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Aliases for UPK3BL1 Gene

Aliases for UPK3BL1 Gene

  • Uroplakin 3B Like 1 2 3
  • UPK3BL 3 4 5
  • Uroplakin-Like Protein 2 3
  • UPLP 3 4
  • Uroplakin-3b-Like Protein 3
  • Uroplakin-3-Like Protein 3
  • Uroplakin 3C Protein 3
  • Uroplakin 3B Like 2
  • Uroplakin 3B-Like 5

External Ids for UPK3BL1 Gene

Previous HGNC Symbols for UPK3BL1 Gene

  • UPK3BL

Summaries for UPK3BL1 Gene

GeneCards Summary for UPK3BL1 Gene

UPK3BL1 (Uroplakin 3B Like 1) is a Protein Coding gene. An important paralog of this gene is ENSG00000205236.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UPK3BL1 Gene

Genomics for UPK3BL1 Gene

Regulatory Elements for UPK3BL1 Gene

Enhancers for UPK3BL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G102870 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.3 -231.2 -231203 6.3 PKNOX1 FOXA2 SIN3A GATA2 ELK1 FOS SP3 JUNB PPARG TBX21 LRRC17 POLR2J3 UPK3BL1 ARMC10 ORAI2 LRWD1 RN7SKP198
GH07G102572 1.1 ENCODE 10.5 +70.1 70111 1.2 ARNT CREB3L1 SIN3A FEZF1 ZNF2 ZNF416 ZNF143 ZNF207 SP3 REST CRYZP1 ENSG00000213385 FAM185A PMPCB UPK3BL1 POLR2J2 POLR2J3 LOC102724229
GH07G101985 2.3 Ensembl ENCODE dbSUPER 4.3 +656.6 656636 1.9 HDGF PKNOX1 EBF1 ZIC2 RAD21 ZNF121 ZFHX2 POLR2A EED SCRT2 CUX1 RASA4DP UPK3BL1 GC07M101947 GC07M102004
GH07G101947 1.4 Ensembl ENCODE dbSUPER 6.7 +694.8 694791 1.6 ATF1 CBX3 TBL1XR1 NFIB ARNT INSM2 RAD21 EGR1 ZNF366 ZSCAN5C UPK3BL1 SPDYE6 ENSG00000272219 GC07P101859
GH07G102834 1.1 Ensembl ENCODE 8.5 -193.4 -193398 3.4 TBL1XR1 JUN SIN3A RAD21 HIC1 ZNF316 GATA2 ZNF366 PRDM10 ETV6 RPL23AP95 POLR2J3 UPK3BL1 RASA4DP LRWD1 ARMC10 RNU6-1136P RN7SKP198
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around UPK3BL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for UPK3BL1 Gene

Chromosome:
7
Start:
102,637,025 bp from pter
End:
102,642,791 bp from pter
Size:
5,767 bases
Orientation:
Minus strand

Genomic View for UPK3BL1 Gene

Genes around UPK3BL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UPK3BL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UPK3BL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UPK3BL1 Gene

Proteins for UPK3BL1 Gene

  • Protein details for UPK3BL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B0FP48-UPK3L_HUMAN
    Recommended name:
    Uroplakin-3b-like protein
    Protein Accession:
    B0FP48

    Protein attributes for UPK3BL1 Gene

    Size:
    263 amino acids
    Molecular mass:
    28385 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UPK3BL1 Gene

Post-translational modifications for UPK3BL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UPK3BL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UPK3BL1 Gene

Domains & Families for UPK3BL1 Gene

Protein Domains for UPK3BL1 Gene

Suggested Antigen Peptide Sequences for UPK3BL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B0FP48

UniProtKB/Swiss-Prot:

UPK3L_HUMAN :
  • Belongs to the uroplakin-3 family.
Family:
  • Belongs to the uroplakin-3 family.
genes like me logo Genes that share domains with UPK3BL1: view

No data available for Gene Families for UPK3BL1 Gene

Function for UPK3BL1 Gene

Animal Model Products

miRNA for UPK3BL1 Gene

miRTarBase miRNAs that target UPK3BL1

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UPK3BL1 Gene

Localization for UPK3BL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UPK3BL1 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for UPK3BL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with UPK3BL1: view

No data available for Subcellular locations from COMPARTMENTS for UPK3BL1 Gene

Pathways & Interactions for UPK3BL1 Gene

SuperPathways for UPK3BL1 Gene

No Data Available

Interacting Proteins for UPK3BL1 Gene

Gene Ontology (GO) - Biological Process for UPK3BL1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for UPK3BL1 Gene

Drugs & Compounds for UPK3BL1 Gene

No Compound Related Data Available

Transcripts for UPK3BL1 Gene

mRNA/cDNA for UPK3BL1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for UPK3BL1 Gene

