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Aliases for USMG5 Gene

Aliases for USMG5 Gene

  • Up-Regulated During Skeletal Muscle Growth 5 Homolog (Mouse) 2 3 5
  • Diabetes Associated Protein In Insulin-Sensitive Tissues 2 3
  • Diabetes-Associated Protein In Insulin-Sensitive Tissues 3 4
  • HCV F-Transactivated Protein 2 3 4
  • HCVFTP2 3 4
  • DAPIT 3 4
  • Upregulated During Skeletal Muscle Growth 5 Homolog (Mouse) 2
  • Upregulated During Skeletal Muscle Growth 5 Homolog 3
  • Upregulated During Skeletal Muscle Growth 5 2
  • BA792D24.4 3

External Ids for USMG5 Gene

Previous GeneCards Identifiers for USMG5 Gene

  • GC10M104814
  • GC10M105138
  • GC10M098779

Summaries for USMG5 Gene

GeneCards Summary for USMG5 Gene

USMG5 (Up-Regulated During Skeletal Muscle Growth 5 Homolog (Mouse)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for USMG5 Gene

  • Plays a critical role in maintaining the ATP synthase population in mitochondria.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for USMG5 Gene

Genomics for USMG5 Gene

Regulatory Elements for USMG5 Gene

Enhancers for USMG5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around USMG5 on UCSC Golden Path with GeneCards custom track

Genomic Location for USMG5 Gene

103,389,041 bp from pter
103,396,513 bp from pter
7,473 bases
Minus strand

Genomic View for USMG5 Gene

Genes around USMG5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
USMG5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for USMG5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for USMG5 Gene

Proteins for USMG5 Gene

  • Protein details for USMG5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Up-regulated during skeletal muscle growth protein 5
    Protein Accession:
    Secondary Accessions:
    • B2R4N2
    • D3DR92

    Protein attributes for USMG5 Gene

    58 amino acids
    Molecular mass:
    6458 Da
    Quaternary structure:
    • Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68.

neXtProt entry for USMG5 Gene

Proteomics data for USMG5 Gene at MOPED

Post-translational modifications for USMG5 Gene

  • Ubiquitination at Lys 17
  • Modification sites at PhosphoSitePlus

Other Protein References for USMG5 Gene

No data available for DME Specific Peptides for USMG5 Gene

Domains & Families for USMG5 Gene

Protein Domains for USMG5 Gene


Suggested Antigen Peptide Sequences for USMG5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with USMG5: view

No data available for Gene Families and UniProtKB/Swiss-Prot for USMG5 Gene

Function for USMG5 Gene

Molecular function for USMG5 Gene

UniProtKB/Swiss-Prot Function:
Plays a critical role in maintaining the ATP synthase population in mitochondria.
UniProtKB/Swiss-Prot Induction:
Transactivated by SBP1.
genes like me logo Genes that share phenotypes with USMG5: view

Animal Models for USMG5 Gene

MGI Knock Outs for USMG5:

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for USMG5 Gene

Localization for USMG5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USMG5 Gene

Mitochondrion membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for USMG5 Gene COMPARTMENTS Subcellular localization image for USMG5 gene
Compartment Confidence
extracellular 5
mitochondrion 5
cytosol 3
nucleus 2
vacuole 1

Gene Ontology (GO) - Cellular Components for USMG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA --
GO:0005743 mitochondrial inner membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with USMG5: view

Pathways & Interactions for USMG5 Gene

SuperPathways for USMG5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for USMG5 Gene


No data available for Pathways by source and SIGNOR curated interactions for USMG5 Gene

Drugs & Compounds for USMG5 Gene

No Compound Related Data Available

Transcripts for USMG5 Gene

Unigene Clusters for USMG5 Gene

Up-regulated during skeletal muscle growth 5 homolog (mouse):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for USMG5 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b
SP1: - -
SP2: - -
SP3: - - -
SP4: -

Relevant External Links for USMG5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for USMG5 Gene

mRNA expression in normal human tissues for USMG5 Gene

Protein differential expression in normal tissues from HIPED for USMG5 Gene

This gene is overexpressed in Nasal epithelium (17.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for USMG5 Gene

SOURCE GeneReport for Unigene cluster for USMG5 Gene Hs.500921

genes like me logo Genes that share expression patterns with USMG5: view

Protein tissue co-expression partners for USMG5 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for USMG5 Gene

Orthologs for USMG5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for USMG5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia USMG5 35
  • 90.23 (n)
  • 94.83 (a)
USMG5 36
  • 95 (a)
USMG5 36
  • 95 (a)
(Canis familiaris)
Mammalia USMG5 35
  • 89.66 (n)
  • 89.66 (a)
USMG5 36
  • 86 (a)
(Mus musculus)
Mammalia Usmg5 35
  • 90.8 (n)
  • 89.66 (a)
Usmg5 16
Usmg5 36
  • 90 (a)
(Pan troglodytes)
Mammalia USMG5 35
  • 100 (n)
  • 100 (a)
USMG5 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Usmg5 35
  • 89.66 (n)
  • 91.38 (a)
(Monodelphis domestica)
Mammalia USMG5 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia USMG5 36
  • 77 (a)
(Gallus gallus)
Aves USMG5 36
  • 64 (a)
(Danio rerio)
Actinopterygii USMG5 36
  • 64 (a)
Species with no ortholog for USMG5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for USMG5 Gene

Gene Tree for USMG5 (if available)
Gene Tree for USMG5 (if available)

Paralogs for USMG5 Gene Pseudogenes for USMG5 Gene

genes like me logo Genes that share paralogs with USMG5: view

No data available for Paralogs for USMG5 Gene

Variants for USMG5 Gene

Sequence variations from dbSNP and Humsavar for USMG5 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs3215263 -- 103,392,642(-) TTCTT(-/A)TCAGG intron-variant
rs7093039 -- 103,389,790(+) gtagc(A/G)gcgca intron-variant
rs74663036 -- 103,390,505(+) ATATC(C/T)GGGCT intron-variant
rs74871809 -- 103,393,111(+) GGGAA(A/G)GGAAA intron-variant
rs137975343 -- 103,390,370(+) GCACC(C/T)GAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for USMG5 Gene

Variant ID Type Subtype PubMed ID
nsv7529 CNV Insertion 18451855

Variation tolerance for USMG5 Gene

Residual Variation Intolerance Score: 56.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.93; 49.05% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for USMG5 Gene

Disorders for USMG5 Gene

Relevant External Links for USMG5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for USMG5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for USMG5 Gene

Publications for USMG5 Gene

  1. Cellular and tissue expression of DAPIT, a phylogenetically conserved peptide. (PMID: 22688299) Kontro H. … Kainulainen H. (Eur J Histochem 2012) 2 3 67
  2. Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria. (PMID: 17570365) Chen R. … Walker J.E. (FEBS Lett. 2007) 2 3
  3. Identification of two proteins associated with mammalian ATP synthase. (PMID: 17575325) Meyer B. … SchAogger H. (Mol. Cell Proteomics 2007) 2 3
  4. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. (PMID: 25737280) Murn J. … Shi Y. (Genes Dev. 2015) 3
  5. Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. (PMID: 25852190) So J. … Colwill K. (Sci Signal 2015) 3

Products for USMG5 Gene

Sources for USMG5 Gene