UPK3BL Gene
protein-coding GIFtS: 26
GCID: GC07M102222
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uroplakin 3B-like
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Aliases
for UPK3BL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Uroplakin 3B-Like1 2 | | UPLP1 2 3 | | Uroplakin-3-Like Protein2 | | Uroplakin-3b-Like Protein2 | | Uroplakin-Like Protein2 |
Export aliases for UPK3BL gene to outside databasesPrevious GC identifers: GC07M102279 GC07M101637 |
Summaries
for UPK3BL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for UPK3BL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for UPK3BL
Other transcription factors
Search SABiosciences Chromatin IP Primers for UPK3BL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UPK3BL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1UPK3BL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M102222: view genomic region
(about GC identifiers)
Start:
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102,222,970 bp from pter |
End:
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102,283,316 bp from pter |
Size:
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60,347 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 101,637,841-101,643,607 |
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Proteins
for UPK3BL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UPK3L_HUMAN, B0FP48 (See
protein sequence)Recommended Name: Uroplakin-3b-like protein precursor Size: 263 amino acids; 28385 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)Explore the universe of human proteins at neXtProt for UPK3BL: NX_B0FP48
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_B0FP48
UPK3BL Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001107875.1
ENSEMBL proteins: ENSP00000429397
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
UPK3BL for ontologies About GeneDecksing
UPK3BL Antibody Products:
Assay Products for UPK3BL: |
Protein
Domains /
Families
for UPK3BL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UPK3BL for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry B0FP48ProtoNet protein and cluster: B0FP48 UniProtKB/Swiss-Prot: UPK3L_HUMAN, B0FP48Similarity: Belongs to the uroplakin-3 family |
Function
for UPK3BL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UPK3BL (NM_001114403) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UPK3BL | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UPK3BL |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UPK3BL |
|
Pathways & Interactions
for UPK3BL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UPK3BL
|
Drugs & Compounds
for UPK3BL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UPK3BL
Search CenterWatch for drugs/clinical trials and news about UPK3BL / UPK3L
|
Transcripts
for UPK3BL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UPK3BL gene: NM_001114403.2 1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000519541
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UPK3BL (NM_001114403) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UPK3BL | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UPK3BL |
GeneLoc Exon Structure
|
Expression
for UPK3BL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UPK3BL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for UPK3BL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UPK3BL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UPK3BL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UPK3BL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UPK3BL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UPK3BL |
Orthologs
for UPK3BL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for UPK3BL gene from 2/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UPK3BL1 |
uroplakin 3B-like |
55.15(n)
44.55(a) |
|
417514 XM_415762.3 XP_415762.3 |
zebrafish
(Danio rerio) |
Actinopterygii |
upk3l6 |
uroplakin 3l |
22(a) |
1 → many |
5(60950865-60962871) |
ENSEMBL Gene Tree for UPK3BL (if available)
TreeFam Gene Tree for UPK3BL (if available) |
Paralogs
for UPK3BL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UPK3BL gene
- UPK3B2 POLR2J32
2 SIMAP similar genes for UPK3BL using alignment to 1 protein entry: UPK3L_HUMAN:POLR2J3 UPK3B
UPK3BL for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for UPK3BL
PGOHUM00000250861
|
Genomic Variants
for UPK3BL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for UPK3BL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for UPK3BL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for UPK3BL gene integrated from 9 sources:
(articles sorted by number of sources associating them with UPK3BL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for UPK3BL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing UPK3BL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UPK3BL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UPK3BL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UPK3BL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UPK3BL gene:
Search GeneIP for patents involving UPK3BL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UPK3BL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UPK3BL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UPK3BL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UPK3BL | | | OriGene Protein Over-expression Lysate for UPK3BL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UPK3BL | | OriGene 3'-UTR Clone for UPK3BL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UPK3BL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UPK3BL | | OriGene Custom Protein Services for UPK3BL | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UPK3BL | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UPK3BL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UPK3BL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UPK3BL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UPK3BL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UPK3BL |
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| | | | Search Tocris compounds for UPK3BL |
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 | | | UPK3BL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UPK3BL |
|  |  |  | | | | Search ThermoFisher Antibodies for UPK3BL |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UPK3BL |
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