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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

USP49 Gene

protein-coding   GIFtS: 49
GCID: GC06M041787

Ubiquitin Specific Peptidase 49

(Previous name: ubiquitin specific protease 49)
  Search for USP49
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ubiquitin Specific Peptidase 491 2     Ubiquitin Carboxyl-Terminal Hydrolase 492
Ubiquitin Specific Protease 491 2     Ubiquitin Thiolesterase 492
Deubiquitinating Enzyme 492 3     EC 3.4.19.123
Ubiquitin Thioesterase 492 3     EC 3.1.2.158
Ubiquitin-Specific-Processing Protease 492 3     

External Ids:    HGNC: 200781   Entrez Gene: 258622   Ensembl: ENSG000001646637   UniProtKB: Q70CQ13   

Export aliases for USP49 gene to outside databases

Previous GC identifers: GC06M041874 GC06M041919 GC06M041981 GC06M041876 GC06M041762 GC06M041484


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for USP49 Gene: 
USP49 (ubiquitin specific peptidase 49) is a protein-coding gene. GO annotations related to this gene include cysteine-type peptidase activity and ubiquitin thiolesterase activity. An important paralog of this gene is USP3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the USP49 gene promoter:
         Sp1   GCNF   MyoD   NF-kappaB   HNF-1A   FAC1   GCNF-1   HNF-1   NF-kappaB1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUSP49 promoter sequence
   Search SABiosciences Chromatin IP Primers for USP49

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP49


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p12.1

USP49 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USP49 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M041787:  view genomic region     (about GC identifiers)

Start:
41,757,634 bp from pter      End:
41,863,099 bp from pter
Size:
105,466 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UBP49_HUMAN, Q70CQ1 (See protein sequence)
Recommended Name: Ubiquitin carboxyl-terminal hydrolase 49  
Size: 688 amino acids; 79198 Da
Secondary accessions: Q5T3D9 Q5T3E0 Q96CK4
Alternative splicing: 2 isoforms:  Q70CQ1-1   Q70CQ1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for USP49: NX_Q70CQ1

Explore proteomics data for USP49 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q70CQ1

  • 2 DME Specific Peptides for USP49 (Q70CQ1)
     QQDAQEFL  NLGNTCYMN 

    USP49 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    USP49 Protein Expression
    REFSEQ proteins: NP_061031.2  
    ENSEMBL proteins: 
     ENSP00000377797   ENSP00000362101   ENSP00000389842   ENSP00000362097   ENSP00000410003  
     ENSP00000411603   ENSP00000362100   ENSP00000297229  

    Human Recombinant Protein Products for USP49: 
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    OriGene Protein Over-expression Lysate for USP49
    OriGene Custom MassSpec 
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    GenScript Custom Purified and Recombinant Proteins Services for USP49
    Novus Biologicals USP49 Proteins
    Novus Biologicals USP49 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for USP49 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--

    USP49 for ontologies           About GeneDecksing



    USP49 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for USP49 
    Cloud-Clone Corp. CLIAs for USP49


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    USP: Ubiquitin-specific peptidases

    4 InterPro protein domains:
     IPR001394 Peptidase_C19
     IPR001607 Znf_UBP
     IPR018200 Pept_C19ubi-hydrolase_C_CS
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q70CQ1

    ProtoNet protein and cluster: Q70CQ1

    2 Blocks protein domains:
    IPB001394 Ubiquitin thiolesterase
    IPB001607 Zn-finger in ubiquitin thiolesterase


    UniProtKB/Swiss-Prot: UBP49_HUMAN, Q70CQ1
    Similarity: Belongs to the peptidase C19 family
    Similarity: Contains 1 UBP-type zinc finger


    USP49 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UBP49_HUMAN, Q70CQ1
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004197cysteine-type endopeptidase activity IMP--
    GO:0004221ubiquitin thiolesterase activity IDA--
    GO:0004843ubiquitin-specific protease activity IDA--
    GO:0005515protein binding IPI--
    GO:0008234cysteine-type peptidase activity ----
         
