USB1 Gene
protein-coding GIFtS: 41
GCID: GC16P058033
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|
U6 snRNA biogenesis 1(Previous name: chromosome 16 open reading frame 57 ) (Previous symbol: C16orf57)
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Aliases for USB1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| U6 SnRNA Biogenesis 11 2 | | Chromosome 16 Open Reading Frame 571 | | C16orf571 2 3 5 | | HVSL Motif Containing 12 | | HVSL11 2 | | Mutated In Poikiloderma With Neutropenia Protein 12 | | Mpn11 2 | | Putative U6 SnRNA Phosphodiesterase2 | | HUsb11 | | U Six Biogenesis 12 | | PN2 5 | | UPF0406 Protein C16orf572 | | FLJ131541 | | EC 3.1.4.-3 |
Export aliases for USB1 gene to outside databases |
Summaries for USB1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for USB1: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in thisgene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomsonsyndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively splicedtranscript variants encoding different isoforms have been noted for this gene. (provided by RefSeq, Mar 2011) UniProtKB/Swiss-Prot: USB1_HUMAN, Q9BQ65Function: Putative phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as a ribonuclease (RNase)responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to theformation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate
|
Genomic Views for USB1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for USB1 Other transcription factors
Search SABiosciences Chromatin IP Primers for USB1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USB1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q21 Ensembl cytogenetic band: 16q21 HGNC cytogenetic band: 16q13USB1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P058033: view genomic region
(about GC identifiers)
Start:
|
58,033,450 bp from pter |
End:
|
58,055,522 bp from pter |
Size:
|
22,073 bases |
Orientation:
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plus strand |
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Proteins for USB1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: USB1_HUMAN, Q9BQ65 (See
protein sequence)Recommended Name: Putative U6 snRNA phosphodiesterase Size: 265 amino acids; 30268 Da
Subcellular location: Nucleus
1 PDB 3D structure from and Proteopedia for USB1:4H7W (3D)
 
Secondary accessions: B4DWE3 B4DZW5 Q96FZ9 Q9H8X8Alternative splicing: 3 isoforms: Q9BQ65-1 Q9BQ65-2 Q9BQ65-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for USB1: NX_Q9BQ65
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BQ65 USB1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001182231.1 NP_001191840.1 NP_078874.2 ENSEMBL proteins: ENSP00000454928 ENSP00000219281 ENSP00000446143 ENSP00000409792 ENSP00000457322 ENSP00000454692 ENSP00000457302 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
USB1 for ontologies About GeneDecksing
USB1 Antibody Products: Assay Products for USB1: |
Protein
Domains / Families for USB1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
USB1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BQ65ProtoNet protein and cluster: Q9BQ65 UniProtKB/Swiss-Prot: USB1_HUMAN, Q9BQ65Similarity: Belongs to the USB1 family |
Function for USB1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: USB1_HUMAN, Q9BQ65Function: Putative phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as a ribonuclease (RNase)responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to theformation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphateEnzyme Number (IUBMB): EC 3.1.4.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for USB1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USB1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USB1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USB1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0004518 | nuclease activity |
IEA | -- |
USB1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for USB1:
|
Pathways & Interactions for USB1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for USB1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
 2 Interacting proteins for USB1 (Q9BQ652, 3 ENSP000002192814) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
USB1 for ontologies About GeneDecksing
|
Drugs & Compounds for USB1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for USB1 Search CenterWatch for drugs/clinical trials and news about USB1 
|
Transcripts for USB1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for USB1 gene (3 alternative transcripts): NM_001195302.1 NM_001204911.1 NM_024598.3 Unigene Cluster for USB1: U6 snRNA biogenesis 1 Hs.408702 [show with all ESTs]Unigene Representative Sequence: NM_00120491116 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000561743 ENST00000219281(uc002emz.3 uc010vib.2) ENST00000539737 ENST00000423271 ENST00000561568 ENST00000565662 ENST00000566292 ENST00000569252(uc010vic.1) ENST00000562534 ENST00000568848 ENST00000563149(uc002emy.3 uc010via.2) ENST00000564387 ENST00000563207 ENST00000563321 ENST00000565151 ENST00000566082
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for USB1 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for USB1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USB1  |
Additional cDNA sequence: AK023216.1 AK124443.1 AK293220.1 AK298473.1 AK301494.1 AK303121.1 BC004415.1 BC006291.2 BC007774.2 BC010099.2 BC021554.1 15 DOTS entries: DT.113937 DT.95134812 DT.95134814 DT.70101689 DT.100707681 DT.91645193 DT.100711352 DT.100797548 DT.92450672 DT.99981502 DT.100740697 DT.100797546 DT.75113607 DT.99971494 DT.92450665 24/202 AceView cDNA sequences (see all 202): CB153912 BI907485 AI739249 AI278903 BQ882326 BU167906 BQ069736 AI954274 AI656177 AW305204 BI819525 AI281175 CD368146 BX106523 BM459994 BM543924 CD369864 AI278657 BX474597 AI216420 BU683771 BX401638 BC010099 AW304355 GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for USB1 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | |
