Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UMOD Gene

protein-coding GIFtS: 59
GCID: GC16M020344

uromodulin

(Previous names: uromodulin (uromucoid, Tamm-Horsfall glycoprotein) )

Explore 51 diseases affiliated with
UMOD via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Uromodulin¹		HNFJ1² ⁵
Uromodulin (Uromucoid, Tamm-Horsfall Glycoprotein)¹ ²		MCKD2² ⁵
Tamm-Horsfall Urinary Glycoprotein² ³		HNFJ²
THP² ³		THGP²
ADMCKD2² ⁵		Tamm-Horsfall Glycoprotein²
FJHN² ⁵		Uromucoid¹

External Ids:	HGNC: 12559¹	Entrez Gene: 7369²	Ensembl: ENSG00000169344⁷	OMIM: 191845⁵	UniProtKB: P07911³

Export aliases for UMOD gene to outside databases

Previous GC identifers: GC16P019829 GC16M019774 GC16M020271 GC16M020310 GC16M020251 GC16M018883

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UMOD:

This gene encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic

cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal

cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal

fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic

bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney

disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by

juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for

this gene, the full-length natures of only two have been described to date. These two represent the major variants of

this gene and encode the same isoform. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: UROM_HUMAN, P07911

Function: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick

ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing

the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and

TNF. Facilitates neutrophil migration across renal epithelial

Function: Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may

contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract

infection and modulates formation of supersaturated salts and their crystals

Gene Wiki entry for UMOD (Tamm-Horsfall protein)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UMOD gene promoter:
AhR Nkx3-1 Nkx3-1 v4 Brachyury XBP-1 Nkx3-1 v1 Nkx3-1 v2 HFH-1 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UMOD promoter sequence

Search SABiosciences Chromatin IP Primers for UMOD

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UMOD

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.3 Ensembl cytogenetic band: 16p12.3 HGNC cytogenetic band: 16p12.3

UMOD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UMOD gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M020344: view genomic region (about GC identifiers)

Start:	20,344,373 bp from pter	End:	20,367,623 bp from pter
Size:	23,251 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UROM_HUMAN, P07911 (See protein sequence)

Recommended Name: Uromodulin precursor

Size: 640 amino acids; 69761 Da

Subcellular location: Apical cell membrane; Lipid-anchor, GPI-anchor. Basolateral cell membrane; Lipid-anchor,

GPI-anchor. Cell projection, cilium membrane. Note=Only a small fraction is sort to the basolateral pole of tubular

epithelial cells compared to apical localization. Secreted into urine after cleavage. Colocalized with NPHP1 and KIF3A

Subcellular location: Uromodulin, secreted form: Secreted

Miscellaneous: A specific, but as yet unidentified, protease(s) cleaves off and releases UMOD into urine

Secondary accessions: B3KP48 B3KRN9 Q540J6 Q6ZS84 Q8IYG0

Alternative splicing: 4 isoforms: P07911-1 P07911-2 P07911-3 P07911-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UMOD: NX_P07911

Post-translational modifications:

N-glycosylated. N-glycan heterogeneity at Asn-232: Hex7HexNAc6 (major) and dHex1Hex7HexNAc6 (minor); at Asn-322:

dHex1Hex6HexNAc5 (minor), dHex1Hex7HexNAc6 (major) and dHex1Hex8HexNAc7 (minor); at Asn-396: Hex6HexNAc5 (major),

dHex1Hex6HexNAc5 (minor) and Hex7HexNAc6 (minor)¹

Proteolytically cleaved at a conserved C-terminal proteolytic cleavage site to generate the secreted form found into

urine¹

View neXtProt modification sites for NX_P07911

UMOD Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001008390.1 NP_003352.2

ENSEMBL proteins:

