Aliases for UNC13D Gene
Aliases for UNC13D Gene
External Ids for UNC13D Gene
- HGNC: 23147
- Entrez Gene: 201294
- Ensembl: ENSG00000092929
- OMIM: 608897
- UniProtKB: Q70J99
Previous GeneCards Identifiers for UNC13D Gene
- GC17M074420
- GC17M071334
- GC17M073823
- GC17M069249
Summaries for UNC13D Gene
-
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]
GeneCards Summary for UNC13D Gene
UNC13D (Unc-13 Homolog D) is a Protein Coding gene. Diseases associated with UNC13D include Hemophagocytic Lymphohistiocytosis, Familial, 3 and Hemophagocytic Lymphohistiocytosis. Among its related pathways are Immune System and Deregulation of Rab and Rab Effector Genes in Bladder Cancer. GO annotations related to this gene include Rab GTPase binding. An important paralog of this gene is BAIAP3.
UniProtKB/Swiss-Prot for UNC13D Gene
-
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UNC13D Gene
Genomics for UNC13D Gene
Regulatory Elements for UNC13D Gene
Enhancers for UNC13D Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around UNC13D on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for UNC13D Gene
- Chromosome:
- 17
- Start:
- 75,827,225 bp from pter
- End:
- 75,844,717 bp from pter
- Size:
- 17,493 bases
- Orientation:
- Minus strand
Genomic View for UNC13D Gene
Genes around UNC13D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by Ensembl
- 17q25.1 by Entrez Gene
- 17q25.3 by HGNC
UNC13D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for UNC13D Gene
Proteins for UNC13D Gene
-
Protein details for UNC13D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q70J99-UN13D_HUMAN
- Recommended name:
- Protein unc-13 homolog D
- Protein Accession:
- Q70J99
- B4DWG9
- Q9H7K5
Protein attributes for UNC13D Gene
- Size:
- 1090 amino acids
- Molecular mass:
- 123282 Da
- Quaternary structure:
-
- Interacts with DOC2A (By similarity). Interacts with RAB27A.
- SequenceCaution:
-
- Sequence=BAB15764.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for UNC13D Gene
Post-translational modifications for UNC13D Gene
Other Protein References for UNC13D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for UNC13D (UNC13D)
- Novus Biologicals Antibodies for UNC13D
- Invitrogen Antibodies for UNC13D
- antibodies-online Antibodies for UNC13D: See all 58
- GeneTex UNC13D antibody for UNC13D
-
St John's Laboratory Antibodies for UNC13D
-
Santa Cruz Biotechnology (SCBT) Antibodies for UNC13D
Protein Products
-
OriGene Purified Proteins for UNC13D
- Search Origene for MassSpec and Protein Over-expression Lysates for UNC13D
- Origene Custom Protein Services for UNC13D
- antibodies-online Proteins for UNC13D: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for UNC13D
Assay Products
No data available for DME Specific Peptides for UNC13D Gene
Domains & Families for UNC13D Gene
Gene Families for UNC13D Gene
- HGNC:
Protein Domains for UNC13D Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for UNC13D Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q70J99UniProtKB/Swiss-Prot:
UN13D_HUMAN :- The MHD1 and MHD2 domains mediate localization on recycling endosomes and lysosome.
- Belongs to the unc-13 family.
- Domain:
-
- The MHD1 and MHD2 domains mediate localization on recycling endosomes and lysosome.
- Contains 2 C2 domains.
- Contains 1 MHD1 (MUNC13 homology domain 1) domain.
- Contains 1 MHD2 (MUNC13 homology domain 2) domain.
- Family:
-
- Belongs to the unc-13 family.
