USP46 Gene
protein-coding GIFtS: 51
GCID: GC04M053376
|
|
ubiquitin specific peptidase 46(Previous name: ubiquitin specific protease 46 )
| |
Aliases
for USP46 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 461 2 | | FLJ125521 | | Ubiquitin Specific Protease 461 2 | | Ubiquitin Carboxyl-Terminal Hydrolase 462 | | Deubiquitinating Enzyme 462 3 | | Ubiquitin Thiolesterase 462 | | Ubiquitin Thioesterase 462 3 | | EC 3.4.19.123 | | Ubiquitin-Specific-Processing Protease 462 3 | | EC 3.1.2.158 |
Export aliases for USP46 gene to outside databasesPrevious GC identifers: GC04M053311 GC04M053302 GC04M053155 GC04M049398 |
Summaries
for USP46 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for USP46:
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinatedaction of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteineproteases that function as deubiquitinating enzymes (Quesada et al., 2004 (PubMed 14715245)).(supplied by OMIM, Jun2009)
UniProtKB/Swiss-Prot: UBP46_HUMAN, P62068Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act bymediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires theinteraction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2
|
Genomic Views
for USP46 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_022853.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the USP46 gene promoter:
S8 AML1a Nkx2-2 Cdc5 POU3F2 YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for USP46
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP46 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q12 Ensembl cytogenetic band: 4q12 HGNC cytogenetic band: 4q12USP46 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M053376: view genomic region
(about GC identifiers)
Start:
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53,457,126 bp from pter |
End:
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53,525,502 bp from pter |
Size:
|
68,377 bases |
Orientation:
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minus strand |
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Proteins
for USP46 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBP46_HUMAN, P62068 (See
protein sequence)Recommended Name: Ubiquitin carboxyl-terminal hydrolase 46 Size: 366 amino acids; 42442 Da
Subunit: Interacts with WDR48
Secondary accessions: B7Z3Y7 B7Z675 B7Z7S3 G8ACC7 Q80V95 Q9H7U4 Q9H9T8Alternative splicing: 4 isoforms: P62068-1 P62068-2 P62068-3 P62068-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for USP46: NX_P62068
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62068
4/17 DME Specific Peptides for USP46 (P62068) (see all 17)
USP46 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001127695.1 NP_073743.2
ENSEMBL proteins: ENSP00000407818 ENSP00000390102 ENSP00000422018 ENSP00000426970 ENSP00000423244 ENSP00000425806
Human Recombinant Protein Products:
USP46 Antibody Products:
Assay Products for USP46: |
Protein
Domains /
Families
for USP46 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP46 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62068ProtoNet protein and cluster: P62068 1 Blocks protein family: IPB001394 Ubiquitin thiolesterase
UniProtKB/Swiss-Prot: UBP46_HUMAN, P62068Similarity: Belongs to the peptidase C19 family. USP12/USP46 subfamily |
Function
for USP46 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBP46_HUMAN, P62068Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act bymediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires theinteraction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): USP46 (NM_001134223) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP46 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP46 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP46 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
USP46 for ontologies About GeneDecksing
Animal Models:
1 MGI mutant phenotype (inferred from 2 alleles ) (MGI details for Usp46):
USP46 for phenotypes About GeneDecksing
|
Pathways & Interactions
for USP46 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitin-Proteasome Dependent Proteolysis | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP46
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP46
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
5/46 Interacting proteins for USP46 (P620683 ENSP000004078184) via UniProtKB, MINT, STRING, and/or I2D (see all 46)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
USP46 for ontologies About GeneDecksing
|
Drugs & Compounds
for USP46 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for USP46
1 HMDB Compound for USP46 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Water | Dihydrogen oxide (see all 2) | 7732-18-5 | -- |
Search CenterWatch for drugs/clinical trials and news about USP46 / UBP46
|
Transcripts
for USP46 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for USP46 gene (2 alternative transcripts): NM_001134223.1 NM_022832.3 Unigene Cluster for USP46: Ubiquitin specific peptidase 46 Hs.7966 [show with all ESTs]Unigene Representative Sequence: NM_0011342239 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000441222(uc003gzm.4 uc003gzn.3 uc011bzr.2 uc011bzs.2)