ENSP00000379438 ENSP00000379442 ENSP00000460548 ENSP00000460374 ENSP00000458939

ENSP00000459738 ENSP00000460845 ENSP00000461641 ENSP00000459724 ENSP00000461120

ENSP00000458695 ENSP00000416346 ENSP00000306279 ENSP00000379446

Human Recombinant Protein Products:

	EMD Millipore Purified and/or Recombinant UMOD Protein
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: UMOD Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for UMOD
	GenScript Custom Purified and Recombinant Proteins Services for UMOD
	Novus Biologicals UMOD Protein Novus Biologicals UMOD Lysates
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for UMOD
	Uscn Proteins for UMOD

Gene Ontology (GO): 5/13 cellular component terms (GO ID links to tree view) (see all 13): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000922	spindle pole	IDA	--
GO:0005576	extracellular region	--	--
GO:0005615	extracellular space	IEA	--
GO:0005794	Golgi apparatus	IEA	--
GO:0016323	basolateral plasma membrane	IDA	7028707

UMOD for ontologies About GeneDecksing

UMOD Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of UMOD
	R&D Systems Antibodies for UMOD (Uromodulin)
	Browse OriGene Antibodies OriGene Custom Antibody Services for UMOD
	GenScript Custom Superior Antibodies Services for UMOD
	Novus Biologicals UMOD Antibodies
	Search for Antibodies for UMOD at Abcam
	Uscn Antibodies for UMOD
	Search ThermoFisher Antibodies for UMOD

Assay Products for UMOD:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for UMOD
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for UMOD

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UMOD for domains About GeneDecksing

5/10 InterPro domains/families (see all 10):

IPR017977 ZP_dom_CS

IPR001881 EGF-like_Ca-bd

IPR000742 EG-like_dom

IPR009030 Growth_fac_rcpt

IPR001507 ZP_dom

Graphical View of Domain Structure for InterPro Entry P07911

ProtoNet protein and cluster: P07911

3 Blocks protein families:

IPB000152 Aspartic acid and asparagine hydroxylation site

IPB001507 Endoglin/CD105 antigen

IPB001881 EGF-like calcium-binding

UniProtKB/Swiss-Prot: UROM_HUMAN, P07911

Domain: The ZP domain is involved in the polymerization of the protein to promote the formation of complex gel-like

structure

Similarity: Contains 3 EGF-like domains

Similarity: Contains 1 ZP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: UROM_HUMAN, P07911

Function: Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick

ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing

the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and

TNF. Facilitates neutrophil migration across renal epithelial

Function: Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may

contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract

infection and modulates formation of supersaturated salts and their crystals

Genatlas biochemistry entry for UMOD:

uromodulin,uromucoid,expressed in kidney,homolog to GP2

miRNA Products:		OriGene 3'-UTR Clone (see all 2): UMOD Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UMOD
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate UMOD:
		hsa-miR-107 hsa-miR-103a
		SwitchGear 3'UTR luciferase reporter plasmid: UMOD 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UMOD (see all 7) OriGene shRNA RFP: UMOD OriGene siRNA: UMOD
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UMOD

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for UMOD

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UMOD (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UMOD (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): UMOD (NM_001008389)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for UMOD
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UMOD

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for UMOD
		Search LifeMap BioReagents cell lines for UMOD

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UMOD

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	--	--

UMOD for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for UMOD:

Decreased viability with pacli

Increased gamma-H2AX phosphory

Animal Models:
Mouse knock-outs for UMOD: Umod^tm1Xrw Umod^tm1Kuma
8 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Umod):

adipose tissue	growth/size	hematopoietic system	homeostasis/metabolism	immune system
other	renal/urinary system	skeleton

UMOD for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Selected targets of HNF1

Selected targets of HNF1

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for UMOD

Selected targets of HNF1

UMOD for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for UMOD

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

4 Interacting proteins for UMOD (P07911³ ENSP00000306279⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LTA	P01374³, ENSP00000403495⁴	I2D: score=3 STRING: ENSP00000403495
MMP8	P22894³, ENSP00000236826⁴	I2D: score=1 STRING: ENSP00000236826
IL1B	P01584³	I2D: score=1
--	ENSP00000372793⁴	STRING: ENSP00000372793

