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Aliases for UTP11 Gene

Aliases for UTP11 Gene

  • UTP11, Small Subunit Processome Component 2 3 5
  • U3 SnoRNA-Associated Protein 11 3 4
  • UTP11-Like Protein 3 4
  • UTP11L 3 4
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein (Yeast) 2
  • Probable U3 Small Nucleolar RNA-Associated Protein 11 3
  • UTP11, Small Subunit Processome Component Homolog 3
  • UTP11-Like, U3 Small Nucleolar Ribonucleoprotein 3
  • CGI-94 3
  • CGI94 3

External Ids for UTP11 Gene

Previous HGNC Symbols for UTP11 Gene

  • UTP11L

Summaries for UTP11 Gene

GeneCards Summary for UTP11 Gene

UTP11 (UTP11, Small Subunit Processome Component) is a Protein Coding gene. Among its related pathways are Gene Expression and rRNA processing in the nucleus and cytosol.

UniProtKB/Swiss-Prot for UTP11 Gene

  • Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Wiki entry for UTP11 Gene

Additional gene information for UTP11 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UTP11 Gene

Genomics for UTP11 Gene

GeneHancer (GH) Regulatory Elements for UTP11 Gene

Promoters and enhancers for UTP11 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I038008 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 550.8 +3.7 3652 9.3 CLOCK MLX ZFP64 DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC UTP11 SF3A3 INPP5B SNIP1 C1orf109 RNU6-510P FTH1P1 RSPO1 MTF1 ENSG00000230955
GH01I037858 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.4 -149.4 -149403 3.4 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B MTF1 ENSG00000230955 SF3A3 SNIP1 GNL2 INPP5B UTP11 C1orf109 FHL3
GH01I038989 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 10.4 +982.0 982013 4 HDGF SMAD1 FOXA2 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 AKIRIN1 NDUFS5 RHBDL2 GJA9 MYCBP UTP11 PIR42637 GC01M038902
GH01I037930 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.5 -77.5 -77543 3.2 HDGF PKNOX1 ATF1 ZFP64 ARID4B SIN3A YY1 TCF12 GLIS2 E2F8 LOC105378651 INPP5B SF3A3 SNIP1 C1orf109 GNL2 FHL3 UTP11 RNU6-584P
GH01I037810 Enhancer 1 Ensembl ENCODE 9.8 -198.2 -198157 0.6 HDGF RB1 ARID4B RAD21 ZNF335 ZNF143 CREM SMARCA5 PHF21A CEBPB GC01M037825 GC01M037828 PIR40914 PIR49672 PIR56555 PIR60496 INPP5B ENSG00000230955 MTF1 EPHA10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around UTP11 on UCSC Golden Path with GeneCards custom track

Genomic Locations for UTP11 Gene

Genomic Locations for UTP11 Gene
15,568 bases
Plus strand

Genomic View for UTP11 Gene

Genes around UTP11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UTP11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UTP11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UTP11 Gene

Proteins for UTP11 Gene

  • Protein details for UTP11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable U3 small nucleolar RNA-associated protein 11
    Protein Accession:
    Secondary Accessions:
    • A8K785
    • B4DJC6
    • D3DPT7
    • Q5VT93
    • Q9BS98
    • Q9NS31

    Protein attributes for UTP11 Gene

    253 amino acids
    Molecular mass:
    30447 Da
    Quaternary structure:
    • Component of the ribosomal small subunit (SSU) processome.
    • Sequence=AAF75562.1; Type=Frameshift; Positions=14; Evidence={ECO:0000305};

    Alternative splice isoforms for UTP11 Gene


neXtProt entry for UTP11 Gene

Post-translational modifications for UTP11 Gene

No Post-translational modifications

Other Protein References for UTP11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UTP11 Gene

Domains & Families for UTP11 Gene

Gene Families for UTP11 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for UTP11 Gene


Suggested Antigen Peptide Sequences for UTP11 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the UTP11 family.
  • Belongs to the UTP11 family.
genes like me logo Genes that share domains with UTP11: view

Function for UTP11 Gene

Molecular function for UTP11 Gene

UniProtKB/Swiss-Prot Function:
Involved in nucleolar processing of pre-18S ribosomal RNA.

