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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UNK Gene

protein-coding   GIFtS: 47
GCID: GC17P073780

Unkempt Homolog (Drosophila)

(Previous names: zinc finger CCCH-type domain containing 5, zinc finger CCCH-type...)
(Previous symbols: ZC3HDC5, ZC3H5)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Unkempt Homolog (Drosophila)1 2     Zinc Finger CCCH Domain-Containing Protein 52 3
ZC3H51 2 3     RING Finger Protein Unkempt Homolog2
ZC3HDC51 2 3     Zinc Finger CCCH Type Domain Containing 52
Zinc Finger CCCH-Type Containing 51 2     KIAA17533
Zinc Finger CCCH-Type Domain Containing 51 2     H5

External Ids:    HGNC: 293691   Entrez Gene: 854512   Ensembl: ENSG000001324787   OMIM: 6065325   UniProtKB: Q9C0B03   

Export aliases for UNK gene to outside databases

Previous GC identifers: GC17P071293 GC17P069206


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for UNK Gene: 
UNK (unkempt homolog (Drosophila)) is a protein-coding gene. Diseases associated with UNK include eclampsia, and pre-eclampsia. GO annotations related to this gene include zinc ion binding and nucleic acid binding. An important paralog of this gene is UNKL.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UNK gene promoter:
         Sox5   AML1a   AP-4   Arnt   Egr-4   Pax-3   HSF2   MRF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for UNK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.3

UNK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UNK gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P073780:  view genomic region     (about GC identifiers)

Start:
73,780,681 bp from pter      End:
73,821,886 bp from pter
Size:
41,206 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UNK_HUMAN, Q9C0B0 (See protein sequence)
Recommended Name: RING finger protein unkempt homolog  
Size: 810 amino acids; 88084 Da
Sequence caution: Sequence=AAH53362.1; Type=Erroneous initiation; Sequence=BAB21844.1; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for UNK: NX_Q9C0B0

Explore proteomics data for UNK at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9C0B0

  • UNK Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    UNK Protein Expression
    REFSEQ proteins: NP_001073888.2  
    ENSEMBL proteins: 
     ENSP00000464893   ENSP00000464953   ENSP00000467849   ENSP00000466431   ENSP00000466054  
     ENSP00000467726   ENSP00000293218  

    Human Recombinant Protein Products for UNK: 
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    OriGene Protein Over-expression Lysate for UNK
    OriGene Custom MassSpec 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UNK 


    UNK Antibody Products: 
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    Novus Biologicals UNK Antibodies
    Abcam antibodies for UNK
    Cloud-Clone Corp. Antibodies for UNK 
    ThermoFisher Antibodies for UNK
    LSBio Antibodies in human, mouse, rat for UNK 

    Assay Products for UNK: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for UNK
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for UNK
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for UNK 
    Cloud-Clone Corp. CLIAs for UNK


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZC3H: Zinc fingers, CCCH-type domain containing

    2 InterPro protein domains:
     IPR000571 Znf_CCCH
     IPR001841 Znf_RING

    Graphical View of Domain Structure for InterPro Entry Q9C0B0

    ProtoNet protein and cluster: Q9C0B0

    2 Blocks protein domains:
    IPB000571 Zn-finger
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: UNK_HUMAN, Q9C0B0
    Similarity: Belongs to the unkempt family
    Similarity: Contains 5 C3H1-type zinc fingers
    Similarity: Contains 1 RING-type zinc finger


    UNK for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    UNK for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for UNK 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for UNK

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UNK 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UNK 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNK
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate UNK (see all 61):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-517a hsa-miR-106a hsa-miR-517c hsa-miR-29a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for UNK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNK

    Gene Editing
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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for UNK (see all 8)
    OriGene ORF clones in mouse, rat for UNK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNK (NM_014586)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNK
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNK
    Sirion Biotech Customized lentivirus for stable overexpression of UNK 
                         Customized lentivirus expression plasmids for stable overexpression of UNK 

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    Search LifeMap BioReagents cell lines for UNK
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNK


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UNK

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for UNK (Q9C0B02, 3 ENSP000002932184) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2877796 I2D: score=2 STRING: ENSP00000244769
    PAX8Q067103I2D: score=1 
    MTORENSP000003545584STRING: ENSP00000354558
    RPTORENSP000003072724STRING: ENSP00000307272
    MLST8ENSP000003718884STRING: ENSP00000371888
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UNK

    Search CenterWatch for drugs/clinical trials and news about UNK

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for UNK gene: 
    NM_001080419.2  

    Unigene Clusters for UNK:

    Unkempt homolog (Drosophila)
    Hs.584768  [show with all ESTs], Hs.732048  [show with all ESTs]
    Unigene Representative Sequences: NM_001080419, AK096931
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589666 ENST00000589790 ENST00000587501 ENST00000586527 ENST00000592629
    ENST00000592074 ENST00000586217 ENST00000587258 ENST00000293218(uc002jpm.3 uc002jpn.3 uc002jpo.3 uc021udd.1)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNK
    8/61 QIAGEN miScript miRNA Assays for microRNAs that regulate UNK (see all 61):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-517a hsa-miR-106a hsa-miR-517c hsa-miR-29a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for UNK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNK
    Clone
    Products:
         
