Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



UNK Gene

protein-coding   GIFtS: 48
GCID: GC17P073780

Unkempt Family Zinc Finger

(Previous names: zinc finger CCCH-type domain containing 5, zinc finger CCCH-type...)
(Previous symbols: ZC3HDC5, ZC3H5)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Unkempt Family Zinc Finger1 2     Unkempt Homolog (Drosophila)1
ZC3H51 2 3     RING Finger Protein Unkempt Homolog2
ZC3HDC51 2 3     Unkempt Homolog2
Zinc Finger CCCH-Type Containing 51 2     Zinc Finger CCCH Type Domain Containing 52
Zinc Finger CCCH-Type Domain Containing 51 2     KIAA17533
Zinc Finger CCCH Domain-Containing Protein 52 3     H5

External Ids:    HGNC: 293691   Entrez Gene: 854512   Ensembl: ENSG000001324787   OMIM: 6065325   UniProtKB: Q9C0B03   

Export aliases for UNK gene to outside databases

Previous GC identifers: GC17P071293 GC17P069206


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for UNK Gene:
UNK (unkempt family zinc finger) is a protein-coding gene. An important paralog of this gene is UNKL.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UNK gene promoter:
         Sox5   AML1a   AP-4   Arnt   Egr-4   Pax-3   HSF2   MRF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for UNK

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UNK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.3

UNK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UNK gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P073780:  view genomic region     (about GC identifiers)

Start:
73,780,681 bp from pter      End:
73,821,886 bp from pter
Size:
41,206 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: UNK_HUMAN, Q9C0B0 (See protein sequence)
Recommended Name: RING finger protein unkempt homolog  
Size: 810 amino acids; 88084 Da
Sequence caution: Sequence=AAH53362.1; Type=Erroneous initiation; Sequence=BAB21844.1; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for UNK: NX_Q9C0B0

Explore proteomics data for UNK at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See UNK Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001073888.2  
    ENSEMBL proteins: 
     ENSP00000464893   ENSP00000464953   ENSP00000467849   ENSP00000466431   ENSP00000466054  
     ENSP00000467726   ENSP00000293218  

    UNK Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for UNK
    OriGene Custom MassSpec
    OriGene Custom Protein Services for UNK
    GenScript Custom Purified and Recombinant Proteins Services for UNK
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UNK

     
    Search eBioscience for Proteins for UNK 

     
    Search antibodies-online for proteins for UNK 

     
    antibodies-online peptides for UNK

    UNK Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for UNK
    Novus Biologicals UNK Antibodies
    Abcam antibodies for UNK
    Cloud-Clone Corp. Antibodies for UNK
    ThermoFisher Antibodies for UNK
    LSBio Antibodies in human, mouse, rat for UNK
    antibodies-online antibodies for UNK (8 products) 

    UNK Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for UNK
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for UNK
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for UNK
    Cloud-Clone Corp. CLIAs for UNK
    Search eBioscience for ELISAs for UNK 
    antibodies-online kits for UNK (7 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZC3H: Zinc fingers, CCCH-type domain containing

    2 InterPro protein domains:
     IPR000571 Znf_CCCH
     IPR001841 Znf_RING

    Graphical View of Domain Structure for InterPro Entry Q9C0B0

    ProtoNet protein and cluster: Q9C0B0

    2 Blocks protein domains:
    IPB000571 Zn-finger
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: UNK_HUMAN, Q9C0B0
    Similarity: Belongs to the unkempt family
    Similarity: Contains 5 C3H1-type zinc fingers
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with UNK           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0044822poly(A) RNA binding IDA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with UNK           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UNK
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UNK

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UNK
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UNK

    miRNA
    Products:
        
    miRTarBase miRNAs that target UNK:
    hsa-let-7a-5p (MIRT052613), hsa-mir-186-5p (MIRT044930), hsa-mir-760 (MIRT036720), hsa-mir-17-3p (MIRT050757)

    Block miRNA regulation of human, mouse, rat UNK using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UNK (see all 61):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-517a hsa-miR-106a hsa-miR-517c hsa-miR-29a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for UNK
    Predesigned siRNA for gene silencing in human, mouse, rat UNK

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for UNK

    Clone
    Products:
         
    OriGene clones in human, mouse for UNK (see all 7)
    OriGene ORF clones in mouse, rat for UNK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNK (NM_014586)
    Sino Biological Human cDNA Clone for UNK
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNK
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNK

