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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UQCRH Gene

protein-coding   GIFtS: 56
GCID: GC01P046769

ubiquinol-cytochrome c reductase hinge protein
 Explore 6 diseases affiliated with
UQCRH via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for UQCRH    

Aliases
for UQCRH gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ubiquinol-Cytochrome C Reductase Hinge Protein1 2     Cytochrome C1 Non-Heme 11 KDa Protein2 3
QCR61 2     Mitochondrial Hinge Protein2 3
UQCR81 2     Ubiquinol-Cytochrome C Reductase Complex 11 KDa Protein2 3
Complex III Subunit 62 3     Cytochrome B-C1 Complex Subunit 6, Mitochondrial2
Complex III Subunit VIII2 3     Ubiquinol-Cytochrome C Reductase, Complex III Subunit VIII2

External Ids:    HGNC: 125901   Entrez Gene: 73882   Ensembl: ENSG000001736607   OMIM: 6138445   UniProtKB: P079193   

Export aliases for UQCRH gene to outside databases

Previous GC identifers: GC01P046463 GC01P045726 GC01P046155 GC01P046139 GC01P046481 GC01P046541 GC01P044885


Summaries
for UQCRH gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: QCR6_HUMAN, P07919
Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex),
which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between
cytochromes c and c1

Gene Wiki entry for UQCRH


Genomic Views
for UQCRH gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UQCRH gene promoter:
         ER-alpha   p53   Tal-1   Pax-6   RREB-1   E47   YY1   GATA-2   AREB6   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UQCRH promoter sequence
   Search SABiosciences Chromatin IP Primers for UQCRH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UQCRH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34.1

UQCRH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UQCRH gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P046769:  view genomic region     (about GC identifiers)

Start:
 46,769,303 bp from pter      End:
 46,782,448 bp from pter
Size:
 13,146 bases      Orientation:
 plus strand

Proteins
for UQCRH gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: QCR6_HUMAN, P07919 (See protein sequence)
Recommended Name: Cytochrome b-c1 complex subunit 6, mitochondrial precursor  
Size: 91 amino acids; 10739 Da
Subunit: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1),
2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8,
UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1)
Subcellular location: Mitochondrion inner membrane
Secondary accessions: B2R4V9 D3DQ18 Q5TDF6 Q6LDB8 Q9BQ91

Explore the universe of human proteins at neXtProt for UQCRH: NX_P07919

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P07919

    • UQCRH Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005995.2  
    ENSEMBL proteins: 
     ENSP00000309565  
    Reactome Protein details: P07919
    Human Recombinant Protein Products: 
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    Uscn Proteins for UQCRH

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane TAS--
    GO:0005746mitochondrial respiratory chain TAS2826252
    GO:0005750mitochondrial respiratory chain complex III IEA--


    UQCRH for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for UQCRH

    Protein Domains /
    Families
    for UQCRH gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    UQCRH for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023184 Ubol_cytC_Rdtase_hinge_dom
     IPR003422 Cyt_b-c1_6

    Graphical View of Domain Structure for InterPro Entry P07919

    ProtoNet protein and cluster: P07919

    1 Blocks protein family: IPB003422 Ubiquinol-cytochrome C reductase hinge protein

    UniProtKB/Swiss-Prot: QCR6_HUMAN, P07919
    Similarity: Belongs to the UQCRH/QCR6 family


    Function
    for UQCRH gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: QCR6_HUMAN, P07919
    Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex),
    which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between
    cytochromes c and c1

    miRNA
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    Inhib. RNA
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008121ubiquinol-cytochrome-c reductase activity IEA--
    GO:0032403protein complex binding IEA--


    UQCRH for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for UQCRH:
     Decreased G3BP1 protein expres  G0/1 arrest  Increased G1 DNA content 


    Pathways & Interactions
    for UQCRH gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.1.00
    		Oxidative phosphorylation0.63
    		Respiratory electron transport0.81
    		Parkinson's disease0.61
    		Electron Transport Chain0.76
    		Alzheimer's disease0.43
    		The citric acid (TCA) cycle and respiratory electron transport0.72
    		Huntington's disease0.40
    2Metabolism
    		Metabolism1.00
    		Metabolic pathways0.38
    3Cardiac muscle contraction
    		Cardiac muscle contraction1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for UQCRH 
        Electron Transport Chain

    4        Reactome Pathways for UQCRH
        Respiratory electron transport
    Metabolism
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    The citric acid (TCA) cycle and respiratory electron transport


