USP12 Gene
protein-coding GIFtS: 54
GCID: GC13M027640
|
|
ubiquitin specific peptidase 12(Previous names: ubiquitin specific protease 12 like 1, ubiquitin specific...) (Previous symbol: USP12L1)
| |
Aliases for USP12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 121 2 | | Ubiquitin-Specific-Processing Protease 122 3 | | USP12L11 2 3 | | Ubiquitin Specific Protease 121 | | UBH12 3 5 | | Ubiquitin Carboxyl-Terminal Hydrolase 122 | | Ubiquitin Specific Protease 12 Like 11 2 | | Ubiquitin Thiolesterase 122 | | Deubiquitinating Enzyme 122 3 | | EC 3.4.19.123 | | Ubiquitin Thioesterase 122 3 | | EC 3.1.2.158 | | Ubiquitin-Hydrolyzing Enzyme 12 3 | | |
Export aliases for USP12 gene to outside databasesPrevious GC identifers: GC05U990084 GC13M026570 GC13M025440 GC13M025438 GC13M026540 GC13M008462 |
Summaries for USP12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: UBP12_HUMAN, O75317Function: Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction withWDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2
|
Genomic Views for USP12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the USP12 gene promoter: Bach1 FOXF2 Nkx2-2 FOXD3 IRF-2 POU2F1 POU2F1a FOXJ2 (long isoform) FOXJ2 Ik-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for USP12
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP12 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q12.13 Ensembl cytogenetic band: 13q12.13 HGNC cytogenetic band: 13q12.13USP12 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M027640: view genomic region
(about GC identifiers)
Start:
|
27,640,287 bp from pter |
End:
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27,746,033 bp from pter |
Size:
|
105,747 bases |
Orientation:
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minus strand |
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Proteins for USP12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: UBP12_HUMAN, O75317 (See
protein sequence)Recommended Name: Ubiquitin carboxyl-terminal hydrolase 12 Size: 370 amino acids; 42858 Da
Subunit: Interacts with WDR48
Sequence caution: Sequence=AAC23551.1; Type=Erroneous initiation;
Secondary accessions: A8K0X0 Q5VZV3 Q8TC49Explore the universe of human proteins at neXtProt for USP12: NX_O75317
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75317 4/16 DME Specific Peptides for USP12 (O75317) (see all 16)
USP12 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins: NP_872294.2 ENSEMBL proteins: ENSP00000282344 Human Recombinant Protein Products for USP12:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
USP12 for ontologies About GeneDecksing
USP12 Antibody Products: Assay Products for USP12: |
Protein
Domains / Families for USP12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP12 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O75317ProtoNet protein and cluster: O75317 1 Blocks protein family: IPB001394 Ubiquitin thiolesterase
UniProtKB/Swiss-Prot: UBP12_HUMAN, O75317Similarity: Belongs to the peptidase C19 family. USP12/USP46 subfamily |
Function for USP12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: UBP12_HUMAN, O75317Function: Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction withWDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Genatlas biochemistry entry for USP12:ubiquitin specific protease 12,mainly expressed in retina,olfactory epithelium,peripheral neuronal ganglia and distinctareas of the gut,involved in deubiquitina,deubiquitin enzyme family Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
USP12 for ontologies About GeneDecksing
Phenotypes: 2 GenomeRNAi human phenotypes for USP12: Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for USP12 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP12  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP12 |
|
Pathways & Interactions for USP12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ubiquitin-Proteasome Dependent Proteolysis | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP12
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USP12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
 5/25 Interacting proteins for USP12 (O753173 ENSP000002823444) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006464 | cellular protein modification process |
NAS | -- | | GO:0006511 | ubiquitin-dependent protein catabolic process |
IEA | -- | | GO:0016579 | protein deubiquitination |
IDA | 19075014 |
USP12 for ontologies About GeneDecksing
|
Drugs & Compounds for USP12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for USP12 Search CenterWatch for drugs/clinical trials and news about USP12 / UBP12 
|
Transcripts for USP12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for USP12 gene: NM_182488.3 Unigene Cluster for USP12: Ubiquitin specific peptidase 12 Hs.42400 [show with all ESTs]Unigene Representative Sequence: NM_1824881 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000282344(uc001uqy.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for USP12 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP12  |
Additional cDNA sequence: AF022789.1 AK289685.1 AL049221.1 BC026072.1 12 DOTS entries: DT.75187513 DT.409156 DT.101967297 DT.75127843 DT.97770033 DT.100660226 DT.120652128 DT.91913091 DT.95231244 DT.91740469 DT.99935569 DT.99995190 24/188 AceView cDNA sequences (see all 188): AA412513 BX099332 BU676227 AA459676 AA459786 BM930847 AA418174 BM803688 CB217149 CA309356 F03956 BM021355 AF022793 AA405037 BF002096 AA832295 AI346242 AI478322 BE504549 W38373 AA459664 AW501808 CD516704 AA453343 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for USP12 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | |
| SP1: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for USP12
|
