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UNC45B Gene

protein-coding   GIFtS: 51
GCID: GC17P033474

Unc-45 Homolog B (C. Elegans)

(Previous name: cardiomyopathy associated 4)
(Previous symbol: CMYA4)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Unc-45 Homolog B (C. Elegans)1 2     UNC-45B2
CMYA41 2 3     Protein Unc-45 Homolog B2
Cardiomyopathy Associated 41 2     Striated Muscle UNC452
SMUNC452 3     Unc-45B3
UNC452 3     

External Ids:    HGNC: 143041   Entrez Gene: 1468622   Ensembl: ENSG000001411617   OMIM: 6112205   UniProtKB: Q8IWX73   

Export aliases for UNC45B gene to outside databases

Previous GC identifers: GC17P030500 GC17P029659


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for UNC45B Gene:
UNC45B plays a role in myoblast fusion and sarcomere organization (Price et al., 2002 (PubMed 12356907)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for UNC45B Gene:
UNC45B (unc-45 homolog B (C. elegans)) is a protein-coding gene. Diseases associated with UNC45B include breast and colorectal cancer, and multiple myeloma. GO annotations related to this gene include Hsp90 protein binding. An important paralog of this gene is TOMM70A.

UniProtKB/Swiss-Prot: UN45B_HUMAN, Q8IWX7
Function: Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a
role in sarcomere formation during muscle cell development (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UNC45B gene promoter:
         CREB   SREBP-1a   p53   SREBP-1c   deltaCREB   Nkx2-5   SREBP-1b   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUNC45B promoter sequence
   Search Chromatin IP Primers for UNC45B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UNC45B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

UNC45B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UNC45B gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P033474:  view genomic region     (about GC identifiers)

Start:
33,474,836 bp from pter      End:
33,516,364 bp from pter
Size:
41,529 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: UN45B_HUMAN, Q8IWX7 (See protein sequence)
Recommended Name: Protein unc-45 homolog B  
Size: 931 amino acids; 103733 Da
Subunit: Interacts with HSP90 in an ATP-independent manner (By similarity)
Secondary accessions: Q495Q8 Q495Q9
Alternative splicing: 3 isoforms:  Q8IWX7-1   Q8IWX7-2   Q8IWX7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UNC45B: NX_Q8IWX7

Explore proteomics data for UNC45B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See UNC45B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001028748.1  NP_001253981.1  NP_775259.1  

    ENSEMBL proteins: 
     ENSP00000268876   ENSP00000378071   ENSP00000468335   ENSP00000412840   ENSP00000367710  

    UNC45B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for UNC45B

    UNC45B Antibody Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 7):
     IPR011990 TPR-like_helical
     IPR011989 ARM-like
     IPR024660 UNC-45/Ring3
     IPR001440 TPR_1
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q8IWX7

    ProtoNet protein and cluster: Q8IWX7

    1 Blocks protein domain: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: UN45B_HUMAN, Q8IWX7
    Similarity: Contains 3 ARM repeats
    Similarity: Contains 3 TPR repeats


    UNC45B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UN45B_HUMAN, Q8IWX7
    Function: Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a
    role in sarcomere formation during muscle cell development (By similarity)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0051879Hsp90 protein binding IEA--
         
    UNC45B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for UNC45B:
     Increased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UNC45B
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    miRNA
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    miRTarBase miRNAs that target UNC45B:
    hsa-mir-324-3p (MIRT042862)

    Block miRNA regulation of human, mouse, rat UNC45B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UNC45B (see all 15):
    hsa-miR-362-3p hsa-miR-1236 hsa-miR-4306 hsa-miR-944 hsa-miR-3133 hsa-miR-3647-3p hsa-miR-3672 hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidUNC45B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat UNC45B

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC45B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UN45B_HUMAN, Q8IWX7: Cytoplasm, cytosol (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol IEA--

    UNC45B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UNC45B
    Interactions:

        Search GeneGlobe Interaction Network for UNC45B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for UNC45B (Q8IWX73 ENSP000002688764) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PEX19P408553I2D: score=4 
    MYO1EENSP000002882354STRING: ENSP00000288235
    MYO1FENSP000003448714STRING: ENSP00000344871
    ACTR2ENSP000003672204STRING: ENSP00000367220
    MYH10ENSP000002692434STRING: ENSP00000269243
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007517muscle organ development IEA--
    GO:0030154cell differentiation IEA--
    GO:0061077chaperone-mediated protein folding IEA--

    UNC45B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UNC45B (UN45B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UNC45B gene (3 alternative transcripts): 
    NM_001033576.1  NM_001267052.1  NM_173167.2  

    Unigene Cluster for UNC45B:

    Unc-45 homolog B (C. elegans)
    Hs.379636  [show with all ESTs]
    Unigene Representative Sequence: NM_173167
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000268876 ENST00000394570(uc002hja.3 uc002hjb.3 uc002hjc.3 uc010cto.3)
    ENST00000591048 ENST00000433649 ENST00000378449
    miRNA
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    Block miRNA regulation of human, mouse, rat UNC45B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UNC45B (see all 15):
    hsa-miR-362-3p hsa-miR-1236 hsa-miR-4306 hsa-miR-944 hsa-miR-3133 hsa-miR-3647-3p hsa-miR-3672 hsa-miR-329
    SwitchGear 3'UTR luciferase reporter plasmidUNC45B 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): UNC45B (NM_001033576)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UNC45B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UNC45B
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UNC45B
      QuantiTect SYBR Green Assays in human, mouse, rat UNC45B
      QuantiFast Probe-based Assays in human, mouse, rat UNC45B

