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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

USP45 Gene

protein-coding GIFtS: 44
GCID: GC06M099925

ubiquitin specific peptidase 45

(Previous name: ubiquitin specific protease 45 )

Search for USP45
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ubiquitin Specific Peptidase 45¹ ²		MGC14793¹
Ubiquitin Specific Protease 45¹ ²		Ubiquitin Carboxyl-Terminal Hydrolase 45²
Deubiquitinating Enzyme 45² ³		Ubiquitin Thiolesterase 45²
Ubiquitin Thioesterase 45² ³		EC 3.4.19.12³
Ubiquitin-Specific-Processing Protease 45² ³		EC 3.1.2.15⁸

External Ids:	HGNC: 20080¹	Entrez Gene: 85015²	Ensembl: ENSG00000123552⁷	UniProtKB: Q70EL2³

Export aliases for USP45 gene to outside databases

Previous GC identifers: GC06M099880 GC06M099987 GC06M097320

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_025741.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the USP45 gene promoter:
ATF-2 CUTL1 POU2F1 POU2F1b POU2F1a FOXO1a c-Jun POU2F1c FOXO1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for USP45

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP45

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16.2 Ensembl cytogenetic band: 6q16.2 HGNC cytogenetic band: 6q16.2

USP45 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USP45 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M099925: view genomic region (about GC identifiers)

Start:	99,880,182 bp from pter	End:	99,969,604 bp from pter
Size:	89,423 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UBP45_HUMAN, Q70EL2 (See protein sequence)

Recommended Name: Ubiquitin carboxyl-terminal hydrolase 45

Size: 814 amino acids; 91733 Da

Sequence caution: Sequence=CAI17192.1; Type=Erroneous gene model prediction; Sequence=CAI19761.1; Type=Erroneous gene

model prediction;

Secondary accessions: B2RXG0 Q5T062 Q86T44 Q86TC0 Q9BRU1

Alternative splicing: 3 isoforms: Q70EL2-1 Q70EL2-2 Q70EL2-3 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for USP45: NX_Q70EL2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q70EL2

4 DME Specific Peptides for USP45 (Q70EL2)

NLGNTCF

WLCLKCG

AYLLFYE

QQQDSQELL

USP45 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001073950.1

ENSEMBL proteins:

ENSP00000424372 ENSP00000421248 ENSP00000333376 ENSP00000358236 ENSP00000422460

ENSP00000423374 ENSP00000421706 ENSP00000425876 ENSP00000330540 ENSP00000423993

ENSP00000426861 ENSP00000376495 ENSP00000439569 ENSP00000358234

Human Recombinant Protein Products for USP45:

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	Uscn Proteins for USP45

USP45 Antibody Products:

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	Novus Biologicals USP45 Antibodies
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Assay Products for USP45:

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	Uscn ELISAs and CLIAs for USP45

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

USP45 for domains About GeneDecksing

4 InterPro domains/families:

IPR001394 Peptidase_C19

IPR001607 Znf_UBP

IPR018200 Pept_C19ubi-hydrolase_C_CS

IPR013083 Znf_RING/FYVE/PHD

Graphical View of Domain Structure for InterPro Entry Q70EL2

ProtoNet protein and cluster: Q70EL2

2 Blocks protein families:

IPB001394 Ubiquitin thiolesterase

IPB001607 Zn-finger in ubiquitin thiolesterase

UniProtKB/Swiss-Prot: UBP45_HUMAN, Q70EL2

Similarity: Belongs to the peptidase C19 family

Similarity: Contains 1 UBP-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: UBP45_HUMAN, Q70EL2

Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the

C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

Enzyme Numbers (IUBMB): EC 3.1.2.15² EC 3.4.19.12¹

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004221	ubiquitin thiolesterase activity	IEA	--
GO:0008234	cysteine-type peptidase activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

USP45 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for USP45:

Increased S DNA content

1 MGI phenotypic allele

for Usp45 (no phenotypes)

USP45 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for USP45

miRNA Products:		OriGene 3'-UTR Clone: USP45 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP45
		8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate USP45 (see all 42):
		hsa-miR-513a-5p hsa-miR-25 hsa-miR-30d hsa-miR-218 hsa-miR-30a hsa-miR-124 hsa-miR-298 hsa-miR-155*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP45 (see all 7) OriGene shRNA RFP: USP45 Browse OriGene siRNA
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		Sirion Biotech Custom design and validation of potent shRNA sequences against USP45

