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Aliases for UTP11 Gene

Aliases for UTP11 Gene

  • UTP11, Small Subunit Processome Component Homolog (S. Cerevisiae) 2 3 5
  • U3 SnoRNA-Associated Protein 11 3 4
  • UTP11-Like Protein 3 4
  • UTP11L 3 4
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein (Yeast) 2
  • Probable U3 Small Nucleolar RNA-Associated Protein 11 3
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein 3
  • CGI-94 3
  • CGI94 3

External Ids for UTP11 Gene

Previous HGNC Symbols for UTP11 Gene

  • UTP11L

Summaries for UTP11 Gene

GeneCards Summary for UTP11 Gene

UTP11 (UTP11, Small Subunit Processome Component Homolog (S. Cerevisiae)) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression.

UniProtKB/Swiss-Prot for UTP11 Gene

  • Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Wiki entry for UTP11 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP11 Gene

Genomics for UTP11 Gene

Regulatory Elements for UTP11 Gene

Enhancers for UTP11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F037907 0.4 ENCODE 11.1 -101.4 -101411 1.6 EGR2 INPP5B FHL3 UTP11 ENSG00000230955 MTF1 RNU6-584P LOC105378651
GH01F038053 1.2 FANTOM5 Ensembl ENCODE 10.7 +44.1 44061 0.6 HDGF TBP WRNIP1 EBF1 ZIC2 RELA ZFHX2 POLR2A ZNF366 ELK1 UTP11 FHL3 ENSG00000224592 ENSG00000223589
GH01F037900 1.1 Ensembl ENCODE 10.6 -107.7 -107699 2.0 SP1 PKNOX1 MTA2 RNF2 IKZF1 EED SPI1 RELA INPP5B FHL3 MTF1 ENSG00000230955 UTP11 RNU6-584P LOC105378651
GH01F037930 1 ENCODE 10.5 -77.5 -77543 3.2 HDGF ATF1 PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A YY1 GLIS2 ZNF143 SF3A3 GNL2 FHL3 UTP11 SNIP1 LOC105378651 RNU6-584P
GH01F037858 0.2 ENCODE 10.4 -149.4 -149404 3.4 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 SF3A3 GNL2 SNIP1 INPP5B UTP11 FTH1P1 FHL3 ENSG00000230955 MTF1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around UTP11 on UCSC Golden Path with GeneCards custom track

Genomic Location for UTP11 Gene

Chromosome:
1
Start:
38,009,258 bp from pter
End:
38,024,825 bp from pter
Size:
15,568 bases
Orientation:
Plus strand

Genomic View for UTP11 Gene

Genes around UTP11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UTP11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UTP11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP11 Gene

Proteins for UTP11 Gene

  • Protein details for UTP11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y3A2-UTP11_HUMAN
    Recommended name:
    Probable U3 small nucleolar RNA-associated protein 11
    Protein Accession:
    Q9Y3A2
    Secondary Accessions:
    • A8K785
    • B4DJC6
    • D3DPT7
    • Q5VT93
    • Q9BS98
    • Q9NS31

    Protein attributes for UTP11 Gene

    Size:
    253 amino acids
    Molecular mass:
    30447 Da
    Quaternary structure:
    • Component of the ribosomal small subunit (SSU) processome.
    SequenceCaution:
    • Sequence=AAF75562.1; Type=Frameshift; Positions=14; Evidence={ECO:0000305};

    Alternative splice isoforms for UTP11 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UTP11 Gene

Post-translational modifications for UTP11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UTP11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UTP11 Gene

Domains & Families for UTP11 Gene

Protein Domains for UTP11 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for UTP11 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y3A2

UniProtKB/Swiss-Prot:

UTP11_HUMAN :
  • Belongs to the UTP11 family.
Family:
  • Belongs to the UTP11 family.
genes like me logo Genes that share domains with UTP11: view

No data available for Gene Families for UTP11 Gene

Function for UTP11 Gene

Molecular function for UTP11 Gene

UniProtKB/Swiss-Prot Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Ontology (GO) - Molecular Function for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 12559088
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with UTP11: view
genes like me logo Genes that share phenotypes with UTP11: view

Animal Model Products

miRNA for UTP11 Gene

miRTarBase miRNAs that target UTP11

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UTP11 Gene

Localization for UTP11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP11 Gene

Nucleus, nucleolus.

