UTP11L Gene
protein-coding GIFtS : 48
GCID: GC01 P038475
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
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Aliasesfor UTP11L gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases UTP11-Like, U3 Small Nucleolar Ribonucleoprotein, (Yeast) 1 2 U3 SnoRNA-Associated Protein 112 3 UTP11-Like Protein2 3 CGI942 5 CGI-941 Probable U3 Small Nucleolar RNA-Associated Protein 112
Export aliases for UTP11L gene to outside databases Previous GC identifers: GC01P038148 GC01P038252 GC01P036596
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Summariesfor UTP11L gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: UTP11_HUMAN, Q9Y3A2 Function : Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)Gene Wiki entry for UTP11L
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Genomic Viewsfor UTP11L gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_032977.9 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the UTP11L gene promoter: E2F-4 E2F-3a Bach1 STAT1 E2F-5 E2F-2 C/EBPalpha E47 E2F-1 E2F Other transcription factors Search SABiosciences Chromatin IP Primers for UTP11L Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat UTP11L
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1p34.3 Ensembl cytogenetic band: 1p34.3 HGNC cytogenetic band: 1p34.3 UTP11L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P038475: view genomic region
(about GC identifiers )
Start:
38,474,930 bp from pter
End:
38,490,497 bp from pter
Size:
15,568 bases
Orientation:
plus strand
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Proteinsfor UTP11L gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: UTP11_HUMAN, Q9Y3A2 (See
protein sequence )Recommended Name: Probable U3 small nucleolar RNA-associated protein 11 Size : 253 amino acids; 30447 Da
Subunit : Component of the ribosomal small subunit (SSU) processome (By similarity)
Subcellular location : Nucleus, nucleolus (By similarity)
Sequence caution : Sequence=AAF75562.1; Type=Frameshift; Positions=14;
Secondary accessions : A8K785 D3DPT7 Q5VT93 Q9BS98 Q9NS31Explore the universe of human proteins at neXtProt for UTP11L: NX_Q9Y3A2 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9Y3A2 UTP11L Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_057121.2 ENSEMBL proteins: ENSP00000362105 ENSP00000437378 Human Recombinant Protein Products for UTP11L: Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view) : About this table
UTP11L for ontologies About GeneDecksing UTP11L Antibody Products: Assay Products for UTP11L:
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Protein
Domains / Familiesfor UTP11L gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
UTP11L for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q9Y3A2 ProtoNet protein and cluster: Q9Y3A2
1 Blocks protein family : IPB007144 Utp11 UniProtKB/Swiss-Prot: UTP11_HUMAN, Q9Y3A2 Similarity : Belongs to the UTP11 family
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Functionfor UTP11L gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: UTP11_HUMAN, Q9Y3A2 Function : Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity)
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
UTP11L for ontologies About GeneDecksing Phenotypes: 2 GenomeRNAi human phenotypes for UTP11L :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11L (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11LOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UTP11L (NM_016037 ) Sino Biological Human cDNA Clone for UTP11L DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UTP11L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UTP11L
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP11L
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Pathways & Interactionsfor UTP11L gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UTP11L STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)5/77 Interacting proteins for UTP11L (Q9Y3A2 3 ENSP00000362105 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 77 )About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
UTP11L for ontologies About GeneDecksing
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Drugs & Compoundsfor UTP11L gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for UTP11L Search CenterWatch for drugs/clinical trials and news about UTP11L / UTP11
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Transcriptsfor UTP11L gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for UTP11L gene: NM_016037.3 Unigene Cluster for UTP11L:
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) Hs.472038 [show with all ESTs ] Unigene Representative Sequence: NM_016037 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000483182 ENST00000486563 ENST00000373014 (uc001ccn.4 uc009vvm.3 uc010oil.2 )ENST00000488453 (uc001cco.4 ) ENST00000537711 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11L (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11LOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UTP11L (NM_016037 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UTP11L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UTP11L
Additional cDNA sequence: AF067802.1 AF151852.1 AK291900.1 AK296018.1 AK308377.1 BC005182.1
7 DOTS entries : DT.452757 DT.407172
DT.100780704 DT.100780705 DT.95150110 DT.121448642 DT.100728758 24/192 AceView cDNA sequences (see all 192 ):
AI240969 BM474886 BQ000735 AA700575 AA279763 CB141002 BQ082679 CN479474 AA314256 W60516 AK023587 BE617144 T95352 AA327697 AA604235 CD654277 CA432743 CF541143 CF541114 CF541113 BM710918 CN479988 CD677620 AA865759 GeneLoc Exon Structure
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Expression for UTP11L gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section UTP11L expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GTTTTCCGGTAbout this image UTP11L expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Ovary Primary Follicle Primary Oocyte Female Gametocytes, Germ Cells Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See UTP11L Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for UTP11L SOURCE GeneReport for Unigene cluster: Hs.472038 SABiosciences Expression via Pathway-Focused PCR Array including UTP11L : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UTP11LBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat UTP11L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UTP11L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UTP11L In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP11L
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Orthologsfor UTP11L gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for UTP11L gene from 10/34 species (see all 34 ) About this table
ENSEMBL Gene Tree for UTP11L (if available)TreeFam Gene Tree for UTP11L (if available)
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Paralogsfor UTP11L gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor UTP11L gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for UTP11L (38474930 - 38490497 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for UTP11L: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UTP11L
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Disorders
/ Diseasesfor UTP11L gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
UTP11L for disorders About GeneDecksing
OMIM gene information: 609440
OMIM disorders : --2 diseases for UTP11L : About MalaCards alzheimer's disease malaria Export disorders for UTP11L gene to outside databases
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Publicationsfor UTP11L gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for UTP11L gene, integrated from 9 sources (see all 17 ): (articles sorted by number of sources associating them with UTP11L) Utopia : connect your pdf to the dynamic world of online information
Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093) 1 , 2 , 3 Lai C.H....Lin W. (2000) The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 1 , 2 Gregory S.G.... Bentley D.R. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. (PubMed id 11860508) 1 , 3 Heese K....Sawada T. (2002) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692) 2 Rigbolt K.T....Blagoev B. (2011) Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048) 1 Danielsen J.M....Nielsen M.L. (2011) Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764) 1 Tatham M.H....Hay R.T. (2011)
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External Searches for UTP11L gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing UTP11L gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing UTP11L gene
(According to HUGE )
About This Section --
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Specialized Databases showing UTP11L gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for UTP11L Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for UTP11L gene: Search GeneIP for patents involving UTP11L GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor UTP11L gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for UTP11L OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for UTP11L OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UTP11L OriGene Protein Over-expression Lysate for UTP11L Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for UTP11L OriGene 3'-UTR Clone for UTP11L OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11L OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UTP11L Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for UTP11L OriGene Custom Protein Services for UTP11L OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UTP11L QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UTP11L QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat UTP11L QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat UTP11L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UTP11L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UTP11L
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UTP11L
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UTP11L
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