UNC93B1 Gene
protein-coding GIFtS: 55
GCID: GC11M067759
|
|
unc-93 homolog B1 (C. elegans)(Previous name: unc93 (C. elegans) homolog B1 )
| |
Aliases
for UNC93B1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Unc-93 Homolog B1 (C. Elegans)1 2 | | IIAE12 | | UNC931 2 3 | | Protein Unc-93 Homolog B12 | | UNC93B2 3 | | Unc-93 Related Protein2 | | Unc-93B12 3 | | Unc93 Homolog B2 | | HUNC93B11 | | Unc93 Homolog B12 | | Unc93 (C. Elegans) Homolog B11 | | |
Export aliases for UNC93B1 gene to outside databasesPrevious GC identifers: GC11M070281 GC11M069454 GC11M068008 GC11M067533 GC11M067515 GC11M064093 |
Summaries
for UNC93B1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UNC93B1:
This gene encodes a protein with similarity to the C. elegans unc93 protein. The Unc93 protein is involved in theregulation or coordination of muscle contraction in the worm. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4Function: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor(TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmicreticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a rolein autoreactive B-cells removal
Gene Wiki entry for UNC93B1
|
Genomic Views
for UNC93B1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UNC93B1 gene promoter:
AML1a Pax-5 MIF-1 E47 Egr-2 POU2F1 HOXA5 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for UNC93B1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNC93B1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.2UNC93B1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M067759: view genomic region
(about GC identifiers)
Start:
|
67,758,575 bp from pter |
End:
|
67,772,452 bp from pter |
Size:
|
13,878 bases |
Orientation:
|
minus strand |
|
Proteins
for UNC93B1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4 (See
protein sequence)Recommended Name: Protein unc-93 homolog B1 Size: 597 amino acids; 66631 Da
Subunit: Interacts with TLR3, TLR7, and TLR9 (probably via transmembrane domain) (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Endosome (Bysimilarity). Lysosome (By similarity). Cytoplasmic vesicle, phagosome (By similarity). Note=Relocalizes fromendoplasmic reticulum to endosome and lysosome upon cell-stimulation with CpG dinucleotides (By similarity).Colocalizes with LAMP5 in large endosomal intracellular vesicles
Sequence caution: Sequence=AAD15416.1; Type=Erroneous gene model prediction;
Secondary accessions: O95764 Q569H6 Q710D4Explore the universe of human proteins at neXtProt for UNC93B1: NX_Q9H1C4
Post-translational modifications:
N-glycosylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H1C4
UNC93B1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112192.2
ENSEMBL proteins: ENSP00000434294 ENSP00000437195 ENSP00000436758 ENSP00000227471 Reactome Protein details: Q9H1C4
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
UNC93B1 for ontologies About GeneDecksing
UNC93B1 Antibody Products:
Assay Products for UNC93B1: |
Protein
Domains /
Families
for UNC93B1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UNC93B1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H1C4ProtoNet protein and cluster: Q9H1C4 UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4Similarity: Belongs to the unc-93 family |
Function
for UNC93B1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4Function: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor(TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmicreticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a rolein autoreactive B-cells removalInduction: Up-regulated by TLRs agonists
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC93B1 |
1 GenomeRNAi human phenotype for UNC93B1:
Animal Models:
8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Unc93b1):
UNC93B1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for UNC93B1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Endosomal TLRs pass through the Golgi | | | 2 | Immune System | | | 3 | TRAF6 Mediated Induction of proinflammatory cytokines | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/6 
Reactome Pathways for UNC93B1 (see all 6)
UNC93B1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UNC93B1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/32 Interacting proteins for UNC93B1 (Q9H1C43 ENSP000002274714) via UniProtKB, MINT, STRING, and/or I2D (see all 32)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
UNC93B1 for ontologies About GeneDecksing
|
Drugs & Compounds
for UNC93B1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UNC93B1
Search CenterWatch for drugs/clinical trials and news about UNC93B1 / UN93B
|
Transcripts
for UNC93B1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UNC93B1 gene: NM_030930.2 Unigene Cluster for UNC93B1: Unc-93 homolog B1 (C. elegans) Hs.502989 [show with all ESTs]Unigene Representative Sequence: NM_03093011 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000533966 ENST00000530331 ENST00000525368 ENST00000525743 ENST00000533424
ENST00000524455 ENST00000528423 ENST00000528096 ENST00000530138 ENST00000531152
ENST00000227471(uc001omw.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UNC93B1 (NM_030930) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UNC93B1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UNC93B1 |
Additional cDNA sequence: AJ271326.1 AJ422142.1 AY007125.1 BC025669.1 BC033623.1 BC092472.1 BC101568.1 BC105104.1 12 DOTS entries: DT.100839527 DT.95291731 DT.97854662 DT.95364316 DT.200613 DT.100822082 DT.91805027 DT.112377 DT.120727139 DT.121047962 DT.121235726 DT.95116171 24/341 AceView cDNA sequences (see all 341): BM763809 BM756569 CD364855 BM741763 BQ957710 BM973063 BQ072767 BI905908 AI972019 BM767843 BM738095 BM764391 BM768202 AI378246 BM563622 CA308331 BI916186 BQ073179 BM717491 AI278852 AW295691 BE501187 BM755928 NM_030930
