V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

USP6 Gene

protein-coding GIFtS: 59

GC17P004972

ubiquitin specific peptidase 6 (Tre-2 oncogene)
(Previous name: ubiquitin specific protease 6 (Tre-2 oncogene) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: HRP1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 3.1.2.15 ^³
HRP1 ^², ³
OTTHUMP00000125301 ^²
TRE17 ^¹, ²
TRE2 ^², ³, ⁵
Tre-2 ^¹, ²
Tre2 ^¹
USP6-short ^²

Descriptions
Deubiquitinating enzyme 6 ^³
Proto-oncogene TRE-2 ^³
Ubiquitin thioesterase 6 ^³
Ubiquitin-specific-processing protease 6 ^³
hyperpolymorphic gene 1 ^²
tre-2 oncogene ^²
ubiquitin specific peptidase 6 (Tre-2 oncogene) ^²
ubiquitin specific peptidase 6- ^²
ubiquitin specific protease 6 ^²
ubiquitin specific protease 6 (Tre-2 oncogene) ^¹, ²
ubiquitin-specific protease USP6 ^²

External Ids
HGNC: 12629¹
Entrez Gene: 9098²
UniProtKB: P35125³
Ensembl: ENSG00000129204⁷

Search outside databases for aliases for USP6 gene

Previous GC identifers: GC17P005451 GC17P005369 GC17P004976 GC17P005232

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125

Function: Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin

moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity

Gene Wiki entry for USP6

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the USP6 gene

Entrez Gene cytogenetic band: 17p13 Ensembl cytogenetic band: 17p13.2 HGNC cytogenetic band: 17p13

USP6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P004972: (about GC identifiers)

Start:	4,960,457 bp from pter
End:	5,019,053 bp from pter
Size:	58,597 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000017.9 NT_010718.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125 (See protein sequence)

Recommended Name: Ubiquitin carboxyl-terminal hydrolase 6

Size: 1406 amino acids; 158658 Da

Miscellaneous: The USP6 gene only exists in the primate lineage

Secondary accessions: Q15634 Q86WP6 Q8IWT4

Alternative splicing: 3 isoforms: P35125-1 P35125-2 P35125-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004496.2

ENSEMBL proteins:

ENSP00000380022 ENSP00000350074 ENSP00000328010 ENSP00000305473 ENSP00000250066 ENSP00000250067

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (USP6)
	Human Recombinant Proteins from Abnova (USP6)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005764	lysosome	TAS	9827704

About this table

Antibodies for USP6:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for USP6
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (USP6), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (USP6)
	Novus Biologicals Antibodies for USP6

Assays for USP6:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P35125

ProtoNet protein and cluster: P35125

2 Blocks protein families:

IPB000195 RabGAP/TBC domain

IPB001394 Ubiquitin thiolesterase

UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125

Similarity: Belongs to the peptidase C19 family

Similarity: Contains 1 Rab-GAP TBC domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (USP6)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (USP6)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001039674

Applied Biosystems Silencer® siRNAs for USP6

Sigma-Aldrich siRNA and siRNA Panels for USP6

Sigma-Aldrich shRNA Panels and shRNA for USP6

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004505
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004505
untagged cDNA clones in CMV expression vector (see all 5): NM_001039674

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004505

UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125

Function: Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin

moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity

Catalytic activity: Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol

Enzyme Number (IUBMB): EC 3.1.2.15

Genatlas biochemistry entry for USP6:

ubiquitin specific protease 6,hyperpolymorphic gene 1,deubiquitin enzyme family

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003676	nucleic acid binding	TAS	1565468
GO:0004197	cysteine-type endopeptidase activity	TAS	9827704
GO:0004221	ubiquitin thiolesterase activity	IEA	--
GO:0005097	Rab GTPase activator activity	IEA	--
GO:0005515	protein binding	IPI	16555005

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for USP6 (Your Favorite Gene powered by Ingenuity)

Protein Ubiquitination Pathway

GeneDecks USP6 for the pathways selected above

About GeneDecksing

5/42 Interacting proteins for USP6 (ENSP00000305473³ P35125^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 42 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ANKRD44	Q8N8A2¹	EBI-954590, EBI-1245329
MYL2	P10916¹	EBI-954590, EBI-725770
FOS	ENSP00000306245³	STRING (score=.972)
SRC	ENSP00000362659³	STRING (score=.962)
AKT1	ENSP00000270202³	STRING (score=.948)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006464	protein modification process	NAS	9827704
GO:0006511	ubiquitin-dependent protein catabolic process	IEA	--
GO:0032313	regulation of Rab GTPase activity	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for USP6

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for USP6

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (USP6)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (USP6)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001039674

Sigma-Aldrich siRNA and siRNA Panels for USP6

Sigma-Aldrich shRNA Panels and shRNA for USP6

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004505

REFSEQ mRNAs for USP6 gene:

