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Aliases for UNC93A Gene

Aliases for UNC93A Gene

  • Unc-93 Homolog A (C. Elegans) 2 3 5
  • Unc-93A 3 4
  • DJ366N23.2 (Putative C. Elegans UNC-93 (Protein 1, C46F11.1) C-Terminal LIKE) 3
  • DJ366N23.1 (Putative C. Elegans UNC-93 (Protein 1, C46F11.1) LIKE) 3
  • Unc93 (C.Elegans) Homolog A 2
  • Unc93 Homolog A 3
  • DJ366N23.1 3
  • DJ366N23.2 3
  • HmUnc-93A 4

External Ids for UNC93A Gene

Previous GeneCards Identifiers for UNC93A Gene

  • GC06P167058
  • GC06P167578
  • GC06P167614
  • GC06P167675
  • GC06P167624
  • GC06P167704
  • GC06P165177

Summaries for UNC93A Gene

GeneCards Summary for UNC93A Gene

UNC93A (Unc-93 Homolog A (C. Elegans)) is a Protein Coding gene. An important paralog of this gene is UNC93B1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UNC93A Gene

Genomics for UNC93A Gene

Regulatory Elements for UNC93A Gene

Enhancers for UNC93A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around UNC93A on UCSC Golden Path with GeneCards custom track

Genomic Location for UNC93A Gene

167,271,169 bp from pter
167,316,029 bp from pter
44,861 bases
Plus strand

Genomic View for UNC93A Gene

Genes around UNC93A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UNC93A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UNC93A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UNC93A Gene

Proteins for UNC93A Gene

  • Protein details for UNC93A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein unc-93 homolog A
    Protein Accession:
    Secondary Accessions:
    • B3KRP5
    • Q4QQJ4
    • Q5JZD6

    Protein attributes for UNC93A Gene

    457 amino acids
    Molecular mass:
    50270 Da
    Quaternary structure:
    No Data Available
    • Although UNC93A gene is located in a region of the genome frequently associated with ovarian cancer, no evidence have been found for a tumor suppressor function.
    • Sequence=CAI42706.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for UNC93A Gene


neXtProt entry for UNC93A Gene

Proteomics data for UNC93A Gene at MOPED

Post-translational modifications for UNC93A Gene

Other Protein References for UNC93A Gene

No data available for DME Specific Peptides for UNC93A Gene

Domains & Families for UNC93A Gene

Protein Domains for UNC93A Gene


Suggested Antigen Peptide Sequences for UNC93A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the unc-93 family.
  • Belongs to the unc-93 family.
genes like me logo Genes that share domains with UNC93A: view

No data available for Gene Families for UNC93A Gene

Function for UNC93A Gene

genes like me logo Genes that share phenotypes with UNC93A: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UNC93A Gene

Localization for UNC93A Gene

Subcellular locations from UniProtKB/Swiss-Prot for UNC93A Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for UNC93A Gene COMPARTMENTS Subcellular localization image for UNC93A gene
Compartment Confidence
plasma membrane 5
endosome 1

Gene Ontology (GO) - Cellular Components for UNC93A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA 12381271
genes like me logo Genes that share ontologies with UNC93A: view

Pathways & Interactions for UNC93A Gene

SuperPathways for UNC93A Gene

No Data Available

Interacting Proteins for UNC93A Gene

Selected Interacting proteins: Q86WB7-UN93A_HUMAN for UNC93A Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for UNC93A Gene


No data available for Pathways by source and SIGNOR curated interactions for UNC93A Gene

Drugs & Compounds for UNC93A Gene

No Compound Related Data Available

Transcripts for UNC93A Gene

Unigene Clusters for UNC93A Gene

Unc-93 homolog A (C. elegans):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UNC93A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5

Relevant External Links for UNC93A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for UNC93A Gene

mRNA expression in normal human tissues for UNC93A Gene

mRNA differential expression in normal tissues according to GTEx for UNC93A Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x20.8), Skin - Not Sun Exposed (Suprapubic) (x14.4), and Liver (x9.6).