    USP49 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for USP49:
     Increased S DNA content  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for USP49 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for USP49

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for USP49 
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    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate USP49 (see all 11):
    hsa-miR-411* hsa-miR-1290 hsa-miR-379* hsa-miR-3138 hsa-miR-3692 hsa-miR-567 hsa-miR-544 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidUSP49 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP49
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP49


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP49

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/47 Interacting proteins for USP49 (Q70CQ13 ENSP000002972294) via UniProtKB, MINT, STRING, and/or I2D (see all 47)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000229802Q925043, ENSP000003917354I2D: score=2 STRING: ENSP00000391735
    SLC39A7Q925043, ENSP000003638074I2D: score=2 STRING: ENSP00000363807
    ENSG00000206288Q925043I2D: score=2 
    ENSG00000224399Q925043I2D: score=2 
    ENSG00000226614Q925043I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IMP--
    GO:0006511ubiquitin-dependent protein catabolic process IEA--
    GO:0035616histone H2B conserved C-terminal lysine deubiquitination IDA--

    USP49 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for USP49 (UBP49)

    Search CenterWatch for drugs/clinical trials and news about USP49 / UBP49

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for USP49 gene: 
    NM_018561.3  

    Unigene Cluster for USP49:

    Ubiquitin specific peptidase 49
    Hs.665742  [show with all ESTs]
    Unigene Representative Sequence: NM_018561
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394253 ENST00000373010 ENST00000448078 ENST00000373006(uc003ori.3)
    ENST00000437061 ENST00000423567 ENST00000373009 ENST00000297229
    miRNA
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    8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate USP49 (see all 11):
    hsa-miR-411* hsa-miR-1290 hsa-miR-379* hsa-miR-3138 hsa-miR-3692 hsa-miR-567 hsa-miR-544 hsa-miR-298
    SwitchGear 3'UTR luciferase reporter plasmidUSP49 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for USP49
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP49
    Clone
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    GenScript: all cDNA clones in your preferred vector: USP49 (NM_018561)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USP49
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP49
    Sirion Biotech Customized lentivirus for stable overexpression of USP49 
                         Customized lentivirus expression plasmids for stable overexpression of USP49 
    Primer
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    OriGene qPCR primer pairs and template standards for USP49
    OriGene qSTAR qPCR primer pairs in human, mouse for USP49
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP49
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP49
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP49

    Additional mRNA sequence: 

    AF119901.2 AJ586139.1 AL049937.1 BC014176.2 

    5 DOTS entries:

    DT.92044269  DT.91742370  DT.102825898  DT.75125613  DT.439199 

    24/226 AceView cDNA sequences (see all 226):

    AA872083 BM770675 BX335588 BM766485 BC014176 BM767313 AF244998 BM770783 
    CA426795 AA878004 AA877415 BM476769 CR603210 BM770564 AI140920 N54253 
    BM768031 BM771474 BM768033 BM768061 BQ670725 BM905102 BQ880980 AA826287 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for USP49    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
    SP1:                                          
    SP2:              -                           


    ECgene alternative splicing isoforms for USP49

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    USP49 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTAAACCCC
    USP49 Expression
    About this image


    See USP49 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for USP49

    SOURCE GeneReport for Unigene cluster: Hs.665742
        SABiosciences Custom PCR Arrays for USP49
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP49