    5/6         Kegg Pathways  (Kegg details for UQCRH) (see all 6):
        Oxidative phosphorylation
    Metabolic pathways
    Cardiac muscle contraction
    Alzheimer's disease
    Parkinson's disease


    UQCRH for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UQCRH

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/88 Interacting proteins for UQCRH (P079193 ENSP000003095654) via UniProtKB, MINT, STRING, and/or I2D (see all 88)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYC1P085743, ENSP000003171594I2D: score=2 STRING: ENSP00000317159
    SIRT3Q9NTG73, ENSP000003721914I2D: score=2 STRING: ENSP00000372191
    COX4I1ENSP000002534524STRING: ENSP00000253452
    COX7A2LENSP000002343014STRING: ENSP00000234301
    COX8AENSP000003212604STRING: ENSP00000321260
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006119oxidative phosphorylation TAS2826252
    GO:0006122mitochondrial electron transport, ubiquinol to cytochrome c IEA--
    GO:0009060aerobic respiration TAS2826252
    GO:0022904respiratory electron transport chain TAS--
    GO:0044281small molecule metabolic process TAS--


    UQCRH for ontologies           About GeneDecksing



    Drugs & Compounds
    for UQCRH gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UQCRH

    4 HMDB Compounds for UQCRH    About this table
    CompoundSynonyms CAS #PubMed Ids
    Heme(protoporphyrinato)iron (see all 19)14875-96-8--
    QH2CoQH2 (see all 5)56275-39-9--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    8 DrugBank Compounds for UQCRH    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE-- --target--10592235
    2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol-- --target--10592235
    2-NONYL-4-HYDROXYQUINOLINE N-OXIDE-- --target--10592235
    5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole3-undecyl-2-hydroxydioxobenzothiazol (see all 4)43152-58-5target--10592235
    FAMOXADONE-- --target--10592235
    METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE-- --target--10592235
    METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE-- --target--10592235
    UBIQUINONE-2-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about UQCRH / QCR6 

    Transcripts
    for UQCRH gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for UQCRH gene: 
    NM_006004.2  

    Unigene Cluster for UQCRH:

    Ubiquinol-cytochrome c reductase hinge protein
    Hs.481571  [show with all ESTs]
    Unigene Representative Sequence: BF127835
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311672(uc001cpp.3) ENST00000489056 ENST00000486951 ENST00000496387(uc001cpq.3)
    ENST00000460947

    miRNA
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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AK311967.1 BC001426.2 BC001934.1 BC015177.1 BC093060.1 BC107703.1 BT007070.1 M36647.1 
    Y00764.1 

    24/27 DOTS entries (see all 27):

    DT.95281183  DT.95325186  DT.80100620  DT.95264706  DT.100792845  DT.121326425  DT.100685847  DT.121326476 
    DT.97760295  DT.95264675  DT.40115404  DT.95264703  DT.99949071  DT.121326544  DT.95264692  DT.121326418 
    DT.121326489  DT.121326533  DT.100685843  DT.102827459  DT.121326501  DT.91886408  DT.100685845  DT.121326342 

    24/656 AceView cDNA sequences (see all 656):

    BM971919 AI189510 BE279614 CA843945 BQ651811 AI815573 AI984516 CB996000 
    BI493651 AA922907 BU619781 BF726456 AA738347 CB139490 BM726129 BM852180 
    T27939 CD679140 BM760563 AA788658 AA843941 CB137083 AA844201 AA708433 

    GeneLoc Exon Structure


    Expression
    for UQCRH gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UQCRH expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTTTGGCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    UQCRH expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    OvaryOvigerous CordOvarian Somatic CellsOvary
    BoneZeugopod Long BoneBone
    Gut TubeMidgutGut Tube
    KidneyMetanephrosKidney
    LimbAutopodLimb
    LungTracheaLung
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See UQCRH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UQCRH

    SOURCE GeneReport for Unigene cluster: Hs.481571
        SABiosciences Expression via Pathway-Focused PCR Array including UQCRH: 
              Mitochondrial Energy Metabolism in human mouse rat

