Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

USHBP1 Gene

protein-coding   GIFtS: 48
GCID: GC19M017360

Usher syndrome 1C binding protein 1
 Explore 5 diseases affiliated with
USHBP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for USHBP1    

Aliases
for USHBP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Usher Syndrome 1C Binding Protein 11 2     AIE-75-Binding Protein2 3
MCC21 2 3 5     USH1C-Binding Protein 12 3
AIEBP1 2 3     FLJ387091
Mutated In Colon Cancer Protein 22 3     AIE-75 Binding Protein Protein2
MCC-22 3     Usher Syndrome Type-1C Protein-Binding Protein 12

External Ids:    HGNC: 240581   Entrez Gene: 838782   Ensembl: ENSG000001303077   OMIM: 6118105   UniProtKB: Q8N6Y03   

Export aliases for USHBP1 gene to outside databases

Previous GC identifers: GC19M017222 GC19M017223 GC19M016927


Summaries
for USHBP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for USHBP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the USHBP1 gene promoter:
         Pax-2   MyoD   Pax-2a   NF-E2 p45   YY1   C/EBPalpha   CREB   deltaCREB   SEF-1 (1)   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: USHBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for USHBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USHBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13   Ensembl cytogenetic band:  19p13.11   HGNC chromosome: 19

USHBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USHBP1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M017360:  view genomic region     (about GC identifiers)

Start:
 17,360,838 bp from pter      End:
 17,375,573 bp from pter
Size:
 14,736 bases      Orientation:
 minus strand

Proteins
for USHBP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: USBP1_HUMAN, Q8N6Y0 (See protein sequence)
Recommended Name: Usher syndrome type-1C protein-binding protein 1  
Size: 703 amino acids; 76068 Da
Subunit: Interacts via its C-terminus with the first PDZ domain of USH1C
Sequence caution: Sequence=BAC11443.1; Type=Erroneous initiation;
Secondary accessions: Q8NBX7 Q96KH3 Q9BYI8
Alternative splicing: 2 isoforms:  Q8N6Y0-1   Q8N6Y0-2   (Due to the retention of an intron in the cDNA leading to a prematurate stop codon)

Explore the universe of human proteins at neXtProt for USHBP1: NX_Q8N6Y0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8N6Y0

    • USHBP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_114147.2  
    ENSEMBL proteins: 
     ENSP00000252597   ENSP00000407902   ENSP00000324174  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: USHBP1
    OriGene Custom Protein Services for USHBP1 
    GenScript Custom Purified and Recombinant Proteins Services for USHBP1
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for USHBP1


    USHBP1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for USHBP1 
    GenScript Custom Superior Antibodies Services for USHBP1
    Search for Antibodies for USHBP1 at Abcam  
    Uscn Antibodies for USHBP1
    Search ThermoFisher Antibodies for USHBP1

    Assay Products for USHBP1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for USHBP1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for USHBP1

    Protein Domains /
    Families
    for USHBP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    USHBP1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR019536 USH1C-bd_PDZ_domain

    Graphical View of Domain Structure for InterPro Entry Q8N6Y0

    ProtoNet protein and cluster: Q8N6Y0

    UniProtKB/Swiss-Prot: USBP1_HUMAN, Q8N6Y0
    Similarity: Belongs to the MCC family


    Function
    for USHBP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone: USHBP1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USHBP1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate USHBP1:
    hsa-miR-508-5p
    SwitchGear 3'UTR luciferase reporter plasmid: USHBP1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USHBP1 (see all 7)
    OriGene shRNA RFP: USHBP1
    OriGene siRNA: USHBP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USHBP1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for USHBP1

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: USHBP1 (NM_031941)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USHBP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USHBP1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for USHBP1
    Search LifeMap BioReagents cell lines for USHBP1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USHBP1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19060904
    GO:0030165PDZ domain binding IPI11311560


    USHBP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for USHBP1:
     Decreased homologous recombina 


