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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

USP31 Gene

protein-coding   GIFtS: 50
GCID: GC16M022986

Ubiquitin Specific Peptidase 31

(Previous name: ubiquitin specific protease 31)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ubiquitin Specific Peptidase 311 2     Ubiquitin Specific Proteinase 312
Ubiquitin Specific Protease 311 2     Ubiquitin Thiolesterase 312
Deubiquitinating Enzyme 312 3     EC 3.4.19.123
Ubiquitin Thioesterase 312 3     KIAA12033
Ubiquitin-Specific-Processing Protease 312 3     EC 3.1.2.158
Ubiquitin Carboxyl-Terminal Hydrolase 312     

External Ids:    HGNC: 200601   Entrez Gene: 574782   Ensembl: ENSG000001034047   UniProtKB: Q70CQ43   

Export aliases for USP31 gene to outside databases

Previous GC identifers: GC01M021151 GC01M021474 GC16M023045 GC16M021162


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for USP31 Gene: 
USP31 (ubiquitin specific peptidase 31) is a protein-coding gene. Diseases associated with USP31 include gastric cancer. GO annotations related to this gene include cysteine-type peptidase activity and ubiquitin thiolesterase activity. An important paralog of this gene is USP45.

UniProtKB/Swiss-Prot: UBP31_HUMAN, Q70CQ4
Function: May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the
processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010393.16  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the USP31 gene promoter:
         SREBP-1c   Pax-2   Nkx2-5   AP-4   SREBP-1b   Meis-1b   SREBP-1a   Meis-1a   NF-kappaB1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUSP31 promoter sequence
   Search SABiosciences Chromatin IP Primers for USP31

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2   Ensembl cytogenetic band:  16p12.2   HGNC cytogenetic band: 16p12.3

USP31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USP31 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M022986:  view genomic region     (about GC identifiers)

Start:
23,072,727 bp from pter      End:
23,160,591 bp from pter
Size:
87,865 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UBP31_HUMAN, Q70CQ4 (See protein sequence)
Recommended Name: Ubiquitin carboxyl-terminal hydrolase 31  
Size: 1352 amino acids; 146651 Da
Sequence caution: Sequence=AK126752; Type=Frameshift; Positions=941;
Secondary accessions: Q6AW97 Q6ZTC0 Q6ZTN2 Q9ULL7
Alternative splicing: 2 isoforms:  Q70CQ4-1   Q70CQ4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for USP31: NX_Q70CQ4

Explore proteomics data for USP31 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q70CQ4

  • 2 DME Specific Peptides for USP31 (Q70CQ4)
     LIIHLKR  GNTCFMN 

    USP31 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    USP31 Protein Expression
    REFSEQ proteins: NP_065769.3  
    ENSEMBL proteins: 
     ENSP00000219689   ENSP00000461621  

    Human Recombinant Protein Products for USP31: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for USP31
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for USP31
    GenScript Custom Purified and Recombinant Proteins Services for USP31
    Novus Biologicals USP31 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for USP31 


    USP31 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals USP31 Antibodies
    Abcam antibodies for USP31
    Cloud-Clone Corp. Antibodies for USP31 
    Search ThermoFisher Antibodies for USP31
    LSBio Antibodies in human, mouse, rat for USP31 

    Assay Products for USP31: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for USP31
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for USP31 
    Cloud-Clone Corp. CLIAs for USP31


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    USP: Ubiquitin-specific peptidases

    2 InterPro protein domains:
     IPR001394 Peptidase_C19
     IPR018200 Pept_C19ubi-hydrolase_C_CS

    Graphical View of Domain Structure for InterPro Entry Q70CQ4

    ProtoNet protein and cluster: Q70CQ4

    1 Blocks protein domain: IPB001394 Ubiquitin thiolesterase

    UniProtKB/Swiss-Prot: UBP31_HUMAN, Q70CQ4
    Similarity: Belongs to the peptidase C19 family


    USP31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UBP31_HUMAN, Q70CQ4
    Function: May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the
    processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity)
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004221ubiquitin thiolesterase activity IEA--
    GO:0008234cysteine-type peptidase activity IEA--
         
    USP31 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for USP31:
     G2 arrest  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for USP31 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for USP31

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for USP31 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for USP31 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP31
    8/115 QIAGEN miScript miRNA Assays for microRNAs that regulate USP31 (see all 115):
    hsa-miR-124* hsa-miR-15a hsa-miR-106a hsa-miR-218-1* hsa-miR-938 hsa-miR-519a hsa-miR-4325 hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for USP31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP31

    Gene Editing
    Products:
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    Sirion Biotech Customized adenovirus for overexpression of USP31

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for USP31 (see all 5)
    OriGene ORF clones in mouse, rat for USP31
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: USP31 (NM_020718)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USP31
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP31
    Sirion Biotech Customized lentivirus for stable overexpression of USP31 
                         Customized lentivirus expression plasmids for stable overexpression of USP31 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for USP31
    Search LifeMap BioReagents cell lines for USP31
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP31


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for USP31 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ubiquitin-Proteasome Dependent Proteolysis
    Ubiquitin-Proteasome Dependent Proteolysis

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP31
        Ubiquitin-Proteasome Dependent Proteolysis


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for USP31

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for USP31 (Q70CQ43 ENSP000002196894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RELAQ042063, ENSP000003842734I2D: score=1 STRING: ENSP00000384273
    TRAF2Q129333, ENSP000002476684I2D: score=1 STRING: ENSP00000247668
    USP21ENSP000002898654STRING: ENSP00000289865
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006511ubiquitin-dependent protein catabolic process IEA--

    USP31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for USP31 (UBP31)

