USP22 Gene
protein-coding GIFtS: 55
GCID: GC17M020902
|
|
ubiquitin specific peptidase 22(Previous names: ubiquitin specific protease 22, ubiquitin specific peptidase...)
(Previous symbol: USP3L)
| |
Aliases
for USP22 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 221 2 | | Ubiquitin Specific Peptidase 3-Like1 | | USP3L1 2 3 | | Ubiquitin Carboxyl-Terminal Hydrolase 222 | | Ubiquitin Specific Protease 221 2 | | Ubiquitin Thiolesterase 222 | | KIAA10631 3 | | Ubiquitin-Specific Processing Protease 222 | | Deubiquitinating Enzyme 222 3 | | EC 3.4.19.123 | | Ubiquitin Thioesterase 222 3 | | KIAA10645 | | Ubiquitin-Specific-Processing Protease 222 3 | | EC 3.1.2.158 |
Export aliases for USP22 gene to outside databasesPrevious GC identifers: GC17P020956 GC17M022551 GC17M020808 GC17M021064 GC17M020843 GC17M020106 |
Summaries
for USP22 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: UBP22_HUMAN, Q9UPT9Function: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specificgene promoters by activators such as MYC, where it is required for transcription. Required for nuclearreceptor-mediated transactivation and cell cycle progression
|
Genomic Views
for USP22 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the USP22 gene promoter:
AP-2rep Pax-5 ATF-2 LCR-F1 E47 YY1 AREB6 CREB CRE-BP1 deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for USP22
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP22 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2USP22 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M020902: view genomic region
(about GC identifiers)
Start:
|
20,902,906 bp from pter |
End:
|
20,947,073 bp from pter |
Size:
|
44,168 bases |
Orientation:
|
minus strand |
|
Proteins
for USP22 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBP22_HUMAN, Q9UPT9 (See
protein sequence)Recommended Name: Ubiquitin carboxyl-terminal hydrolase 22 Size: 525 amino acids; 59961 Da
Subunit: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2,GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex requiredfor histone deubiquitination. Interacts directly with ATXN7L3; leading to its recritment to the SAGA complex
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAH25317.1; Type=Frameshift; Positions=355; Sequence=BAA83015.1; Type=Erroneous initiation;
Secondary accessions: A0JNS3 Q2NLE2 Q6MZY4 Q8TBS8 Q96IW5Alternative splicing: 2 isoforms: Q9UPT9-1 Q9UPT9-2 (Ref.2 (AAI10500) sequence differs from that shown due to a frameshift in position 3)Explore the universe of human proteins at neXtProt for USP22: NX_Q9UPT9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPT9
4/19 DME Specific Peptides for USP22 (Q9UPT9) (see all 19)
USP22 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056091.1
ENSEMBL proteins: ENSP00000261497 ENSP00000440950 ENSP00000464398 ENSP00000464499 ENSP00000468457 ENSP00000468748
Human Recombinant Protein Products for USP22:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
USP22 for ontologies About GeneDecksing
USP22 Antibody Products:
Assay Products for USP22: |
Protein
Domains /
Families
for USP22 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP22 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UPT9ProtoNet protein and cluster: Q9UPT9 2 Blocks protein families: IPB001394 Ubiquitin thiolesterase IPB001607 Zn-finger in ubiquitin thiolesterase
UniProtKB/Swiss-Prot: UBP22_HUMAN, Q9UPT9Similarity: Belongs to the peptidase C19 family. UBP8 subfamilySimilarity: Contains 1 UBP-type zinc finger |
Function
for USP22 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UBP22_HUMAN, Q9UPT9Function: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specificgene promoters by activators such as MYC, where it is required for transcription. Required for nuclearreceptor-mediated transactivation and cell cycle progressionCatalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
USP22 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for USP22:
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Usp22):
USP22 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Usp22tm1Dfan for USP22
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: USP22 (NM_015276) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP22 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP22 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP22 |
|
Pathways & Interactions
for USP22 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP22
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/156 Interacting proteins for USP22 (Q9UPT92, 3 ENSP000002614974) via UniProtKB, MINT, STRING, and/or I2D (see all 156)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
USP22 for ontologies About GeneDecksing
|
Drugs & Compounds
for USP22 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for USP22
1 HMDB Compound for USP22 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Water | Dihydrogen oxide (see all 2) | 7732-18-5 | -- |
Search CenterWatch for drugs/clinical trials and news about USP22 / UBP22
|
Transcripts
for USP22 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for USP22 gene: NM_015276.1 Unigene Cluster for USP22: Ubiquitin specific peptidase 22 Hs.462492 [show with all ESTs]Unigene Representative Sequence: AB02898611 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000261497(uc002gym.4) ENST00000537526(uc002gyn.4 uc002gyl.4)
ENST00000455117 ENST00000579645 ENST00000463692 ENST00000478443 ENST00000582335
ENST00000577610 ENST00000578446 ENST00000476111 ENST00000584538
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: USP22 (NM_015276) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP22 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP22 |
Additional cDNA sequence: AB028986.1 AK025331.1 AK130677.1 AL049258.1 AL110213.1 BC007196.1 BC013364.2 BC025317.1 BC050994.1 BC084550.1 BC110499.1 BC126897.1 BC126898.1 BX640815.1 24/32 DOTS entries (see all 32): DT.100859449 DT.100661813 DT.40217429 DT.92459034 DT.100661806 DT.91694319 DT.92459044 DT.92459033 DT.97862469 DT.100661797 DT.121013189 DT.95275660 DT.100763760 DT.86844614 DT.97776493 DT.97777524 DT.100661807 DT.121013190 DT.121013197 DT.121013238 DT.121013385 DT.428942 DT.91654792 DT.91873243 24/891 AceView cDNA sequences (see all 891): BM992869 BQ226421 CF129237 BU734622 T09384 BG675938 BG680836 BQ222892 BU174127 AI570695 BQ672767 N73943 BI711250 BM451998 BQ642658 BM458984 AI127160 BU155590 BF993829 F09541 BE701537 CF528218 BM688372 AA349194
