Aliases for UROC1 Gene
External Ids for UROC1 Gene
Previous GeneCards Identifiers for UROC1 Gene
This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
GeneCards Summary for UROC1 Gene
UROC1 (Urocanate Hydratase 1) is a Protein Coding gene. Diseases associated with UROC1 include urocanase deficiency and urocanic aciduria. Among its related pathways are Metabolism and Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism. GO annotations related to this gene include urocanate hydratase activity.