ENST00000451218 ENST00000503060 ENST00000514536 ENST00000508499 ENST00000502443
ENST00000506707 ENST00000512656 ENST00000504078
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): USP46 (NM_001134223) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP46 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP46 |
Additional cDNA sequence: AF070557.1 AK021861.1 AK022614.1 AK024318.1 AK024345.1 AK096712.1 AK296493.1 AK299883.1 AK302438.1 BC037574.1 GU455414.1 8 DOTS entries: DT.216106 DT.306763 DT.95158698 DT.100009942 DT.121232700 DT.95158700 DT.95215287 DT.87024747 24/144 AceView cDNA sequences (see all 144): BE644658 AI242282 F04866 Z43068 AW511434 BF593826 AU124898 AW051524 CB054693 AW188211 BP371221 CN483539 BF511991 AK024318 AI094585 AU119611 AF070557 AI269069 AL698720 BC037574 AU148675 AA864588 AI087312 AU118910
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for USP46 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for USP46
|
Expression
for USP46 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP46 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTCAGGGAA
About this image
See USP46 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP46
SOURCE GeneReport for Unigene cluster: Hs.7966
UniProtKB/Swiss-Prot: UBP46_HUMAN, P62068Tissue specificity: Broadly expressed
SABiosciences Custom PCR Arrays for USP46
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP46
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP46 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP46 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP46 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP46 |
Orthologs
for USP46 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for USP46 gene from 9/29 species (see all 29) About this table
ENSEMBL Gene Tree for USP46 (if available)
TreeFam Gene Tree for USP46 (if available) |
Paralogs
for USP46 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for USP46 gene
- USP352 USP122 USP382 USP12
1 SIMAP similar gene for USP46 using alignment to 5 protein entries: UBP46_HUMAN (see all proteins):USP12
USP46 for paralogs About GeneDecksing
|
Genomic Variants
for USP46 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Human Gene Mutation Database (HGMD): USP46
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP46 |
|
Disorders
/ Diseases
for USP46 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP46 for disorders About GeneDecksing
OMIM gene information: 612849
OMIM disorders: --
3  diseases for USP46: About MalaCardsmajor depressive disorder bipolar disorder schizophrenia
Human Genome Epidemiology (HuGE) Navigator: USP46 (2 documents)
Export disorders for USP46 gene to outside databases
|
Publications
for USP46 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP46 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with USP46) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Lysine 92 amino acid residue of USP46, a gene associated with 'behavioral despair' in mice, influences the deubiquitinating enzyme activity. (PubMed id 22043315)1, 2 Zhang W....Wang M.W. (2011)
- UAF1 is a subunit of multiple deubiquitinating enzyme complexes. (PubMed id 19075014)1, 2 Cohn M.A.... D'Andrea A.D. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. (PubMed id 14715245)1, 2 Quesada V.... Lopez-Otin C. (2004)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer. (PubMed id 22391563)1 Li X....Gao T. (2013)
- Possible association between ubiquitin-specific pepti dase 46 gene and major depressive disorders in the Japanese population. (PubMed id 21663972)1 Fukuo Y....Iwata N. (2011)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for USP46 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing USP46 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP46 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USP46 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for USP46 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP46 gene:
Search GeneIP for patents involving USP46
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for USP46 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for USP46 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP46 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP46 | | | OriGene Protein Over-expression Lysate for USP46 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for USP46 | | OriGene 3'-UTR Clone for USP46 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP46 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP46 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP46 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP46 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP46 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP46 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP46 |
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 | | | USP46 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP46 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP46 |
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