USP11 Gene
protein-coding GIFtS: 61
GCID: GC0XP047093
|
|
ubiquitin specific peptidase 11(Previous name: ubiquitin specific protease 11 )
| |
Aliases
for USP11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Specific Peptidase 111 2 | | Ubiquitin Carboxyl-Terminal Hydrolase 112 | | UHX11 2 3 5 | | Ubiquitin Carboxyl-Terminal Hydrolase, X-Linked2 | | Deubiquitinating Enzyme 112 3 | | Ubiquitin Thiolesterase 112 | | Ubiquitin Thioesterase 112 3 | | Ubiquitin-Specific Processing Protease 112 | | Ubiquitin-Specific-Processing Protease 112 3 | | EC 3.4.19.123 | | Ubiquitin Specific Protease 111 | | EC 3.1.2.158 |
Export aliases for USP11 gene to outside databasesPrevious GC identifers: GC0XP045895 GC0XP045352 GC0XP045918 GC0XP046138 GC0XP046848 GC0XP046977 GC0XP044802 |
Summaries
for USP11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for USP11:
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptionalactivation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes anddeubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases thatspecifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinatingenzyme which lies in a gene cluster on chromosome Xp11.23 (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: UBP11_HUMAN, P51784Function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits thedegradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-Bactivation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks
Gene Wiki entry for USP11
|
Genomic Views
for USP11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_079573.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the USP11 gene promoter:
E2F-4 E2F-3a E2F-5 p53 E2F-2 GATA-2 E2F E2F-1 POU2F1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for USP11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23USP11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP047093: view genomic region
(about GC identifiers)
Start:
|
47,092,089 bp from pter |
End:
|
47,107,727 bp from pter |
Size:
|
15,639 bases |
Orientation:
|
plus strand |
|
Proteins
for USP11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBP11_HUMAN, P51784 (See
protein sequence)Recommended Name: Ubiquitin carboxyl-terminal hydrolase 11 Size: 963 amino acids; 109817 Da
Subunit: Interacts with RANBP9/RANBPM. Interacts with BRCA2, CHUK/IKKA and NFKBIA. Interacts with papilloma virusprotein 16E7
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear. Associates with chromatin
Caution: It is uncertain whether Met-1 or Met-44 is the initiator
Sequence caution: Sequence=AAC50450.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAC50450.1; Type=Frameshift; Positions=65, 117, 134, 146; Sequence=BAC20463.1; Type=Erroneous initiation;Sequence=CAD20056.1; Type=Erroneous gene model prediction;
Secondary accessions: B2RTX1 Q8IUG6 Q9BWE1Explore the universe of human proteins at neXtProt for USP11: NX_P51784
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P51784
4/11 DME Specific Peptides for USP11 (P51784) (see all 11)
USP11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004642.2
ENSEMBL proteins: ENSP00000366311 ENSP00000366282 ENSP00000366279 ENSP00000218348 Reactome Protein details: P51784
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
USP11 for ontologies About GeneDecksing
USP11 Antibody Products:
Assay Products for USP11: |
Protein
Domains /
Families
for USP11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USP11 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P51784ProtoNet protein and cluster: P51784 3 Blocks protein families: IPB001394 Ubiquitin thiolesterase IPB006615 Ubiquitin-specific protease DUSP IPB010460 Ubiquitin carboxyl-terminal hydrolase
UniProtKB/Swiss-Prot: UBP11_HUMAN, P51784Similarity: Belongs to the peptidase C19 familySimilarity: Contains 1 DUSP domain |
Function
for USP11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBP11_HUMAN, P51784Function: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits thedegradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-Bactivation. Plays a role in the regulation of DNA repair after double-stranded DNA breaksCatalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) Genatlas biochemistry entry for USP11:ubiquitin specific protease 11,highly expressed in the retina,deubiquitin enzyme family
Enzyme Numbers (IUBMB): EC 3.1.2.152 EC 3.4.19.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP11 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP11
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: USP11 (NM_004651) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP11 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
USP11 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for USP11:
|
Pathways & Interactions
for USP11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chaperonin-mediated protein folding | | | 2 | Ubiquitin-Proteasome Dependent Proteolysis | | | 3 | TNF-alpha/NF-kB Signaling Pathway | | | 4 | Asparagine N-linked glycosylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for USP11
1  BioSystems Pathway for USP11
4 
Reactome Pathways for USP11
USP11 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for USP11
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/148 Interacting proteins for USP11 (P517841, 2, 3 ENSP000002183484) via UniProtKB, MINT, STRING, and/or I2D (see all 148)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process |
IEA | -- | | GO:0016579 | protein deubiquitination |
IDA | 15314155 |
USP11 for ontologies About GeneDecksing
|
Drugs & Compounds
for USP11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for USP11
1 HMDB Compound for USP11 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Water | Dihydrogen oxide (see all 2) | 7732-18-5 | -- |
Search CenterWatch for drugs/clinical trials and news about USP11 / UBP11
|
Transcripts
for USP11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for USP11 gene: NM_004651.3 Unigene Cluster for USP11: Ubiquitin specific peptidase 11 Hs.171501 [show with all ESTs]Unigene Representative Sequence: BC14084912 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377107(uc004dhp.3 uc004dhq.3) ENST00000478596 ENST00000469080
ENST00000377080 ENST00000377078 ENST00000489111 ENST00000489030 ENST00000480104
ENST00000488848 ENST00000497179 ENST00000467378 ENST00000218348
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP11 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP11