GeneLoc Exon Structure
|
Expression
for USP22 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP22 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTTTCCCT
About this image
See USP22 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP22
SOURCE GeneReport for Unigene cluster: Hs.462492
UniProtKB/Swiss-Prot: UBP22_HUMAN, Q9UPT9Tissue specificity: Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressedin lung and liver
SABiosciences Expression via Pathway-Focused PCR Array including USP22: | Epigenetic Chromatin Modification Enzymes in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP22
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP22 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP22 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP22 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP22 |
Orthologs
for USP22 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for USP22 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
USP221 |
ubiquitin specific peptidase 22 |
83.37(n)
96.18(a) |
|
416501 XM_414805.3 XP_414805.2 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.254812 |
Xenopus laevis transcribed sequence with strong similarity more |
78.94(n) |
|
BU914152.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
usp221 |
ubiquitin specific peptidase 22 |
80.02(n)
91.07(a) |
|
692275 NM_001045248.1 NP_001038713.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
not1 , 3 |
axon target recognition ubiquitin-specific
protease3
non-stop1 |
54(a)3
60.99(n)1
57.66(a)1 |
|
3 75D43
400301 NM_079416.31 NP_524140.21 |
worm
(Caenorhabditis elegans) |
Secernentea |
T22F3.26 |
Protein T22F3.2, isoform b |
16(a) |
possible ortholog |
V(3586637-3589004) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
UBP8(YMR223W)4
UBP81 |
Ubiquitin-specific protease that is a component of more4
Ubp8p1 |
45.51(n)1
37.56(a)1 |
|
13(716715-718130)4
8552631, 4 NP_013950.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
UBP226 |
ubiquitin carboxyl-terminal hydrolase 22 |
32(a) |
1 → many |
5(3410539-3412633) |
rice
(Oryza sativa) |
Liliopsida |
Os04g06473001 |
hypothetical protein |
50(n)
43.39(a) |
|
4337205 NM_001060605.2 NP_001054070.2 |
ENSEMBL Gene Tree for USP22 (if available)
TreeFam Gene Tree for USP22 (if available) |
Paralogs
for USP22 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for USP22 gene
- USP332 USP32 USP442 USP452 USP512 USP162 USP492 USP202
6 SIMAP similar genes for USP22 using alignment to 5 protein entries: UBP22_HUMAN (see all proteins):DKFZp434K1822 USP27X USP51 USP36 USP11 USP15
USP22 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for USP22
PGOHUM00000232645 PGOHUM00000233154 PGOHUM00000241752
|
Genomic Variants
for USP22 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for USP22 (20902906 - 20947073 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for USP22
2 CNVs: 8836 72832 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP22 |
|
Disorders
/ Diseases
for USP22 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP22 for disorders About GeneDecksing
OMIM gene information: 612116
OMIM disorders: --
2  diseases for USP22: About MalaCardscolorectal cancer breast cancer
Export disorders for USP22 gene to outside databases
|
Publications
for USP22 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP22 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with USP22) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. (PubMed id 18206972)1, 2 Zhao Y.... Devys D. (2008)
- The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. (PubMed id 18206973)1, 2 Zhang X.Y....McMahon S.B. (2008)
- USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A. (PubMed id 18469533)1, 2 Zhang X.Y....McMahon S.B. (2008)
- The expression patterns of deubiquitinating enzymes, USP22 and Usp22. (PubMed id 16378762)1, 2 Lee H.J....Baek K.H. (2006)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
- USP22 antagonizes p53 transcriptional activation by de ubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryo nic development. (PubMed id 22542455)1 Lin Z....Fang D. (2012)
- USP22 is useful as a novel molecular marker for predic ting disease progression and patient prognosis of oral squamous cell carcinoma. (PubMed id 22880026)1 Piao S....Zhang B. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- USP22 nuclear expression is significantly associated w ith progression and unfavorable clinical outcome in human esophageal squamous ce ll carcinoma. (PubMed id 22447106)1 Li J....Li Y. (2012)
|
External Searches for USP22 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing USP22 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP22 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing USP22 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for USP22 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP22 gene:
Search GeneIP for patents involving USP22
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for USP22 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for USP22 | | OriGene shRNA RFP for USP22 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP22 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP22 | | | OriGene Protein Over-expression Lysate for USP22 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for USP22 | | OriGene 3'-UTR Clone for USP22 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP22 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for USP22 | | OriGene Custom Protein Services for USP22 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP22 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP22 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP22 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP22 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP22 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP22 |
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| | | | Search Tocris compounds for USP22 |
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 | | | USP22 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP22 |
|  |  |  |  | | | | ThermoFisher Antibodies for USP22 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP22 |
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