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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

USH1G Gene

protein-coding   GIFtS: 56
GCID: GC17M072912

Usher Syndrome 1G (Autosomal Recessive)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Usher Syndrome 1G (Autosomal Recessive)1 2
SANS2 3 5
Scaffold Protein Containing Ankyrin Repeats And SAM Domain2 3
ANKS4A2
Usher Syndrome Type-1G Protein2

External Ids:    HGNC: 163561   Entrez Gene: 1245902   Ensembl: ENSG000001820407   OMIM: 6076965   UniProtKB: Q495M93   

Export aliases for USH1G gene to outside databases

Previous GC identifers: GC17U990308 GC17M075971 GC17M073376 GC17M073509 GC17M070423 GC17M068322


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for USH1G Gene:
This gene encodes a protein that contains three ankyrin domains, a class I PDZ-binding motif and a sterile alpha
motif. The encoded protein interacts with harmonin, which is associated with Usher syndrome type 1C. This protein
plays a role in the development and maintenance of the auditory and visual systems and functions in the cohesion
of hair bundles formed by inner ear sensory cells. Mutations in this gene are associated with Usher syndrome type
1G (USH1G). Alternative splicing results in multiple transcript variants. (provided by RefSeq, Sep 2013)

GeneCards Summary for USH1G Gene: 
USH1G (Usher syndrome 1G (autosomal recessive)) is a protein-coding gene. Diseases associated with USH1G include usher syndrome type i, and usher syndrome type 1g. GO annotations related to this gene include protein binding and protein homodimerization activity. An important paralog of this gene is ANKS4B.

UniProtKB/Swiss-Prot: USH1G_HUMAN, Q495M9
Function: Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding
protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates
mechanotransduction in cochlear hair cells. Required for normal hearing

Gene Wiki entry for USH1G Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the USH1G gene promoter:
         Nkx5-1   C/EBPalpha   CREB   CHOP-10   deltaCREB   FOXO1a   ZID   Pax-4a   FOXO1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUSH1G promoter sequence
   Search SABiosciences Chromatin IP Primers for USH1G

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USH1G


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

USH1G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
USH1G gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M072912:  view genomic region     (about GC identifiers)

Start:
72,912,176 bp from pter      End:
72,919,351 bp from pter
Size:
7,176 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: USH1G_HUMAN, Q495M9 (See protein sequence)
Recommended Name: Usher syndrome type-1G protein  
Size: 461 amino acids; 51489 Da
Subunit: Interacts with CDH23 and PCDH15; these interactions may recruit USH1G to the plasma membrane (By
similarity). Interacts with USH1C (via the first PDZ domain) and with USH1G. Interacts with PDZD7. Interacts with
MYO7A. Part of a complex composed of USH1C, USH1G and MYO7A
Subcellular location: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein (By
similarity). Note=Detected at the tip of cochlear hair cell stereocilia. Recruited to the cell membrane via
interaction with CDH23 or PCDH15 (By similarity)
3 PDB 3D structures from and Proteopedia for USH1G:
2L7T (3D)        3K1R (3D)        3PVL (3D)    
Secondary accessions: Q8N251

Explore the universe of human proteins at neXtProt for USH1G: NX_Q495M9

Explore proteomics data for USH1G at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q495M9

  • USH1G Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    USH1G Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001269418.1  NP_775748.2  

    ENSEMBL proteins: 
     ENSP00000320076   ENSP00000462568  

    Human Recombinant Protein Products for USH1G: 
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    Cloud-Clone Corp. Proteins for USH1G 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol IEA--
    GO:0005886plasma membrane IEA--
    GO:0015629actin cytoskeleton ISS12588794

    USH1G for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing
    SAMD: Sterile alpha motif (SAM) domain containing

    5 InterPro protein domains:
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR021129 SAM_type1
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q495M9

    ProtoNet protein and cluster: Q495M9

    1 Blocks protein domain: IPB001660 Sterile alpha motif SAM

    UniProtKB/Swiss-Prot: USH1G_HUMAN, Q495M9
    Similarity: Contains 3 ANK repeats
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    USH1G for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: USH1G_HUMAN, Q495M9
    Function: Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding
    protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates
    mechanotransduction in cochlear hair cells. Required for normal hearing

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19028668
    GO:0042803protein homodimerization activity IEA--
         
    USH1G for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for USH1G:
     Decreased viability with pacli  Increased cell number in G2M,  