Expression for USP12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP12 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TCCTGGCTCT
 About this image See USP12 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for USP12
SOURCE GeneReport for Unigene cluster: Hs.42400 SABiosciences Custom PCR Arrays for USP12
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP12 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP12 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP12 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP12 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP12 |
Orthologs for USP12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for USP12 gene from 8/31 species (see all 31) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
USP121 |
ubiquitin specific peptidase 12 |
89.17(n) 99.15(a) |
  |
428078 XM_425636.3 XP_425636.3 |
lizard (Anolis carolinensis) |
Reptilia |
USP126 |
-- |
95(a) |
1 ↔ 1 |
GL343306.1(1003521-1014270) |
zebrafish (Danio rerio) |
Actinopterygii |
usp12a1 |
ubiquitin specific peptidase 12a |
76.94(n) 93.51(a) |
  |
565736 NM_001083556.1 NP_001077025.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG70236 |
-- |
62(a) |
1 → many |
3R(18576614-18602096) |
worm (Caenorhabditis elegans) |
Secernentea |
usp-466 |
Probable ubiquitin carboxyl-terminal hydrolase 46 |
57(a) |
1 → many |
III(9776446-9778763) |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
UBP91 |
Ubp9p |
53.23(n) 43.87(a) |
  |
856835 NP_011024.1 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
UBP31 |
ubiquitin carboxyl-terminal hydrolase 3 |
61.05(n) 61.71(a) |
  |
830150 NM_120154.4 NP_568074.1 |
rice (Oryza sativa) |
Liliopsida |
AK069100.12 |
-- |
71.44(n) |
  |
AK069100.1 |
ENSEMBL Gene Tree for USP12 (if available) TreeFam Gene Tree for USP12 (if available)  |
Paralogs for USP12 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for USP12 gene
- USP352 USP382 USP462 USP12
2 SIMAP similar genes for USP12 using alignment to 1 protein entry: UBP12_HUMAN:USP46 USP3
USP12 for paralogs About GeneDecksing
5/8 Pseudogenes.org Pseudogenes for USP12 (see all 8) PGOHUM00000240379 PGOHUM00000235832 PGOHUM00000236042 PGOHUM00000236049 PGOHUM00000236057
|
Genomic Variants for USP12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 13 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for USP12 (27640287 - 27746033 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for USP12: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP12 |
|
Disorders
/ Diseases for USP12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP12 for disorders About GeneDecksing
OMIM gene information: 603091
OMIM disorders: --
3 diseases for USP12: About MalaCardsulcerative colitis schizophrenia neuronitis 1 disease from the University of Copenhagen DISEASES database for USP12:Fanconi's anemia Export disorders for USP12 gene to outside databases
|
Publications for USP12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP12 gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with USP12) | |  | Utopia: connect your pdf to the dynamic world of online information |
- An evolutionarily conserved gene on human chromosome 5q33-q34, UBH1, encodes a novel deubiquitinating enzyme. (PubMed id 9615226)1, 2, 9 Hansen-Hagge T.E....Bartram C.R. (1998)
- UAF1 is a subunit of multiple deubiquitinating enzyme complexes. (PubMed id 19075014)1, 2 Cohn M.A.... D'Andrea A.D. (2009)
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- The ubiquitin-specific protease 12 (USP12) is a negati ve regulator of notch signaling acting on notch receptor trafficking toward degr adation. (PubMed id 22778262)1 Moretti J....Brou C. (2012)
- Genomewide association analysis of symptoms of alcoho l dependence in the molecular genetics of schizophrenia (MGS2) control sample. (PubMed id 21314694)1 Kendler K.S....Gejman P.V. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Regulation of histone H2A and H2B deubiquitination an d Xenopus development by USP12 and USP46. (PubMed id 21183687)1 Joo H.Y....Wang H. (2011)
- WDR20 regulates activity of the USP12 x UAF1 deubiqui tinating enzyme complex. (PubMed id 20147737)1 Kee Y....D'Andrea A.D. (2010)
|
External Searches for USP12 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing USP12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USP12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for USP12 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP12 gene: Search GeneIP for patents involving USP12
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for USP12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for USP12 | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP12 | | OriGene Protein Over-expression Lysate for USP12 | | Browse OriGene Fluorogenic Cell Assay Kits | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for USP12 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP12 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for USP12 | | OriGene Custom Protein Services for USP12 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP12 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP12 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP12 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP12 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP12 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP12 |
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| | | Search Tocris compounds for USP12 |
| |  |  |  |  | | | | |
 |
 |
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 | | USP12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP12 |
|  |  |  |  | | | ThermoFisher Antibody for USP12 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP12 |
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