Aliases for UST Gene
External Ids for UST Gene
Previous GeneCards Identifiers for UST Gene
Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]
GeneCards Summary for UST Gene
UST (Uronyl 2-Sulfotransferase) is a Protein Coding gene. Diseases associated with UST include Liver Inflammatory Pseudotumor and Female Stress Incontinence. Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and Glycosaminoglycan metabolism. GO annotations related to this gene include sulfotransferase activity and galactosylceramide sulfotransferase activity. An important paralog of this gene is HS2ST1.
UniProtKB/Swiss-Prot for UST Gene
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.