About this table

Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006968	cellular defense response	TAS	2409603
GO:0007588	excretion	IEA	--
GO:0008285	negative regulation of cell proliferation	TAS	2409603
GO:0010033	response to organic substance	IEA	--
GO:0048878	chemical homeostasis	IEA	--

UMOD for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

UMOD for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UMOD
10/29 Novoseek chemical compound relationships for UMOD gene (see all 29) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
thps	90.1	8	17345077 (4), 7783702 (3)
tamm	85.4	8	12900848 (2), 12270772 (1), 17065110 (1), 7490460 (1) (see all 6)
calcium oxalate	82	55	7783702 (4), 10096372 (4), 12424489 (3), 15855216 (3) (see all 23)
uric acid	64.5	15	16861244 (4), 11007825 (1), 12629136 (1), 17629875 (1) (see all 10)
sialic acid	60.7	25	9352687 (4), 10460894 (3), 15637470 (2), 7664879 (1) (see all 13)
oxalate	50.4	3	15327412 (1), 11007825 (1), 17629875 (1)
creatinine	42.2	15	1488322 (1), 10572998 (1), 17616355 (1), 9650124 (1) (see all 10)
citrate	38.4	20	7771027 (4), 10096372 (3), 8285211 (2), 17629875 (2) (see all 9)
monosaccharide	37.8	3	10815984 (1), 10424459 (1)
slex	36.7	3	10770931 (3)

Search CenterWatch for drugs/clinical trials and news about UMOD / UROM

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UMOD gene (2 alternative transcripts):

NM_001008389.1 NM_003361.2

Unigene Cluster for UMOD:

Uromodulin

Hs.654425 [show with all ESTs]

Unigene Representative Sequence: AK091961

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000396134(uc002dhb.3) ENST00000396138(uc002dgz.3) ENST00000570689

ENST00000570331 ENST00000573567 ENST00000571174 ENST00000577168 ENST00000574195

ENST00000576688 ENST00000570757 ENST00000576546 ENST00000570972 ENST00000424589

ENST00000302509(uc002dha.3) ENST00000396142

miRNA Products:		OriGene 3'-UTR Clone (see all 2): UMOD Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UMOD
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate UMOD:
		hsa-miR-107 hsa-miR-103a
		SwitchGear 3'UTR luciferase reporter plasmid: UMOD 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UMOD (see all 7) OriGene shRNA RFP: UMOD OriGene siRNA: UMOD
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UMOD

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UMOD (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UMOD (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): UMOD (NM_001008389)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for UMOD
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UMOD

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UMOD Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat UMOD
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UMOD
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UMOD

Additional cDNA sequence:

AK055722.1 AK091961.1 AK096043.1 AK127643.1 AK127648.1 BC035975.1 M15881.1 M17778.1

24/37 DOTS entries (see all 37):

DT.120685796 DT.120685823 DT.95264795 DT.100020311 DT.107035 DT.120685818 DT.120685769 DT.120685856

DT.120685831 DT.120685825 DT.102827271 DT.120685783 DT.120685802 DT.101981138 DT.120685846 DT.100020313

DT.100754194 DT.120685844 DT.120685826 DT.70100028 DT.120685837 DT.120685810 DT.120685835 DT.120685843

24/103 AceView cDNA sequences (see all 103):

BE463493 AI934416 AI768450 M15881 BG428950 AI640530 AI733047 AI700894

BX109279 AI284347 BE501786 AW051962 AI625807 AI791538 AK096043 BG401615

BE466514 AI791536 BX089145 BG430266 AW006836 AI793058 AI948705 BC035975

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for UMOD (see all 13) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	·	6e	·	6f	·	6g	^	7	^	8	^	9	^	10	^
SP1:																									-
SP2:																					-		-		-						-		-		-		-		-		-		-
SP3:																					-		-		-
SP4:
SP5:															-

