USP18 Gene
protein-coding GIFtS: 59
GCID: GC22P018632
|
|
ubiquitin specific peptidase 18(Previous name: ubiquitin specific protease 18 )
| |
Aliases
for USP18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 181 2 | | ISG15-Specific-Processing Protease2 3 | | ISG432 3 5 | | UBP432 5 | | Ubiquitin Specific Protease 181 2 | | Ubl Carboxyl-Terminal Hydrolase 182 | | Ubl Thioesterase 182 3 | | Ubl Thiolesterase 182 | | 43 KDa ISG15-Specific Protease2 3 | | EC 3.4.19.-3 | | HUBP431 | | EC 3.1.2.158 |
Export aliases for USP18 gene to outside databasesPrevious GC identifers: GC22P015573 GC22P017007 GC22P002445 |
Summaries
for USP18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for USP18:
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleaveubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to thenucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene inmice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a majorISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of thisprotein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. (provided byRefSeq, Sep 2011)
UniProtKB/Swiss-Prot: UBP18_HUMAN, Q9UMW8Function: Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds.Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms
Gene Wiki entry for USP18
|
Genomic Views
for USP18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011519.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the USP18 gene promoter:
STAT1 HTF Pax-2 STAT1beta Pax-2a STAT1alpha Pax-2b POU2F1 HOXA5 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for USP18
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP18 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.2USP18 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P018632: view genomic region
(about GC identifiers)
Start:
|
18,632,666 bp from pter |
End:
|
18,660,164 bp from pter |
Size:
|
27,499 bases |
Orientation:
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plus strand |
|
Proteins
for USP18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBP18_HUMAN, Q9UMW8 (See
protein sequence)Recommended Name: Ubl carboxyl-terminal hydrolase 18 Size: 372 amino acids; 43011 Da
Secondary accessions: Q6IAD9 Q9NY71Explore the universe of human proteins at neXtProt for USP18: NX_Q9UMW8
3 DME Specific Peptides for USP18 (Q9UMW8)
USP18 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_059110.2
ENSEMBL proteins: ENSP00000215794 Reactome Protein details: Q9UMW8
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
USP18 for ontologies About GeneDecksing
USP18 Antibody Products:
Assay Products for USP18: |
Protein
Domains /
Families
for USP18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP18 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UMW8ProtoNet protein and cluster: Q9UMW8 1 Blocks protein family: IPB001394 Ubiquitin thiolesterase
UniProtKB/Swiss-Prot: UBP18_HUMAN, Q9UMW8Similarity: Belongs to the peptidase C19 family |
Function
for USP18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBP18_HUMAN, Q9UMW8Function: Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds.Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organismsCatalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Genatlas biochemistry entry for USP18:ubiquitin specific protease 18,deubiquitin enzyme family
Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.-1
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for USP18 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP18 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP18 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004221 | ubiquitin thiolesterase activity |
IEA | -- | | GO:0004843 | ubiquitin-specific protease activity |
TAS | 10777664 |
USP18 for ontologies About GeneDecksing
Animal Models:
8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Usp18):
USP18 for phenotypes About GeneDecksing
|
Pathways & Interactions
for USP18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of IFNA signaling | | | 2 | Cytokine Signaling in Immune system | | | 3 | Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus | | | 4 | Protein Stability | | | 5 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for USP18
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP18
1 
Cell Signaling Technology (CST) Pathway for USP18
1  GeneGo (Thomson Reuters) Pathway for USP18
5/8 
Reactome Pathways for USP18 (see all 8)
USP18 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP18
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/10 Interacting proteins for USP18 (Q9UMW82, 3 ENSP000002157944) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process |
IEA | -- | | GO:0019221 | cytokine-mediated signaling pathway |
TAS | -- | | GO:0060337 | type I interferon-mediated signaling pathway |
TAS | -- | | GO:0060338 | regulation of type I interferon-mediated signaling pathway |
TAS | -- |
USP18 for ontologies About GeneDecksing
|
Drugs & Compounds
for USP18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for USP18
Search CenterWatch for drugs/clinical trials and news about USP18 / UBP18
|
Transcripts
