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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UNKL Gene

protein-coding   GIFtS: 48
GCID: GC16M001427

unkempt homolog (Drosophila)-like

(Previous name: chromosome 16 open reading frame 28 )
(Previous symbol: C16orf28)
  Search for UNKL
in
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our new
 Human Malady Compendium 
Biological research products
for UNKL    

Aliases
for UNKL gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Unkempt Homolog (Drosophila)-Like1 2     RING Finger Protein Unkempt-Like2 3
C16orf281 2 3     FLJ233601
ZC3H5L1 2 3     Chromosome 16 Open Reading Frame 281
ZC3HDC5L1 2 3     Putative E3 Ubiquitin-Protein Ligase UNKL2
Zinc Finger CCCH Domain-Containing Protein 5-Like2 3     EC 6.3.2.-3

External Ids:    HGNC: 141841   Entrez Gene: 647182   Ensembl: ENSG000000591457   UniProtKB: Q9H9P53   

Export aliases for UNKL gene to outside databases

Previous GC identifers: GC16M001449 GC16M001373 GC16M001358 GC16M001414 GC16M001343 GC16M001418 GC16M001419 GC16M001420 GC16M001422


Summaries
for UNKL gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: UNKL_HUMAN, Q9H9P5
Function: May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is
directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not
been proven

Gene Wiki entry for UNKL


Genomic Views
for UNKL gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UNKL gene promoter:
         AML1a   Egr-1   FOXL1   Arnt   AREB6   PPAR-gamma1   PPAR-gamma2   ATF6   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): UNKL promoter sequence
   Search SABiosciences Chromatin IP Primers for UNKL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNKL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

UNKL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UNKL gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M001427:  view genomic region     (about GC identifiers)

Start:
 1,413,206 bp from pter      End:
 1,464,752 bp from pter
Size:
 51,547 bases      Orientation:
 minus strand

Proteins
for UNKL gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: UNKL_HUMAN, Q9H9P5 (See protein sequence)
Recommended Name: Putative E3 ubiquitin-protein ligase UNKL  
Size: 680 amino acids; 73828 Da
Subunit: Isoform 4 (C-terminal) interacts with the GTP-bound form of RAC1. Isoform 4 (C-terminal) interacts with
SMARCD2/BAF60b
Subcellular location: Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 is primarily localized in the cytoplasm but has the
ability to shuttle between the nucleus and the cytoplasm
Caution: Was termed (PubMed:20148946) Unkempt
Secondary accessions: B0QYN6 B1GXI8 Q96EV1 Q96RZ1 Q9BWL5 Q9H5K0 Q9UJJ8
Alternative splicing: 6 isoforms:  Q9H9P5-4   Q9H9P5-1   Q9H9P5-2   Q9H9P5-3   Q9H9P5-5   Q9H9P5-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UNKL: NX_Q9H9P5

Post-translational modifications:

  • Isoform 4 is ubiquitinated in the C-terminal. Ubiquitination is enhanced by activated RAC1. The presence of the RING
    • finger domain is not essential for ubiquitination to occur1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H9P5

    • UNKL Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001032202.1  NP_001180317.2  NP_001180318.1  NP_001263343.1  NP_075564.3  

    ENSEMBL proteins: 
     ENSP00000248104   ENSP00000380606   ENSP00000422852   ENSP00000384850   ENSP00000423107  
     ENSP00000372205   ENSP00000301712   ENSP00000373873   ENSP00000385895   ENSP00000375763  
     ENSP00000380604  

    Human Recombinant Protein Products: 
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    OriGene Purified Protein: UNKL
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    Novus Biologicals UNKL Proteins
    Novus Biologicals UNKL Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for UNKL

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--


    UNKL for ontologies           About GeneDecksing



    UNKL Antibody Products: 
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    Uscn ELISAs and CLIAs for UNKL

    Protein Domains /
    Families
    for UNKL gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    UNKL for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000571 Znf_CCCH
     IPR001841 Znf_RING

