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UQCR11 Gene

protein-coding   GIFtS: 51
GCID: GC19M001597

Ubiquinol-Cytochrome C Reductase, Complex III Subunit XI

(Previous names: ubiquinol-cytochrome c reductase, 6.4kDa subunit)
(Previous symbol: UQCR)
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ubiquinol-Cytochrome C Reductase, Complex III Subunit XI1 2     Ubiquinol-Cytochrome C Reductase Complex 6.4 KDa Protein2 3
UQCR1 2 3 5     0710008D09Rik2
Complex III Subunit 101 2 3     QCR102
Ubiquinol-Cytochrome C Reductase, 6.4kDa Subunit1 2     Cytochrome B-C1 Complex Subunit 102
Complex III Subunit XI2 3     Ubiquinol Cytochrome C Reductase, 6.4kDa Subunit2

External Ids:    HGNC: 308621   Entrez Gene: 109752   Ensembl: ENSG000001275407   OMIM: 6097115   UniProtKB: O149573   

Export aliases for UQCR11 gene to outside databases

Previous GC identifer: GC19M001371


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for UQCR11 Gene:
This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part
of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur
protein in this complex. (provided by RefSeq, Oct 2009)

GeneCards Summary for UQCR11 Gene:
UQCR11 (ubiquinol-cytochrome c reductase, complex III subunit XI) is a protein-coding gene. Diseases associated with UQCR11 include huntington's disease, and fatty liver disease. GO annotations related to this gene include electron carrier activity and ubiquinol-cytochrome-c reductase activity. An important paralog of this gene is ENSG00000267059.

UniProtKB/Swiss-Prot: QCR10_HUMAN, O14957
Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1
complex), which is part of the mitochondrial respiratory chain
Function: This protein may be closely linked to the iron-sulfur protein in the complex and function as an
iron-sulfur protein binding factor




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011295.12  
Regulatory elements:
   Search for regulatory transcription factor binding sites for UQCR11
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUQCR11 promoter sequence
   Search Chromatin IP Primers for UQCR11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UQCR11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

UQCR11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UQCR11 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M001597:  view genomic region     (about GC identifiers)

Start:
1,597,154 bp from pter      End:
1,605,483 bp from pter
Size:
8,330 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: QCR10_HUMAN, O14957 (See protein sequence)
Recommended Name: Cytochrome b-c1 complex subunit 10  
Size: 56 amino acids; 6570 Da
Subunit: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and
Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6,
UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1)
Secondary accessions: B2R542 D6W5Z4 Q9UEA3 Q9UPK4

Explore the universe of human proteins at neXtProt for UQCR11: NX_O14957

Explore proteomics data for UQCR11 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys51

  • See UQCR11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006821.1  
    ENSEMBL proteins: 
     ENSP00000467262   ENSP00000467555   ENSP00000466420  
    Reactome Protein details: O14957

    UQCR11 Human Recombinant Protein Products:

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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    comIII: Mitochondrial respiratory chain complex / Complex III

    1 InterPro protein domain:
     IPR015089 UQCR

    Graphical View of Domain Structure for InterPro Entry O14957

    ProtoNet protein and cluster: O14957

    UniProtKB/Swiss-Prot: QCR10_HUMAN, O14957
    Similarity: Belongs to the UQCR11/QCR10 family


    UQCR11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: QCR10_HUMAN, O14957
    Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1
    complex), which is part of the mitochondrial respiratory chain
    Function: This protein may be closely linked to the iron-sulfur protein in the complex and function as an
    iron-sulfur protein binding factor

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008121ubiquinol-cytochrome-c reductase activity IEA--
    GO:0009055electron carrier activity TAS9161705
         
    UQCR11 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for UQCR11:
     Proliferating cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UQCR11
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UQCR11

    miRNA
    Products:
        
    miRTarBase miRNAs that target UQCR11:
    hsa-mir-615-3p (MIRT039968), hsa-mir-106b-3p (MIRT038594)

