UNC13D Gene
protein-coding GIFtS: 61
GCID: GC17M073823
|
|
Unc-13 Homolog D (C. Elegans)
| |
Aliases
for UNC13D gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| Unc-13 Homolog D (C. Elegans)1 2 | | HPLH32 5 | | Munc13-42 3 | | Protein Unc-13 Homolog D2 | | FHL32 5 | | MUNC13-45 | | HLH32 5 | | |
Export aliases for UNC13D gene to outside databasesPrevious GC identifers: GC17M074420 GC17M071334 GC17M069249 |
Summaries
for UNC13D gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UNC13D Gene:
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other
family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The
protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic
granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type
3, a genetically heterogeneous, rare autosomal recessive disorder. (provided by RefSeq, Jul 2008)
GeneCards Summary for UNC13D Gene: 
UNC13D (unc-13 homolog D (C. elegans)) is a protein-coding gene. Diseases associated with UNC13D include hemophagocytic lymphohistiocytosis, and hemophagocytic lymphohistiocytosis, familial. GO annotations related to this gene include protein binding. An important paralog of this gene is BAIAP3.
UniProtKB/Swiss-Prot: UN13D_HUMAN, Q70J99Function: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and
granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal
structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing
granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory
lysosome exocytosis in mast cells
Gene Wiki entry for UNC13D Gene
|
Genomic Views
for UNC13D gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NT_010783.15 NC_018928.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UNC13D gene promoter:
E2F-4 E2F-3a GR E2F-5 p300 GR-beta E2F-2 E2F E2F-1 GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for UNC13D
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNC13D |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.3UNC13D Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M073823: view genomic region
(about GC identifiers)
Start:
|
73,823,306 bp from pter |
End:
|
73,840,798 bp from pter |
Size:
|
17,493 bases |
Orientation:
|
minus strand |
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Proteins
for UNC13D gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: UN13D_HUMAN, Q70J99 (See
protein sequence)Recommended Name: Protein unc-13 homolog D Size: 1090 amino acids; 123282 Da
Subunit: Interacts with DOC2A (By similarity). Interacts with RAB27A
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein. Late endosome. Recycling endosome.
Lysosome. Note=Colocalizes with cytotoxic granules at the plasma membrane. Localizes to endosomal exocytic
vesicles
Sequence caution: Sequence=BAB15764.1; Type=Erroneous initiation;
Secondary accessions: B4DWG9 Q9H7K5Alternative splicing: 3 isoforms: Q70J99-1 Q70J99-2 Q70J99-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UNC13D: NX_Q70J99
Explore proteomics data for UNC13D at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q70J99
UNC13D Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_954712.1
ENSEMBL proteins: ENSP00000466758 ENSP00000207549 ENSP00000388093 ENSP00000466149 ENSP00000466543 ENSP00000466377 ENSP00000466826 ENSP00000467653 ENSP00000464749
Human Recombinant Protein Products for UNC13D:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
UNC13D for ontologies About GeneDecksing
UNC13D Antibody Products:
Assay Products for UNC13D: |
Protein
Domains /
Families
for UNC13D gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| 5/6 InterPro protein domains (see all 6):Graphical View of Domain Structure for InterPro Entry Q70J99 ProtoNet protein and cluster: Q70J99 2 Blocks protein domains: IPB000008 C2 domain IPB010439 Protein of unknown function DUF1041
UniProtKB/Swiss-Prot: UN13D_HUMAN, Q70J99Domain: The MHD1 and MHD2 domains mediate localization on recycling endosomes and lysosomeSimilarity: Belongs to the unc-13 familySimilarity: Contains 2 C2 domainsSimilarity: Contains 1 MHD1 (MUNC13 homology domain 1) domainSimilarity: Contains 1 MHD2 (MUNC13 homology domain 2) domain
UNC13D for domains About GeneDecksing
|
Function
for UNC13D gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UN13D_HUMAN, Q70J99Function: Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and
granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal
structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing
granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory
lysosome exocytosis in mast cells Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
UNC13D for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for UNC13D:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Unc13d):
UNC13D for phenotypes About GeneDecksing
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for UNC13D | |  | Search LifeMap BioReagents cell lines for UNC13D | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC13D |
Pathways & Interactions
for UNC13D gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
|
SuperPaths for UNC13D About See pathways by source
| SuperPath | Contained pathways About |
|---|
| 1 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | | | 2 | wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) | |
Pathways by source See SuperPaths
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for UNC13D
1  BioSystems Pathway for UNC13D
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UNC13D
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5 Interacting proteins for UNC13D (Q70J993 ENSP000002075494) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
UNC13D for ontologies About GeneDecksing
|
Drugs & Compounds
for UNC13D gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UNC13D (UN13D)
Search CenterWatch for drugs/clinical trials and news about UNC13D / UN13D
|
Transcripts
for UNC13D gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UNC13D gene: NM_199242.2 Unigene Cluster for UNC13D: Unc-13 homolog D (C. elegans) Hs.41045 [show with all ESTs]Unigene Representative Sequence: NM_19924217 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000589670 ENST00000207549(uc002jpp.3) ENST00000412096(uc010wsk.1 uc002jpq.1 uc010dgq.1)
ENST00000586519 ENST00000590856 ENST00000586930 ENST00000591563 ENST00000591616
ENST00000586147 ENST00000587105 ENST00000587504 ENST00000592386 ENST00000590762
ENST00000587495 ENST00000585574 ENST00000586108 ENST00000588774
