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UPK3A Gene

protein-coding   GIFtS: 56
GCID: GC22P045680

Uroplakin 3A

(Previous name: uroplakin 3)
(Previous symbol: UPK3)
  See UPK3A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Uroplakin 3A1 2     UP3A2
UPK31 2 3 5     UPIIIA2
UPIII2 3 5     uroplakin-3a2
Uroplakin III2 3     UP3a3
Uroplakin 31     

External Ids:    HGNC: 125801   Entrez Gene: 73802   Ensembl: ENSG000001003737   OMIM: 6115595   UniProtKB: O756313   

Export aliases for UPK3A gene to outside databases

Previous GC identifers: GC22P043957 GC22P044001 GC22P044059 GC22P028626


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for UPK3A Gene:
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the
apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia.
Alternatively spliced transcript variants have been described.(provided by RefSeq, Nov 2009)

GeneCards Summary for UPK3A Gene:
UPK3A (uroplakin 3A) is a protein-coding gene. Diseases associated with UPK3A include ovarian brenner tumor, and malignant ovarian brenner tumor.

UniProtKB/Swiss-Prot: UPK3A_HUMAN, O75631
Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by
terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in
terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which
may play an important role in preventing bacterial adherence (By similarity)

Gene Wiki entry for UPK3A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the UPK3A gene promoter:
         STAT5B   Pax-5   STAT5A   MIF-1   Arnt   PPAR-alpha   POU2F1   POU2F1b   POU2F1a   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUPK3A promoter sequence
   Search Chromatin IP Primers for UPK3A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UPK3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.31   Ensembl cytogenetic band:  22q13.31   HGNC cytogenetic band: 22q13.31

UPK3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UPK3A gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P045680:  view genomic region     (about GC identifiers)

Start:
45,680,863 bp from pter      End:
45,691,755 bp from pter
Size:
10,893 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: UPK3A_HUMAN, O75631 (See protein sequence)
Recommended Name: Uroplakin-3a precursor  
Size: 287 amino acids; 30670 Da
Subunit: Heterodimer with uroplakin-1B (UPK1B) (By similarity)
Secondary accessions: B0QY25 O60261 Q32N05 Q5TII6
Alternative splicing: 2 isoforms:  O75631-1   O75631-2   

Explore the universe of human proteins at neXtProt for UPK3A: NX_O75631

Explore proteomics data for UPK3A at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn74, Asn139, Asn170
  • Modification sites at PhosphoSitePlus

  • See UPK3A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001161046.1  NP_008884.1  

    ENSEMBL proteins: 
     ENSP00000216211   ENSP00000379391  

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    antibodies-online proteins for UPK3A (7 products) 

     
    antibodies-online peptides for UPK3A

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR024825 Uroplakin-3a
     IPR024831 Uroplakin-3

    Graphical View of Domain Structure for InterPro Entry O75631

    ProtoNet protein and cluster: O75631

    UniProtKB/Swiss-Prot: UPK3A_HUMAN, O75631
    Similarity: Belongs to the uroplakin-3 family


    Find genes that share domains with UPK3A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UPK3A_HUMAN, O75631
    Function: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by
    terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in
    terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which
    may play an important role in preventing bacterial adherence (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for UPK3A:

     Decreased Hepatitis C virus re 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Upk3a):
     homeostasis/metabolism  renal/urinary system 

    Find genes that share phenotypes with UPK3A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Upk3atm1Tsun for UPK3A

       genOway: Develop your customized and physiologically relevant rodent model for UPK3A

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UPK3A_HUMAN, O75631: Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity).
    Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER) (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    extracellular2
    plasma membrane2
    cytoskeleton1
    cytosol1
    lysosome1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--
    GO:0016324apical plasma membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with UPK3A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UPK3A
    Interactions:

        Search GeneGlobe Interaction Network for UPK3A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for UPK3A (O756313 ENSP000002162114) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UPK1BO758413, ENSP000002642344I2D: score=2 STRING: ENSP00000264234
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000902cell morphogenesis IEA--
    GO:0001822kidney development IEA--
    GO:0006833water transport IEA--
    GO:0015840urea transport IEA--
    GO:0030855epithelial cell differentiation IDA10514386