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for USP49 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Usp491 , 5 ubiquitin specific peptidase 491, 5 90.16(n)1
    92.13(a)1
      17 (23.72 cM)5
    2248361  NM_198421.11  NP_940813.11 
     476306905 
    chicken
    (Gallus gallus)
    Aves USP491 ubiquitin specific peptidase 49 75.56(n)
    80.51(a)
      419925  XM_001231681.2  XP_001231682.1 
    lizard
    (Anolis carolinensis)
    Reptilia USP496
    Ubiquitin carboxyl-terminal hydrolase
    74(a)
    1 ↔ 1
    4(119342979-119350503)
    zebrafish
    (Danio rerio)
    Actinopterygii usp491 ubiquitin specific peptidase 49 65.64(n)
    67.06(a)
      559473  NM_001044896.1  NP_001038361.1 
    worm
    (Caenorhabditis elegans)
    Secernentea usp-336
    Protein USP-33
    16(a)
    1 → many
    X(15591368-15595354)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes UBP86
    Ubiquitin-specific protease that is a component of...
    23(a)
    1 → many
    XIII(716715-718130)


    ENSEMBL Gene Tree for USP49 (if available)
    TreeFam Gene Tree for USP49 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for USP49 gene
    USP32  USP442  USP27X2  USP512  USP222  
    1 SIMAP similar gene for USP49 using alignment to 5 protein entries:     UBP49_HUMAN (see all proteins):
    USP44

    USP49 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1810 SNPs in USP49 are shown (see all 1810)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1811380201,2
    --41764889(+) GAGACA/GGGGCT 1 -- int10--------
    rs1839172471,2
    --41764891(+) GACGGA/GGCTTC 1 -- int10--------
    rs1500289601,2
    C--41764980(+) GGCGTA/GAGCCA 1 -- int10--------
    rs1453627381,2
    --41764993(+) GCACCC/TAGCCG 1 -- int10--------
    rs1176505941,2
    C,F--41764997(+) CCAGCC/TGACTG 1 -- int11Minor allele frequency- T:0.04EA 120
    rs1881953211,2
    --41765058(+) GCCTTC/GTAGAA 1 -- int10--------
    rs745251581,2
    F--41765059(+) CCTTCT/CAGAAA 1 -- int12Minor allele frequency- C:0.10CSA WA 120
    rs18914531,2
    C,F,A,H--41765265(+) GTCAGT/CGCAGT 1 -- int118Minor allele frequency- C:0.17NS EA NA 2226
    rs168950201,2
    C,F,H--41765419(+) CTAGTG/AAGATT 1 -- ut31 ese314Minor allele frequency- A:0.02NA NS EA WA 1626
    rs776161801,2
    F--41765571(+) TAACAC/GTGACT 1 -- ut311Minor allele frequency- G:0.01WA 118

    HapMap Linkage Disequilibrium report for USP49 (41757634 - 41863099 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for USP49:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv885833CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing USP49
    DNA2.0 Custom Variant and Variant Library Synthesis for USP49

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    USP49 for disorders           About MalaCards

    USP49 for disorders           About GeneDecksing

    Genetic Association Database (GAD): USP49

    Export disorders for USP49 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for USP49 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with USP49)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. (PubMed id 14715245)1, 2, 3 Quesada V.... Lopez-Otin C. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. (PubMed id 23263863)1 Li J....Sleiman P.M. (2013)
    4. USP49 deubiquitinates histone H2B and regulates cotran scriptional pre-mRNA splicing. (PubMed id 23824326)1 Zhang Z....Wang H. (2013)
    5. Direct and indirect control of mitogen-activated prote in kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/R AF1 kinase, by the deubiquitylating enzyme USP15. (PubMed id 23105109)1 Hayes S.D....Urbe S. (2012)
    6. Genome-wide association study of hematological and bi ochemical traits in a Japanese population. (PubMed id 20139978)1 Kamatani Y....Kamatani N. (2010)
    7. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    10. A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. (PubMed id 14576168)1 Sato S.... Conaway J.W. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25862 HGNC: 20078 AceView: USP49andMGC20741 Ensembl:ENSG00000164663 euGenes: HUgn25862
    ECgene: USP49 H-InvDB: USP49

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for USP49 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for USP49 gene:
    Search GeneIP for patents involving USP49

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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