Aliases for USP39 Gene
External Ids for USP39 Gene
Previous GeneCards Identifiers for USP39 Gene
GeneCards Summary for USP39 Gene
USP39 (Ubiquitin Specific Peptidase 39) is a Protein Coding gene. Diseases associated with USP39 include agoraphobia and generalized anxiety disorder. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis and Spliceosome. GO annotations related to this gene include ubiquitin thiolesterase activity.
UniProtKB/Swiss-Prot for USP39 Gene
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs).