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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UNCX Gene

protein-coding   GIFtS: 37
GCID: GC07P001272

UNC Homeobox

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UNC Homeobox1 2
Homeobox Protein Uncx4.12 3
UNCX4.12 3
Homeobox Protein Unc-4 Homolog2
Unc4.1 Homeobox2

External Ids:    HGNC: 331941   Entrez Gene: 3402602   Ensembl: ENSG000001648537   UniProtKB: A6NJT03   

Export aliases for UNCX gene to outside databases

Previous GC identifers: GC07P001241 GC07P001189


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for UNCX Gene: 
UNCX (UNC homeobox) is a protein-coding gene. Diseases associated with UNCX include ventricular septal defect, and double outlet right ventricle. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is GSC.

UniProtKB/Swiss-Prot: UNC4_HUMAN, A6NJT0
Function: Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and
differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in
controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central
neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UNCX gene promoter:
         SREBP-1c   CUTL1   NF-kappaB   SREBP-1b   N-Myc   SREBP-1a   NF-kappaB2   STAT3   NF-kappaB1   MRF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for UNCX

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNCX


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

UNCX Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UNCX gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P001272:  view genomic region     (about GC identifiers)

Start:
1,272,543 bp from pter      End:
1,276,954 bp from pter
Size:
4,412 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 1,325,450-1,343,496     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UNC4_HUMAN, A6NJT0 (See protein sequence)
Recommended Name: Homeobox protein unc-4 homolog  
Size: 531 amino acids; 53690 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: A4D221

Explore the universe of human proteins at neXtProt for UNCX: NX_A6NJT0

Explore proteomics data for UNCX at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A6NJT0

  • UNCX Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    UNCX Protein Expression
    REFSEQ proteins: NP_001073930.1  
    ENSEMBL proteins: 
     ENSP00000314480  

    Human Recombinant Protein Products for UNCX: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for UNCX
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for UNCX
    GenScript Custom Purified and Recombinant Proteins Services for UNCX
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UNCX 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    UNCX for ontologies           About GeneDecksing



    UNCX Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    GenScript Custom Superior Antibodies Services for UNCX
    Novus Biologicals UNCX Antibodies
    Abcam antibodies for UNCX
    Cloud-Clone Corp. Antibodies for UNCX 
    Search ThermoFisher Antibodies for UNCX
    LSBio Antibodies in human, mouse, rat for UNCX 

    Assay Products for UNCX: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for UNCX 
    Cloud-Clone Corp. CLIAs for UNCX


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PRD: Homeoboxes / PRD class

    3 InterPro protein domains:
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry A6NJT0

    ProtoNet protein and cluster: A6NJT0

    UniProtKB/Swiss-Prot: UNC4_HUMAN, A6NJT0
    Similarity: Belongs to the paired homeobox family. Unc-4 subfamily
    Similarity: Contains 1 homeobox DNA-binding domain


    UNCX for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UNC4_HUMAN, A6NJT0
    Function: Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and
    differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in
    controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central
    neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By
    similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
         
    UNCX for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Uncx):
     growth/size  mortality/aging  nervous system  renal/urinary system  respiratory system 
     skeleton 

    UNCX for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Uncxtm1Akis for UNCX

       inGenious Targeting Laboratory - Custom generated mouse model solutions for UNCX 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for UNCX

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UNCX 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UNCX 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNCX
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate UNCX
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for UNCX
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNCX

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for UNCX
    Sirion Biotech Customized adenovirus for overexpression of UNCX

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for UNCX (see all 6)
    OriGene ORF clones in mouse, rat for UNCX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNCX (NM_001080461)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNCX
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNCX
    Sirion Biotech Customized lentivirus for stable overexpression of UNCX 
                         Customized lentivirus expression plasmids for stable overexpression of UNCX 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for UNCX
    Search LifeMap BioReagents cell lines for UNCX
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNCX


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UNCX

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001502cartilage condensation IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007389pattern specification process IEA--
    GO:0010468regulation of gene expression ----

    UNCX for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UNCX (UNC4)

    Search CenterWatch for drugs/clinical trials and news about UNCX / UNC4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for UNCX gene: 
    NM_001080461.1  

    Unigene Cluster for UNCX:

    UNC homeobox
    Hs.232272
    Unigene Representative Sequence: NM_001080461
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000316333(uc011jvw.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UNCX
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate UNCX
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for UNCX
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNCX
    Clone
    Products:
         
    OriGene clones in human, mouse for UNCX (see all 6)
    OriGene ORF clones in mouse, rat for UNCX
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UNCX (NM_001080461)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNCX
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNCX
    Sirion Biotech Customized lentivirus for stable overexpression of UNCX 
                         Customized lentivirus expression plasmids for stable overexpression of UNCX 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for UNCX
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNCX
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNCX
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNCX

    1 DOTS entry:

    DT.99931508 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UNCX expression in normal human tissues (normalized intensities)      UNCX embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACCCGGAGG
    UNCX Expression
    About this image


    UNCX expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/19 selected tissues (see all 19) fully expand
     