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: USP11 (NM_004651) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USP11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP11 |
Additional cDNA sequence: AB073597.1 AK098394.1 AK294635.1 BC000350.2 BC063668.1 BC140849.1 U44839.1 24/50 DOTS entries (see all 50): DT.100886395 DT.40240774 DT.121286822 DT.121286751 DT.100842634 DT.91774475 DT.100886387 DT.100886384 DT.91774493 DT.100886386 DT.95175404 DT.100886385 DT.99965606 DT.97855317 DT.100886391 DT.97855318 DT.100720012 DT.121286744 DT.95175436 DT.100886392 DT.100038861 DT.121286761 DT.121286759 DT.121286720 24/815 AceView cDNA sequences (see all 815): AI369776 BF530148 F04842 AI984369 BC063668 AI903798 BE890067 CB155819 BM827845 BQ891743 BE859085 BU728398 CD619083 BQ935545 BG392606 CR606453 CA396064 AL079755 BU732167 BE888448 BE740495 AA446913 AA378795 BU850211
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for USP11 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14c | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for USP11
|
Expression
for USP11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| USP11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGTTAATT
About this image
See USP11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for USP11
SOURCE GeneReport for Unigene cluster: Hs.171501
SABiosciences Expression via Pathway-Focused PCR Array including USP11: | Polycomb & Trithorax Complexes in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USP11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP11 |
Orthologs
for USP11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for USP11 gene from 5/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
USP116 |
-- |
65(a) |
1 ↔ 1 |
2(68552689-68586557) |
zebrafish
(Danio rerio) |
Actinopterygii |
usp111 |
ubiquitin specific peptidase 11 |
58.58(n)
54.71(a) |
|
568334 XM_002663073.2 XP_002663119.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
H34C03.23 |
ubiquitin carboxy-terminal hydrolase |
54(a)
(best of 2) |
|
IV(6757531-6761964) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
UBP116UBP106(see all 5) |
ubiquitin carboxyl-terminal hydrolase 9(see all 5) |
32(a)32(a)(see all 5) |
many ↔ manymany ↔ many(see all 5) |
1(11902629-11906900) 4(6538541-6543448) |
rice
(Oryza sativa) |
Liliopsida |
Os.459462 |
Oryza sativa (japonica cultivar-group) OJ1714_H10.17 more |
69.62(n) |
|
NM_186392.1 |
ENSEMBL Gene Tree for USP11 (if available)
TreeFam Gene Tree for USP11 (if available) |
Paralogs
for USP11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for USP11 gene
- USP152 USP312 USP322 USP432 USP192 USP42 USP62
15 SIMAP similar genes for USP11 using alignment to 6 protein entries: UBP11_HUMAN (see all proteins):USP8 USP4 USP15 USP2 USP32 USP33
USP22 USP43 USP31 USP19 DKFZp761E10121 USP50
USP27X USP3 USP6
USP11 for paralogs About GeneDecksing
|
Genomic Variants
for USP11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for USP11 (47092089 - 47107727 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for USP11: --
Locus Specific Mutation Databases (LSDB): USP11
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP11 |
|
Disorders
/ Diseases
for USP11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USP11 for disorders About GeneDecksing
OMIM gene information: 300050
OMIM disorders: --
6  diseases for USP11: About MalaCardscongenital stationary night blindness night blindness retinal disease retinitis
blindness malaria
Export disorders for USP11 gene to outside databases
|
Publications
for USP11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USP11 gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with USP11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM. (PubMed id 12084015)1, 2, 9 Ideguchi H.... Ishigatsubo Y. (2002)
- USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha. (PubMed id 19874889)1, 2, 9 Sun W....Yang J. (2010)
- USP11 stabilizes HPV-16E7 and further modulates the E7 biological activity. (PubMed id 18408009)1, 2 Lin C.H....Yu W.C. (2008)
- The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha). (PubMed id 17897950)1, 2 Yamaguchi T....Yoshida K. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. (PubMed id 15314155)1, 2 Schoenfeld A.R....Aaronson S.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (2003)
- A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders. (PubMed id 8845848)1, 2 Swanson D.A.... Valle D. (1996)
- UHX1 and PCTK1: precise characterisation and localisation within a gene-rich region in Xp11.23 and evaluation as candidate genes for retinal diseases mapped to Xp21.1-p11.2. (PubMed id 9801870)1, 9 Brandau O....Meindl A. (1998)
|
External Searches for USP11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing USP11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USP11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USP11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for USP11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USP11 gene:
Search GeneIP for patents involving USP11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for USP11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for USP11 | | OriGene shRNA RFP for USP11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USP11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USP11 | | | OriGene Protein Over-expression Lysate for USP11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for USP11 | | OriGene 3'-UTR Clone for USP11 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USP11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USP11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for USP11 | | OriGene Custom Protein Services for USP11 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USP11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USP11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USP11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USP11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USP11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USP11 |
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| | | | Search Tocris compounds for USP11 |
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 | | | USP11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USP11 |
|  |  |  | | | | ThermoFisher Antibodies for USP11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USP11 |
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