Aliases for UPK3A Gene
External Ids for UPK3A Gene
Previous HGNC Symbols for UPK3A Gene
Previous GeneCards Identifiers for UPK3A Gene
This gene encodes a member of the uroplakin family, a group of transmembrane proteins that form complexes on the apical surface of the bladder epithelium. Mutations in this gene may be associated with renal adysplasia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
GeneCards Summary for UPK3A Gene
UniProtKB/Swiss-Prot for UPK3A Gene
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).