Aliases for UROD Gene
External Ids for UROD Gene
This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.[provided by RefSeq, Aug 2010]
GeneCards Summary for UROD Gene
UROD (Uroporphyrinogen Decarboxylase) is a Protein Coding gene. Diseases associated with UROD include cutaneous porphyria and porphyria cutanea tarda. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include uroporphyrinogen decarboxylase activity.
UniProtKB/Swiss-Prot for UROD Gene
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III