Gene

Aliases for UTP14A Gene

  • UTP14, U3 Small Nucleolar Ribonucleoprotein, Homolog A (Yeast) 2 3
  • Serologically Defined Colon Cancer Antigen 16 2 3 4
  • Antigen NY-CO-16 3 4
  • SDCCAG16 3 4
  • U3 Small Nucleolar RNA-Associated Protein 14 Homolog A 3
  • DJ537K23.3 3
  • NYCO16 3

External Ids for UTP14A Gene

Previous HGNC Symbols for UTP14A Gene

  • SDCCAG16

Previous GeneCards Identifiers for UTP14A Gene

  • GC0XP127746
  • GC0XP128765
  • GC0XP128867
  • GC0XP129040
  • GC0XP118440

Summaries for UTP14A Gene

Entrez Gene Summary for UTP14A Gene

  • This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

GeneCards Summary for UTP14A Gene

UTP14A (UTP14, U3 Small Nucleolar Ribonucleoprotein, Homolog A (Yeast)) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes. An important paralog of this gene is UTP14C.

UniProtKB/Swiss-Prot for UTP14A Gene

  • May be required for ribosome biogenesis.

Gene Wiki entry for UTP14A Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP14A Gene

Genomics for UTP14A Gene

Regulatory Elements for UTP14A Gene

Genomic Location for UTP14A Gene

129,906,121 bp from pter
129,929,762 bp from pter
23,642 bases
Plus strand

Genomic View for UTP14A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UTP14A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP14A Gene

Proteins for UTP14A Gene

  • Protein details for UTP14A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    U3 small nucleolar RNA-associated protein 14 homolog A
    Protein Accession:
    Secondary Accessions:
    • A8K7A3
    • A8MVQ1
    • B4DQ08
    • E9PEL7
    • Q5JYF1

    Protein attributes for UTP14A Gene

    771 amino acids
    Molecular mass:
    87978 Da
    Quaternary structure:
    No Data Available
    • The human genome also contains the UTP14C gene, an autosomal retrotransposed copy of this X-linked gene. Evolution of autosomal retrogenes from X-linked progenitors compensates for X-chromosome silencing during male meiosis
    • Sequence=CAI42909.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for UTP14A Gene


neXtProt entry for UTP14A Gene

Proteomics data for UTP14A Gene at MOPED

Post-translational modifications for UTP14A Gene

Other Protein References for UTP14A Gene

No data available for DME Specific Peptides for UTP14A Gene

Domains for UTP14A Gene

Protein Domains for UTP14A Gene


Suggested Antigen Peptide Sequences for UTP14A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BVJ6
  • Belongs to the UTP14 family.
genes like me logo Genes that share domains with UTP14A: view

No data available for Gene Families for UTP14A Gene

Function for UTP14A Gene

Molecular function for UTP14A Gene

UniProtKB/Swiss-Prot Function: May be required for ribosome biogenesis.

Gene Ontology (GO) - Molecular Function for UTP14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 15383276
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with UTP14A: view
genes like me logo Genes that share phenotypes with UTP14A: view

miRNA for UTP14A Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for UTP14A Gene

Localization for UTP14A Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP14A Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for UTP14A Gene COMPARTMENTS Subcellular localization image for UTP14A gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for UTP14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IBA --
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with UTP14A: view

Pathways for UTP14A Gene

genes like me logo Genes that share pathways with UTP14A: view

Pathways by source for UTP14A Gene

1 KEGG pathway for UTP14A Gene

Gene Ontology (GO) - Biological Process for UTP14A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing --
GO:0030490 maturation of SSU-rRNA IBA --
genes like me logo Genes that share ontologies with UTP14A: view

Transcripts for UTP14A Gene

Unigene Clusters for UTP14A Gene

UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UTP14A Gene

No ASD Table

Relevant External Links for UTP14A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for UTP14A Gene

mRNA expression in normal human tissues for UTP14A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UTP14A Gene

SOURCE GeneReport for Unigene cluster for UTP14A Gene Hs.458598

mRNA Expression by UniProt/SwissProt for UTP14A Gene

Tissue specificity: Ubiquitously expressed.
genes like me logo Genes that share expressions with UTP14A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for UTP14A Gene

Orthologs for UTP14A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UTP14A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia UTP14A 35
  • 96.75 (n)
  • 95.97 (a)
UTP14A 36
  • 99 (a)
(Bos Taurus)
Mammalia UTP14A 35
  • 85.31 (n)
  • 79.92 (a)
UTP14A 36
  • 79 (a)
UTP14A 36
  • 79 (a)
(Canis familiaris)
Mammalia UTP14A 35
  • 86.68 (n)
  • 83.57 (a)
UTP14A 36
  • 83 (a)
(Mus musculus)
Mammalia Utp14a 35
  • 82.11 (n)
  • 77.75 (a)
Utp14a 16
Utp14a 36
  • 77 (a)
Utp14b 36
  • 67 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 59 (a)
(Rattus norvegicus)
Mammalia Utp14a 35
  • 81.74 (n)
  • 77.59 (a)
(Gallus gallus)
Aves -- 36
  • 51 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 48 (a)
(Danio rerio)
Actinopterygii Dr.16121 35
UTP14A 36
  • 45 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12301 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea F27C1.6 35
  • 47.57 (n)
  • 38.02 (a)
F27C1.6 36
  • 26 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP14 36
  • 23 (a)
Species with no ortholog for UTP14A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for UTP14A Gene

Gene Tree for UTP14A (if available)
Gene Tree for UTP14A (if available)

Paralogs for UTP14A Gene

Paralogs for UTP14A Gene

Selected SIMAP similar genes for UTP14A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with UTP14A: view

Variants for UTP14A Gene

Sequence variations from dbSNP and Humsavar for UTP14A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1055024 -- 129,929,482(+) ATTAA(C/G)CCCAT reference, missense
rs1055025 -- 129,929,497(+) GCAGA(A/G)GACGT reference, synonymous-codon
rs1055026 -- 129,929,500(+) GAAGA(C/T)GTGGG reference, synonymous-codon
rs1055027 -- 129,929,511(+) CTACC(A/G)GTCTT missense, reference
rs1055028 -- 129,929,527(+) AGGTC(A/G)GACCT synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for UTP14A Gene

Variant ID Type Subtype PubMed ID
nsv528290 CNV Gain 19592680

Relevant External Links for UTP14A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UTP14A Gene

Disorders for UTP14A Gene

No disorders were found for UTP14A Gene.

No data available for UniProtKB/Swiss-Prot for UTP14A Gene

Publications for UTP14A Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b. (PMID: 15289605) Rohozinski J. … Bishop C.E. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4

Products for UTP14A Gene

Sources for UTP14A Gene

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