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for UNK
    Browse ESI BIO Cell Lines and PureStem Progenitors for UNK 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNK


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Pathway & Disease-focused RT2 Profiler PCR Array including UNK: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for UNK

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for UNK (Q9C0B02, 3 ENSP000002932184) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2877796 I2D: score=2 STRING: ENSP00000244769
    PAX8Q067103I2D: score=1 
    HECAENSP000003566304STRING: ENSP00000356630
    MAPKAP1ENSP000002659604STRING: ENSP00000265960
    MLST8ENSP000003718884STRING: ENSP00000371888
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UNK



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for UNK gene: 
    NM_001080419.2  

    Unigene Cluster for UNK:

    Unkempt homolog (Drosophila)
    Hs.584768  [show with all ESTs]
    Unigene Representative Sequence: NM_001080419
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589666 ENST00000589790 ENST00000587501 ENST00000586527 ENST00000592629
    ENST00000592074 ENST00000586217 ENST00000587258 ENST00000293218(uc002jpm.3 uc002jpn.3 uc002jpo.3 uc021udd.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat UNK using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UNK (see all 61):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-517a hsa-miR-106a hsa-miR-517c hsa-miR-29a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for UNK
    Predesigned siRNA for gene silencing in human, mouse, rat UNK
    Clone
    Products:
         
    OriGene clones in human, mouse for UNK (see all 7)
    OriGene ORF clones in mouse, rat for UNK
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNK (NM_014586)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNK
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNK
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for UNK
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UNK
      QuantiTect SYBR Green Assays in human, mouse, rat UNK
      QuantiFast Probe-based Assays in human, mouse, rat UNK

    Additional mRNA sequence: 

    AB051540.1 AL832312.1 BC038802.1 BC053362.1 

    7 DOTS entries:

    DT.308728  DT.95262902  DT.100702421  DT.100750042  DT.102842502  DT.91684837  DT.99930640 

    Selected AceView cDNA sequences (see all 141):

    BU164499 BG057723 BU181655 BQ001865 BC080657 BG169653 BU170398 BQ433050 
    AI382231 CR591163 Z41173 AB051540 BC039606 CB242820 CA438247 BC064927 
    BC038802 BM975496 BQ574185 AA886979 BC053362 BC033751 AI684809 BU943445 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for UNK (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^
    SP1:                                                                                      -     -                                                               
    SP2:              -     -     -     -     -     -     -     -                             -     -                                                               
    SP3:                                                                                                                                                            
    SP4:                          -           -                                                                                                                     
    SP5:              -     -     -     -     -     -     -                                                                                                         

    ExUns: 16 ^ 17
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for UNK

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    UNK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTCGGTGA
    UNK Expression
    About this image

    UNK Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UNK Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.584768
        Pathway & Disease-focused RT2 Profiler PCR Array including UNK: 
              Ubiquitin Ligases in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for UNK
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UNK
    QuantiTect SYBR Green Assays in human, mouse, rat UNK
    QuantiFast Probe-based Assays in human, mouse, rat UNK
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNK

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for UNK gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Unk1 , 5 unkempt homolog (Drosophila)1, 5 91.32(n)1
    95.32(a)1
      11 (80.91 cM)5
    2173311  NM_172569.41  NP_766157.11 
     1160303225 
    chicken
    (Gallus gallus)
    Aves UNK1 unkempt homolog (Drosophila) 79.21(n)
    88.99(a)
      417371  XM_415628.4  XP_415628.4 
    lizard
    (Anolis carolinensis)
    Reptilia UNK6
    unkempt family zinc finger
    86(a)
    1 ↔ 1
    2(113576457-113653673)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3984972 hypothetical protein LOC398497 78.35(n)    BC046725.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc554072 hypothetical protein MGC55407 77.99(n)   393205  BC047170.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta unk6
    unkempt
    44(a)
    1 → many
    3R(18975963-18983592)
    worm
    (Caenorhabditis elegans)
    Secernentea C34D10.26
    Protein C34D10.2, isoform b (C34D10.2) mRNA, compl...
    31(a)
    1 → many
    X(8015044-8026799) WBGene00016407


    ENSEMBL Gene Tree for UNK (if available)
    TreeFam Gene Tree for UNK (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for UNK gene
    UNKL2  
    1 SIMAP similar gene for UNK using alignment to 6 protein entries:     UNK_HUMAN (see all proteins):
    UNKL

