Free for academic non-profit institutions. Other users need a Commercial license

Aliases for USP17L8 Gene

Aliases for USP17L8 Gene

  • Ubiquitin Specific Peptidase 17-Like Family Member 8 2 3
  • Ubiquitin Specific Peptidase 17-Like 8 2 3
  • Inactive Ubiquitin Carboxyl-Terminal Hydrolase 17-Like Protein 8 3
  • EC 3.1.2.15 63
  • USP17L10 3

External Ids for USP17L8 Gene

Summaries for USP17L8 Gene

GeneCards Summary for USP17L8 Gene

USP17L8 (Ubiquitin Specific Peptidase 17-Like Family Member 8) is a Protein Coding gene. GO annotations related to this gene include ubiquitin thiolesterase activity. An important paralog of this gene is USP17L4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for USP17L8 Gene

Genomics for USP17L8 Gene

Genomic Location for USP17L8 Gene

Start:
7,971,661 bp from pter
End:
7,977,985 bp from pter
Size:
6,325 bases
Orientation:
Minus strand

Genomic View for USP17L8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for USP17L8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for USP17L8 Gene

Regulatory Elements for USP17L8 Gene

Proteins for USP17L8 Gene

  • Protein details for USP17L8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7I0-U17L8_HUMAN
    Recommended name:
    Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8
    Protein Accession:
    P0C7I0
    Secondary Accessions:

    Protein attributes for USP17L8 Gene

    Size:
    530 amino acids
    Molecular mass:
    59635 Da
    Quaternary structure:
    No Data Available

neXtProt entry for USP17L8 Gene

Proteomics data for USP17L8 Gene at MOPED

Post-translational modifications for USP17L8 Gene

No Post-translational modifications

Other Protein References for USP17L8 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains for USP17L8 Gene

Protein Domains for USP17L8 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for USP17L8 Gene

Graphical View of Domain Structure for InterPro Entry

P0C7I0

UniProtKB/Swiss-Prot:

U17L8_HUMAN
Domain:
  • Contains 1 USP domain.:
    • P0C7I0
Family:
  • Belongs to the peptidase C19 family. USP17 subfamily.:
    • P0C7I0
genes like me logo Genes that share domains with USP17L8: view

No data available for Gene Families for USP17L8 Gene

Function for USP17L8 Gene

Enzyme Numbers (IUBMB) for USP17L8 Gene

Gene Ontology (GO) - Molecular Function for USP17L8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0036459 ubiquitinyl hydrolase activity IEA --
genes like me logo Genes that share ontologies with USP17L8: view

No data available for Molecular function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for USP17L8 Gene

Localization for USP17L8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USP17L8 Gene

Nucleus. Endoplasmic reticulum.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for USP17L8 Gene COMPARTMENTS Subcellular localization image for USP17L8 gene
Compartment Confidence
cytosol 2
endoplasmic reticulum 2
nucleus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for USP17L8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005783 endoplasmic reticulum IEA --
genes like me logo Genes that share ontologies with USP17L8: view

Pathways for USP17L8 Gene

SuperPathways for USP17L8 Gene

No Data Available

Interacting Proteins for USP17L8 Gene

Gene Ontology (GO) - Biological Process for USP17L8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
genes like me logo Genes that share ontologies with USP17L8: view

No data available for Pathways by source for USP17L8 Gene

Transcripts for USP17L8 Gene

mRNA/cDNA for USP17L8 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for USP17L8 Gene

No ASD Table

Relevant External Links for USP17L8 Gene

GeneLoc Exon Structure for
USP17L8
ECgene alternative splicing isoforms for
USP17L8

Expression for USP17L8 Gene

mRNA expression in normal human tissues for USP17L8 Gene

SOURCE GeneReport for Unigene cluster for USP17L8 Gene Hs.741135

genes like me logo Genes that share expressions with USP17L8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for USP17L8 Gene

Orthologs for USP17L8 Gene

Evolution for USP17L8 Gene

ENSEMBL:
Gene Tree for USP17L8 (if available)
TreeFam:
Gene Tree for USP17L8 (if available)

No data available for Orthologs for USP17L8 Gene

Paralogs for USP17L8 Gene

Paralogs for USP17L8 Gene

genes like me logo Genes that share paralogs with USP17L8: view

Variants for USP17L8 Gene

Relevant External Links for USP17L8 Gene

HapMap Linkage Disequilibrium report
USP17L8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for USP17L8 Gene

Disorders for USP17L8 Gene

No disorders were found for USP17L8 Gene.

No data available for UniProtKB/Swiss-Prot for USP17L8 Gene

Publications for USP17L8 Gene

  1. Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. (PMID: 17109758) Shin J.-M. … Baek K.-H. (BMC Genomics 2006) 2 3 4
  2. The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence. (PMID: 15780755) Burrows J.F. … Johnston J.A. (Genomics 2005) 2 3 4
  3. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 3 4
  4. Cytokine-regulated protein degradation by the ubiquitination system. (PMID: 16611142) Baek K.H. (Curr. Protein Pept. Sci. 2006) 3
  5. Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation. (PMID: 9806828) Gondo Y. … Ikeda J.E. (Genomics 1998) 3

Products for USP17L8 Gene

Sources for USP17L8 Gene

Back to Top

Content