Function for UNC13D Gene
Molecular function for UNC13D Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15548590 |
| GO:0017137 | Rab GTPase binding | IPI | 22899725 |
Phenotypes for UNC13D Gene
- MGI mutant phenotypes for UNC13D:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for UNC13D:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Mildly decreased CFP-tsO45G cell surface transport
- Dynamic nuclei (hole, folded or small irregular)
- Decreased number of cells in monopolar arrest with EMD534085 (a Kinesin-5 inhibitor)
- Increased G1 DNA content
- Decreased IL-8 secretion
Animal Models for UNC13D Gene
- MGI Knock Outs for UNC13D:
-
- Unc13d tm1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for UNC13D
-
-
ViGene Biosciences lentiviral particle packaged cDNA for UNC13D gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UNC13D gene
- Search ViGene Biosciences for UNC13D
CRISPR Products
-
OriGene CRISPR knockouts for UNC13D
- GenScript: Design CRISPR guide RNA sequences for UNC13D
miRNA for UNC13D Gene
- miRTarBase miRNAs that target UNC13D
-
- hsa-mir-335-5p (MIRT017327)
- hsa-mir-1-3p (MIRT023568)
- hsa-let-7b-5p (MIRT032278)
- hsa-mir-320a (MIRT044594)
- hsa-mir-3180-5p (MIRT650852)
- hsa-mir-7150 (MIRT650853)
- hsa-mir-6867-3p (MIRT650854)
- hsa-mir-211-5p (MIRT650855)
- hsa-mir-204-5p (MIRT650856)
- hsa-mir-6826-3p (MIRT650857)
- hsa-mir-4736 (MIRT650858)
- hsa-mir-4763-3p (MIRT650859)
- hsa-mir-1207-5p (MIRT650860)
- hsa-mir-4685-3p (MIRT650861)
- hsa-mir-4287 (MIRT650862)
- hsa-mir-7113-3p (MIRT650863)
- hsa-mir-4469 (MIRT650864)
- hsa-mir-6832-3p (MIRT650865)
- hsa-mir-6892-3p (MIRT650866)
- hsa-mir-6795-3p (MIRT650867)
- hsa-mir-6887-3p (MIRT650868)
- hsa-mir-665 (MIRT650869)
miRNA Products
- Search ViGene Biosciences for UNC13D
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for UNC13D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for UNC13D
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for UNC13D
Cell Line Products
-
Horizon Cell Lines for UNC13D
-
ViGene Biosciences adenoviral particle packaged cDNA for UNC13D gene
-
ViGene Biosciences lentiviral particle packaged cDNA for UNC13D gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UNC13D gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for UNC13D Gene
Localization for UNC13D Gene
Subcellular locations from UniProtKB/Swiss-Prot for UNC13D Gene
- Cytoplasm. Membrane; Peripheral membrane protein. Late endosome. Recycling endosome. Lysosome. Note=Colocalizes with cytotoxic granules at the plasma membrane. Localizes to endosomal exocytic vesicles.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| lysosome | 5 |
| endosome | 5 |
| extracellular | 4 |
| nucleus | 3 |
| endoplasmic reticulum | 3 |
| plasma membrane | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005764 | lysosome | IEA,IDA | 15548590 |
| GO:0005768 | endosome | IEA | -- |
| GO:0005770 | late endosome | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for UNC13D Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Immune System |
.61
|
|
| 2 | wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) | ||
| 3 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer | ||
Pathways by source for UNC13D Gene
1 BioSystems pathway for UNC13D Gene
2 Reactome pathways for UNC13D Gene
1 GeneGo (Thomson Reuters) pathway for UNC13D Gene
Interacting Proteins for UNC13D Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002432 | granuloma formation | IEA | -- |
| GO:0002467 | germinal center formation | IEA | -- |
| GO:0006887 | exocytosis | IEA | -- |
| GO:0006909 | phagocytosis | IEA | -- |
| GO:0043304 | regulation of mast cell degranulation | IMP | 15548590 |
No data available for SIGNOR curated interactions for UNC13D Gene
Transcripts for UNC13D Gene
mRNA/cDNA for UNC13D Gene
- (4) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (204) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for UNC13D Gene
CRISPR Products
-
OriGene CRISPR knockouts for UNC13D
- GenScript: Design CRISPR guide RNA sequences for UNC13D
miRNA Products
- Search ViGene Biosciences for UNC13D
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for UNC13D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for UNC13D
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for UNC13D
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - |
| ExUns: | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||
| SP2: |
Expression for UNC13D Gene
mRNA differential expression in normal tissues according to GTEx for UNC13D Gene
This gene is overexpressed in Whole Blood (x17.3) and Spleen (x4.4).
This gene is overexpressed in Peripheral blood mononuclear cells (35.9), Platelet (8.5), and Monocytes (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for UNC13D Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of UNC13D Gene:
UNC13DSOURCE GeneReport for Unigene cluster for UNC13D Gene:
Hs.41045mRNA Expression by UniProt/SwissProt for UNC13D Gene:
Q70J99-UN13D_HUMAN
Tissue specificity:
Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.
