USP3 Gene
protein-coding GIFtS: 53
GCID: GC15P063796
|
|
ubiquitin specific peptidase 3(Previous name: ubiquitin specific protease 3 )
| |
Aliases
for USP3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 31 2 | | UBP2 | | Deubiquitinating Enzyme 32 3 | | Ubiquitin Carboxyl-Terminal Hydrolase 32 | | Ubiquitin Thioesterase 32 3 | | Ubiquitin Thiolesterase 32 | | Ubiquitin-Specific-Processing Protease 32 3 | | EC 3.4.19.123 | | Ubiquitin Specific Protease 31 | | EC 3.1.2.158 | | SIH0032 | | |
Export aliases for USP3 gene to outside databasesPrevious GC identifers: GC15P059583 GC15P056887 GC15P061375 GC15P061512 GC15P061511 GC15P061582 GC15P040621 |
Summaries
for USP3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: UBP3_HUMAN, Q9Y6I4Function: Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required forproper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpointthrough deubiquitination of H2A at DNA damage sites. Associates with the chromatin
|
Genomic Views
for USP3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the USP3 gene promoter:
AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for USP3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q22.3 Ensembl cytogenetic band: 15q22.31 HGNC cytogenetic band: 15q22.3USP3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P063796: view genomic region
(about GC identifiers)
Start:
|
63,796,793 bp from pter |
End:
|
63,886,839 bp from pter |
Size:
|
90,047 bases |
Orientation:
|
plus strand |
|
Proteins
for USP3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBP3_HUMAN, Q9Y6I4 (See
protein sequence)Recommended Name: Ubiquitin carboxyl-terminal hydrolase 3 Size: 520 amino acids; 58897 Da
Subunit: Interacts (via UBP-type domain) with H2A; the interaction is less efficient than with monoubiquitinated H2A
Subcellular location: Nucleus. Note=Localizes preferentially with monoubiquitinated H2A to chromatin
Sequence caution: Sequence=AAD42992.1; Type=Frameshift; Positions=265, 274, 299;
Secondary accessions: B4DVU5 F5H1A6 Q8WVD0Alternative splicing: 2 isoforms: Q9Y6I4-1 Q9Y6I4-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for USP3: NX_Q9Y6I4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y6I4
4 DME Specific Peptides for USP3 (Q9Y6I4)
USP3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001243631.1 NP_006528.2
ENSEMBL proteins: ENSP00000453688 ENSP00000453194 ENSP00000369681 ENSP00000454043 ENSP00000452929 ENSP00000453767 ENSP00000453228 ENSP00000453093 ENSP00000454197 ENSP00000453619 ENSP00000452947 ENSP00000445793 ENSP00000453138 ENSP00000453489 ENSP00000445828 ENSP00000445615 ENSP00000268049 ENSP00000445642
Human Recombinant Protein Products for USP3:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
USP3 for ontologies About GeneDecksing
USP3 Antibody Products:
Assay Products for USP3: |
Protein
Domains /
Families
for USP3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y6I4ProtoNet protein and cluster: Q9Y6I4 2 Blocks protein families: IPB001394 Ubiquitin thiolesterase IPB001607 Zn-finger in ubiquitin thiolesterase
UniProtKB/Swiss-Prot: UBP3_HUMAN, Q9Y6I4Domain: Both protease activity and an intact zinc finger are required for H2A monodeubiquitinationSimilarity: Belongs to the peptidase C19 family. USP3 subfamilySimilarity: Contains 1 UBP-type zinc finger |
Function
for USP3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UBP3_HUMAN, Q9Y6I4Function: Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required forproper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpointthrough deubiquitination of H2A at DNA damage sites. Associates with the chromatinCatalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Genatlas biochemistry entry for USP3:ubiquitin specific protease 3,with two transcripts,both widely expressed at a low level and highly expressed inpancreas,cleaving a ubiquitin-proline bond,deubiquitin enzyme family
Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
USP3 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: USP3 (NM_004090) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP3 |
|
Pathways & Interactions
for USP3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitin-Proteasome Dependent Proteolysis | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP3
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 23)
5/27 Interacting proteins for USP3 (Q9Y6I43 ENSP000003696814) via UniProtKB, MINT, STRING, and/or I2D (see all 27)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
USP3 for ontologies About GeneDecksing
|
Drugs & Compounds
for USP3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for USP3
1 HMDB Compound for USP3 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Water | Dihydrogen oxide (see all 2) | 7732-18-5 | -- |
Search CenterWatch for drugs/clinical trials and news about USP3 / UBP3
|
Transcripts
for USP3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for USP3 gene (2 alternative transcripts): NM_001256702.1 NM_006537.3 Unigene Cluster for USP3: Ubiquitin specific peptidase 3 Hs.458499 [show with all ESTs]Unigene Representative Sequence: NR_04634118/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000561442 ENST00000560070 ENST00000380324(uc010uii.1 uc002amf.3 uc002amg.3 uc010uij.2 uc010uik.2 uc010bgs.3)
ENST00000557884 ENST00000558157 ENST00000561326 ENST00000559873 ENST00000559192
ENST00000559771 ENST00000559276 ENST00000558285 ENST00000559257 ENST00000538686(uc002ami.3)
ENST00000559711 ENST00000558925 ENST00000558218 ENST00000561381 ENST00000559718
