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Aliases for USP17L8 Gene

Aliases for USP17L8 Gene

  • Ubiquitin Specific Peptidase 17-Like Family Member 8 2 3 5
  • Ubiquitin Specific Peptidase 17-Like 8 2 3
  • EC 63
  • USP17L10 3

External Ids for USP17L8 Gene

Previous GeneCards Identifiers for USP17L8 Gene

  • GC08M007870
  • GC08M007874
  • GC08M007831

Summaries for USP17L8 Gene

GeneCards Summary for USP17L8 Gene

USP17L8 (Ubiquitin Specific Peptidase 17-Like Family Member 8) is a Protein Coding gene. GO annotations related to this gene include thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP36.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for USP17L8 Gene

Genomics for USP17L8 Gene

Regulatory Elements for USP17L8 Gene

Enhancers for USP17L8 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around USP17L8 on UCSC Golden Path with GeneCards custom track

Genomic Location for USP17L8 Gene

7,971,661 bp from pter
7,977,985 bp from pter
6,325 bases
Minus strand

Genomic View for USP17L8 Gene

Genes around USP17L8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
USP17L8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for USP17L8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for USP17L8 Gene

Proteins for USP17L8 Gene

  • Protein details for USP17L8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8
    Protein Accession:

    Protein attributes for USP17L8 Gene

    530 amino acids
    Molecular mass:
    59635 Da
    Quaternary structure:
    No Data Available

neXtProt entry for USP17L8 Gene

Proteomics data for USP17L8 Gene at MOPED

Post-translational modifications for USP17L8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for USP17L8 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for USP17L8 Gene

Protein Domains for USP17L8 Gene


Suggested Antigen Peptide Sequences for USP17L8 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 USP domain.
  • Belongs to the peptidase C19 family. USP17 subfamily.
  • Contains 1 USP domain.
  • Belongs to the peptidase C19 family. USP17 subfamily.
genes like me logo Genes that share domains with USP17L8: view

No data available for Gene Families for USP17L8 Gene

Function for USP17L8 Gene

Enzyme Numbers (IUBMB) for USP17L8 Gene

Phenotypes for USP17L8 Gene

genes like me logo Genes that share phenotypes with USP17L8: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for USP17L8 Gene

Localization for USP17L8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USP17L8 Gene

Nucleus. Endoplasmic reticulum.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for USP17L8 Gene

Pathways & Interactions for USP17L8 Gene

SuperPathways for USP17L8 Gene

No Data Available

Interacting Proteins for USP17L8 Gene

Gene Ontology (GO) - Biological Process for USP17L8 Gene


No data available for Pathways by source and SIGNOR curated interactions for USP17L8 Gene

Drugs & Compounds for USP17L8 Gene

No Compound Related Data Available

Transcripts for USP17L8 Gene

mRNA/cDNA for USP17L8 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for USP17L8 Gene

No ASD Table

Relevant External Links for USP17L8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for USP17L8 Gene

mRNA expression in normal human tissues for USP17L8 Gene

SOURCE GeneReport for Unigene cluster for USP17L8 Gene Hs.741135

genes like me logo Genes that share expression patterns with USP17L8: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for USP17L8 Gene

Orthologs for USP17L8 Gene

Evolution for USP17L8 Gene

Gene Tree for USP17L8 (if available)
Gene Tree for USP17L8 (if available)

No data available for Orthologs for USP17L8 Gene

Paralogs for USP17L8 Gene

genes like me logo Genes that share paralogs with USP17L8: view

Variants for USP17L8 Gene

Relevant External Links for USP17L8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for USP17L8 Gene

Disorders for USP17L8 Gene

Relevant External Links for USP17L8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for USP17L8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for USP17L8 Gene

Publications for USP17L8 Gene

  1. Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. (PMID: 17109758) Shin J.-M. … Baek K.-H. (BMC Genomics 2006) 2 3 4 67
  2. The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence. (PMID: 15780755) Burrows J.F. … Johnston J.A. (Genomics 2005) 2 3
  3. Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. (PMID: 21239494) Ramakrishna S. … Baek K.H. (J. Biol. Chem. 2011) 3
  4. The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility. (PMID: 21448158) de la Vega M. … Johnston J.A. (Nat. Commun. 2011) 3
  5. Cdc25A and Dub3 in a high-stakes balancing act. (PMID: 20228807) Hayes S.D. … Harper J.W. (Nat. Cell Biol. 2010) 3

Products for USP17L8 Gene

Sources for USP17L8 Gene