         4 MGI mutant phenotypes (inferred from 6 alleles(MGI details for Ush1g):
     behavior/neurological  hearing/vestibular/ear  nervous system  vision/eye 

    USH1G for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ush1gtm1.2Ugds for USH1G

       inGenious Targeting Laboratory - Custom generated mouse model solutions for USH1G 
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    SwitchGear 3'UTR luciferase reporter plasmidUSH1G 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USH1G


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for USH1G

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for USH1G (Q495M92, 3 ENSP000003200764) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USH1CQ9Y6N92, 3, ENSP000000052264MINT-58187 I2D: score=1 STRING: ENSP00000005226
    MYO7AQ134023, ENSP000003863314I2D: score=1 STRING: ENSP00000386331
    --Q7RTU83I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007605sensory perception of sound IMP11398101
    GO:0042472inner ear morphogenesis IEA--
    GO:0045494photoreceptor cell maintenance IMP11398101
    GO:0050953sensory perception of light stimulus IMP11398101
    GO:0050957equilibrioception IMP12588794

    USH1G for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for USH1G

    Search CenterWatch for drugs/clinical trials and news about USH1G

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for USH1G gene (2 alternative transcripts): 
    NM_001282489.1  NM_173477.3  

    Unigene Cluster for USH1G:

    Usher syndrome 1G (autosomal recessive)
    Hs.376688  [show with all ESTs]
    Unigene Representative Sequence: NM_173477
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000319642(uc002jme.1 uc010wro.1) ENST00000579243
    miRNA
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    hsa-miR-429 hsa-miR-509-5p hsa-miR-1285 hsa-miR-4267 hsa-miR-214* hsa-miR-133a hsa-miR-891b hsa-miR-200b
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    Additional mRNA sequence: 

    AK091243.1 AK289804.1 AK296899.1 BC101096.2 BC101097.1 BC101098.2 BC101099.1 

    1 DOTS entry:

    DT.100009668 

    6 AceView cDNA sequences:

    NM_173477 AX746872 AK091243 BM045386 BM552505 BE735997 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    USH1G expression in normal human tissues (normalized intensities)      USH1G embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    USH1G Expression
    About this image


    USH1G expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Kidney (Urinary System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Oral Cavity (Gastrointestinal Tract)
             mouth   

    See USH1G Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for USH1G

    SOURCE GeneReport for Unigene cluster: Hs.376688

    UniProtKB/Swiss-Prot: USH1G_HUMAN, Q495M9
    Tissue specificity: Expressed in vestibule of the inner ear, eye and small intestine

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for USH1G gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ush1g1 , 5 Usher syndrome 1G homolog (human)5
    Usher syndrome 1G1
    90.82(n)1
    96.31(a)1
      11 (80.84 cM)5
    164701  NM_176847.31  NP_789817.11 
     1153151925 
    chicken
    (Gallus gallus)
    Aves USH1G1 Usher syndrome 1G (autosomal recessive) 76.2(n)
    77.95(a)
      428684  XM_426242.2  XP_426242.2 
    lizard
    (Anolis carolinensis)
    Reptilia USH1G6
    Uncharacterized protein
    75(a)
    1 ↔ 1
    2(115130615-115149011)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003303141 Usher syndrome type-1G protein homolog 69.44(n)
    71.55(a)
      100330314  XM_002661269.1  XP_002661315.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sans1 Sans ortholog 48.2(n)
    38.29(a)
      36427  NM_136985.2  NP_610829.1 


    ENSEMBL Gene Tree for USH1G (if available)
    TreeFam Gene Tree for USH1G (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for USH1G gene
    ANKS4B2  
    4 SIMAP similar genes for USH1G using alignment to 2 protein entries:     USH1G_HUMAN (see all proteins):
    ANKS4B    DKFZp761E1322    MTPN    ANKRD10

    USH1G for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/193 SNPs in USH1G are shown (see all 193)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0604684
    Usher syndrome 1G (USH1G)4--see VAR_0604682 D V mis40--------
    VAR_0237394
    Usher syndrome 1G (USH1G)4--see VAR_0237392 L P mis40--------
    rs1110334661,2
    C,Fnon-pathogenic174000468(-) TCCGCG/AAGGCG 2 /K /E mis13Minor allele frequency- A:0.04WA NA EU 5953
    rs1110334651,2
    C,Fnon-pathogenic174000504(-) ACCCCA/GAGCTG 2 K E mis13Minor allele frequency- G:0.04WA NA EU 5989
    rs1121256431,2
    C,F--68325738(+) GGTGGC/TAAATA 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs778154411,2
    C,F--68325767(+) TCATCG/AATGGC 1 -- int11Minor allele frequency- A:0.03EA 120
    rs1452786941,2
    --68325770(+) TCGATA/GGCCTC 1 -- int10--------
    rs1147200691,2
    F--68325830(+) GCAGAT/GCTGTA 1 -- int11Minor allele frequency- G:0.02WA 118
    rs2013596691,2
    C--68325941(+) CCTGCC/TGCCGC 2 Q R mis10--------
    rs1398975061,2
    C,F--68326023(+) GCACAG/CCATCA 2 /L /V mis11Minor allele frequency- C:0.00NA 4444