ExUns:	11	^	12	^	13	^	14	^	15	^	16
SP1:	-
SP2:	-
SP3:	-
SP4:
SP5:

ECgene alternative splicing isoforms for UMOD

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UMOD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTGTTCAG

About this image

UMOD expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Distal Tubule

Distal Tubule Cells

Selective marker (cell-identifying gene)

Kidney

Kidney

Kidney

Kidney

Kidney

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

Parietal epithelial cells (PEC) (Adult Stem / Progenitor Cell)

Epithelium, Kidney

Renal-like cells (Derivation of renal-...)

Parietal epithelial cells (PEC) (Adult Stem / Progenitor Cell)

Epithelium, Kidney

See UMOD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UMOD

SOURCE GeneReport for Unigene cluster: Hs.654425

UniProtKB/Swiss-Prot: UROM_HUMAN, P07911

Tissue specificity: Synthesized exclusively in the kidney. Expressed exclusively by epithelial cells of the thick

ascending limb of Henle's loop (TALH) and of distal convoluted tubule lumen. Most abundant protein in normal urine

SABiosciences Expression via Pathway-Focused PCR Array including UMOD:

Terminal Differentiation Markers in human mouse rat

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UMOD Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat UMOD
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UMOD
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UMOD

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UMOD

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for UMOD gene from 2/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	--	--	55(a)	possible ortholog	GL343621.1(80661-89493)
zebrafish (Danio rerio)	Actinopterygii	CABZ01078124.1⁶ BX284640.2⁶ (see all 3)	--	4(a) 39(a) (see all 3)	possible ortholog 1 ↔ many (see all 3)	3(4400696-4433577) 1(55879044-55879346)

ENSEMBL Gene Tree for UMOD (if available)
TreeFam Gene Tree for UMOD (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UMOD gene