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    In Situ
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    Orthologs
    for UQCRH gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for UQCRH gene from 7/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Uqcrh1 , 5 ubiquinol-cytochrome c reductase hinge protein1, 5 84.64(n)1
    92.13(a)1    		   4 (53.10 cM)5
    665761  NM_025641.31  NP_079917.11 
     1160669655 
    chicken
    (Gallus gallus)    		 Aves UQCRH1 ubiquinol-cytochrome c reductase hinge protein 75.58(n)
    84.88(a)    		   771939  XM_001235147.2  XP_001235148.2 
    lizard
    (Anolis carolinensis)    		 Reptilia UQCRH6
    		 --
    		 80(a)
    		 1 ↔ 1
    		 4(112161782-112167398)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.49862 Xenopus laevis transcribed sequence with moderate similarity more 78.57(n)    BG729991.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.244762 Transcribed sequence with weak similarity to protein more 75.35(n)    57083328 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG303546
    Ucrh6
    		 --
    Ubiquinol-cytochrome C reductase complex 11 kDa pr...
    		 40(a)
    39(a)
    		 many → 1
    many → 1
    		 2R(4564724-4565166)
    3LHet(606165-607415)
    worm
    (Caenorhabditis elegans)    		 Secernentea T27E9.26
    		 Protein T27E9.2
    		 43(a)
    		 1 ↔ 1
    		 III(13462138-13462654)


    ENSEMBL Gene Tree for UQCRH (if available)
    TreeFam Gene Tree for UQCRH (if available) 

    Paralogs
    for UQCRH gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UQCRH gene

    UQCRH for paralogs           About GeneDecksing


    5/9 Pseudogenes.org Pseudogenes for UQCRH (see all 9)
    PGOHUM00000238757 PGOHUM00000240602 PGOHUM00000238056 PGOHUM00000243144 PGOHUM00000235901


    Genomic Variants
    for UQCRH gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/230 NCBI SNPs in UQCRH are shown (see all 230)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2014820391,2
    		--46767581(+) TCACA-/GAGCCAGC 2 -- us2k1 int10--------
    rs1926585061,2
    		--46767677(+) CCCACA/GTCGGA 2 -- int1 us2k10--------
    rs1177799271,2
    		F,--46767767(+) GTTCGC/TCCTCC 2 -- int1 us2k11Minor allele frequency- T:0.06EA 120
    rs761977671,2
    		C,--46767777(+) CCCGGC/TCGTTC 2 -- us2k1 int11Minor allele frequency- T:0.50NA 2
    rs1471661961,2
    		--46768159(+) TCGCTC/GCCGTC 2 -- int1 us2k10--------
    rs37533611,2
    		C--46768194(-) TCGGGA/GCGCCG 2 -- us2k1 int10--------
    rs15471801,2
    		C,F,A,H,--46768408(+) TGCCCC/TAGGGC 2 -- int1 us2k123Minor allele frequency- T:0.24MN NS EA NA CSA WA 2524
    rs728834251,2
    		C,--46768658(+) TTCATG/TCTCCG 2 -- us2k1 int10--------
    rs1443960301,2
    		--46768669(+) ATCCTA/GCGAGC 2 -- int1 us2k10--------
    rs2005152761,2
    		--46768748(+) GCTGGA/GCCGCC 2 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for UQCRH (46769303 - 46782448 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for UQCRH: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for UQCRH gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    UQCRH for disorders           About GeneDecksing

    OMIM gene information: 613844    OMIM disorders: --

    6 diseases for UQCRH:    About MalaCards
    soft tissue sarcoma    huntington's disease    parkinson's disease    sarcoma
    hepatocellular carcinoma    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: UQCRH (1 document)

    Export disorders for UQCRH gene to outside databases

    Publications
    for UQCRH gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UQCRH gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with UQCRH)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. An extremely acidic amino-terminal presequence of the precursor for the human mitochondrial hinge protein. (PubMed id 2826252)1, 2, 3 Ohta S.... Kagawa Y. (1987)
    2. Elevated expression of the human mitochondrial hinge protein gene in cancer. (PubMed id 7684318)1, 2, 9 Liu A.Y. and Bradner R.C. (1993)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines. (PubMed id 12881716)1, 9 Modena P....Sozzi G. (2003)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    10. Identification and characterization of proteins inter acting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effec ts of sirtuins. (PubMed id 19343720)1 Law I.K....Wang Y. (2009)

    External Searches for UQCRH gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing UQCRH gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7388 HGNC: 12590 AceView: UQCRH Ensembl:ENSG00000173660 euGenes: HUgn7388
    ECgene: UQCRH Kegg: 7388 H-InvDB: UQCRH

    Other Databases showing UQCRH gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing UQCRH gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UQCRH Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for UQCRH Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for UQCRH gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for UQCRH gene:
    Search GeneIP for patents involving UQCRH

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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