Gene Ontology (GO) - Molecular Function for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding HDA 22658674
GO:0005515 protein binding IPI 12559088
genes like me logo Genes that share ontologies with UTP11: view
genes like me logo Genes that share phenotypes with UTP11: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UTP11 Gene

Localization for UTP11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UTP11 Gene

Nucleus, nucleolus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UTP11 gene
Compartment Confidence
nucleus 5
extracellular 4
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 11860508
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005730 nucleolus IDA 11860508
GO:0005737 cytoplasm IDA 11860508
genes like me logo Genes that share ontologies with UTP11: view

Pathways & Interactions for UTP11 Gene

genes like me logo Genes that share pathways with UTP11: view

Gene Ontology (GO) - Biological Process for UTP11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006364 rRNA processing IBA,TAS --
GO:0007399 nervous system development IMP 12559088
GO:0042274 ribosomal small subunit biogenesis IBA --
GO:0043065 positive regulation of apoptotic process IMP 12559088
genes like me logo Genes that share ontologies with UTP11: view

No data available for SIGNOR curated interactions for UTP11 Gene

Drugs & Compounds for UTP11 Gene

No Compound Related Data Available

Transcripts for UTP11 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for UTP11 Gene

No ASD Table

Relevant External Links for UTP11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for UTP11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of UTP11 Gene:


Evidence on tissue expression from TISSUES for UTP11 Gene

  • Muscle(4.4)
  • Nervous system(4.4)
genes like me logo Genes that share expression patterns with UTP11: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for UTP11 Gene

Orthologs for UTP11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UTP11 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia UTP11L 33 34
  • 99.6 (n)
(Canis familiaris)
Mammalia UTP11L 33 34
  • 91.7 (n)
(Bos Taurus)
Mammalia UTP11L 33 34
  • 91.44 (n)
(Mus musculus)
Mammalia Utp11l 33 34
  • 86.3 (n)
Utp11 16
(Rattus norvegicus)
Mammalia Utp11l 33
  • 86.17 (n)
(Monodelphis domestica)
Mammalia UTP11L 34
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia UTP11L 34
  • 77 (a)
(Gallus gallus)
Aves UTP11L 33 34
  • 73.39 (n)
(Anolis carolinensis)
Reptilia UTP11L 34
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia utp11l 33
  • 69.3 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.24106 33
(Danio rerio)
Actinopterygii utp11l 33 34
  • 64.12 (n)
-- 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2686 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004336 33
  • 52.48 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG1789 33 34
  • 47.86 (n)
(Caenorhabditis elegans)
Secernentea CELE_C16C10.2 33
  • 49.86 (n)
C16C10.2 34
  • 37 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UTP11 33 34 36
  • 45.36 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F13508g 33
  • 45.26 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_ABL032C 33
  • 42.35 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons EDA14 33
  • 49.14 (n)
(Oryza sativa)
Liliopsida Os01g0810000 33
  • 48.92 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPAC18G6.06 33
  • 48.29 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 43 (a)
Species where no ortholog for UTP11 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UTP11 Gene

Gene Tree for UTP11 (if available)
Gene Tree for UTP11 (if available)

Paralogs for UTP11 Gene

No data available for Paralogs for UTP11 Gene

Variants for UTP11 Gene

Sequence variations from dbSNP and Humsavar for UTP11 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000068982 -- 38,013,233(+) G/C intron_variant
rs1000085597 -- 38,019,681(+) G/A intron_variant
rs1001312702 -- 38,024,418(+) C/T 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1001364393 -- 38,018,857(+) T/C intron_variant
rs1001589185 -- 38,012,701(+) C/A/G upstream_transcript_variant

Variation tolerance for UTP11 Gene

Residual Variation Intolerance Score: 42.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.77; 16.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UTP11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for UTP11 Gene

Disorders for UTP11 Gene

No disorders were found for UTP11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UTP11 Gene

Publications for UTP11 Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai CH … Lin W (Genome research 2000) 2 3 4 58
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  5. Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain. (PMID: 11860508) Heese K … Sawada T (The European journal of neuroscience 2002) 2 3 58

Products for UTP11 Gene

Sources for UTP11 Gene

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