UMODL1² GP2² OIT3²

11 SIMAP similar genes for UMOD using alignment to 11 protein entries: UROM_HUMAN (see all proteins):

GP2 DKFZp779K0533 UMODL1 NELL2 SNED1 FBLN2

PROS1 CD97 LTBP3 MATN2 FBLN5

UMOD for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs28934584^1,2	C	pathogenic	18896964(-)	`CGCCCG/TGTCTC`	4	G C	mis¹ ese³		2		NA	4
rs28934583^1,2	C	probable-pathogenic	18896622(-)	`AGACCT/CGCGTG`	4	/R /C	mis¹ ese³		2		NA	4
rs28934582^1,2	C	probable-pathogenic	18896828(-)	`GCACTG/ATGAGT`	4	/Y /C	mis¹		2		NA	4
rs113468667^1,2	C,	--	18881140(+)	`AAAAGG/AGAGAA`	2	--	ut3¹		2		CSA WA	120
rs111699931^1,2	C,	--	18881166(+)	`ACAAAG/ACATGA`	2	--	ut3¹		2		NA	122
rs113852396^1,2		--	18881202(+)	`TGGCCC/AGCATC`	2	--	ut3¹		1		CSA	2
rs77999388^1,2	F,	--	18881523(+)	`TCCTCC/TGGCAC`	2	--	int¹		1		WA	118
rs114985207^1,2	C,F,	--	18882666(+)	`GCACAC/ACCTGG`	2	--	int¹		1		WA	118
rs111484604^1,2	C,	--	18882815(+)	`AGATGG/TATCTT`	2	--	int¹		2		CSA WA	120
rs9935075^1,2	C,F,H,	--	18883180(+)	`GCATAT/CCCTTT`	2	--	int¹		8		NS EA CSA WA	523
rs111658337^1,2	C,	--	18883981(+)	`ACAAAC/TCTCCT`	2	--	int¹		0	--	--	--	--
rs11865824^1,2	C,F,H,	--	18884105(+)	`accacT/Gcctaa`	2	--	int¹		6		NS EA NA WA	540
rs4496152^1,2	H	--	18884284(-)	`TAGTAG/AATGTG`	2	--	int¹		4		NS EA	416
rs36002304^1,2	C,	--	18884290(+)	`TACTAC/TAAATA`	2	--	int¹		2		CSA WA	120
rs111266260^1,2		--	18884390(+)	`GTTACC/ATTCAT`	2	--	int¹		1		CSA	2
rs4508425^1,2	C,H	--	18884661(-)	`TTCCGA/GAGTGG`	4	R	syn¹ ese³		4		NS EA	416
rs74011921^1,2	C,F,	--	18885150(+)	`CTCTGG/CTAAAA`	2	--	int¹		3		WA CSA	122
rs72776658^1,2	C,F,	--	18885630(+)	`AAGTGC/TGTAGA`	2	--	int¹		1		NA	120
rs72776659^1,2	C,	--	18885689(+)	`AAACTG/CTCATC`	2	--	int¹		2		NA	122
rs77085263^1,2	F,	--	18885827(+)	`GTACCG/AAGAGC`	2	--	int¹		1		WA	118
rs56210020^1,2	C,	--	18885911(+)	`AACCCG/AAAATA`	2	--	int¹		2		WA	120
rs80150221^1,2	F,	--	18886444(+)	`TCCCTG/CCTGTA`	2	--	int¹		1		EA	120
rs111624876^1,2	C,	--	18887082(+)	`CGTCTG/AAGAAT`	2	--	int¹		1		NA	2
rs71384446^1,2	C,F,	--	18887094(+)	`GAAAAA/CCCCAG`	2	--	int¹		7		NA WA CSA	248
rs75864273^1,2	C,	--	18887110(+)	`TGAGCT/CAACCT`	2	--	int¹		2		WA	120
rs113923200^1,2		--	18888351(+)	`TCAAAC/TGACCA`	2	--	int¹		1		CSA	2
rs72776660^1,2	C,	--	18888564(+)	`AATGGC/TTTCAC`	2	--	int¹		2		NA	122
rs11642202^1,2	C,H	--	18888967(+)	`AAAAAG/AATGCA`	2	--	int¹ trp³		4		NS EA	412
rs9928757^1,2	C,F,H,	--	18889498(+)	`gctctG/Catttg`	2	--	int¹		19		NS EA NA CSA WA	2141
rs74011922^1,2	C,	--	18889648(+)	`CCTGTA/GGCTTT`	2	--	int¹		2		WA	120
rs9928936^1,2	C,F,A,H,	--	18889684(+)	`GACAGG/AAACAC`	2	--	int¹		18		NS EA NA WA CSA	1920