NM_004505.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004505

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004505
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004505
                                 untagged cDNA clones in CMV expression vector (see all 5): NM_001039674

Additional cDNA sequence:

AB449915.1 AY143550.1 BX647719.1 X78261.1

9 DOTS entries:

DT.100037996 DT.100824934 DT.101984339 DT.120915753 DT.304019 DT.102834044 DT.95289961 DT.120953569

DT.97776537

24/50 AceView cDNA sequences (see all 50 ):

AL042528 AL042432 BE044069 AL044255 AY143550 BC029495 AL041793 BV200185

AA328699 BV200183 BV200181 BV204922 BV202000 BV200177 X63547 BV185478

BV204923 AA813383 NM_004505 AL696358 BV200187 AA922552 BV200178 BX647719

highest scoring ESTs for USP6:

AA328699 AA813383 AA846445 AI147443 AI150125 AI208018 AI419876 AL041793 AL042432 AL042528

Unigene Cluster for USP6:

Ubiquitin specific peptidase 6 (Tre-2 oncogene)

Hs.448851 [show with all ESTs]

Unigene Representative Sequence: BX647719

GeneLoc Exon Structure

6 Ensembl transcripts including schematic representations:

ENST00000396805 ENST00000357482 ENST00000332776 ENST00000304328 ENST00000250066 ENST00000250067

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

USP6 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for USP6

¹ / ² / ³

9 probe-sets matching USP6 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1613_s_at²^{, 3}	U95-A	3	1.00	0.49	0.16	0.39	X63546	0.60	0.75	0.68	1
1614_s_at²^{, 3}	U95-A	8	1.00	0.22	0.90	0.64	X63546	0.60	0.75	0.68	1
31526_f_at²^{, 3}	U95-A	5	1.00	0.21	0.93	1.25	X63547	0.60	0.73	0.67	1
34677_f_at²^{, 3}	U95-A	5	1.00	0.20	0.96	1.32	AJ012755	0.20	0.04	0.14	3
45403_f_at²^{, 3}	U95-B	5	0.88	0.19	0.97	1.41	AI962621	0.20	0.05	0.15	3
206405_x_at²^{, 3}	U133-A	5	1.00	0.66	--	--	NM_004505	0.60	1.00	0.82	1
206405_x_at²	U133Plus2	5	1.00	0.66	--	--	--	--	--	--	--
1555063_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--
1555065_x_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.448851
Expression variation in blood from EXPOLDB for USP6
UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125
Tissue specificity: Testis specific. Expressed in various cancer cell lines

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for USP6 gene from 2 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
worm (Caenorhabditis elegans)	H34C03.2³	IV(6757531-6761964)	ubiquitin carboxy-terminal hydrolase	51(a)	--
tropical clawed frog (Silurana tropicalis)	Str.11864²	--	Transcribed sequences	85.12(n)	CF242629.1

About this table Species with no ortholog for USP6

ENSEMBL Gene Tree for USP6

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for USP6 gene

ENSG00000189423² USP21² ENSG00000188933² USP32² USP19²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/228 NCBI SNPs in USP6 are shown (see all 228 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 16)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
--	rs2071456^1,2	A,C,F,H	4972670(+)	`TGCACG/ACATGT`	1	--	ut5¹ ese³		5	EA EU WA	1898
--	rs1122313^1,2	A,C,F,H	4973269(-)	`AGGGAG/AGTCTC`	1	--	ut5¹ ese³		6	EU EA WA MN	2100
--	rs9899177^1,2	A,C,F,H	4999532(+)	`TACCCG/AGAAGA`	1	Q/R	mis¹ ese³ trp³		8	EU EA WA	832
--	rs3887446^1,2	A,C,F,H	4971928(-)	`aaatcG/Agatgg`	1	--	ng5¹		8	MN EU EA WA NA	726
--	rs2071457^1,2	A,C,F,H	4972750(+)	`GACCCA/GGGCAA`	1	--	ut5¹ ese³		5	EA EU WA	1530
	rs3890287^1,2	A,C,F,H	4972892(-)	`GAAAAC/TCTTTG`	1	--	ut5¹ ese³		9	NS EU EA WA	522
	rs8073787^1,2	A,C,F,H	4983618(+)	`TTGAAC/TGGAGC`	1	W/R	mis¹ ese³		8	EU EA WA	834
	rs2309367^1,2	A,C,F,H	5019318(-)	`cgtgcC/Tgctgc`	1	--	ng3¹		5	EU WA NA	382
--	rs3890286^1,2	A,C,F	4973134(-)	`ACATTT/CGGGAA`	1	--	ut5¹ ese³		5	NS	94
--	rs3853647^1,2	A,C,F	4972160(+)	`CTCCCC/ATTGGA`	1	--	ng5¹ tfbs³ trp³		1	MN	184