    Graphical View of Domain Structure for InterPro Entry Q9H9P5

    ProtoNet protein and cluster: Q9H9P5

    1 Blocks protein family: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: UNKL_HUMAN, Q9H9P5
    Domain: Although this protein contains a RING domain, intrinsic E3 ligase activity has not been proven
    (PubMed:20148946)
    Similarity: Belongs to the unkempt family
    Similarity: Contains 4 C3H1-type zinc fingers
    Similarity: Contains 1 RING-type zinc finger


    Function
    for UNKL gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: UNKL_HUMAN, Q9H9P5
    Function: May participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is
    directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not
    been proven

    Enzyme Number (IUBMB): EC 6.3.2.-1

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNKL
    8/102 QIAGEN miScript miRNA Assays for microRNAs that regulate UNKL (see all 102):
    hsa-miR-3607-3p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-30d hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): UNKL 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UNKL (see all 4)
    OriGene shRNA RFP: UNKL
    OriGene siRNA: UNKL
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNKL

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for UNKL

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UNKL 

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    Search LifeMap BioReagents cell lines for UNKL

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--


    UNKL for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for UNKL:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for UNKL gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: UNKL_HUMAN, Q9H9P5
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UNKL

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/11 Interacting proteins for UNKL (Q9H9P53 ENSP000003017124) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    HECAQ9UBI93I2D: score=5 
    SMAD1Q157973I2D: score=3 
    SMAD2Q157963I2D: score=3 
    RAC1P630003I2D: score=2 
    SMARCD2Q929253I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--


    UNKL for ontologies           About GeneDecksing



    Drugs & Compounds
    for UNKL gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UNKL
    Search CenterWatch for drugs/clinical trials and news about UNKL 

    Transcripts
    for UNKL gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for UNKL gene (5 alternative transcripts): 
    NM_001037125.2  NM_001193388.2  NM_001193389.1  NM_001276414.1  NM_023076.4  

    Unigene Cluster for UNKL:

    Unkempt homolog (Drosophila)-like
    Hs.643536  [show with all ESTs]
    Unigene Representative Sequence: NM_001193388
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000248104(uc002clo.3) ENST00000562537 ENST00000397464 ENST00000508903
    ENST00000402641 ENST00000511095 ENST00000513783 ENST00000563572 ENST00000515195
    ENST00000382757 ENST00000509981 ENST00000301712(uc002clq.3) ENST00000502438
    ENST00000503648 ENST00000566707 ENST00000561783 ENST00000389221(uc010brn.2)
    ENST00000403703(uc002cln.3 uc002clp.3)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNKL
    8/102 QIAGEN miScript miRNA Assays for microRNAs that regulate UNKL (see all 102):
    hsa-miR-3607-3p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-199a-3p hsa-miR-128 hsa-miR-30d hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmids (see all 2): UNKL 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UNKL (see all 4)
    OriGene shRNA RFP: UNKL
    OriGene siRNA: UNKL
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNKL
    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNKL

    Additional cDNA sequence: 

    AK022685.1 AK024842.1 AK027013.1 AK124977.1 AM944365.1 BC000150.1 BC011924.2 

    15 DOTS entries:

    DT.97836038  DT.101979057  DT.75101053  DT.209076  DT.100748271  DT.120662060  DT.92416459  DT.100681107 
    DT.120662126  DT.316570  DT.91936791  DT.120662105  DT.75171129  DT.95329673  DT.97778974 

    20 AceView cDNA sequences:

    NM_024023 AK124977 NM_023076 CD675420 AI400804 AK022685 BC000150 AK027013 
    BF513084 AK024842 AW592111 BC011924 BF115402 AA760804 CF136587 AW971542 
    BG059385 H92871 BF943831 CD631744 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for UNKL    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:                                                                        
    SP2:                                                  -                     
    SP3:                                                  -     -               
    SP4:                    -                                                   
    SP5:                                                  -     -     -         


    ECgene alternative splicing isoforms for UNKL

    Expression
    for UNKL gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UNKL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGTTATTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    UNKL expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryAntral FollicleSecondary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See UNKL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UNKL

