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Aliases for UTP11 Gene

Aliases for UTP11 Gene

  • UTP11, Small Subunit Processome Component Homolog (S. Cerevisiae) 2 3
  • UTP11L 3 4 5
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein (Yeast) 2 5
  • U3 SnoRNA-Associated Protein 11 3 4
  • UTP11-Like Protein 3 4
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein 3
  • CGI-94 3
  • CGI94 3

External Ids for UTP11 Gene

Previous HGNC Symbols for UTP11 Gene

  • UTP11L

Summaries for UTP11 Gene

GeneCards Summary for UTP11 Gene

UTP11 (UTP11, Small Subunit Processome Component Homolog (S. Cerevisiae)) is a Protein Coding gene. Among its related pathways are Gene Expression and rRNA processing.

UniProtKB/Swiss-Prot for UTP11 Gene

  • Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Wiki entry for UTP11 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP11 Gene

Genomics for UTP11 Gene

Regulatory Elements for UTP11 Gene

Enhancers for UTP11 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around UTP11 on UCSC Golden Path with GeneCards custom track

Genomic Location for UTP11 Gene

Chromosome:
1
Start:
38,009,258 bp from pter
End:
38,024,825 bp from pter
Size:
15,568 bases
Orientation:
Plus strand

Genomic View for UTP11 Gene

Genes around UTP11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UTP11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UTP11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP11 Gene

Proteins for UTP11 Gene

  • Protein details for UTP11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y3A2-UTP11_HUMAN
    Recommended name:
    Probable U3 small nucleolar RNA-associated protein 11
    Protein Accession:
    Q9Y3A2
    Secondary Accessions:
    • A8K785
    • B4DJC6
    • D3DPT7
    • Q5VT93
    • Q9BS98
    • Q9NS31

    Protein attributes for UTP11 Gene

    Size:
    253 amino acids
    Molecular mass:
    30447 Da
    Quaternary structure:
    • Component of the ribosomal small subunit (SSU) processome.
    SequenceCaution:
    • Sequence=AAF75562.1; Type=Frameshift; Positions=14; Evidence={ECO:0000305};

    Alternative splice isoforms for UTP11 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UTP11 Gene

Proteomics data for UTP11 Gene at MOPED

Post-translational modifications for UTP11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UTP11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UTP11 Gene

Domains & Families for UTP11 Gene

Protein Domains for UTP11 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for UTP11 Gene

Graphical View of Domain Structure for InterPro Entry

Q9Y3A2

UniProtKB/Swiss-Prot:

UTP11_HUMAN :
  • Belongs to the UTP11 family.
Family:
  • Belongs to the UTP11 family.
genes like me logo Genes that share domains with UTP11: view

No data available for Gene Families for UTP11 Gene

Function for UTP11 Gene

Molecular function for UTP11 Gene

UniProtKB/Swiss-Prot Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.
genes like me logo Genes that share phenotypes with UTP11: view

Animal Model Products

miRNA for UTP11 Gene

miRTarBase miRNAs that target UTP11

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UTP11 Gene

Localization for UTP11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP11 Gene

Nucleus, nucleolus.

Gene Ontology (GO) - Cellular Components for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 11860508
genes like me logo Genes that share ontologies with UTP11: view

No data available for Subcellular locations from COMPARTMENTS for UTP11 Gene

Pathways & Interactions for UTP11 Gene

genes like me logo Genes that share pathways with UTP11: view

Pathways by source for UTP11 Gene

Gene Ontology (GO) - Biological Process for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing IEA,TAS --
genes like me logo Genes that share ontologies with UTP11: view

No data available for SIGNOR curated interactions for UTP11 Gene

Drugs & Compounds for UTP11 Gene

No Compound Related Data Available

Transcripts for UTP11 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for UTP11 Gene

No ASD Table

Relevant External Links for UTP11 Gene

GeneLoc Exon Structure for
UTP11
ECgene alternative splicing isoforms for
UTP11

Expression for UTP11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with UTP11: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for UTP11 Gene

Orthologs for UTP11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP11 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia UTP11L 35
  • 91.44 (n)
  • 94.47 (a)
UTP11L 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UTP11L 35
  • 91.7 (n)
  • 94.47 (a)
UTP11L 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Utp11l 35
  • 86.3 (n)
  • 90.51 (a)
Utp11l 16
Utp11l 36
  • 91 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia UTP11L 35
  • 99.6 (n)
  • 99.6 (a)
UTP11L 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Utp11l 35
  • 86.17 (n)
  • 90.12 (a)
oppossum
(Monodelphis domestica)
Mammalia UTP11L 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UTP11L 36
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves UTP11L 35
  • 73.39 (n)
  • 74.7 (a)
UTP11L 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UTP11L 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia utp11l 35
  • 69.3 (n)
  • 74.31 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.24106 35
zebrafish
(Danio rerio)
Actinopterygii -- 35
utp11l 35
  • 64.12 (n)
  • 65.46 (a)
utp11l 36
  • 65 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2686 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004336 35
  • 52.48 (n)
  • 46.99 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG1789 35
  • 47.86 (n)
  • 44.87 (a)
CG1789 36
  • 42 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_C16C10.2 35
  • 49.86 (n)
  • 40.5 (a)
C16C10.2 36
  • 37 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL032C 35
  • 42.35 (n)
  • 33.05 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F13508g 35
  • 45.26 (n)
  • 35.34 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP11 35
  • 45.36 (n)
  • 34.78 (a)
UTP11 36
  • 32 (a)
OneToOne
UTP11 38
thale cress
(Arabidopsis thaliana)
eudicotyledons EDA14 35
  • 49.14 (n)
  • 38.5 (a)
rice
(Oryza sativa)
Liliopsida Os01g0810000 35
  • 48.92 (n)
  • 40.28 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC18G6.06 35
  • 48.29 (n)
  • 38.27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
OneToOne
Species with no ortholog for UTP11:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP11 Gene

ENSEMBL:
Gene Tree for UTP11 (if available)
TreeFam:
Gene Tree for UTP11 (if available)

Paralogs for UTP11 Gene

No data available for Paralogs for UTP11 Gene

Variants for UTP11 Gene

Sequence variations from dbSNP and Humsavar for UTP11 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs4440824 -- 38,015,034(+) gtttg(C/T)ttttt intron-variant
rs5018050 -- 38,015,258(+) CTCAG(A/G)TGCCC intron-variant
rs4525008 -- 38,015,316(+) GCACC(C/T)GGCCT intron-variant
rs6600446 -- 38,011,643(+) CACTG(C/T)TGTAG upstream-variant-2KB
rs6687778 -- 38,016,945(+) TTGTT(A/G)GCGAT intron-variant

Variation tolerance for UTP11 Gene

Residual Variation Intolerance Score: 42.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.77; 16.15% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for UTP11 Gene

Disorders for UTP11 Gene

Relevant External Links for UTP11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UTP11
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UTP11

No disorders were found for UTP11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UTP11 Gene

Publications for UTP11 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4 67
  2. Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. (PMID: 11860508) Heese K. … Sawada T. (Eur. J. Neurosci. 2002) 2 3
  3. Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. (PMID: 25693804) Diner B.A. … Cristea I.M. (Mol. Cell Proteomics 2015) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3

Products for UTP11 Gene

Sources for UTP11 Gene

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