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: USP3 (NM_004090) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP3 |
Additional cDNA sequence: AF073344.1 AF077040.1 AK022931.1 AK094444.1 AK300948.1 AK301236.1 AK301563.1 AK307810.1 AK309382.1 AK314223.1 AY461579.1 BC018113.2 BC065300.1 BC100029.1 BC107137.1 BC107138.1 BT007269.1 BX647760.1 NR_046341.1 NR_046342.1 24 DOTS entries: DT.427727 DT.213931 DT.86853868 DT.91914274 DT.100798066 DT.91993798 DT.92027113 DT.100008322 DT.121069165 DT.92409463 DT.95082713 DT.97829482 DT.100689433 DT.121069083 DT.121069107 DT.121069145 DT.40132237 DT.86857742 DT.95082709 DT.97841560 DT.40117767 DT.40305161 DT.75162765 DT.97841559 24/230 AceView cDNA sequences (see all 230): CD369463 BI770143 CA489578 CB159645 AI291397 AU142702 C05514 AI334394 BE503404 AA830044 BM788363 AA906958 AY461579 BU188287 Z39017 BG503991 T10839 AA935853 AW467585 BQ109158 AA312257 BG944820 BC018113 AI368920
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for USP3 (see all 14) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17b | ^ | 18a | · | 18b | ^ | 19 | ^ | 20a | · | 20b | · | 20c | · | 20d |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for USP3
|
Expression
for USP3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTGCACAAT
About this image
See USP3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP3
SOURCE GeneReport for Unigene cluster: Hs.458499
UniProtKB/Swiss-Prot: UBP3_HUMAN, Q9Y6I4Tissue specificity: Expressed in all tissues examined, with strongest expression in pancreas
SABiosciences Expression via Pathway-Focused PCR Array including USP3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP3 |
Orthologs
for USP3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for USP3 gene from 6/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
USP31 |
ubiquitin specific peptidase 3 |
86.79(n)
95.77(a) |
|
415369 XM_413755.3 XP_413755.3 |
lizard
(Anolis carolinensis) |
Reptilia |
USP36 |
-- |
88(a) |
1 ↔ 1 |
GL343573.1(4335-15524) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.154902 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.42(n) |
|
BU906546.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufe50h062 |
Danio rerio cDNA clone IMAGE5915429, partial cds |
77.05(n) |
|
BC059202.1 |
mosquito
(Anopheles gambiae) |
Insecta |
AgaP_AGAP0088051 |
AGAP008805-PA |
52.53(n)
50(a) |
|
1275662 XM_314931.4 XP_314931.4 |
worm
(Caenorhabditis elegans) |
Secernentea |
usp-31 |
Protein USP-3 |
49.44(n)
42.42(a) |
|
190579 NM_061033.2 NP_493434.2 |
ENSEMBL Gene Tree for USP3 (if available)
TreeFam Gene Tree for USP3 (if available) |
Paralogs
for USP3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for USP3 gene
- USP332 USP442 USP162 USP452 USP512 USP222 USP492 USP202
16 SIMAP similar genes for USP3 using alignment to 16 protein entries: UBP3_HUMAN (see all proteins):USP15 BRAP USP48 USP4 USP33 HDAC6
USP36 USP17L13 USP42 USP8 USP39 USP44
USP19 USP2 USP11 USP12
USP3 for paralogs About GeneDecksing
|
Genomic Variants
for USP3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for USP3 (63796793 - 63886839 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for USP3
1 CNV: 87707 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP3 |
|
Disorders
/ Diseases
for USP3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP3 for disorders About GeneDecksing
OMIM gene information: 604728
OMIM disorders: --
1  disease for USP3: About MalaCardsmalaria
Human Genome Epidemiology (HuGE) Navigator: USP3 (2 documents)
Export disorders for USP3 gene to outside databases
|
Publications
for USP3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP3 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with USP3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization and chromosomal localization of USP3, a novel human ubiquitin-specific protease. (PubMed id 10480896)1, 2, 9 Sloper-Mould K.E.... Baker R.T. (1999)
- Human USP3 is a chromatin modifier required for S phase progression and genome stability. (PubMed id 17980597)1, 2 Nicassio F....Citterio E. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- UCP3 polymorphisms, hand grip performance and survival at old age: association analysis in two Danish middle aged and elderly cohorts. (PubMed id 22743239)1 Dato S....Christiansen L. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for USP3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing USP3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USP3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for USP3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP3 gene:
Search GeneIP for patents involving USP3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for USP3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for USP3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP3 | | | OriGene Protein Over-expression Lysate for USP3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for USP3 | | OriGene 3'-UTR Clone for USP3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for USP3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for USP3 | | OriGene Custom Protein Services for USP3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP3 |
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| | | | Search Tocris compounds for USP3 |
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 | | | USP3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP3 |
|  |  |  |  | | | | ThermoFisher Antibodies for USP3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP3 |
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