    Find genes that share ontologies with UPK3A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UPK3A



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for UPK3A gene (2 alternative transcripts): 
    NM_001167574.1  NM_006953.3  

    Unigene Cluster for UPK3A:

    Uroplakin 3A
    Hs.632787  [show with all ESTs]
    Unigene Representative Sequence: AF085808
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216211(uc003bfy.3 uc010gzy.3) ENST00000396082
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    Additional mRNA sequence: 

    AB010116.1 AB010637.1 AF085808.1 BC069544.1 BC108900.2 CR456608.1 

    2 DOTS entries:

    DT.65288373  DT.99950089 

    20 AceView cDNA sequences:

    NM_006953 BC069544 BV184428 AF085808 CR456608 BM681088 AB010116 BM727658 
    AB010637 BX116212 BU597796 BF447256 BF477659 AW138632 AA658105 AA513520 
    AW204813 AW204609 AI928252 BU930300 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for UPK3A    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:                                          
    SP2:              -     -                     


    ECgene alternative splicing isoforms for UPK3A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UPK3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGAGTTCTG
    UPK3A Expression
    About this image


    UPK3A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Kidney (Urinary System)    fully expand to see all 4 entries
             Ureteric Bud Cells Ureteric Bud
             Metanephros
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Prostate (Endocrine System)
    UPK3A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UPK3A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632787

    UniProtKB/Swiss-Prot: UPK3A_HUMAN, O75631
    Tissue specificity: Expressed in ureter

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for UPK3A gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Upk3a1 , 5 uroplakin 3A1, 5 84.04(n)1
    84.15(a)1
      15 (40.25 cM)5
    222701  NM_023478.21  NP_075967.21 
     850171415 
    chicken
    (Gallus gallus)
    Aves UPK3A1 uroplakin 3A 56.4(n)
    51.2(a)
      418242  XM_004938042.1  XP_004938099.1 
    lizard
    (Anolis carolinensis)
    Reptilia UPK3A6
    uroplakin 3A
    52(a)
    1 ↔ 1
    5(84385789-84395725)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia upk3a1 uroplakin 3A 51.4(n)
    41.6(a)
      394575  NM_203647.1  NP_988978.2 


    ENSEMBL Gene Tree for UPK3A (if available)
    TreeFam Gene Tree for UPK3A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UPK3A (see all 402)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1219181861,2,,4
    C,FRenal adysplasia (RADYS)4 pathogenic129608474(+) GGGGCC/TGCCAC 4 P L mis12Minor allele frequency- T:0.00NA EU 5727
    VAR_0444004
    Renal adysplasia (RADYS)4--see VAR_0444002 G D mis40--------
    rs622311321,2
    C,F--29595798(+) TCACTA/GTGTTG 2 -- us2k16Minor allele frequency- G:0.18NA WA CSA 11
    rs622311331,2
    C,F--29595903(+) AAAGAC/TTTTTA 2 -- us2k17Minor allele frequency- T:0.45NA WA CSA EA 250
    rs752057151,2
    C,F--29595917(+) ATCAAG/AGGCCG 2 -- us2k12Minor allele frequency- A:0.07NA EA 240
    rs1929394881,2
    --29595921(+) AGGGCC/TGGGCG 2 -- us2k10--------
    rs1413058581,2
    --29596078(+) TGCCTA/GTAGTC 2 -- us2k10--------
    rs121720571,2
    C,F,H--29596118(+) atggcG/Atgaac 2 -- us2k18Minor allele frequency- A:0.02NS EA NA WA 428
    rs121725441,2
    C--29596149(+) tgagcG/Cgagat 2 -- us2k14Minor allele frequency- C:0.12NA WA 8
    rs1420677531,2
    C--29596158(+) ATCACC/GCCACT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for UPK3A (45680863 - 45691755 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for UPK3A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv508741CNV Insertion20534489
    nsv829278CNV Loss20364138
    esv34218CNV Gain17911159
    nsv9921CNV Gain+Loss18304495
    dgv1411e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): UPK3A
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611559    OMIM disorders: --

