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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

USP42 Gene

protein-coding   GIFtS: 51
GCID: GC07P006144

ubiquitin specific peptidase 42

(Previous name: ubiquitin specific protease 42 )
 Explore 1 disease affiliated with
USP42 via our new
 Human Malady Compendium 
Biological research products
for USP42
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ubiquitin Specific Peptidase 421 2     FLJ126971
Ubiquitin Specific Protease 421 2     Ubiquitin Carboxyl-Terminal Hydrolase 422
Deubiquitinating Enzyme 422 3     Ubiquitin Thiolesterase 422
Ubiquitin Thioesterase 422 3     EC 3.4.19.123
Ubiquitin-Specific-Processing Protease 422 3     EC 3.1.2.158

External Ids:    HGNC: 200681   Entrez Gene: 841322   Ensembl: ENSG000001063467   UniProtKB: Q9H9J43   

Export aliases for USP42 gene to outside databases

Previous GC identifers: GC07P005854 GC07P005895 GC07P005893 GC07P006111 GC07P006022


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: UBP42_HUMAN, Q9H9J4
Function: Deubiquitinating enzyme which may play an important role during spermatogenesis (By similarity)

Gene Wiki entry for USP42


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the USP42 gene promoter:
         Nkx3-1   Nkx3-1 v4   FOXF2   Pax-5   Nkx3-1 v1   Egr-2   Nkx3-1 v2   Nkx3-1 v3   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUSP42 promoter sequence
   Search SABiosciences Chromatin IP Primers for USP42

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP42


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1   Ensembl cytogenetic band:  7p22.1   HGNC cytogenetic band: 7p22.2

USP42 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USP42 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P006144:  view genomic region     (about GC identifiers)

Start:
6,144,515 bp from pter      End:
6,201,195 bp from pter
Size:
56,681 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 6,190,906-6,247,551     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UBP42_HUMAN, Q9H9J4 (See protein sequence)
Recommended Name: Ubiquitin carboxyl-terminal hydrolase 42  
Size: 1324 amino acids; 145392 Da
Secondary accessions: A2RUE3 B5MDA5 Q0VIN8 Q3C166 Q6P9B4
Alternative splicing: 2 isoforms:  Q9H9J4-1   Q9H9J4-2   

Explore the universe of human proteins at neXtProt for USP42: NX_Q9H9J4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H9J4

  • 4/7 DME Specific Peptides for USP42 (Q9H9J4) (see all 7)
     NLGNTCF  FIGPQLP  CTMQAHIT  VYVLYAVLVH 

    USP42 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_115548.1  
    ENSEMBL proteins: 
     ENSP00000301962   ENSP00000385964   ENSP00000416910   ENSP00000430568   ENSP00000431127  
     ENSP00000408217  

    Human Recombinant Protein Products: 
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    Novus Biologicals USP42 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for USP42


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    Uscn Antibodies for USP42
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    Uscn ELISAs and CLIAs for USP42


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    USP42 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001394 Peptidase_C19
     IPR018200 Pept_C19ubi-hydrolase_C_CS

    Graphical View of Domain Structure for InterPro Entry Q9H9J4

    ProtoNet protein and cluster: Q9H9J4

    1 Blocks protein family: IPB001394 Ubiquitin thiolesterase

    UniProtKB/Swiss-Prot: UBP42_HUMAN, Q9H9J4
    Similarity: Belongs to the peptidase C19 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: UBP42_HUMAN, Q9H9J4
    Function: Deubiquitinating enzyme which may play an important role during spermatogenesis (By similarity)
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the
    C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

    Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121

    miRNA
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    OriGene 3'-UTR Clone: USP42
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP42
    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate USP42 (see all 59):
    hsa-miR-194* hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-15a hsa-miR-128 hsa-miR-29a hsa-miR-16-1*
    SwitchGear 3'UTR luciferase reporter plasmidUSP42 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP42 (see all 7)
    OriGene shRNA RFP: USP42
    OriGene siRNA: USP42
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP42

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for USP42

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP42 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP42

