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Aliases for USMG5 Gene

Aliases for USMG5 Gene

  • Up-Regulated During Skeletal Muscle Growth 5 Homolog (Mouse) 2 3
  • DAPIT 3 4 6
  • Diabetes-Associated Protein In Insulin-Sensitive Tissues 3 4
  • HCV F-Transactivated Protein 2 3 4
  • HCVFTP2 3 4
  • Upregulated During Skeletal Muscle Growth 5 Homolog (Mouse) 2
  • Up-Regulated During Skeletal Muscle Growth Protein 5 3
  • Upregulated During Skeletal Muscle Growth 5 Homolog 3
  • Upregulated During Skeletal Muscle Growth 5 2
  • BA792D24.4 3

External Ids for USMG5 Gene

Summaries for USMG5 Gene

GeneCards Summary for USMG5 Gene

USMG5 (Up-Regulated During Skeletal Muscle Growth 5 Homolog (Mouse)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for USMG5 Gene

  • Plays a critical role in maintaining the ATP synthase population in mitochondria.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for USMG5 Gene

Genomics for USMG5 Gene

Genomic Location for USMG5 Gene

Start:
103,389,041 bp from pter
End:
103,396,513 bp from pter
Size:
7,473 bases
Orientation:
Minus strand

Genomic View for USMG5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for USMG5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for USMG5 Gene

Regulatory Elements for USMG5 Gene

Proteins for USMG5 Gene

  • Protein details for USMG5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IX5-USMG5_HUMAN
    Recommended name:
    Up-regulated during skeletal muscle growth protein 5
    Protein Accession:
    Q96IX5
    Secondary Accessions:
    • B2R4N2
    • D3DR92

    Protein attributes for USMG5 Gene

    Size:
    58 amino acids
    Molecular mass:
    6458 Da
    Quaternary structure:
    • Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68.

neXtProt entry for USMG5 Gene

Proteomics data for USMG5 Gene at MOPED

Post-translational modifications for USMG5 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys17

Other Protein References for USMG5 Gene

No data available for DME Specific Peptides for USMG5 Gene

Domains for USMG5 Gene

Protein Domains for USMG5 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with USMG5: view

No data available for Gene Families and UniProtKB/Swiss-Prot for USMG5 Gene

Function for USMG5 Gene

Molecular function for USMG5 Gene

UniProtKB/Swiss-Prot Function: Plays a critical role in maintaining the ATP synthase population in mitochondria.
UniProtKB/Swiss-Prot Induction: Transactivated by SBP1.

Phenotypes for USMG5 Gene

GenomeRNAi human phenotypes for USMG5:
genes like me logo Genes that share phenotypes with USMG5: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for USMG5 Gene

Localization for USMG5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USMG5 Gene

Mitochondrion membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for USMG5 Gene COMPARTMENTS Subcellular localization image for USMG5 gene
Compartment Confidence
mitochondrion 5
cytosol 3
extracellular 2
nucleus 2

Gene Ontology (GO) - Cellular Components for USMG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane --
GO:0005753 mitochondrial proton-transporting ATP synthase complex ISS --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with USMG5: view

Pathways for USMG5 Gene

SuperPathways for USMG5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for USMG5 Gene

None

No data available for Pathways by source for USMG5 Gene

Transcripts for USMG5 Gene

Unigene Clusters for USMG5 Gene

Up-regulated during skeletal muscle growth 5 homolog (mouse):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for USMG5 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b
SP1: - -
SP2: - -
SP3: - - -
SP4: -

Relevant External Links for USMG5 Gene

GeneLoc Exon Structure for
USMG5
ECgene alternative splicing isoforms for
USMG5

Expression for USMG5 Gene

mRNA expression in normal human tissues for USMG5 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for USMG5 Gene

SOURCE GeneReport for Unigene cluster for USMG5 Gene Hs.500921

genes like me logo Genes that share expressions with USMG5: view

Orthologs for USMG5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for USMG5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia USMG5 36
  • 100 (n)
  • 100 (a)
USMG5 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia USMG5 36
  • 90.23 (n)
  • 94.83 (a)
USMG5 37
  • 95 (a)
OneToMany
USMG5 37
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia USMG5 36
  • 89.66 (n)
  • 89.66 (a)
USMG5 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Usmg5 36
  • 90.8 (n)
  • 89.66 (a)
Usmg5 16
Usmg5 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia USMG5 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia USMG5 37
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Usmg5 36
  • 89.66 (n)
  • 91.38 (a)
chicken
(Gallus gallus)
Aves USMG5 37
  • 64 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii USMG5 37
  • 64 (a)
OneToOne
Species with no ortholog for USMG5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for USMG5 Gene

ENSEMBL:
Gene Tree for USMG5 (if available)
TreeFam:
Gene Tree for USMG5 (if available)

Paralogs for USMG5 Gene

Pseudogenes.org Pseudogenes for USMG5 Gene

genes like me logo Genes that share paralogs with USMG5: view

No data available for Paralogs for USMG5 Gene

Variants for USMG5 Gene

Sequence variations from dbSNP and Humsavar for USMG5 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs3215263 -- 103,392,642(-) TTCTT(-/A)TCAGG intron-variant
rs4917388 -- 103,390,297(+) gagca(C/G)cctgg intron-variant
rs7093039 -- 103,389,790(+) gtagc(A/G)gcgca intron-variant
rs12770529 -- 103,389,888(+) cacca(C/T)gcccg intron-variant
rs72505131 -- 103,392,641(+) TCCTG(-/T)AAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for USMG5 Gene

Variant ID Type Subtype PubMed ID
nsv7529 CNV Insertion 18451855

Relevant External Links for USMG5 Gene

HapMap Linkage Disequilibrium report
USMG5

Disorders for USMG5 Gene

No disorders were found for USMG5 Gene.

No data available for UniProtKB/Swiss-Prot for USMG5 Gene

Publications for USMG5 Gene

  1. Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria. (PMID: 21345788) Ohsakaya S. … Yoshida M. (J. Biol. Chem. 2011) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Study of transactivating effect of pre-S2 protein of hepatitis B virus and cloning of genes transactivated by pre-S2 protein with suppression subtractive hybridization. (PMID: 16222733) Ji D. … Guo J. (World J. Gastroenterol. 2005) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3

Products for USMG5 Gene

Sources for USMG5 Gene

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