    SOURCE GeneReport for Unigene cluster: Hs.643536
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    In Situ
    Assay Products:     
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    Orthologs
    for UNKL gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for UNKL gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Unkl1 , 5 unkempt-like (Drosophila)1, 5 82.72(n)1
    88.44(a)1    		   17 (12.53 cM)5
    741541  NM_001197024.11  NP_001183953.11 
     251883975 
    chicken
    (Gallus gallus)    		 Aves UNKL1 unkempt homolog (Drosophila)-like 64.41(n)
    70.1(a)    		   416593  XM_414893.3  XP_414893.3 
    zebrafish
    (Danio rerio)    		 Actinopterygii unkl1 unkempt homolog (Drosophila)-like 66.47(n)
    68.9(a)    		   565405  XM_688685.5  XP_693777.5 
    fruit fly
    (Drosophila melanogaster)    		 Insecta unk6
    		 unkempt
    		 36(a)
    		 1 → many
    		 3R(18975963-18983592)
    worm
    (Caenorhabditis elegans)    		 Secernentea C34D10.26
    		 Protein C34D10.2
    		 31(a)
    		 possible ortholog
    		 X(8017972-8025841)


    ENSEMBL Gene Tree for UNKL (if available)
    TreeFam Gene Tree for UNKL (if available) 

    Paralogs
    for UNKL gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UNKL gene
    UNK2  
    1 SIMAP similar gene for UNKL using alignment to 4 protein entries:     UNKL_HUMAN (see all proteins):
    UNK

    UNKL for paralogs           About GeneDecksing



    Genomic Variants
    for UNKL gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1215 NCBI SNPs in UNKL are shown (see all 1215)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs600004151,2
    		--1341555(+) GACCCG/TCAGGG 1 -- ut310--------
    rs71924081,2
    		C,F,--1341711(+) AACTTT/CAAACA 1 -- ut311Minor allele frequency- C:0.08WA 118
    rs1163458261,2
    		C,F,--1341822(+) NNNNAG/AAAATT 1 -- ds50013Minor allele frequency- A:0.08WA NA EA 358
    rs560266281,2
    		C,F,--1342091(+) CCTGAG/AGCCAT 1 -- ds50011Minor allele frequency- A:0.04WA 118
    rs20642921,2
    		A--1350689(+) GCGTGC/GAGCAC 1 -- int10--------
    rs2012635371,2
    		C,--1412748(+) GGTACC/TGTATT 4 -- int1 ds50011Minor allele frequency- T:0.00EU 1251
    rs2002393981,2
    		--1412771(+) TGGCAC/TGCAGT 4 -- ds5001 int10--------
    rs1383322651,2
    		--1412786(+) CTCCAC/GCACCT 4 -- int1 ds50010--------
    rs1997247651,2
    		--1412823(+) GTTGGC/TAGGCT 4 -- int1 ds50010--------
    rs768274911,2
    		C--1412961(+) CTGTGA/GGTCCA 4 -- ds5001 int10--------

    HapMap Linkage Disequilibrium report for UNKL (1413206 - 1464752 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 13 variations for UNKL
         11 CNVs: 29996 29991 102198 29997 59561 5329 4779 61487 59562 72418 43330
         2 Indels: 59560 59559
    Human Gene Mutation Database (HGMD): UNKL

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for UNKL gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    UNKL for disorders           About MalaCards

    UNKL for disorders           About GeneDecksing


    Export disorders for UNKL gene to outside databases

    Publications
    for UNKL gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UNKL gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with UNKL)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt. (PubMed id 20148946)1, 2 LorA"s P....Gacon G. (2010)
    2. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    7. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (2005)
    8. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    External Searches for UNKL gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing UNKL gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64718 HGNC: 14184 AceView: UNKLandC16orf28 Ensembl:ENSG00000059145 euGenes: HUgn64718
    ECgene: UNKL H-InvDB: UNKL

    Other Databases showing UNKL gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing UNKL gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UNKL Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for UNKL gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for UNKL gene:
    Search GeneIP for patents involving UNKL

    GeneCards and IP:
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