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP45 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP45 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: USP45 (NM_001080481)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP45

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for USP45

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/39 Interacting proteins for USP45 (Q70EL2³ ENSP00000333376⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 39)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
FARS2	O95363³, ENSP00000274680⁴	I2D: score=2 STRING: ENSP00000274680
GLTSCR2	Q9NZM5³, ENSP00000246802⁴	I2D: score=2 STRING: ENSP00000246802
MYH10	P35580³, ENSP00000269243⁴	I2D: score=2 STRING: ENSP00000269243
MYL12B	O14950³, ENSP00000237500⁴	I2D: score=2 STRING: ENSP00000237500
MYL6	P60660³, ENSP00000293422⁴	I2D: score=2 STRING: ENSP00000293422

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006511	ubiquitin-dependent protein catabolic process	IEA	--

USP45 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for USP45
Search CenterWatch for drugs/clinical trials and news about USP45 / UBP45

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for USP45 gene (2 alternative transcripts):

NM_001080481.1 NM_032929.1

Unigene Cluster for USP45:

Ubiquitin specific peptidase 45

Hs.143410 [show with all ESTs]

Unigene Representative Sequence: NM_001080481

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000500704(uc010kcq.2) ENST00000496518 ENST00000327681(uc003ppx.2)

ENST00000369233 ENST00000513344 ENST00000506871 ENST00000511403 ENST00000496090

ENST00000507717 ENST00000329966(uc003pqa.3) ENST00000472914 ENST00000369232

ENST00000508908 ENST00000392738(uc003ppv.2 uc003ppw.2) ENST00000539675

ENST00000369231

miRNA Products:		OriGene 3'-UTR Clone: USP45 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP45
		8/42 QIAGEN miScript miRNA Assays for microRNAs that regulate USP45 (see all 42):
		hsa-miR-513a-5p hsa-miR-25 hsa-miR-30d hsa-miR-218 hsa-miR-30a hsa-miR-124 hsa-miR-298 hsa-miR-155*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP45 (see all 7) OriGene shRNA RFP: USP45 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP45
		Sirion Biotech Custom design and validation of potent shRNA sequences against USP45

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP45 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP45 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP45
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP45

Additional cDNA sequence:

AJ583819.2 AK123299.1 AK310643.1 AL713747.2 AL832030.1 AL832037.1 AL832040.1 BC005991.1

BC150648.2 BC157838.1

14 DOTS entries:

DT.106573 DT.70104415 DT.101961562 DT.121315964 DT.95155699 DT.100035499 DT.91666297 DT.40188681

DT.75110673 DT.100012475 DT.121315875 DT.91700542 DT.91860400 DT.121316063

24/71 AceView cDNA sequences (see all 71):

CR593749 CR625622 AA334141 BU631216 AJ583819 BU618757 CR608058 BQ775514

CD655289 CA427289 CR614890 AI927655 BX423987 AW130352 AI434081 BX481777

BG617247 AL832037 BQ574196 AA307453 AA418449 BI550111 CB114968 BQ229687

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for USP45 About this scheme

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13a	·	13b	^	14	^	15a	·	15b	^	16	^	17a	·	17b
SP1:																			-						-
SP2:			-
SP3:
SP4:
SP5:																																							-

ECgene alternative splicing isoforms for USP45

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

USP45 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CATAATAAAT

About this image
See USP45 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP45

SOURCE GeneReport for Unigene cluster: Hs.143410

UniProtKB/Swiss-Prot: UBP45_HUMAN, Q70EL2

Tissue specificity: Broadly expressed, with highest levels in ovary, skeletal muscle and spleen