    Pathways & Interactions
    for USHBP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USHBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/54 Interacting proteins for USHBP1 (Q8N6Y01, 2, 3 ENSP000002525974) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SERTAD3Q9UJW91, 3, ENSP000003254144EBI-739895,EBI-748621 I2D: score=4 STRING: ENSP00000325414
    EXOC8Q8IYI61, 3, ENSP000003535644EBI-739895,EBI-742102 I2D: score=3 STRING: ENSP00000353564
    GFI1BQ5VTD92, 3, ENSP000003447824MINT-2876995 I2D: score=3 STRING: ENSP00000344782
    USH1CQ9Y6N92, 3, ENSP000000052264MINT-58189 I2D: score=2 STRING: ENSP00000005226
    BET1O151551, 3, ENSP000002225474EBI-739895,EBI-749204 I2D: score=4 STRING: ENSP00000222547
    About this table

    Drugs & Compounds
    for USHBP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for USHBP1
    Search CenterWatch for drugs/clinical trials and news about USHBP1 / USBP1 

    Transcripts
    for USHBP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for USHBP1 gene: 
    NM_031941.3  

    Unigene Cluster for USHBP1:

    Usher syndrome 1C binding protein 1
    Hs.512773  [show with all ESTs]
    Unigene Representative Sequence: BC027910
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252597(uc002nfr.1 uc002nfs.1 uc002nft.1 uc010xpk.1)
    ENST00000431146 ENST00000324554(uc010eam.1)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: USHBP1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat USHBP1
    1 QIAGEN miScript miRNA Assays for microRNA that regulate USHBP1:
    hsa-miR-508-5p
    SwitchGear 3'UTR luciferase reporter plasmid: USHBP1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USHBP1 (see all 7)
    OriGene shRNA RFP: USHBP1
    OriGene siRNA: USHBP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USHBP1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: USHBP1 (NM_031941)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for USHBP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USHBP1 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USHBP1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USHBP1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USHBP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USHBP1

    Additional cDNA sequence: 

    AB026290.1 AK075162.1 AK096028.1 AK292031.1 AK300617.1 AK315239.1 BC027910.1 

    12 DOTS entries:

    DT.109686  DT.121502699  DT.100019656  DT.95320335  DT.100019657  DT.121502636  DT.121502653  DT.121502682 
    DT.121502718  DT.121502731  DT.121502737  DT.121502634 

    24/32 AceView cDNA sequences (see all 32):

    T32989 AI818379 BX356125 CR599813 Z40754 BI767400 AI439103 AA369348 
    BX356124 BC027910 AK096028 AB026290 BP381444 BX390279 BM923646 BQ884080 
    AA349514 NM_031941 AB040046 H80805 Z45023 BX371528 AA551913 AI864011 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for USHBP1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                    -                 -     -     -                                                                                       
    SP2:                    -                 -     -     -                                         -                                             
    SP3:                    -                 -     -                                                                                             
    SP4:                    -           -     -     -     -                                                                                       
    SP5:                    -                                                                                                                     


    ECgene alternative splicing isoforms for USHBP1

    Expression
    for USHBP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    USHBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCATAAACTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    USHBP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneZeugopod PeriosteumBone
    KidneyS-shaped BodyKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See USHBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for USHBP1

    SOURCE GeneReport for Unigene cluster: Hs.512773

    UniProtKB/Swiss-Prot: USBP1_HUMAN, Q8N6Y0
    Tissue specificity: Highest level of expression in heart, and moderate to low expression in skeletal muscle, kidney,
    liver, small intestine, placenta and lung

        SABiosciences Custom PCR Arrays for USHBP1
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USHBP1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat USHBP1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USHBP1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USHBP1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USHBP1

    Orthologs
    for USHBP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for USHBP1 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves LOC4270881 Usher syndrome type-1C protein-binding protein 1-like 49.65(n)
    36.36(a)    		   427088  XM_424682.3  XP_424682.3 
    lizard
    (Anolis carolinensis)    		 Reptilia USHBP16
    		 --
    		 30(a)
    		 1 ↔ 1
    		 GL343706.1(174463-176456)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC1001489351 Usher syndrome type-1C protein-binding protein 1-like 43.28(n)
    30.26(a)    		   100148935  XM_001921157.2  XP_001921192.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG344046
    		 --
    		 16(a)
    		 1 → many
    		 3R(11189508-11193369)


    ENSEMBL Gene Tree for USHBP1 (if available)
    TreeFam Gene Tree for USHBP1 (if available) 