About this table

HapMap Linkage Disequilibrium images for USP6 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604334

UniProtKB/Swiss-Prot: UBP6_HUMAN, P35125

Involved in tumorigenesis

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/22 PubMed articles for USP6 gene (see all 22 ):

The Tre2 (USP6) oncogene is a hominoid-specific gene. (PubMed id 12604796)^{1, 3, 4} Paulding C.A.... Haber D.A. (2003)
Expression in a RabGAP yeast mutant of two human homologues, one of which is an oncogene. (PubMed id 14521938)^{1, 3, 4} Bizimungu C.... Vandenbol M. (2003)
Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)^{2, 3} Puente X.S.... Lopez-Otin C. (2003)
The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. (PubMed id 8247125)^{3, 4} Papa F.R. and Hochstrasser M. (1993)
De-novo mutation in hereditary motor and sensory neuropathy type I. (PubMed id 1349106)^{2, 3} Hoogendijk J.E....Baas F. (1992)
A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells. (PubMed id 1565468)^{3, 4} Nakamura T.... Hill M. (1992)
USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst. (PubMed id 15026324)^{1, 3} Oliveira A.M.... Fletcher J.A. (2004)
Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. (PubMed id 19077034)³ Ishibashi K.... Fukuda M. (2009)
Frequency of USP6 rearrangements in myositis ossificans, brown tumor, and cherubism: molecular cytogenetic evidence that a subset of "myositis ossificans-like lesions" are the early phases in the formation of soft-tissue aneurysmal bone cyst. (PubMed id 18265974)³ Sukov W.R....Oliveira A.M. (2008)
Mutational analysis of the TRE2 oncogene encoding an inactive RabGAP. (PubMed id 17701273)³ Bizimungu C....Vandenbol M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9098	HGNC: 12629	AceView: USP6	Ensembl:ENSG00000129204	euGenes: HUgn9098
ECgene: USP6	H-InvDB: USP6

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for USP6	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for USP6
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for USP6:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for USP6-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for USP6		Antibodies for USP6
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for USP6		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (USP6)
	Antibodies (USP6)
	Chimera RNAi (USP6)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (USP6)
	Antibodies (USP6)

Search OriGene for USP6

Search Tocris compounds for USP6

	Drugs for USP6
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for USP6

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
USP6 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

USP6 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for USP6

Summaries
for USP6

Genomic Location
for USP6

Proteins
for USP6

Protein Domains/
Families
for USP6

Gene Function
for USP6

Pathways & Interactions
for USP6

Drugs & Compounds
for USP6

Transcripts
for USP6

Expression
for USP6

Orthologs
for USP6

Paralogs
for USP6

SNPs/Variants
for USP6

Disorders & Mutations
for USP6

Medical News
for USP6

Publications
for USP6

Search for USP6

Genome Databases showing USP6

Other Databases showing USP6

Specialized Databases showing USP6

Licensable Technologies
for USP6

Services
for USP6

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

USP6 (Gene Symbol)
EC 3.1.2.15
HRP1
OTTHUMP00000125301
TRE17
TRE2
Tre-2
Tre2
USP6-short
Deubiquitinating enzyme 6
Proto-oncogene TRE-2
Ubiquitin thioesterase 6
Ubiquitin-specific-processing protease 6
hyperpolymorphic gene 1
tre-2 oncogene
ubiquitin specific peptidase 6 (Tre-2 oncogene)
ubiquitin specific peptidase 6-
ubiquitin specific protease 6
ubiquitin specific protease 6 (Tre-2 oncogene)
ubiquitin-specific protease USP6

USP6 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor USP6

Summariesfor USP6

Genomic Locationfor USP6

Proteinsfor USP6

Protein Domains/Familiesfor USP6

Gene Functionfor USP6

Pathways & Interactionsfor USP6

Drugs & Compoundsfor USP6

Transcriptsfor USP6

Expression for USP6

Orthologsfor USP6

Paralogsfor USP6

SNPs/Variantsfor USP6

Disorders & Mutationsfor USP6

Medical Newsfor USP6

Publicationsfor USP6

Search for USP6

Genome Databases showing USP6

Other Databases showing USP6

Specialized Databases showing USP6

Licensable Technologiesfor USP6

Servicesfor USP6

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for USP6

Summaries
for USP6

Genomic Location
for USP6

Proteins
for USP6

Protein Domains/
Families
for USP6

Gene Function
for USP6

Pathways & Interactions
for USP6

Drugs & Compounds
for USP6

Transcripts
for USP6

Expression
for USP6

Orthologs
for USP6

Paralogs
for USP6

SNPs/Variants
for USP6

Disorders & Mutations
for USP6

Medical News
for USP6

Publications
for USP6

Licensable Technologies
for USP6

Services
for USP6