No ASD Table

Relevant External Links for UPK3BL1 Gene

GeneLoc Exon Structure for
UPK3BL1
ECgene alternative splicing isoforms for
UPK3BL1

Expression for UPK3BL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of UPK3BL1 Gene:

UPK3BL1

Evidence on tissue expression from TISSUES for UPK3BL1 Gene

  • Eye(4)
genes like me logo Genes that share expression patterns with UPK3BL1: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for UPK3BL1 Gene

Orthologs for UPK3BL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for UPK3BL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToMany
LOC101057620 34
  • 98.86 (n)
dog
(Canis familiaris)
Mammalia UPK3BL 34
  • 78.67 (n)
-- 35
  • 68 (a)
OneToMany
cow
(Bos Taurus)
Mammalia UPK3BL 34
  • 77.96 (n)
-- 35
  • 65 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Upk3bl 34 16 35
  • 70.89 (n)
rat
(Rattus norvegicus)
Mammalia Upk3bl 34
  • 70.6 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 52 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 45 (a)
OneToMany
chicken
(Gallus gallus)
Aves UPK3BL 34
  • 51.66 (n)
-- 35
  • 38 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii upk3b 35
  • 22 (a)
OneToMany
Species where no ortholog for UPK3BL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UPK3BL1 Gene

ENSEMBL:
Gene Tree for UPK3BL1 (if available)
TreeFam:
Gene Tree for UPK3BL1 (if available)

Paralogs for UPK3BL1 Gene

Paralogs for UPK3BL1 Gene

Pseudogenes.org Pseudogenes for UPK3BL1 Gene

genes like me logo Genes that share paralogs with UPK3BL1: view

Variants for UPK3BL1 Gene

Sequence variations from dbSNP and Humsavar for UPK3BL1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10255511 -- 102,644,584(+) ATTAG(C/T)CAGTC intron-variant, upstream-variant-2KB
rs1031215080 -- 102,643,472(+) CCCCA(A/C)CCTGG intron-variant, upstream-variant-2KB
rs1043986391 -- 102,641,831(+) GGAGG(C/T)CGGGC intron-variant
rs1050237116 -- 102,640,017(+) GAGAA(A/G)AAGGA intron-variant
rs1056455109 -- 102,641,338(+) GGTTC(C/T)GAGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UPK3BL1 Gene

Variant ID Type Subtype PubMed ID
dgv11541n54 CNV loss 21841781
dgv11542n54 CNV loss 21841781
dgv11543n54 CNV loss 21841781
dgv11544n54 CNV loss 21841781
dgv11547n54 CNV loss 21841781
dgv11548n54 CNV loss 21841781
dgv11550n54 CNV loss 21841781
dgv1944e212 CNV loss 25503493
dgv23n31 CNV gain 19718026
dgv3894e59 CNV duplication 20981092
dgv3904e59 CNV duplication 20981092
dgv6538n100 CNV gain 25217958
dgv6539n100 CNV gain 25217958
dgv6540n100 CNV gain 25217958
esv27624 CNV gain+loss 19812545
esv2764015 CNV loss 21179565
esv3322158 CNV duplication 20981092
esv3353259 CNV duplication 20981092
esv3413878 CNV duplication 20981092
esv3891168 CNV gain+loss 25118596
esv3891171 CNV loss 25118596
esv7079 CNV loss 19470904
nsv1128957 CNV duplication 24896259
nsv1139905 CNV duplication 24896259
nsv1153617 CNV duplication 26484159
nsv428182 CNV gain 18775914
nsv469682 CNV gain+loss 16826518
nsv471643 CNV gain+loss 15918152
nsv482113 CNV gain 20164927
nsv499135 CNV loss 21111241
nsv509219 CNV insertion 20534489
nsv5879 CNV deletion 18451855
nsv608005 CNV gain 21841781
nsv608046 CNV loss 21841781
nsv608048 CNV loss 21841781
nsv608054 CNV loss 21841781
nsv608055 CNV gain 21841781
nsv8192 CNV gain 18304495
nsv831083 CNV loss 17160897
nsv9 CNV deletion 15895083
nsv981563 CNV duplication 23825009

Relevant External Links for UPK3BL1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UPK3BL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for UPK3BL1 Gene

Disorders for UPK3BL1 Gene

Relevant External Links for UPK3BL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UPK3BL1

No disorders were found for UPK3BL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UPK3BL1 Gene

Publications for UPK3BL1 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. Generation of divergent uroplakin tetraspanins and their partners during vertebrate evolution: identification of novel uroplakins. (PMID: 24450554) Desalle R. … Garcia-Espana A. (BMC Evol. Biol. 2014) 3 64

Products for UPK3BL1 Gene

Sources for UPK3BL1 Gene

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