Protein differential expression in normal tissues from HIPED for UNC93A Gene

This gene is overexpressed in Fetal Liver (48.6) and Urine (20.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for UNC93A Gene

SOURCE GeneReport for Unigene cluster for UNC93A Gene Hs.567508

mRNA Expression by UniProt/SwissProt for UNC93A Gene

Tissue specificity: Expressed in testis, small intestine, spleen, prostate and ovary.
genes like me logo Genes that share expression patterns with UNC93A: view

Protein tissue co-expression partners for UNC93A Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for UNC93A Gene

Orthologs for UNC93A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UNC93A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia UNC93A 35
  • 78.34 (n)
  • 74.4 (a)
UNC93A 36
  • 63 (a)
(Canis familiaris)
Mammalia UNC93A 35
  • 82.09 (n)
  • 80.7 (a)
UNC93A 36
  • 81 (a)
(Mus musculus)
Mammalia Gm9992 35
  • 76.24 (n)
  • 72.59 (a)
Unc93a 16
Gm8597 36
  • 46 (a)
Gm9992 36
  • 71 (a)
Unc93a 36
  • 72 (a)
(Pan troglodytes)
Mammalia UNC93A 35
  • 98.91 (n)
  • 98.69 (a)
UNC93A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Unc93a 35
  • 75.26 (n)
  • 72.47 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 65 (a)
-- 36
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia UNC93A 36
  • 67 (a)
(Gallus gallus)
Aves UNC93A 36
  • 64 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
-- 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487981 35
  • 61.1 (n)
  • 59.95 (a)
Str.13374 35
(Danio rerio)
Actinopterygii unc93a 35
  • 62.2 (n)
  • 58.9 (a)
unc93a 36
  • 53 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000834 35
  • 52.23 (n)
  • 41.54 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4928 35
  • 52.74 (n)
  • 41.56 (a)
CG2121 36
  • 26 (a)
CG4928 36
  • 34 (a)
(Caenorhabditis elegans)
Secernentea unc-93 35
  • 45.96 (n)
  • 34.41 (a)
unc-93 36
  • 20 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G09470 35
  • 44.47 (n)
  • 31.58 (a)
(Oryza sativa)
Liliopsida Os12g0566900 35
  • 45.12 (n)
  • 32.07 (a)
Species with no ortholog for UNC93A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UNC93A Gene

Gene Tree for UNC93A (if available)
Gene Tree for UNC93A (if available)

Paralogs for UNC93A Gene

Paralogs for UNC93A Gene

(1) SIMAP similar genes for UNC93A Gene using alignment to 2 proteins: Pseudogenes for UNC93A Gene

genes like me logo Genes that share paralogs with UNC93A: view

Variants for UNC93A Gene

Sequence variations from dbSNP and Humsavar for UNC93A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs2072767 - 167,305,948(+) AGTTC(A/G)TCGGC intron-variant, reference, missense
rs663227 - 167,315,237(+) CCAAT(C/T)ACCGC reference, missense
rs663606 - 167,315,286(+) CAGCA(C/T)GTTTT reference, missense
rs7739897 - 167,315,303(+) TGCAC(A/G)TCAAG reference, missense
VAR_022654 -

Structural Variations from Database of Genomic Variants (DGV) for UNC93A Gene

Variant ID Type Subtype PubMed ID
essv22845 CNV CNV 17122850
dgv2033e1 CNV Complex 17122850
nsv464141 CNV Gain 19166990
nsv470873 CNV Gain 18288195
nsv7389 OTHER Inversion 18451855
nsv886944 CNV Gain 21882294
esv24545 CNV Gain+Loss 19812545
dgv1081e201 CNV Deletion 23290073
esv34252 CNV Gain 17911159
nsv509170 CNV Insertion 20534489
nsv886945 CNV Loss 21882294
nsv886946 CNV Loss 21882294
esv2733230 CNV Deletion 23290073
nsv517210 CNV Gain+Loss 19592680
nsv886947 CNV Gain 21882294
esv2733231 CNV Deletion 23290073
nsv464145 CNV Loss 19166990

Variation tolerance for UNC93A Gene

Residual Variation Intolerance Score: 89.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.52; 94.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for UNC93A Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UNC93A Gene

Disorders for UNC93A Gene

Relevant External Links for UNC93A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for UNC93A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UNC93A Gene

Publications for UNC93A Gene

  1. The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. (PMID: 12381271) Liu Y. … Ganesan T.S. (BMC Genet. 2002) 2 3 4 23 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for UNC93A Gene

Sources for UNC93A Gene