    Paralogs
    for USHBP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for USHBP1 gene
    MCC2  
    1 SIMAP similar gene for USHBP1 using alignment to 5 protein entries:     USBP1_HUMAN (see all proteins):
    CNOT2

    USHBP1 for paralogs           About GeneDecksing



    Genomic Variants
    for USHBP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/365 NCBI SNPs in USHBP1 are shown (see all 365)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1407126561,2
    		--17360429(+) AATATC/TTTTAT 1 -- ds50010--------
    rs1848470051,2
    		--17360487(+) ATGGGC/GTTTTG 1 -- ds50010--------
    rs1419096941,2
    		--17360533(+) CAAGTA/GATCTA 1 -- ds50010--------
    rs1506336841,2
    		--17360576(+) AGATGA/TGCACC 1 -- ds50010--------
    rs1171484991,2
    		--17360746(+) ACCCCC/TGAAAT 1 -- ds50011Minor allele frequency- T:0.01EA 120
    rs574154721,2
    		C,--17360782(+) ATAGCC/GCAGGT 1 -- ds50012Minor allele frequency- G:0.15WA 120
    rs37451671,2
    		C,F,H,--17360864(+) TTCTTT/CATTGC 1 -- ut3120Minor allele frequency- C:0.40NS EA NA WA CSA 2342
    rs37451681,2
    		C,F,A,--17360878(+) GCCACG/ACCCCA 1 -- ut31 ese37Minor allele frequency- A:0.42WA NA CSA EA 366
    rs770941631,2
    		F,--17360894(+) CCCTGG/AACACC 1 -- ut311Minor allele frequency- A:0.03EA 120
    rs1893636781,2
    		--17360916(+) GCTTCC/TCTCAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for USHBP1 (17360838 - 17375573 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for USHBP1
         1 CNV: 30072

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USHBP1
    DNA2.0 Custom Variant and Variant Library Synthesis for USHBP1

    Disorders / Diseases
    for USHBP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    USHBP1 for disorders           About GeneDecksing

    OMIM gene information: 611810    OMIM disorders: --

    5 diseases for USHBP1:    About MalaCards
    usher syndrome    usher syndrome, type 1c    colon cancer    myeloma
    ataxia


    Export disorders for USHBP1 gene to outside databases

    Publications
    for USHBP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for USHBP1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with USHBP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain protein AIE-75. (PubMed id 11311560)1, 2, 3, 9 Ishikawa S.... Moriuchi T. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    5. Shifted Transversal Design smart-pooling for high cov erage interactome mapping. (PubMed id 19447967)1 Xin X....Thierry-Mieg N. (2009)
    6. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for USHBP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing USHBP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83878 HGNC: 24058 AceView: USHBP1 Ensembl:ENSG00000130307 euGenes: HUgn83878
    ECgene: USHBP1 H-InvDB: USHBP1

    Other Databases showing USHBP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing USHBP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for USHBP1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for USHBP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for USHBP1 gene:
    Search GeneIP for patents involving USHBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for USHBP1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for USHBP1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USHBP1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USHBP1  
     OriGene Protein Over-expression Lysate for USHBP1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for USHBP1   OriGene 3'-UTR Clone for USHBP1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USHBP1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for USHBP1   OriGene Custom Protein Services for USHBP1  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USHBP1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USHBP1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USHBP1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USHBP1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USHBP1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USHBP1
     GenScript Custom Purified and Recombinant Proteins Services for USHBP1 GenScript cDNA clones with any tag delivered in your preferred vector for USHBP1
     GenScript Custom Assay Services for USHBP1 GenScript Custom Superior Antibodies Services for USHBP1
     GenScript Custom overexpressing Cell Line Services for USHBP1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in USHBP1 promoter
     Search Chromatin IP Primers for USHBP1
     RT2 qPCR Primer Assay in human, mouse, rat USHBP1
     Search GNC Networks for USHBP1
     SABiosciences Custom PCR Arrays for USHBP1
     Search Tocris compounds for USHBP1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for USHBP1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for USHBP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     USHBP1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for USHBP1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USHBP1
     SwitchGear 3'UTR luciferase reporter plasmids for USHBP1
     SwitchGear Promoter luciferase reporter plasmids for USHBP1
     Search ThermoFisher Antibodies for USHBP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USHBP1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      USHBP1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4