Primer Products
-
OriGene qPCR primer pairs for UNC13D
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for UNC13D Gene
Orthologs for UNC13D Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | UNC13D 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | UNC13D 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | UNC13D 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Unc13d 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Unc13d 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | UNC13D 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | UNC13D 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | UNC13D 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | unc13d 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | unc13d 34 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4543 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | unc-13-4A 35 |
|
ManyToMany | |
| CG34349 35 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | F54G2.1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for UNC13D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for UNC13D Gene
(2) SIMAP similar genes for UNC13D Gene using alignment to 8 proteins:
Variants for UNC13D Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121434352 | Pathogenic | 75,840,317(-) | GCTGC(C/G/T)GAGAG | reference, missense, stop-gained | |
| rs121434353 | Pathogenic | 75,836,662(-) | CCTGC(C/T)GACCT | reference, missense | |
| rs121434354 | Pathogenic | 75,831,153(-) | CTGCT(G/T)CCACG | reference, missense | |
| rs201908137 | Pathogenic | 75,840,506(+) | CCTCA(A/C)CTGCA | splice-donor-variant | |
| rs777759523 | Pathogenic | 75,836,338(+) | CCATA(C/T)CTGCA | splice-donor-variant |
Residual Variation Intolerance Score:
57.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.81;
83.43% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for UNC13D Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UNC13D Gene
Disorders for UNC13D Gene
(9) MalaCards diseases for UNC13D Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hemophagocytic lymphohistiocytosis, familial, 3 |
|
|
| hemophagocytic lymphohistiocytosis |
|
|
| lymphatic system disease |
|
|
| hemophagocytic lymphohistiocytosis, familial, 1 |
|
|
| griscelli syndrome, type 2 |
|
Search UNC13D in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
UN13D_HUMAN- Familial hemophagocytic lymphohistiocytosis 3 (FHL3) [MIM:608898]: A rare disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits and ataxia. {ECO:0000269 PubMed:14622600}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for UNC13D
No data available for Genatlas for UNC13D Gene
Publications for UNC13D Gene
- UNC13D is the predominant causative gene with recurrent splicing mutations in Korean patients with familial hemophagocytic lymphohistiocytosis. (PMID: 20015888) Yoon H.S. … Seo J.J. (Haematologica 2010) 3 22 64
- Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. (PMID: 19704116) Wood S.M. … Bryceson Y.T. (Blood 2009) 3 22 64
- Spectrum, and clinical and functional implications of UNC13D mutations in familial haemophagocytic lymphohistiocytosis. (PMID: 17993578) Rudd E. … Henter J.I. (J. Med. Genet. 2008) 3 22 64
- Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis. (PMID: 18240215) Hazen M.M. … Binstadt B.A. (Arthritis Rheum. 2008) 3 22 64
- Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis. (PMID: 18311812) Donn R. … Ramanan A.V. (Arthritis Rheum. 2008) 3 46 64
Products for UNC13D Gene
- R&D Systems Antibodies for UNC13D (UNC13D)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for UNC13D
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for UNC13D
- Search Origene for MassSpec and Protein Over-expression Lysates for UNC13D
- Origene Custom Protein Services for UNC13D
- Origene mouse_rna, siRNA, rat_shrna, shRNA, and RNAi products in human, mouse, rat for UNC13D
- Browse OriGene Inhibitory RNA Products For UNC13D
- OriGene qPCR primer pairs for UNC13D
- OriGene CRISPR knockouts for UNC13D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For UNC13D
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for UNC13D
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- GenScript Custom overexpressing Cell Line Services for UNC13D
- GenScript: Design CRISPR guide RNA sequences for UNC13D
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- GenScript Custom Peptide Services for UNC13D
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for UNC13D
- Novus Biologicals proteins and lysates for UNC13D
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for UNC13D: See all 58
- Search antibodies-online for kits
- antibodies-online Proteins for UNC13D: See all 3
- Search antibodies-online for peptides
- GeneTex UNC13D antibody for UNC13D
- Search GeneTex for Proteins for UNC13D
- ViGene Biosciences adenoviral particle packaged cDNA for UNC13D gene
- ViGene Biosciences lentiviral particle packaged cDNA for UNC13D gene
- ViGene Biosciences ready-to-package AAV shRNAs for UNC13D gene
- Search ViGene Biosciences for UNC13D
- Santa Cruz Biotechnology (SCBT) Antibodies for UNC13D
- Search Santa Cruz Biotechnology (SCBT) for UNC13D siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for UNC13D CRISPR
- Horizon Cell Lines for UNC13D
- Cyagen custom Knockout/knockin (KOKI) mouse models for UNC13D
- VectorBuilder custom plasmid, inducible vectors for UNC13D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for UNC13D
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for UNC13D Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
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