    Search CenterWatch for drugs/clinical trials and news about USP31 / UBP31

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for USP31 gene: 
    NM_020718.3  

    Unigene Cluster for USP31:

    Ubiquitin specific peptidase 31
    Hs.183817  [show with all ESTs]
    Unigene Representative Sequence: NM_020718
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000219689(uc002dlk.3 uc010vca.2 uc010bxm.3 uc002dll.3)
    ENST00000567975 ENST00000381162 ENST00000563525
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USP31
    8/115 QIAGEN miScript miRNA Assays for microRNAs that regulate USP31 (see all 115):
    hsa-miR-124* hsa-miR-15a hsa-miR-106a hsa-miR-218-1* hsa-miR-938 hsa-miR-519a hsa-miR-4325 hsa-miR-93
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for USP31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP31
    Clone
    Products:
         
    OriGene clones in human, mouse for USP31 (see all 5)
    OriGene ORF clones in mouse, rat for USP31
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: USP31 (NM_020718)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USP31
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP31
    Sirion Biotech Customized lentivirus for stable overexpression of USP31 
                         Customized lentivirus expression plasmids for stable overexpression of USP31 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for USP31
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP31
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP31
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP31

    Additional mRNA sequence: 

    AB033029.1 AJ586135.2 AK057491.1 AK092790.1 AK126752.1 U52050.1 

    5 DOTS entries:

    DT.101980244  DT.91901673  DT.92425946  DT.99928034  DT.95129569 

    24/159 AceView cDNA sequences (see all 159):

    AL599357 BF512220 F10465 BQ050792 CD246092 CB242222 AI342753 H82214 
    AW440572 AI187852 AV725025 AI693630 AI168312 AA995097 AJ586135 BF939930 
    BX115399 BM718012 AV725490 BU683258 AI783638 F12863 BQ948537 BX648357 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    USP31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGATGTGTCA
    USP31 Expression
    About this image


    See USP31 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for USP31

    SOURCE GeneReport for Unigene cluster: Hs.183817

    UniProtKB/Swiss-Prot: UBP31_HUMAN, Q70CQ4
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for USP31
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for USP31
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP31
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for USP31 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Usp311 , 5 ubiquitin specific peptidase 311, 5 87.92(n)1
    92.1(a)1
      7 (65.07 cM)5
    761791  NM_001033173.11  NP_001028345.11 
     1216420215 
    chicken
    (Gallus gallus)
    Aves USP311 ubiquitin specific peptidase 31 74.64(n)
    78.19(a)
      416580  XM_003642146.1  XP_003642194.1 
    lizard
    (Anolis carolinensis)
    Reptilia USP316
    Ubiquitin carboxyl-terminal hydrolase
    67(a)
    1 ↔ 1
    GL343936.1(57174-102118)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.328512 Xenopus laevis transcribed sequence with weak similarity more 76.79(n)    BJ627030.1 
    zebrafish
    (Danio rerio)
    Actinopterygii usp311 ubiquitin specific peptidase 31 63.38(n)
    63.22(a)
      564487  XM_687820.5  XP_692912.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG304216
    --
    25(a)
    1 → many
    2R(20631335-20644501)


    ENSEMBL Gene Tree for USP31 (if available)
    TreeFam Gene Tree for USP31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for USP31 gene
    USP452  USP192  USP62  USP152  USP162  USP112  USP432  USP322  
    USP42  
    3 SIMAP similar genes for USP31 using alignment to 2 protein entries:     UBP31_HUMAN (see all proteins):
    USP15    USP43    USP11

    USP31 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1806 SNPs in USP31 are shown (see all 1806)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1863260561,2
    --23072252(+) TCAGTA/TGGGAG 1 -- ds50010--------
    rs1161654801,2
    C,F--23072272(+) GAAGGG/ATGGGA 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1912722651,2
    --23072686(+) ACCAAA/GAAGAT 1 -- ds50010--------
    rs1826779421,2
    --23072693(+) AGATAA/TCAGTT 1 -- ds50010--------
    rs1867370491,2
    --23072694(+) GATATC/TAGTTG 1 -- ds50010--------
    rs1899650001,2
    --23072779(+) CCACTC/TTTCTC 1 -- ut310--------
    rs1404809151,2
    C--23072780(+) CACTT-/TTCTC 
            
    TTAAT
    1 -- ut310--------
    rs768888921,2
    C--23072803(+) TATACC/TATATA 1 -- ut310--------
    rs791569981,2
    C--23072804(+) ATACTA/CTATAA 1 -- ut310--------
    rs1473117501,2
    C--23072805(+) TACTAC/TATAAT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for USP31 (23072727 - 23160591 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for USP31:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv23899CNV Loss19812545
    nsv521703CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing USP31
    DNA2.0 Custom Variant and Variant Library Synthesis for USP31

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for USP31:    About MalaCards
    gastric cancer    


    USP31 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: USP31 (1 document)

    Export disorders for USP31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for USP31 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with USP31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. (PubMed id 14715245)1, 2 Quesada V.... Lopez-Otin C. (2004)
    3. Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
    4. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (1999)
    5. Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB. (PubMed id 16214042)1, 9 Tzimas C....Hatzivassiliou E.G. (2006)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    8. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
    9. Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis. (PubMed id 15354349)1 Lockhart P.J.... Farrer M.J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57478 HGNC: 20060 AceView: USP31 Ensembl:ENSG00000103404 euGenes: HUgn57478
    ECgene: USP31 H-InvDB: USP31

    (According to HUGE)
    About This Section
    HUGE: KIAA1203

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for USP31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for USP31 gene:
    Search GeneIP for patents involving USP31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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