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Aliases for UTP11L Gene

Aliases for UTP11L Gene

  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein (Yeast) 2 3
  • U3 SnoRNA-Associated Protein 11 3 4
  • UTP11-Like Protein 3 4
  • CGI94 3 6
  • Probable U3 Small Nucleolar RNA-Associated Protein 11 3
  • CGI-94 3

External Ids for UTP11L Gene

Summaries for UTP11L Gene

GeneCards Summary for UTP11L Gene

UTP11L (UTP11-Like, U3 Small Nucleolar Ribonucleoprotein (Yeast)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for UTP11L Gene

  • Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Wiki entry for UTP11L Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP11L Gene

Genomics for UTP11L Gene

Genomic Location for UTP11L Gene

Start:
38,009,258 bp from pter
End:
38,024,825 bp from pter
Size:
15,568 bases
Orientation:
Plus strand

Genomic View for UTP11L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UTP11L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP11L Gene

Regulatory Elements for UTP11L Gene

Proteins for UTP11L Gene

  • Protein details for UTP11L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y3A2-UTP11_HUMAN
    Recommended name:
    Probable U3 small nucleolar RNA-associated protein 11
    Protein Accession:
    Q9Y3A2
    Secondary Accessions:
    • A8K785
    • B4DJC6
    • D3DPT7
    • Q5VT93
    • Q9BS98
    • Q9NS31

    Protein attributes for UTP11L Gene

    Size:
    253 amino acids
    Molecular mass:
    30447 Da
    Quaternary structure:
    • Component of the ribosomal small subunit (SSU) processome.
    SequenceCaution:
    • Sequence=AAF75562.1; Type=Frameshift; Positions=14; Evidence={ECO:0000305};

    Alternative splice isoforms for UTP11L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UTP11L Gene

Proteomics data for UTP11L Gene at MOPED

Post-translational modifications for UTP11L Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys120 and Lys246

Other Protein References for UTP11L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UTP11L Gene

Domains for UTP11L Gene

Protein Domains for UTP11L Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

UTP11_HUMAN
Family:
  • Belongs to the UTP11 family.:
    • Q9Y3A2
genes like me logo Genes that share domains with UTP11L: view

No data available for Gene Families for UTP11L Gene

Function for UTP11L Gene

Molecular function for UTP11L Gene

UniProtKB/Swiss-Prot Function: Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Ontology (GO) - Molecular Function for UTP11L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 12559088
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with UTP11L: view

Phenotypes for UTP11L Gene

GenomeRNAi human phenotypes for UTP11L:
genes like me logo Genes that share phenotypes with UTP11L: view

miRNA for UTP11L Gene

miRTarBase miRNAs that target UTP11L

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for UTP11L Gene

Localization for UTP11L Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP11L Gene

Nucleus, nucleolus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UTP11L Gene COMPARTMENTS Subcellular localization image for UTP11L gene
Compartment Confidence
extracellular 4
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for UTP11L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 11860508
GO:0005730 nucleolus IDA 11860508
GO:0005737 cytoplasm IDA 11860508
GO:0032040 small-subunit processome IBA --
genes like me logo Genes that share ontologies with UTP11L: view

Pathways for UTP11L Gene

SuperPathways for UTP11L Gene

No Data Available

Gene Ontology (GO) - Biological Process for UTP11L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing IBA --
GO:0007399 nervous system development IMP 12559088
GO:0042274 ribosomal small subunit biogenesis IBA --
GO:0043065 positive regulation of apoptotic process IMP 12559088
genes like me logo Genes that share ontologies with UTP11L: view

No data available for Pathways by source for UTP11L Gene

Transcripts for UTP11L Gene

Unigene Clusters for UTP11L Gene

UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UTP11L Gene

No ASD Table

Relevant External Links for UTP11L Gene

GeneLoc Exon Structure for
UTP11L
ECgene alternative splicing isoforms for
UTP11L

Expression for UTP11L Gene

mRNA expression in normal human tissues for UTP11L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for UTP11L Gene

This gene is overexpressed in Muscle - Skeletal (7.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UTP11L Gene

SOURCE GeneReport for Unigene cluster for UTP11L Gene Hs.472038

genes like me logo Genes that share expressions with UTP11L: view

Orthologs for UTP11L Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP11L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UTP11L 36
  • 99.6 (n)
  • 99.6 (a)
UTP11L 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UTP11L 36
  • 91.44 (n)
  • 94.47 (a)
UTP11L 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UTP11L 36
  • 91.7 (n)
  • 94.47 (a)
UTP11L 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Utp11l 36
  • 86.3 (n)
  • 90.51 (a)
Utp11l 16
Utp11l 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UTP11L 37
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UTP11L 37
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Utp11l 36
  • 86.17 (n)
  • 90.12 (a)
chicken
(Gallus gallus)
Aves UTP11L 36
  • 73.39 (n)
  • 74.7 (a)
UTP11L 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UTP11L 37
  • 67 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.24106 36
tropical clawed frog
(Silurana tropicalis)
Amphibia utp11l 36
  • 69.3 (n)
  • 74.31 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2686 36
zebrafish
(Danio rerio)
Actinopterygii -- 36
utp11l 36
  • 64.12 (n)
  • 65.46 (a)
utp11l 37
  • 65 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004336 36
  • 52.48 (n)
  • 46.99 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1789 36
  • 47.86 (n)
  • 44.87 (a)
CG1789 37
  • 42 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C16C10.2 37
  • 37 (a)
OneToOne
CELE_C16C10.2 36
  • 49.86 (n)
  • 40.5 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL032C 36
  • 42.35 (n)
  • 33.05 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP11 36
  • 45.36 (n)
  • 34.78 (a)
UTP11 37
  • 32 (a)
OneToOne
UTP11 39
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F13508g 36
  • 45.26 (n)
  • 35.34 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons EDA14 36
  • 49.14 (n)
  • 38.5 (a)
rice
(Oryza sativa)
Liliopsida Os01g0810000 36
  • 48.92 (n)
  • 40.28 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC18G6.06 36
  • 48.29 (n)
  • 38.27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 43 (a)
OneToOne
Species with no ortholog for UTP11L:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP11L Gene

ENSEMBL:
Gene Tree for UTP11L (if available)
TreeFam:
Gene Tree for UTP11L (if available)

Paralogs for UTP11L Gene

No data available for Paralogs for UTP11L Gene

Variants for UTP11L Gene

Sequence variations from dbSNP and Humsavar for UTP11L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4440824 -- 38,015,034(+) gtttg(C/T)ttttt intron-variant
rs4525008 -- 38,015,316(+) GCACC(C/T)GGCCT intron-variant
rs5018050 -- 38,015,258(+) CTCAG(A/G)TGCCC intron-variant
rs6600446 -- 38,011,643(+) CACTG(C/T)TGTAG upstream-variant-2KB
rs6667423 -- 38,014,870(+) aactc(C/T)tgggc intron-variant

Relevant External Links for UTP11L Gene

HapMap Linkage Disequilibrium report
UTP11L

No data available for Structural Variations from Database of Genomic Variants (DGV) for UTP11L Gene

Disorders for UTP11L Gene

No disorders were found for UTP11L Gene.

No data available for UniProtKB/Swiss-Prot for UTP11L Gene

Publications for UTP11L Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4
  2. Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. (PMID: 11860508) Heese K. … Sawada T. (Eur. J. Neurosci. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4

Products for UTP11L Gene

Sources for UTP11L Gene

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