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004221ubiquitin thiolesterase activity IEA--
    GO:0008234cysteine-type peptidase activity IEA--


    USP42 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for USP42:
     Decreased influenza A/WSN/33 r 

    Animal Models:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Usp42):
     behavior/neurological  hematopoietic system  immune system  reproductive system  vision/eye 

    USP42 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Ubiquitin-Proteasome Dependent Proteolysis
    Ubiquitin-Proteasome Dependent Proteolysis1.00

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP42
        Ubiquitin-Proteasome Dependent Proteolysis


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP42

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/100 Interacting proteins for USP42 (Q9H9J42, 3 ENSP000003019624) via UniProtKB, MINT, STRING, and/or I2D (see all 100)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TP53P046372, 3, ENSP000002693054MINT-8303846 MINT-8303829 I2D: score=1 STRING: ENSP00000269305
    YWHAQP273482, 3, ENSP000002380814MINT-7899812 I2D: score=1 STRING: ENSP00000238081
    CA2P009183, ENSP000002853794I2D: score=2 STRING: ENSP00000285379
    HERC2O957143, ENSP000002616094I2D: score=2 STRING: ENSP00000261609
    LRRC47Q8N1G43, ENSP000003674984I2D: score=2 STRING: ENSP00000367498
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006511ubiquitin-dependent protein catabolic process IEA--
    GO:0007283spermatogenesis IEA--
    GO:0016579protein deubiquitination ISS--
    GO:0030154cell differentiation IEA--


    USP42 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for USP42

    1 HMDB Compound for USP42    About this table
    CompoundSynonyms CAS #PubMed Ids
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about USP42 / UBP42 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for USP42 gene: 
    NM_032172.2  

    Unigene Cluster for USP42:

    Ubiquitin specific peptidase 42
    Hs.31856  [show with all ESTs]
    Unigene Representative Sequence: NM_032172
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306177(uc010kth.1 uc011jwp.2) ENST00000404008(uc011jwn.1)
    ENST00000479544(uc011jwo.1) ENST00000451154 ENST00000465073 ENST00000521713(uc011jwq.2)
    ENST00000426246(uc011jwr.1)

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: USP42
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP42
    8/59 QIAGEN miScript miRNA Assays for microRNAs that regulate USP42 (see all 59):
    hsa-miR-194* hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-15a hsa-miR-128 hsa-miR-29a hsa-miR-16-1*
    SwitchGear 3'UTR luciferase reporter plasmidUSP42 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP42 (see all 7)
    OriGene shRNA RFP: USP42
    OriGene siRNA: USP42
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP42
    Clone
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    GenScript: all cDNA clones in your preferred vector: USP42 (NM_032172)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USP42
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP42 
    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP42
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP42
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP42
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP42

    Additional cDNA sequence: 

    AJ601395.1 AK022759.1 AK298164.1 AK301527.1 AK309375.1 AY618868.1 BC060846.1 BC132862.1 
    BC136656.1 

    12 DOTS entries:

    DT.100784607  DT.87018386  DT.453542  DT.121099480  DT.100035427  DT.100784609  DT.101959112  DT.121099479 
    DT.121099499  DT.40239023  DT.102829219  DT.99950401 

    24/211 AceView cDNA sequences (see all 211):

    BE219034 BM708574 AI936218 AI458057 AI916527 CA436584 CA844306 AI299688 
    BX418055 BM980885 BU195574 AW594202 CA312336 BM995466 BF195598 AA936550 
    AW575816 AI024619 BU173371 BX354198 BC060846 AI081335 AU130866 AI202031 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    USP42 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAAAATTTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See USP42 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for USP42

    SOURCE GeneReport for Unigene cluster: Hs.31856

    UniProtKB/Swiss-Prot: UBP42_HUMAN, Q9H9J4
    Tissue specificity: Broadly expressed

        SABiosciences Custom PCR Arrays for USP42
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP42