    Block miRNA regulation of human, mouse, rat UQCR11 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate UQCR11:
    hsa-miR-657 hsa-miR-155
    SwitchGear 3'UTR luciferase reporter plasmidUQCR11 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    QCR10_HUMAN, O14957: Mitochondrion inner membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol1
    extracellular1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane TAS--
    GO:0016021integral component of membrane IEA--
    GO:0070469respiratory chain IEA--

    UQCR11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for UQCR11 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
    Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.0.81
    Oxidative phosphorylation0.64
    Respiratory electron transport0.81
    Parkinson's disease0.57
    Electron Transport Chain0.75
    Huntington's disease0.45
    The citric acid (TCA) cycle and respiratory electron transport0.71
    Non-alcoholic fatty liver disease (NAFLD)0.41
    2Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    3Alzheimer's disease
    Alzheimer's disease0.44
    4Cardiac muscle contraction
    Cardiac muscle contraction

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for UQCR11
        Electron Transport Chain

    1 Reactome Pathway for UQCR11
        Respiratory electron transport


    Selected Kegg Pathways  (Kegg details for UQCR11) (see all 7):
        Oxidative phosphorylation
    Metabolic pathways
    Cardiac muscle contraction
    Non-alcoholic fatty liver disease (NAFLD)
    Alzheimer's disease


    UQCR11 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including UQCR11: 
              Mitochondrial Energy Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for UQCR11

    1 Interacting protein for UQCR11 (O149573) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYC1P085743I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006091generation of precursor metabolites and energy TAS9161705
    GO:0022904respiratory electron transport chain TAS--
    GO:0044237cellular metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    UQCR11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UQCR11 (QCR10)

    4 HMDB Compounds for UQCR11    About this table
    CompoundSynonyms CAS #PubMed Ids
    IronArmco iron (see all 19)7439-89-6--
    QH2CoQH2 (see all 5)56275-39-9--
    Ubiquinone Q1Coenzyme Q (see all 9)727-81-1--
    Ubiquinone Q22-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione (see all 7)606-06-4--

    7 DrugBank Compounds for UQCR11    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE-- --target--10592235
    2-NONYL-4-HYDROXYQUINOLINE N-OXIDE-- --target--10592235
    5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole3-undecyl-2-hydroxydioxobenzothiazol (see all 4)43152-58-5target--10592235
    FAMOXADONE-- --target--10592235
    METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE-- --target--10592235
    METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE-- --target--10592235
    UBIQUINONE-2-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UQCR11 gene: 
    NM_006830.3  

    Unigene Cluster for UQCR11:

    Ubiquinol-cytochrome c reductase, complex III subunit XI
    Hs.8372  [show with all ESTs]
    Unigene Representative Sequence: NM_006830
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000591899 ENST00000593264 ENST00000589880 ENST00000593029 ENST00000585671


    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate UQCR11:
    hsa-miR-657 hsa-miR-155
    SwitchGear 3'UTR luciferase reporter plasmidUQCR11 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat UQCR11
      QuantiFast Probe-based Assays in human, mouse, rat UQCR11

    Additional mRNA sequence: 

    AK312053.1 BC000462.2 BC003594.1 D55636.1 

    10 DOTS entries:

    DT.100797144  DT.100797139  DT.99955306  DT.100841560  DT.92436734  DT.121471064  DT.91997741  DT.92436736 
    DT.101985169  DT.95375461 

    Selected AceView cDNA sequences (see all 851):

    BQ951728 AW161860 CR601738 AI334414 BM663940 W76093 AW247856 BM559970 
    AI216756 BQ416900 BF939827 AI420139 BM042169 AA309377 BM975950 AI126393 
    CN485059 AL046370 CR593271 AA427497 AI494440 AW205720 AJ708979 BQ066010 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for UQCR11    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c
    SP1:                          -           -     -               
    SP2:                    -     -           -     -               
    SP3:                    -     -           -                     
    SP4:                                      -     -               
    SP5:                    -     -                                 