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for UNC13D
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNC13D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNC13D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNC13D |
Additional mRNA sequence: AJ578444.1 AK300316.1 AK301529.1 BC024740.2 BC067084.1 BC139835.1 14 DOTS entries: DT.99932871 DT.100029123 DT.95170059 DT.95344172 DT.100029122 DT.100029124 DT.443862 DT.95079421 DT.99983940 DT.100798436 DT.120969949 DT.411491 DT.91717394 DT.91668336 24/204 AceView cDNA sequences (see all 204): BQ223067 BU179669 AJ578444 NM_199242 AI961015 AW027302 AI814239 AI831754 BM850971 BF916818 AI699283 BM843786 BM818363 BQ953730 AI742099 BQ686867 AI524238 T83023 AW964054 BQ689368 BX389742 BM855779 BM768728 AI380578
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for UNC13D About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UNC13D
|
Expression
for UNC13D gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UNC13D expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GTGATGGGGG
About this image
See UNC13D Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UNC13D
SOURCE GeneReport for Unigene cluster: Hs.41045
UniProtKB/Swiss-Prot: UN13D_HUMAN, Q70J99Tissue specificity: Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and
placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic
T-lymphocytes (CTL) and mast cells
SABiosciences Custom PCR Arrays for UNC13D
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for UNC13D
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UNC13D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNC13D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNC13D | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC13D |
Orthologs
for UNC13D gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for UNC13D gene from 6/14 species (see all 14) About this table
ENSEMBL Gene Tree for UNC13D (if available)
TreeFam Gene Tree for UNC13D (if available) |
Paralogs
for UNC13D gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UNC13D gene
- BAIAP32
2 SIMAP similar genes for UNC13D using alignment to 8 protein entries: UN13D_HUMAN (see all proteins):BAIAP3 SYT5
UNC13D for paralogs About GeneDecksing
|
Genomic Variants
for UNC13D gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UNC13D (73823306 - 73840798 bp)
Structural Variations
Database of Genomic Variants (DGV) 8 variations for UNC13D: About this table
Human Gene Mutation Database (HGMD): UNC13D
Locus Specific Mutation Databases (LSDB): UNC13D
| | SABiosciences Cancer Mutation PCR Assays |
| | SeqTarget long-range PCR primers for resequencing UNC13D |
|
Disorders
/ Diseases
for UNC13D gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Novoseek, Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OMIM gene information: 608897
OMIM disorders: 608898
UniProtKB/Swiss-Prot: UN13D_HUMAN, Q70J99
Familial hemophagocytic lymphohistiocytosis 3 (FHL3) [MIM:608898]: A rare disorder characterized by
immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration
of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever,
hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and
hypotonia to seizures, cranial nerve deficits and ataxia. Note=The disease is caused by mutations affecting the
gene represented in this entry
12  diseases for UNC13D: About MalaCardshemophagocytic lymphohistiocytosis hemophagocytic lymphohistiocytosis, familial hemophagocytic lymphohistiocytosis, familial, 3 systemic onset juvenile idiopathic arthritis
griscelli syndrome type 2 griscelli syndrome chediak-higashi syndrome hydrops fetalis
hypotonia hypertriglyceridemia ataxia arthritis
2 diseases from the University of Copenhagen DISEASES database for UNC13D:Hemophagocytic lymphohistiocytosis Chediak-Higashi syndrome
UNC13D for disorders About GeneDecksing
3 Novoseek inferred disease relationships for UNC13D gene About this table
GeneTests: UNC13D
GeneReviews: UNC13D
Genetic Association Database (GAD): UNC13D
Human Genome Epidemiology (HuGE) Navigator: UNC13D (3 documents)
Export disorders for UNC13D gene to outside databases
|
Publications
for UNC13D gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UNC13D gene, integrated from 9 sources (see all 57):
(articles sorted by number of sources associating them with UNC13D) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms. (PubMed id 18759271)1, 4 Zhang K....Grom A.A. (2008)
- Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis. (PubMed id 18311812)1, 4 Donn R....Ramanan A.V. (2008)
- Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis. (PubMed id 18710388)1, 4 Horne A....Henter J.I. (2008)
- Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. (PubMed id 17237785)1, 2 Menager M.M.... de Saint Basile G. (2007)
- Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. (PubMed id 15548590)1, 2 Neeft M.... van der Sluijs P. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). (PubMed id 14622600)1, 2 Feldmann J....de Saint Basile G. (2003)
- Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 2 Hattori A.... Ohara O. (2000)
- Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. (PubMed id 19704116)1, 9 Wood S.M....Bryceson Y.T. (2009)
|
External Searches for UNC13D gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UNC13D gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UNC13D gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UNC13D gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UNC13D | Pharmacogenomics, SNPs, Pathways | | UNC13Dbase | http://bioinf.uta.fi/UNC13Dbase/ | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/UNC13D |
|
| | |
About This Section
| Patent Information for UNC13D gene:
Search GeneIP for patents involving UNC13D
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UNC13D gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UNC13D | | | QIAGEN SeqTarget long-range PCR primers for resequencing UNC13D | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UNC13D | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UNC13D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UNC13D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UNC13D |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UNC13D |
|  |  |  |  | | | | ThermoFisher Antibody for UNC13D |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UNC13D |
| |  |  |  | | | | LSBio Antibodies in human, mouse, rat for UNC13D |
| |
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