for USP18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for USP18 gene: NM_017414.3 Unigene Cluster for USP18: Ubiquitin specific peptidase 18 Hs.38260 [show with all ESTs]Unigene Representative Sequence: NM_0174141 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000215794(uc002zny.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP18 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: USP18 (NM_017414) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP18 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP18 |
Additional cDNA sequence: AF176642.2 AJ243526.1 AJ583822.1 AJ586979.1 AK303463.1 AK313385.1 AL136690.1 BC014896.1 BT006835.1 CR457216.1 CT841507.1 13 DOTS entries: DT.100699062 DT.100775966 DT.120667954 DT.451675 DT.120642020 DT.120646499 DT.120668581 DT.100641117 DT.91725649 DT.92422619 DT.102825674 DT.87046339 DT.95287161 24/63 AceView cDNA sequences (see all 63): CR604420 BQ213074 BC014896 BQ018510 BU616063 AI222587 CD364378 AI055870 AA976038 NM_017414 AW136867 AA136383 AL136690 AI352180 BT006835 BF089771 BX280356 AW172474 BU584005 CR457216 BX344048 BM807263 AF176642 BI752849
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for USP18 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for USP18
|
Expression
for USP18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See USP18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP18
SOURCE GeneReport for Unigene cluster: Hs.38260
SABiosciences Custom PCR Arrays for USP18
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP18
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP18 |
Orthologs
for USP18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for USP18 gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
USP181 |
ubiquitin specific peptidase 18 |
60.87(n)
53.62(a) |
|
418167 XM_416398.2 XP_416398.2 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
55(a) |
1 → many |
5(14365848-14374457) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1003345351 |
ubl carboxyl-terminal hydrolase 18-like |
46.43(n)
33.87(a) |
|
100334535 XM_002661352.1 XP_002661398.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
usp-486 |
-- |
5(a) |
possible ortholog |
I(9506545-9511177) |
ENSEMBL Gene Tree for USP18 (if available)
TreeFam Gene Tree for USP18 (if available) |
Paralogs
for USP18 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for USP18 gene
- USP242 USP412 USP482 USP402 USP72 USP472 USP9Y2 USP342
- USP9X2
2 SIMAP similar genes for USP18 using alignment to 1 protein entry: UBP18_HUMAN:USP41 Em
USP18 for paralogs About GeneDecksing
|
Genomic Variants
for USP18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for USP18 (18632666 - 18660164 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for USP18
14 CNVs: 3237 73705 79445 31070 90878 2258 34485 34618 8900 4116 9330 0814 73706 7331 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP18 |
|
Disorders
/ Diseases
for USP18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP18 for disorders About GeneDecksing
OMIM gene information: 607057
OMIM disorders: --
9  diseases for USP18: About MalaCardslymphocytic choriomeningitis digeorge syndrome burkitt's lymphoma hepatitis c
hepatitis b hepatitis lung cancer melanoma
malaria
Export disorders for USP18 gene to outside databases
|
Publications
for USP18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP18 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with USP18) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18). (PubMed id 10777664)1, 2, 9 Schwer H.... Hetherington C.J. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- UBP43 (USP18) specifically removes ISG15 from conjugated proteins. (PubMed id 11788588)1, 2 Malakhov M.P.... Zhang D.-E. (2002)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response. (PubMed id 10722734)1, 9 Li X.L....Hassel B.A. (2000)
- A microarray of ubiquitylated proteins for profiling d eubiquitylase activity reveals the critical roles of both chain and substrate. (PubMed id 22626734)1 Loch C.M. and Strickler J.E. (2012)
- Interferon-g-stimulated genes, but not USP18, are expressed in livers of patients with acute hepatitis C. (PubMed id 22677194)1 Dill M.T....Heim M.H. (2012)
- Evidence for the ubiquitin protease UBP43 as an antine oplastic target. (PubMed id 22752428)1 Guo Y....Dmitrovsky E. (2012)
- USP18 establishes the transcriptional and anti-prolife rative interferon a/b differential. (PubMed id 22731491)1 Francois-Newton V....Pellegrini S. (2012)
|
External Searches for USP18 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing USP18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP18 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USP18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for USP18 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP18 gene:
Search GeneIP for patents involving USP18
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for USP18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP18 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP18 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP18 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP18 |
| |
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| | | | Search Tocris compounds for USP18 |
| |  |  |  |  | | | | |
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 | | | USP18 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP18 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP18 |
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