    ECgene alternative splicing isoforms for UQCR11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UQCR11 expression in normal human tissues (normalized intensities)      UQCR11 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGCGCTGTG
    UQCR11 Expression
    About this image


    UQCR11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Membranous Facial Bones
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Brain (Nervous System)
             Cerebral Cortex
    UQCR11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UQCR11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.8372
        Pathway & Disease-focused RT2 Profiler PCR Array including UQCR11: 
              Mitochondrial Energy Metabolism in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UQCR11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for UQCR11 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Uqcr111 , 5 ubiquinol-cytochrome c reductase, complex III subunit more1, 5 83.93(n)1
    83.93(a)1
      10 (39.72 cM)5
    665941  NM_025650.21  NP_079926.11 
     804029975 
    chicken
    (Gallus gallus)
    Aves UQCR116
    Gallus gallus ubiquinol-cytochrome c reductase, co...
    57(a)
    1 → many
    28(2372740-2374636)


    ENSEMBL Gene Tree for UQCR11 (if available)
    TreeFam Gene Tree for UQCR11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UQCR11 gene
    ENSG000002670592  

    UQCR11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for UQCR11
    PGOHUM00000245098


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UQCR11 (see all 232)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1448936431,2
    --1596835(+) GAGGCA/GGAGGT 1 -- ds50010--------
    rs1868623891,2
    --1596840(+) GGAGGC/TTGCAG 1 -- ds50010--------
    rs743682511,2
    C,F--1597013(+) CACACT/GTATGT 1 -- ds50011Minor allele frequency- G:0.01WA 118
    rs1899544391,2
    --1597095(+) GTGCAA/GTGTCG 1 -- ds50010--------
    rs1822064431,2
    --1597134(+) ACTGGA/GCAGCT 1 -- ds50010--------
    rs126112851,2
    C,F,H--1597302(+) agtgtT/Cgggat 1 -- ut316Minor allele frequency- C:0.21NA CSA WA EA 248
    rs1486037901,2
    C--1597324(+) CCACCA/GCTCCC 1 -- ut310--------
    rs1873130541,2
    --1597431(+) CTGCAC/TGTGGG 1 -- ut310--------
    rs1929014831,2
    --1597489(+) ATCACA/GTGAGA 1 -- ut310--------
    rs1834408071,2
    --1597636(+) TGGCTA/GTCACC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for UQCR11 (1597154 - 1605483 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for UQCR11 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3608n71CNV Loss21882294
    dgv3607n71CNV Loss21882294
    dgv3611n71CNV Loss21882294
    nsv910292CNV Loss21882294
    nsv910540CNV Loss21882294
    dgv3610n71CNV Loss21882294
    dgv3603n71CNV Loss21882294
    nsv910499CNV Loss21882294
    dgv3609n71CNV Loss21882294
    dgv3583n71CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609711    OMIM disorders: --

    7 diseases for UQCR11:    About MalaCards
    huntington's disease    fatty liver disease    renal cell carcinoma    parkinson's disease
    liver disease    alzheimer's disease    cerebritis


    UQCR11 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): UQCR11
    Human Genome Epidemiology (HuGE) Navigator: UQCR11 (1 document)

    Export disorders for UQCR11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UQCR11 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with UQCR11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Primary structure of the smallest (6.4-kDa) subunit of human and bovine ubiquinol-cytochrome c reductase deduced from cDNA sequences. (PubMed id 9161705)1, 2, 3 Islam M.M.... Tanaka M. (Biochem. Mol. Biol. Int. 1997)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (Nature 2004)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10975 HGNC: 30862 AceView: MBD3andUQCR Ensembl:ENSG00000127540 euGenes: HUgn10975
    ECgene: UQCR11 Kegg: 10975 H-InvDB: UQCR11

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UQCR11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for UQCR11 gene:
    Search GeneIP for patents involving UQCR11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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