    HapMap Linkage Disequilibrium report for USH1G (72912176 - 72919351 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for USH1G:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv518292CNV Loss19592680
    nsv833540CNV Loss17160897
    nsv908744CNV Loss21882294
    dgv3254n71CNV Loss21882294
    nsv457909CNV Gain19166990


    Human Gene Mutation Database (HGMD): USH1G

    Locus Specific Mutation Databases (LSDB): USH1G
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    DNA2.0 Custom Variant and Variant Library Synthesis for USH1G

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607696   
    OMIM disorders: 606943  
    UniProtKB/Swiss-Prot: USH1G_HUMAN, Q495M9
  • Usher syndrome 1G (USH1G) [MIM:606943]: USH is a genetically heterogeneous condition characterized by the
    association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and
    vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome
    type 3 (USH3). USH1 is characterized by profound congenital sensorineural deafness, absent vestibular function
    and prepubertal onset of progressive retinitis pigmentosa leading to blindness. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 12 diseases for USH1G:    About MalaCards
    usher syndrome type i    usher syndrome type 1g    usher syndrome, type 1f    usher syndrome, type 1c
    riley-day syndrome    usher syndrome type 3    usher syndrome    retinal disease
    sensorineural hearing loss    retinitis pigmentosa    blindness    retinitis

    3 diseases from the University of Copenhagen DISEASES database for USH1G:
    Usher syndrome     Retinitis pigmentosa     Sensorineural hearing loss

    USH1G for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for USH1G gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    usher syndrome 95.6 12 17896313 (3), 20142502 (1), 16283141 (1), 19270738 (1) (see all 5)

    GeneTests: USH1G
    GeneReviews: USH1G
    Genetic Association Database (GAD): USH1G
    Human Genome Epidemiology (HuGE) Navigator: USH1G (4 documents)

    Export disorders for USH1G gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for USH1G gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with USH1G)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin. (PubMed id 12588794)1, 2, 3 Weil D.... Petit C. (2003)
    2. A novel D458V mutation in the SANS PDZ binding motif causes atypical Usher syndrome. (PubMed id 16283141)1, 2, 9 Kalay E.... Kremer H. (2005)
    3. Screening of the USH1G gene among Spanish patients with Usher syndrome. Lack of mutations and evidence of a minor role in the pathogenesis of the syndrome. (PubMed id 17896313)1, 4, 9 Aller E....Millan J. (2007)
    4. The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins. (PubMed id 20142502)1, 2, 9 Yan J....Zhang M. (2010)
    5. Structure of MyTH4-FERM domains in myosin VIIa tail b ound to cargo. (PubMed id 21311020)1, 2 Wu L....Zhang M. (2011)
    6. Simultaneous Mutation Detection in 90 Retinal Disease Genes in Multiple Patients Using a Custom-designed 300-kb Retinal Resequencing Chip. (PubMed id 20801516)1, 4 Booij J.C....Florijn R.J. (2010)
    7. Homozygous disruption of PDZD7 by reciprocal translocation in a consanguineous family: a new member of the Usher syndrome protein interactome causing congenital hearing impairment. (PubMed id 19028668)1, 2 Schneider E....Haaf T. (2009)
    8. MICROARRAY-BASED MUTATION ANALYSIS OF 183 SPANISH FAM ILIES SUFFERING FROM USHER SYNDROME. (PubMed id 19683999)1, 4 Jaijo T....Millan J.M. (2009)
    9. Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population. (PubMed id 15660226)1, 4 Ouyang X.M.... Liu X.Z. (2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 124590 HGNC: 16356 AceView: USH1G Ensembl:ENSG00000182040 euGenes: HUgn124590
    ECgene: USH1G H-InvDB: USH1G

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for USH1G Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/USH1G

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for USH1G gene:
    Search GeneIP for patents involving USH1G

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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