     Brain (Nervous System)    fully expand to see all 22 entries
             Embryonic Dopaminergic Neurons Ventral Tegmental Area
             Thalamus
             Septum   
     
     Bone (Muscoskeletal System)    fully expand to see all 12 entries
             Prechondrocytic Mesenchymal Cells Thoracic Distal Rib
             Membranous Facial Bones
             skeleton/cranium   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 11 entries
             Lumbar Sclerotome Cells Lumbar Mesenchymal Sclerotome
             skeleton/cranium   
     
     Somite (Muscoskeletal System)    fully expand to see all 10 entries
             Sacral Somite Cells Sacral Somites
             skeleton/axial skeleton   
     
     Tendon & Ligament
             Lumbar Sclerotome Cells Lumbar Mesenchymal Sclerotome

    See UNCX Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.232272
        SABiosciences Custom PCR Arrays for UNCX
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for UNCX
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNCX
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNCX
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNCX
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNCX

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for UNCX gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Uncx1 , 5 UNC homeobox1, 5 87.01(n)1
    89.83(a)1
      5 (78.75 cM)5
    222551  NM_013702.31  NP_038730.11 
     1395434945 
    chicken
    (Gallus gallus)
    Aves UNCX1 UNC homeobox 74.63(n)
    76.78(a)
      416458  XM_414766.3  XP_414766.3 
    zebrafish
    (Danio rerio)
    Actinopterygii uncx4.11 Unc4.1 homeobox (C. elegans) 64.22(n)
    69.21(a)
      553947  NM_001020780.2  NP_001018616.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta repo6
    unc-46
    (see all 5)
    unc-4
    (see all 5)
    9(a)
    25(a)
    (see all 5)
    possible ortholog
    1 ↔ many
    (see all 5)
    3R(14061916-14065324)
    X(17663416-17674916)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-46
    Homeobox protein unc-4
    28(a)
    1 ↔ 1
    II(9897754-9900257)


    ENSEMBL Gene Tree for UNCX (if available)
    TreeFam Gene Tree for UNCX (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UNCX gene
    GSC2  PITX12  OTX22  VSX12  HESX12  RHOXF22  PITX22  VSX22  
    RHOXF12  PITX32  DMBX12  ESX12  GSC22  OTX12  RHOXF2B2  CRX2  
    2 SIMAP similar genes for UNCX using alignment to 1 protein entry:     UNC4_HUMAN:
    NKX6-1    RAX2

    UNCX for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/107 SNPs in UNCX are shown (see all 107)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69503881,2
    C,F--1270699(+) ATAGAG/AACAGA 1 -- us2k19Minor allele frequency- A:0.44NA WA EA 370
    rs580639231,2
    C--1270738(+) TTGGCC/TTCTGA 1 -- us2k13Minor allele frequency- T:0.21NA EA 242
    rs1142125501,2
    F--1270810(+) AAATTC/TCAGGC 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1122650651,2
    F--1271096(+) CTGACC/TCGGAG 1 -- us2k12Minor allele frequency- T:0.02CSA WA 120
    rs1412241191,2
    --1271133(+) CCTGCC/TCTTCC 1 -- us2k10--------
    rs1901331961,2
    --1271145(+) TCTCAA/CGCGGG 1 -- us2k10--------
    rs69511991,2
    C--1271148(+) CACGCA/GGGCTA 1 -- us2k10--------
    rs107087571,2
    C--1271234(+) GTGGCT/-CCGCA 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs797989171,2
    F--1271399(+) TTTACA/GAAGGA 1 -- us2k10--------
    rs766621171,2
    --1271423(+) ACATCA/CCCTCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for UNCX (1272543 - 1276954 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/20 variations for UNCX (see all 20):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2673144CNV Deletion23128226
    nsv830876CNV Loss17160897
    esv23542CNV Loss19812545
    nsv830877CNV Loss17160897
    nsv887172CNV Loss21882294
    nsv887128CNV Loss21882294
    nsv887166CNV Loss21882294
    dgv7074n71CNV Loss21882294
    dgv7087n71CNV Loss21882294
    nsv887164CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing UNCX
    DNA2.0 Custom Variant and Variant Library Synthesis for UNCX

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for UNCX:    About MalaCards
    ventricular septal defect    double outlet right ventricle    spina bifida    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for UNCX:
    Ventricular septal defect     Spina bifida

    UNCX for disorders           About GeneDecksing


    Export disorders for UNCX gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UNCX gene integrated from 9 sources:
    (articles sorted by number of sources associating them with UNCX)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    2. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    3. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. (PubMed id 22797727)1 Okada Y....Tanaka T. (2012)
    4. Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV- infected men. (PubMed id 21897333)1 Irvin M.R....Arnett D.K. (2011)
    5. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 340260 HGNC: 33194 Ensembl:ENSG00000164853 euGenes: HUgn340260 ECgene: UNCX
    H-InvDB: UNCX

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UNCX Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UNCX gene:
    Search GeneIP for patents involving UNCX

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Regulatory tfbs in UNCX promoter
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     Proteins for UNCX
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     Search ThermoFisher Antibodies for UNCX
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat UNCX
     inGenious Targeting Laboratory - Custom generated mouse model solutions for UNCX
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


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