    Find genes that share paralogs with UNK           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for UNK (see all 744)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857709601,2
    --73778937(+) TGGGCA/GTGGTG 2 -- us2k10--------
    rs1910184481,2
    --73778951(+) CACACC/TTGTAA 2 -- us2k10--------
    rs780579601,2
    C--73779075(+) TGCCTT/CAAAAA 2 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs610019571,2
    C--73779076(+) AAAAA-/AAGGCTG 2 -- us2k11Minor allele frequency- AA:0.00NA 2
    rs1153571721,2
    F--73779138(+) GGTATG/ATTTCA 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs80760521,2
    C,F,A,H--73779198(+) AGAATC/AAAAAA 2 -- us2k122Minor allele frequency- A:0.36NS EA NA WA CSA 2350
    rs1125112991,2
    C,F--73779367(+) TTTTGT/AAAATT 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs80793531,2
    C,F,A--73779398(+) TCTCCC/GAACTC 2 -- us2k12Minor allele frequency- G:0.19CSA WA 119
    rs1869604381,2
    --73779546(+) TAGGAG/TTAAAG 2 -- us2k10--------
    rs1906180131,2
    --73779555(+) AGCAAC/TATACT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for UNK (73780681 - 73821886 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for UNK (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2716247CNV Deletion23290073
    esv2716248CNV Deletion23290073
    esv2716249CNV Deletion23290073
    esv2743244CNV Deletion23290073
    esv2716246CNV Deletion23290073
    nsv908804CNV Loss21882294
    nsv908820CNV Loss21882294
    dgv3268n71CNV Loss21882294
    dgv3267n71CNV Loss21882294
    nsv470606CNV Loss18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UNK
    DNA2.0 Custom Variant and Variant Library Synthesis for UNK

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 606532    OMIM disorders: --


    Find genes that share disorders with UNK           About GenesLikeMe


    Export disorders for UNK gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for UNK gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with UNK)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    10. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (Cell 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 85451 HGNC: 29369 AceView: ZC3HDC5 Ensembl:ENSG00000132478 euGenes: HUgn85451
    ECgene: UNK H-InvDB: UNK

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1753

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for UNK Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for UNK gene:
    Search GeneIP for patents involving UNK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for UNK  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for UNK  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for UNK  
     OriGene qSTAR qPCR primer pairs in human, mouse for UNK   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for UNK   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for UNK   OriGene Custom Protein Services for UNK  

     
     
     Block miRNA regulation of human, mouse, rat UNK using miScript Target Protectors SeqTarget long-range PCR primers for resequencing UNK
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UNK Predesigned siRNA for gene silencing in human, mouse, rat UNK
     QuantiFast Probe-based Assays in human, mouse, rat UNK QuantiTect SYBR Green Assays in human, mouse, rat UNK
     PCR Arrays including human, mouse, rat UNK Search Chromatin IP Primers for UNK
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UNK  Search GeneGlobe Interaction Network for UNK
     Regulatory tfbs in UNK promoter
     GenScript Custom Purified and Recombinant Proteins Services for UNK GenScript cDNA clones with any tag delivered in your preferred vector for UNK
     GenScript Custom Assay Services for UNK GenScript Custom overexpressing Cell Line Services for UNK
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for UNK
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for UNK
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     UNK antibodies
     Antibodies for UNK
     See all of Abcam's Antibodies, Kits and Proteins for UNK
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for UNK
     Antibodies for UNK
     ELISAs for UNK
     CLIAs for UNK



     Browse ESI BIO Cell Lines and PureStem Progenitors for UNK
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNK
     Browse SwitchGear 3'UTR luciferase reporter plasmids for UNK
     Browse SwitchGear Promoter luciferase reporter plasmids for UNK
     ThermoFisher Antibodies for UNK
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNK
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UNK
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UNK
     LSBio Antibodies in human, mouse, rat for UNK
     Browse compounds at ApexBio
     Search Addgene for plasmids for UNK
      Search eBioscience for proteins for UNK
      Search eBioscience for elisas for UNK
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     antibodies-online antibodies for UNK (8 products)
     antibodies-online kits for UNK (7 products)
     antibodies-online peptides for UNK
      Search antibodies-online for proteins for UNK
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      UNK gene at Home site.
    Version: 3.12.234 23 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4