| SP1: | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for USB1
|
Expression for USB1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot CGAP TAG: --
See USB1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for USB1
SOURCE GeneReport for Unigene cluster: Hs.408702 SABiosciences Custom PCR Arrays for USB1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USB1 Browse OriGene validated miRNA SYBR primer pairs
| |  | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat USB1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USB1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USB1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USB1 |
Orthologs for USB1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for USB1 gene from 8/26 species (see all 26) About this table
ENSEMBL Gene Tree for USB1 (if available) TreeFam Gene Tree for USB1 (if available)  |
Paralogs for USB1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for USB1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for USB1 (58033450 - 58055522 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for USB1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USB1 |
|
Disorders
/ Diseases for USB1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
USB1 for disorders About GeneDecksing
OMIM gene information: 613276 OMIM disorders: 604173 UniProtKB/Swiss-Prot: USB1_HUMAN, Q9BQ65
Defects in USB1 are the cause of poikiloderma with neutropenia (PN) [MIM:604173]. PN is a genodermatosischaracterized by poikiloderma, pachyonychia and chronic neutropenia. The disorder starts as a papular erythematousrash on the limbs during the first year of life. It gradually spreads centripetally and, as the papular rash resolves,hypo- and hyperpigmentation result, with development of telangiectasias. Another skin manifestation is pachyonychia,but alopecia and leukoplakia are distinctively absent. One of the most important extracutaneous symptoms is anincreased susceptibility to infections, mainly affecting the respiratory system, primarily due to a chronicneutropenia and to neutrophil functional defects. Bone marrow abnormalities account for neutropenia and may evolveinto myelodysplasia associated with the risk of leukemic transformation. Poikiloderma with neutropenia showsphenotypic overlap with Rothmund-Thomson syndrome 8 diseases for USB1: About MalaCardspoikiloderma with neutropenia rothmund-thomson syndrome neutropenia dyskeratosis congenita dyskeratosis leukoplakia keratosis alopecia Export disorders for USB1 gene to outside databases
|
Publications for USB1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for USB1 gene, integrated from 9 sources (see all 20): (articles sorted by number of sources associating them with USB1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- C16orf57, a gene mutated in poikiloderma with neutrope nia, encodes a putative phosphodiesterase responsible for the U6 snRNA 3' end mo dification. (PubMed id 22899009)1, 2, 3 Mroczek S....Dziembowski A. (2012)
- Identification of a homozygous deletion mutation in C 16orf57 in a family with Clericuzio-type poikiloderma with neutropenia. (PubMed id 20503306)1, 2, 3 Tanaka A....McGrath J. (2010)
- Targeted next-generation sequencing appoints c16orf57 as clericuzio-type poikiloderma with neutropenia gene. (PubMed id 20004881)1, 2, 3 Volpi L....Larizza L. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Novel C16orf57 mutations in patients with Poikiloderma with Neutropenia: bioinformatic analysis of the protein and predicted effects o f all reported mutations. (PubMed id 22269211)1 Colombo E.A....Larizza L. (2012)
- Systematic search for neutropenia should be part of t he first screening in patients with poikiloderma. (PubMed id 21872685)1 Piard J....Thauvin-Robinet C. (2012)
- Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA. (PubMed id 23022480)1 Shchepachev V....Azzalin C.M. (2012)
- Poikiloderma with neutropenia: report of three cases i ncluding one with calcinosis cutis. (PubMed id 21967010)1 Chantorn R. and Shwayder T. (2012)
- [Mutations of C16orf57 gene have been identified in t he poikiloderma-neutropenia syndrome and in a specific subset of congenital dys keratosis with normal-length telomeres]. (PubMed id 21497268)1 Dereure O. (2011)
|
External Searches for USB1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing USB1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing USB1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing USB1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for USB1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for USB1 gene: Search GeneIP for patents involving USB1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for USB1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for USB1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for USB1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for USB1 | | OriGene Protein Over-expression Lysate for USB1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for USB1 | | OriGene 3'-UTR Clone for USB1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for USB1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for USB1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for USB1 | | OriGene Custom Protein Services for USB1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat USB1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing USB1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat USB1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat USB1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat USB1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat USB1 |
| |
 |  |  |  | |
| | | Search Tocris compounds for USB1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | USB1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for USB1 |
|  |  |  | | | Search ThermoFisher Antibodies for USB1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat USB1 |
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