    OriGene clones in human, mouse for UNK (see all 8)
    OriGene ORF clones in mouse, rat for UNK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNK (NM_014586)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNK
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNK
    Sirion Biotech Customized lentivirus for stable overexpression of UNK 
                         Customized lentivirus expression plasmids for stable overexpression of UNK 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for UNK
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNK
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNK
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNK

    Additional mRNA sequence: 

    AK096931.1 AK307289.1 BC033751.1 BC039606.1 BC046175.1 BC064927.1 BC080657.1 NR_038131.1 

    13 DOTS entries:

    DT.308728  DT.100670268  DT.110885  DT.95201585  DT.95262902  DT.95307175  DT.100702421  DT.100750042 
    DT.102842502  DT.91684837  DT.91740658  DT.40223296  DT.99930640 

    24/141 AceView cDNA sequences (see all 141):

    BM975496 AA866166 AB051540 BQ433050 AI290504 Z43055 CR591163 BU170398 
    AA872706 N46675 CB242820 BU181655 BM664266 BI465073 F05490 CA312134 
    BX114359 AA886979 CA438247 BC053362 BU071985 BQ574185 BC064927 BG057723 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for UNK (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^
    SP1:                                                                                      -     -                                                               
    SP2:              -     -     -     -     -     -     -     -                             -     -                                                               
    SP3:                                                                                                                                                            
    SP4:                          -           -                                                                                                                     
    SP5:              -     -     -     -     -     -     -                                                                                                         

    ExUns: 16 ^ 17
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for UNK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UNK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCGGTGA
    UNK Expression
    About this image


    See UNK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UNK

    SOURCE GeneReport for Unigene clusters: Hs.584768 Hs.732048
        SABiosciences Expression via Pathway-Focused PCR Array including UNK: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNK

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for UNK gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Unk1 , 5 unkempt homolog (Drosophila)1, 5 91.48(n)1
    95.43(a)1
      11 (80.91 cM)5
    2173311  NM_172569.31  NP_766157.11 
     1160303225 
    chicken
    (Gallus gallus)
    Aves UNK1 unkempt homolog (Drosophila) 79.53(n)
    89.55(a)
      417371  XM_415628.3  XP_415628.3 
    lizard
    (Anolis carolinensis)
    Reptilia UNK6
    unkempt homolog (Drosophila)
    86(a)
    1 ↔ 1
    2(113576457-113653673)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984972 hypothetical protein LOC398497 78.35(n)    BC046725.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc554072 hypothetical protein MGC55407 77.99(n)   393205  BC047170.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta unk1 unkempt 57.33(n)
    54.21(a)
      42738  NM_176545.2  NP_788722.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C34D10.26
    Protein C34D10.2
    35(a)
    1 → many
    X(8018019-8025888)


    ENSEMBL Gene Tree for UNK (if available)
    TreeFam Gene Tree for UNK (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UNK gene
    UNKL2  
    1 SIMAP similar gene for UNK using alignment to 6 protein entries:     UNK_HUMAN (see all proteins):
    UNKL

    UNK for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/744 SNPs in UNK are shown (see all 744)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857709601,2
    --73778937(+) TGGGCA/GTGGTG 2 -- us2k10--------
    rs1910184481,2
    --73778951(+) CACACC/TTGTAA 2 -- us2k10--------
    rs780579601,2
    C--73779075(+) TGCCTT/CAAAAA 2 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs610019571,2
    C--73779076(+) AAAAA-/AAGGCTG 2 -- us2k11Minor allele frequency- AA:0.00NA 2
    rs1153571721,2
    F--73779138(+) GGTATG/ATTTCA 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs80760521,2
    C,F,A,H--73779198(+) AGAATC/AAAAAA 2 -- us2k122Minor allele frequency- A:0.36NS EA NA WA CSA 2350
    rs1125112991,2
    C,F--73779367(+) TTTTGT/AAAATT 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs80793531,2
    C,F,A--73779398(+) TCTCCC/GAACTC 2 -- us2k12Minor allele frequency- G:0.19CSA WA 119
    rs1869604381,2
    --73779546(+) TAGGAG/TTAAAG 2 -- us2k10--------
    rs1906180131,2
    --73779555(+) AGCAAC/TATACT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for UNK (73780681 - 73821886 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for UNK (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716247CNV Deletion23290073
    esv2716248CNV Deletion23290073
    esv2716249CNV Deletion23290073
    esv2743244CNV Deletion23290073
    esv2716246CNV Deletion23290073
    nsv908804CNV Loss21882294
    nsv908820CNV Loss21882294
    dgv3268n71CNV Loss21882294
    dgv3267n71CNV Loss21882294
    nsv470606CNV Loss18288195

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing UNK
    DNA2.0 Custom Variant and Variant Library Synthesis for UNK

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606532    OMIM disorders: --

    2 diseases for UNK:    About MalaCards
    eclampsia    pre-eclampsia


    UNK for disorders           About GeneDecksing


    Export disorders for UNK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UNK gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with UNK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    6. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (2009)
    7. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    10. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)1 Tao W.A.... Aebersold R. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 85451 HGNC: 29369 AceView: ZC3HDC5 Ensembl:ENSG00000132478 euGenes: HUgn85451
    ECgene: UNK H-InvDB: UNK

    (According to HUGE)
    About This Section
    HUGE: KIAA1753

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UNK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UNK gene:
    Search GeneIP for patents involving UNK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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