    UniProtKB/Swiss-Prot: UPK3A_HUMAN, O75631
  • Renal adysplasia (RADYS) [MIM:191830]: Renal agenesis refers to the absence of one (unilateral) or both
    (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases,
    including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe
    obstructive uropathy. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 11 diseases for UPK3A:    
    About MalaCards
    ovarian brenner tumor    malignant ovarian brenner tumor    upk3a-related renal adysplasia    bladder carcinoma
    renal hypodysplasia/aplasia 1    renal hypoplasia, isolated    prostate adenocarcinoma    vesicoureteral reflux
    renal agenesis    unilateral renal agenesis    nephrogenic adenoma

    6 diseases from the University of Copenhagen DISEASES database for UPK3A:
    Vesicoureteral reflux     Ovarian Brenner tumor     Malignant ovarian Brenner tumor     Urinary bladder cancer
    Nephrogenic adenoma     Carcinoma

    Find genes that share disorders with UPK3A           About GenesLikeMe

    9 Novoseek inferred disease relationships for UPK3A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    brenner tumor 85.2 3 10800401 (1), 11253121 (1), 19769199 (1)
    carcinoma transitional cell 70.7 3 12502922 (1), 12474225 (1), 7511294 (1)
    vesicoureteral reflux 59.2 3 14713856 (1), 15523493 (1)
    bladder carcinoma 56.5 1 18949075 (1)
    bladder cancer 49.6 1 18313120 (1)
    carcinoma 46.5 11 10800401 (4), 16686732 (3), 14654529 (1), 14654522 (1) (see all 5)
    metastasis 40.9 4 10800401 (1), 12474225 (1), 7511294 (1), 16686732 (1)
    tumors 25.4 5 15626916 (1), 12502922 (1), 10800401 (1), 14576476 (1) (see all 5)
    adenocarcinoma 18.9 1 16086826 (1)

    Genetic Association Database (GAD): UPK3A
    Human Genome Epidemiology (HuGE) Navigator: UPK3A (2 documents)

    Export disorders for UPK3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UPK3A gene, integrated from 10 sources (see all 56):
    (articles sorted by number of sources associating them with UPK3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression of uroplakin Ib and uroplakin III genes in tissues and peripheral blood of patients with transitional cell carcinoma. (PubMed id 9818021)1, 2, 3 Yuasa T.... Okada Y. (Jpn. J. Cancer Res. 1998)
    2. Uroplakin gene expression by normal and neoplastic human urothelium. (PubMed id 9846985)1, 2, 9 Lobban E.D.... Southgate J. (Am. J. Pathol. 1998)
    3. Whole-genome linkage and association scan in primary, nonsyndromic vesicoureteric reflux. (PubMed id 19959718)1, 4 Cordell H.J....Goodship J.A. (J. Am. Soc. Nephrol. 2010)
    4. Mutations in Uroplakin IIIA are a rare cause of renal hypodysplasia in humans. (PubMed id 16731295)1, 2 Schoenfelder E.-M.... Weber S. (Am. J. Kidney Dis. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    7. Up-regulation of urinary UPIII mRNA levels in vesicoureteral reflux patients: potential application as a screening test for vesicoureteral reflux. (PubMed id 17880289)1, 9 Iwaki H....Yoshiki T. (Int. J. Urol. 2007)
    8. Uroplakin III-delta4 messenger RNA as a promising marker to identify nonulcerative interstitial cystitis. (PubMed id 17698128)1, 9 Zeng Y....Kakehi Y. (J. Urol. 2007)
    9. No pathogenic mutations in the uroplakin III gene of 25 patients with primary vesicoureteral reflux. (PubMed id 14713856)1, 9 Giltay J.C....de Jong T.P. (J. Urol. 2004)
    10. Uroplakin gene expression in normal human tissues and locally advanced bladder cancer. (PubMed id 12474225)1, 9 Olsburgh J....Southgate J. (J. Pathol. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7380 HGNC: 12580 AceView: UPK3A Ensembl:ENSG00000100373 euGenes: HUgn7380
    ECgene: UPK3A H-InvDB: UPK3A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UPK3A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UPK3A gene:
    Search GeneIP for patents involving UPK3A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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