SABiosciences Custom PCR Arrays for USP45

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for USP45 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	E1C3M0_CHICK⁶	hypothetical protein LOC421793	67(a)	1 ↔ 1	3(74102771-74156225)
lizard (Anolis carolinensis)	Reptilia	USP45⁶	--	62(a)	1 ↔ 1	1(171747911-171806846)
zebrafish (Danio rerio)	Actinopterygii	LOC564004¹	ubiquitin carboxyl-terminal hydrolase 45-like	58.95(n) 55.98(a)		564004 XM_687364.3 XP_692456.3
fruit fly (Drosophila melanogaster)	Insecta	CG4165¹	CG4165	46.08(n) 38.91(a)		31458 NM_131992.2 NP_572220.1
thale cress (Arabidopsis thaliana)	eudicotyledons	UBP2¹	ubiquitin carboxyl-terminal hydrolase 2	47.45(n) 37.07(a)		839397 NM_100364.3 NP_563719.1
rice (Oryza sativa)	Liliopsida	Os09g0505100¹	hypothetical protein	45.37(n) 34.38(a)		4347503 NM_001070134.1 NP_001063599.1

ENSEMBL Gene Tree for USP45 (if available)
TreeFam Gene Tree for USP45 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for USP45 gene

USP33² USP3² USP44² USP22² USP51² USP16² USP49² USP20²

3 SIMAP similar genes for USP45 using alignment to 11 protein entries: UBP45_HUMAN (see all proteins):

DKFZp313B2010 USP16 USP2

USP45 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs145384627^1,2		--	99879685(+)	`AGACAC/TAAATG`	1	--	ds500¹		0	--	--	--	--
rs148797693^1,2		--	99879718(+)	`TGCTGA/GTGCAA`	1	--	ds500¹		0	--	--	--	--
rs142270926^1,2		--	99879922(+)	`GTTTAC/TGTCCC`	1	--	ds500¹		0	--	--	--	--
rs151258537^1,2		--	99879934(+)	`TACAAC/TATTCA`	1	--	ds500¹		0	--	--	--	--
rs141627389^1,2		--	99879969(+)	`GGAGAC/TAGGGC`	1	--	ds500¹		0	--	--	--	--
rs12605^1,2	C,F	--	99880131(-)	`GCCAGT/CAGACT`	1	--	ds500¹		12		MN NA WA CSA EA	744
rs147054966^1,2		--	99880159(+)	`CCCAGA/CTCCCA`	1	--	ds500¹		0	--	--	--	--
rs192828992^1,2		--	99880274(+)	`CATTCC/TGTCAA`	1	--	ut3¹		0	--	--	--	--
rs137863340^1,2	C	--	99880290(+)	`TAAAC-/TGTGAAA`	1	--	ut3¹		0	--	--	--	--
rs78548969^1,2	C,F	--	99880344(+)	`TATTAT/CGCATG`	1	--	ut3¹		1		WA	118

HapMap Linkage Disequilibrium report for USP45 (99880182 - 99969604 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for USP45: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP45

DNA2.0 Custom Variant and Variant Library Synthesis for USP45

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for USP45 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with USP45)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. (PubMed id 14715245)^{1, 2} Quesada V.... Lopez-Otin C. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)^{1, 3} Puente X.S.... Lopez-Otin C. (2003)
Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)¹ Altun M....Kessler B.M. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)¹ Barrios-Rodiles M....Wrana J.L. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 85015	HGNC: 20080	AceView: USP45	Ensembl:ENSG00000123552	euGenes: HUgn85015
ECgene: USP45	H-InvDB: USP45

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for USP45	Pharmacogenomics, SNPs, Pathways

Intellectual Property for USP45 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for USP45 gene:
Search GeneIP for patents involving USP45

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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USP45 Gene

ubiquitin specific peptidase 45

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USP45 Gene

ubiquitin specific peptidase 45

Aliasesfor USP45 gene

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Functionfor USP45 gene

Pathways & Interactionsfor USP45 gene

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Genome Databases showing USP45 gene

Other Databases showing USP45 gene

Specialized Databases showing USP45 gene

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Productsfor USP45 gene

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Aliases
for USP45 gene

Summaries
for USP45 gene

Genomic Views
for USP45 gene

Proteins
for USP45 gene

Protein Domains /
Families
for USP45 gene

Function
for USP45 gene

Pathways & Interactions
for USP45 gene

Drugs & Compounds
for USP45 gene

Transcripts
for USP45 gene

Expression
for USP45 gene

Orthologs
for USP45 gene

Paralogs
for USP45 gene

Genomic Variants
for USP45 gene

Disorders / Diseases
for USP45 gene

Publications
for USP45 gene

Intellectual Property
for USP45 gene

Products
for USP45 gene