    Additional mRNA sequence: 

    AF539794.1 AK095929.1 AL832355.1 AL833281.1 BC101062.2 BC101063.2 BX647642.1 

    2 DOTS entries:

    DT.436822  DT.100018844 

    Selected AceView cDNA sequences (see all 26):

    NM_173167 BM697527 AI014875 AK095929 AF539794 AA404417 AI572463 AI800785 
    BX647642 BF790722 BU735725 F16124 AL832355 AL833281 AA452197 AI246442 
    AA249623 AW755253 AI472849 AA780204 AA216015 AA780099 AJ708042 AA211338 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for UNC45B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b
    SP1:                                                                                                                                    
    SP2:                                                                                                                                    
    SP3:                                                                                                                                    


    ECgene alternative splicing isoforms for UNC45B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UNC45B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAGGCCTTT
    UNC45B Expression
    About this image


    UNC45B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 7
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Skeletal Muscle (Muscoskeletal System)
    UNC45B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UNC45B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.379636
        Custom PCR Arrays for UNC45B
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for UNC45B gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Unc45b1 , 5 unc-45 homolog B (C. elegans)1, 5 88.77(n)1
    95.05(a)1
      11 (50.30 cM)5
    2170121  NM_178680.41  NP_848795.31 
     829105505 
    chicken
    (Gallus gallus)
    Aves UNC45B1 unc-45 homolog B (C. elegans) 75.82(n)
    82.05(a)
      417527  XM_004946512.1  XP_004946569.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    79(a)
    many ↔ many
    AAWZ02040345(454-7035)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.112792 Transcribed sequence with weak similarity to protein more 75.4(n)    CF783972.1 
    zebrafish
    (Danio rerio)
    Actinopterygii unc45r2 unc-45 (C. elegans) related 76.04(n)   266640  AF330001.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta unc-451 unc-45 49.16(n)
    35.6(a)
      44910  NM_080057.3  NP_524796.1 
    worm
    (Caenorhabditis elegans)
    Secernentea unc-451 unc-45 45.03(n)
    33.22(a)
      175206  NM_064804.5  NP_497205.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TOM706
    TOM716
    Component of the TOM (translocase of outer membran...
    Mitochondrial outer membrane protein with similari...
    14(a)
    13(a)
    many ↔ many
    many ↔ many
    XIV(398684-400537) YNL121C
    VIII(342349-344268) YHR117W


    ENSEMBL Gene Tree for UNC45B (if available)
    TreeFam Gene Tree for UNC45B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UNC45B gene
    TOMM70A2  TTC12  TOMM342  SPAG12  UNC45A2  
    1 SIMAP similar gene for UNC45B using alignment to 2 protein entries:     UN45B_HUMAN (see all proteins):
    UNC45A

    UNC45B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UNC45B (see all 1087)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358704
    A breast cancer sample4--see VAR_0358702 D H mis40--------
    rs1412139941,2
    --33472842(+) CATAGA/TCACAA 3 -- us2k10--------
    rs1507084151,2
    C--33472911(+) AGAAAC/TGTGGG 3 -- us2k10--------
    rs1145814471,2
    F--33472917(+) GTGGGC/TCAGGC 3 -- us2k11Minor allele frequency- T:0.07WA 118
    rs1379084491,2
    C--33472925(+) GGCGCA/GGTGGC 3 -- us2k10--------
    rs1494702971,2
    --33473086(+) GCTACC/TCATGA 3 -- us2k10--------
    rs1472145301,2
    --33473089(+) ACTCAC/TGAGGC 3 -- us2k10--------
    rs1850814551,2
    --33473110(+) GAATCG/TCTTGA 3 -- us2k10--------
    rs1150340481,2
    C,F--33473221(+) CAAAAA/GGATGT 3 -- us2k11Minor allele frequency- G:0.03WA 118
    rs753254141,2
    C,F--33473318(+) GCCAAT/CGTCAG 3 -- us2k11Minor allele frequency- C:0.04WA 118

    HapMap Linkage Disequilibrium report for UNC45B (33474836 - 33516364 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for UNC45B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv2037CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UNC45B
    DNA2.0 Custom Variant and Variant Library Synthesis for UNC45B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611220    OMIM disorders: --

    5 diseases for UNC45B:    
    About MalaCards
    breast and colorectal cancer    multiple myeloma    myeloma    colorectal cancer
    malaria


    UNC45B for disorders           About GeneDecksing

    Genetic Association Database (GAD): UNC45B
    Human Genome Epidemiology (HuGE) Navigator: UNC45B (1 document)

    Export disorders for UNC45B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UNC45B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with UNC45B)
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    1. Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions. (PubMed id 12356907)1, 2, 3 Price M.G.... Epstein H.F. (J. Cell Sci. 2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PubMed id 22751105)1 Chu L....Tomasson M.H. (J. Clin. Invest. 2012)
    5. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 146862 HGNC: 14304 AceView: CMYA4 Ensembl:ENSG00000141161 euGenes: HUgn146862
    ECgene: UNC45B H-InvDB: UNC45B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UNC45B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UNC45B gene:
    Search GeneIP for patents involving UNC45B

    GeneCards and IP:
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