Aliases for UST Gene
External Ids for UST Gene
Previous GeneCards Identifiers for UST Gene
Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]
GeneCards Summary for UST Gene
UST (Uronyl 2-Sulfotransferase) is a Protein Coding gene. Diseases associated with UST include Liver Inflammatory Pseudotumor and Female Stress Incontinence. Among its related pathways are Defective B4GALT7 causes EDS, progeroid type and dermatan sulfate biosynthesis. GO annotations related to this gene include sulfotransferase activity and galactosylceramide sulfotransferase activity. An important paralog of this gene is HS2ST1.
UniProtKB/Swiss-Prot for UST Gene
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.