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for USP42 gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves USP421 ubiquitin specific peptidase 42 56.17(n)
    48.04(a)
      416431  XM_414742.3  XP_414742.3 
    lizard
    (Anolis carolinensis)
    Reptilia USP426
    --
    53(a)
    1 → many
    GL343507.1(184980-198082)
    zebrafish
    (Danio rerio)
    Actinopterygii wufi15g042 Danio rerio, Similar to KIAA1453 protein, clone IMAGE26 more 79.09(n)    BC057482.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta scny6
    scrawny
    14(a)
    possible ortholog
    3L(5762223-5769371)
    worm
    (Caenorhabditis elegans)
    Secernentea T22F3.26
    Protein T22F3.2, isoform b
    19(a)
    possible ortholog
    V(3586637-3589004)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons UBP181 ubiquitin carboxyl-terminal hydrolase 18 52.28(n)
    42.24(a)
      829295  NM_119316.4  NP_194895.1 
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 4)
    ubiquitin carboxyl-terminal hydrolase domain conta...
    ubiquitin carboxyl-terminal hydrolase domain conta...
    (see all 4)
    18(a)
    15(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    6(4212120-4217604)
    2(33791497-33797995)


    ENSEMBL Gene Tree for USP42 (if available)
    TreeFam Gene Tree for USP42 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for USP42 gene
    USP17L132  USP17L282  USP17L242  USP17L302  USP17L122  USP17L172  USP17L262  USP17L232  
    USP17L182  USP17L252  USP82  USP17L152  USP17L212  USP17L202  USP17L192  USP17L102  
    USP22  USP17L272  USP362  USP212  USP17L222  USP17L52  USP17L22  USP17L292  
    USP17L112  USP502  
    13 SIMAP similar genes for USP42 using alignment to 8 protein entries:     UBP42_HUMAN (see all proteins):
    USP17L6    DUB1    USP17L3    USP17L1P    USP17L5    USP17L4
    USP17L7    USP17L2    USP17L8    USP36    USP17L13    USP3
    DKFZp434K1822

    USP42 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1155 NCBI SNPs in USP42 are shown (see all 1155    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1482160241,2
    --6142595(+) GGTCAA/GGACAG 1 -- us2k10--------
    rs1140865941,2
    C,F,--6142691(+) GTCTGG/ATGAGC 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs283735551,2
    C,--6142729(+) AGGGAG/AAAGCA 1 -- us2k14Minor allele frequency- A:0.14NA WA 124
    rs796076701,2
    F,--6142878(+) TGCTAG/AGATTT 1 -- us2k11Minor allele frequency- A:0.04NA 120
    rs1173308631,2
    --6142899(+) CTGGAC/TGGGGT 1 -- us2k11Minor allele frequency- T:0.01EA 120
    rs1179494061,2
    F,--6142913(+) CAGGGG/ATCTAT 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1809924061,2
    --6142996(+) AACTCC/TGTCTC 1 -- us2k10--------
    rs1148631861,2
    --6143002(+) GTCTCT/CACAAA 1 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1858700951,2
    --6143024(+) TAGCCA/GGGCGT 1 -- us2k10--------
    rs1402433201,2
    --6143042(+) GGCATC/GTGTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for USP42 (6144515 - 6201195 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for USP42
         5 CNVs: 10174 94359 36692 94361 64747
         1 Inversion: 37290

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP42
    DNA2.0 Custom Variant and Variant Library Synthesis for USP42

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    USP42 for disorders           About GeneDecksing

    1 disease for USP42:    About MalaCards
    myelodysplastic syndrome


    Export disorders for USP42 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for USP42 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with USP42)
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    1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. (PubMed id 14715245)1, 2 Quesada V.... Lopez-Otin C. (2004)
    5. Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
    6. A yeast two-hybrid screen reveals that osteopontin ass ociates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (2012)
    7. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    8. Regulation of p53 stability and function by the deubi quitinating enzyme USP42. (PubMed id 22085928)1 Hock A.K....Vousden K.H. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84132 HGNC: 20068 AceView: USP42 Ensembl:ENSG00000106346 euGenes: HUgn84132
    ECgene: USP42 H-InvDB: USP42

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for USP42 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for USP42 gene:
    Search GeneIP for patents involving USP42

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