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UNC93B1 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UNC93B1
|
Expression
for UNC93B1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UNC93B1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGACGGCGC
About this image
See UNC93B1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UNC93B1
SOURCE GeneReport for Unigene cluster: Hs.502989
UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4Tissue specificity: Expressed in plasmocytoid dendritic cells (at protein level). Highly expressed inantigen-presenting cells. Expressed in heart, and at lower level in kidney. Expressed at low level in other tissues
SABiosciences Custom PCR Arrays for UNC93B1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UNC93B1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNC93B1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNC93B1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNC93B1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC93B1 |
Orthologs
for UNC93B1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UNC93B1 gene from 6/15 species (see all 15) About this table
ENSEMBL Gene Tree for UNC93B1 (if available)
TreeFam Gene Tree for UNC93B1 (if available) |
Paralogs
for UNC93B1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UNC93B1 gene
- ENSG000002330942 UNC93A2
1 SIMAP similar gene for UNC93B1 using alignment to 6 protein entries: UN93B_HUMAN (see all proteins):UNC93A
UNC93B1 for paralogs About GeneDecksing
|
Genomic Variants
for UNC93B1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UNC93B1 (67758575 - 67772452 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for UNC93B1
7 CNVs: 85827 2931 29914 3856 53160 30558 29913
Human Gene Mutation Database (HGMD): UNC93B1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UNC93B1 |
|
Disorders
/ Diseases
for UNC93B1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UNC93B1 for disorders About GeneDecksing
OMIM gene information: 608204
OMIM disorders: 610551
UniProtKB/Swiss-Prot: UN93B_HUMAN, Q9H1C4
Defects in UNC93B1 are associated with herpes simplex encephalitis type 1 (HSE1) [MIM:610551]. HSE is a rarecomplication of human herpesvirus 1 (HHV-1) infection, occurring in only a small minority of HHV-1 infectedindividuals. HSE is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is overseveral days and involves fever, headache, seizures, stupor, and often coma, frequently with a fatal outcome.Note=Mutations in UNC93B1 resulting in autosomal recessive UNC93B1 deficieny predispose otherwise healthy individualsto isolated herpes simplex encephalitis due to impaired IFNs production. UNC93B1 deficieny, however, does notcompromise immunity to most pathogens, unlike most known primary immunodeficiencies
5  diseases for UNC93B1: About MalaCardsmelkersson-rosenthal syndrome herpes simplex encephalitis herpes simplex encephalitis
headache
3 diseases from the University of Copenhagen DISEASES database for UNC93B1:Encephalitis Herpes simplex Melkersson-Rosenthal syndrome Export disorders for UNC93B1 gene to outside databases
|
Publications
for UNC93B1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UNC93B1 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with UNC93B1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein. (PubMed id 11867227)1, 2, 3, 9 Kashuba V.I.... Zabarovsky E.R. (2002)
- Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response. (PubMed id 18082565)1, 2, 9 Koehn J....Korthauer U. (2007)
- IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. (PubMed id 19006693)1, 2 Isnardi I....Meffre E. (2008)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)1, 2 Taylor T.D....Sakaki Y. (2006)
- Herpes simplex virus encephalitis in human UNC-93B deficiency. (PubMed id 16973841)1, 2 Casrouge A....Casanova J.-L. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling. (PubMed id 22611194)1 Garcia-Cattaneo A....Benaroch P. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- UNC93B1 physically associates with human TLR8 and regu lates TLR8-mediated signaling. (PubMed id 22164301)1 Itoh H....Matsumoto M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for UNC93B1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UNC93B1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UNC93B1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UNC93B1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UNC93B1 | Pharmacogenomics, SNPs, Pathways | | UNC93B1base | http://bioinf.uta.fi/UNC93B1base/ |
|
| | |
About This Section
| Patent Information for UNC93B1 gene:
Search GeneIP for patents involving UNC93B1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UNC93B1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for UNC93B1 | | OriGene shRNA RFP for UNC93B1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UNC93B1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UNC93B1 | | | OriGene Protein Over-expression Lysate for UNC93B1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UNC93B1 | | OriGene 3'-UTR Clone for UNC93B1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UNC93B1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UNC93B1 | | OriGene Custom Protein Services for UNC93B1 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UNC93B1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UNC93B1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNC93B1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNC93B1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNC93B1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNC93B1 |
| |
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 | | | UNC93B1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC93B1 |
|  |  |  | | | | ThermoFisher Antibodies for UNC93B1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UNC93B1 |
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