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Aliases for URGCP-MRPS24 Gene

Aliases for URGCP-MRPS24 Gene

  • URGCP-MRPS24 Readthrough 2 3 5

External Ids for URGCP-MRPS24 Gene

Previous GeneCards Identifiers for URGCP-MRPS24 Gene

  • GC07U903168
  • GC07M043906

Summaries for URGCP-MRPS24 Gene

Entrez Gene Summary for URGCP-MRPS24 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring URGCP (upregulator of cell proliferation) and MRPS24 (mitochondrial ribosomal protein S24) genes on chromosome 7. The read-through transcript is predicted to encode a protein that shares sequence identity with the upstream gene product but its C-terminal region is distinct due to a frameshift relative to the downstream gene. [provided by RefSeq, Mar 2011]

GeneCards Summary for URGCP-MRPS24 Gene

URGCP-MRPS24 (URGCP-MRPS24 Readthrough) is a Protein Coding gene.

Additional gene information for URGCP-MRPS24 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for URGCP-MRPS24 Gene

Genomics for URGCP-MRPS24 Gene

GeneHancer (GH) Regulatory Elements for URGCP-MRPS24 Gene

Promoters and enhancers for URGCP-MRPS24 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I043903 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 550.8 +1.1 1069 3.6 FOXA2 MLX ARID4B SIN3A DMAP1 ETS1 YY1 FOS SP3 RXRA URGCP URGCP-MRPS24 ENSG00000239556 POLM RASA4CP DBNL MRPS24
GH07I043868 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 0.3 +36.7 36740 3.5 HDGF PKNOX1 ARID4B SIN3A FEZF1 YY1 POLR2B FOS SP3 SP5 MRPS24 POLM URGCP DDX56 ENSG00000239556 ENSG00000228434 TMED4 ENSG00000241057 LINC00957 RASA4CP
GH07I043871 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +33.4 33449 2.9 MEIS2 ESRRA KLF1 PKNOX1 NFRKB JUN MAX E4F1 FOSL1 POLR2A URGCP ENSG00000239556 UBE2D4 COA1 RASA4CP MRPS24 URGCP-MRPS24
GH07I043901 Enhancer 0.4 dbSUPER 0.8 +4.9 4948 1.2 CTCF ZNF398 ENSG00000239556 POLM URGCP-MRPS24 URGCP MRPS24
GH07I043878 Enhancer 1 Ensembl ENCODE dbSUPER 0.3 +25.7 25736 4.7 PKNOX1 RXRA TEAD1 ZNF189 GLIS1 CEBPB FOS HNF4A URGCP UBE2D4 COA1 RASA4CP POLM ENSG00000241057 MRPS24 URGCP-MRPS24
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around URGCP-MRPS24 on UCSC Golden Path with GeneCards custom track

Genomic Locations for URGCP-MRPS24 Gene

Genomic Locations for URGCP-MRPS24 Gene
chr7:43,866,558-43,906,632
(GRCh38/hg38)
Size:
40,075 bases
Orientation:
Minus strand
chr7:43,906,157-43,946,231
(GRCh37/hg19)

Genomic View for URGCP-MRPS24 Gene

Genes around URGCP-MRPS24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
URGCP-MRPS24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for URGCP-MRPS24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for URGCP-MRPS24 Gene

Proteins for URGCP-MRPS24 Gene

  • Protein details for URGCP-MRPS24 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    S4R325
    Recommended name:
    URGCP-MRPS24 readthrough
    Protein Accession:
    S4R325

    Protein attributes for URGCP-MRPS24 Gene

    Size:
    110 amino acids
    Molecular mass:
    11754 Da
    Quaternary structure:
    No Data Available

neXtProt entry for URGCP-MRPS24 Gene

Post-translational modifications for URGCP-MRPS24 Gene

No Post-translational modifications

Other Protein References for URGCP-MRPS24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for URGCP-MRPS24 Gene

Domains & Families for URGCP-MRPS24 Gene

Gene Families for URGCP-MRPS24 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for URGCP-MRPS24 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with URGCP-MRPS24: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for URGCP-MRPS24 Gene

Function for URGCP-MRPS24 Gene

Phenotypes From GWAS Catalog for URGCP-MRPS24 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for URGCP-MRPS24 Gene

Localization for URGCP-MRPS24 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for URGCP-MRPS24 Gene

Pathways & Interactions for URGCP-MRPS24 Gene

SuperPathways for URGCP-MRPS24 Gene

No Data Available

Interacting Proteins for URGCP-MRPS24 Gene

Gene Ontology (GO) - Biological Process for URGCP-MRPS24 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for URGCP-MRPS24 Gene

Drugs & Compounds for URGCP-MRPS24 Gene

No Compound Related Data Available

Transcripts for URGCP-MRPS24 Gene

mRNA/cDNA for URGCP-MRPS24 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for URGCP-MRPS24 Gene

No ASD Table

Relevant External Links for URGCP-MRPS24 Gene

GeneLoc Exon Structure for
URGCP-MRPS24
ECgene alternative splicing isoforms for
URGCP-MRPS24

Expression for URGCP-MRPS24 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for URGCP-MRPS24 Gene

Orthologs for URGCP-MRPS24 Gene

Evolution for URGCP-MRPS24 Gene

ENSEMBL:
Gene Tree for URGCP-MRPS24 (if available)
TreeFam:
Gene Tree for URGCP-MRPS24 (if available)

No data available for Orthologs for URGCP-MRPS24 Gene

Paralogs for URGCP-MRPS24 Gene

(1) SIMAP similar genes for URGCP-MRPS24 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with URGCP-MRPS24: view

No data available for Paralogs for URGCP-MRPS24 Gene

Variants for URGCP-MRPS24 Gene

Sequence variations from dbSNP and Humsavar for URGCP-MRPS24 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000104388 -- 43,870,222(-) G/A intron_variant
rs1000269093 -- 43,870,798(-) C/T intron_variant
rs1000269745 -- 43,895,872(-) G/A intron_variant
rs1000342757 -- 43,867,557(-) T/A intron_variant
rs1000405676 -- 43,877,124(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for URGCP-MRPS24 Gene

Variant ID Type Subtype PubMed ID
esv3613002 CNV loss 21293372
nsv1074501 CNV deletion 25765185
nsv1145130 CNV deletion 24896259
nsv428165 CNV gain 18775914
nsv830980 CNV loss 17160897

Variation tolerance for URGCP-MRPS24 Gene

Residual Variation Intolerance Score: 59.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.29; 53.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for URGCP-MRPS24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
URGCP-MRPS24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for URGCP-MRPS24 Gene

Disorders for URGCP-MRPS24 Gene

Additional Disease Information for URGCP-MRPS24

No disorders were found for URGCP-MRPS24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for URGCP-MRPS24 Gene

Publications for URGCP-MRPS24 Gene

  1. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 58
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  3. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 58

Products for URGCP-MRPS24 Gene

Sources for URGCP-MRPS24 Gene

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