Gene Ontology (GO) - Cellular Components for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 11860508
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005730 nucleolus IDA 11860508
GO:0005737 cytoplasm IDA 11860508
genes like me logo Genes that share ontologies with UTP11: view

No data available for Subcellular locations from COMPARTMENTS for UTP11 Gene

Pathways & Interactions for UTP11 Gene

genes like me logo Genes that share pathways with UTP11: view

Gene Ontology (GO) - Biological Process for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing TAS --
GO:0007399 nervous system development IMP 12559088
GO:0042274 ribosomal small subunit biogenesis IBA --
GO:0043065 positive regulation of apoptotic process IMP 12559088
genes like me logo Genes that share ontologies with UTP11: view

No data available for SIGNOR curated interactions for UTP11 Gene

Transcripts for UTP11 Gene

Unigene Clusters for UTP11 Gene

UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UTP11 Gene

No ASD Table

Relevant External Links for UTP11 Gene

GeneLoc Exon Structure for
UTP11
ECgene alternative splicing isoforms for
UTP11

Expression for UTP11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of UTP11 Gene:

UTP11

SOURCE GeneReport for Unigene cluster for UTP11 Gene:

Hs.472038
genes like me logo Genes that share expression patterns with UTP11: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for UTP11 Gene

Orthologs for UTP11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UTP11L 34 35
  • 99.6 (n)
dog
(Canis familiaris)
Mammalia UTP11L 34 35
  • 91.7 (n)
cow
(Bos Taurus)
Mammalia UTP11L 34 35
  • 91.44 (n)
mouse
(Mus musculus)
Mammalia Utp11l 34 16 35
  • 86.3 (n)
rat
(Rattus norvegicus)
Mammalia Utp11l 34
  • 86.17 (n)
oppossum
(Monodelphis domestica)
Mammalia UTP11L 35
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UTP11L 35
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves UTP11L 34 35
  • 73.39 (n)
lizard
(Anolis carolinensis)
Reptilia UTP11L 35
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia utp11l 34
  • 69.3 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.24106 34
zebrafish
(Danio rerio)
Actinopterygii utp11l 34 35
  • 64.12 (n)
-- 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2686 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004336 34
  • 52.48 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG1789 34 35
  • 47.86 (n)
worm
(Caenorhabditis elegans)
Secernentea CELE_C16C10.2 34
  • 49.86 (n)
C16C10.2 35
  • 37 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP11 34 35 37
  • 45.36 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F13508g 34
  • 45.26 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL032C 34
  • 42.35 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons EDA14 34
  • 49.14 (n)
rice
(Oryza sativa)
Liliopsida Os01g0810000 34
  • 48.92 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC18G6.06 34
  • 48.29 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 43 (a)
OneToOne
Species where no ortholog for UTP11 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP11 Gene

ENSEMBL:
Gene Tree for UTP11 (if available)
TreeFam:
Gene Tree for UTP11 (if available)

Paralogs for UTP11 Gene

No data available for Paralogs for UTP11 Gene

Variants for UTP11 Gene

Sequence variations from dbSNP and Humsavar for UTP11 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10749870 -- 38,024,563(+) GCGCC(C/T)GGCTA utr-variant-3-prime
rs111295940 -- 38,019,752(+) GTGTC(A/G)GGATT intron-variant
rs111498247 -- 38,012,887(+) CCCAC(A/G)AGTGC intron-variant
rs111723651 -- 38,022,439(+) TGGGC(C/T)CAAGT intron-variant
rs111766985 -- 38,017,427(+) GGGGA(A/C)AGTTA intron-variant

Variation tolerance for UTP11 Gene

Residual Variation Intolerance Score: 42.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.77; 16.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for UTP11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UTP11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for UTP11 Gene

Disorders for UTP11 Gene

Relevant External Links for UTP11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UTP11
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UTP11

No disorders were found for UTP11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UTP11 Gene

Publications for UTP11 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. (PMID: 11860508) Heese K. … Sawada T. (Eur. J. Neurosci. 2002) 2 3 64

Products for UTP11 Gene

Sources for UTP11 Gene

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