rs74839510^1,2	F,	--	18889706(+)	`CTTTGG/ATCTCA`	2	--	int¹		1		WA	118
rs200543642^1,2	C	--	18889844(-)	`GGCTGG/TTNNNN`	2	--	int¹		0	--	--	--	--
rs75459600^1,2	C,F,	--	18890005(+)	`TAACTC/TGAGAC`	2	--	int¹		1		WA	118
rs74826888^1,2	F,	--	18890070(+)	`GCATAC/TGCAGG`	2	--	int¹		1		WA	118
rs60136849^1,2	C,F,	--	18890450(+)	`AGCACT/CCTTCT`	2	--	int¹		8		NA WA CSA EA	368
rs80269832^1,2		--	18891108(+)	`AATAAA/TTAAAT`	2	--	int¹		0	--	--	--	--
rs34115067^1,2	C,	--	18891218(+)	`AAAAA-/ATAAAA`	2	--	int¹		1		CSA	2
rs74011924^1,2	C,	--	18891279(+)	`GGCACT/CCTGCC`	2	--	int¹		2		WA	120
rs78913673^1,2	C,	--	18891326(+)	`AGGAGC/TGTAAT`	2	--	int¹		0	--	--	--	--
rs34857077^1,2	C,F,	--	18892647(+)	`ATTAG-/AAAAAA`	2	--	int¹		2		NA CSA	4
rs201364679^1,2	C	--	18892647(-)	`TTTTTC/TCTAAT`	2	--	int¹		0	--	--	--	--
rs112396745^1,2		--	18892741(+)	`AGTTCC/TTTCAG`	2	--	int¹		1		CSA	2
rs34356953^1,2	C,F,	--	18892960(+)	`GACATG/TAATTA`	2	--	int¹		7		NA WA CSA	248
rs10656659^1,2	C,	--	18893286(+)	`ttctt-/TTTC tttct`	2	--	int¹ trp³		0	--	--	--	--
rs9940449^1,2	H	--	18893658(+)	`TTTGAG/TGAGGC`	2	--	int¹		4		NS EA	418
rs116825157^1,2	C,F,	--	18893699(+)	`ATTAAG/AGATAC`	2	--	int¹		1		WA	118
rs111765416^1,2	F,	--	18893824(+)	`GGAGAG/ACTATC`	2	--	int¹		2		CSA	4
rs75255729^1,2	F,	--	18893956(+)	`GTACTA/GTTATT`	2	--	int¹		1		WA	118
rs77225526^1,2	C,	--	18895005(+)	`TTTTGA/TGACGG`	2	--	int¹		2		WA	120
rs11643133^1,2	C,H,	--	18895026(+)	`ttcggA/C/Tgacaa`	2	--	int¹		2		NA WA	122
rs11643246^1,2	C,H	--	18895118(+)	`ctcccG/Aagtag`	2	--	int¹		1		NA	4
rs77810419^1,2		--	18895670(+)	`TGCCAA/GTTGTA`	2	--	int¹		1		WA	118
rs77171110^1,2		--	18895942(+)	`TCAGAA/GAGAAG`	2	--	int¹		1		EA	120
rs74936567^1,2	C,F,	--	18897425(+)	`GTCTTG/TCTCTG`	2	--	int¹		2		WA NA	238
rs111536805^1,2	C,	--	18897710(+)	`AACCTG/TTTGCC`	2	--	int¹		2		WA	120
rs74778184^1,2	F,	--	18897792(+)	`GTGTCG/ACCTCC`	2	--	int¹		1		WA	118
rs34882080^1,2	C,F,	--	18898097(+)	`CCACAA/GAATAT`	2	--	int¹		8		NA WA CSA EA	368
rs11865380^1,2	C,H	--	18898120(+)	`aGGACA/CCCGCA`	2	--	int¹		0	--	--	--	--
rs35650857^1,2	C,F,	--	18898147(+)	`CCCAAC/TGTACT`	2	--	int¹		8		NA WA CSA	250
rs112433356^1,2	C,	--	18898514(+)	`GTCTCA/GAGTGC`	2	--	int¹		0	--	--	--	--
rs111449051^1,2		--	18898919(+)	`TGTCAC/TTTATA`	2	--	int¹		1		CSA	2
rs117738531^1,2	C,F,	--	18898941(+)	`ATTGCA/GTAACA`	2	--	int¹		1		NA	120
rs74906285^1,2	F,	--	18899306(+)	`CTTGAG/AACGAG`	2	--	int¹		1		WA	118
rs77981947^1,2	C,F,	--	18899308(+)	`TGAGAC/TGNNNN`	2	--	int¹		1		NA	120
rs78052469^1,2	C,	--	18900101(+)	`GACAAT/CTGATA`	2	--	int¹		2		WA	120
rs78992074^1,2	F,	--	18900317(+)	`GATGCG/AACCTA`	2	--	int¹		1		WA	118
rs11642834^1,2	H	--	18901590(+)	`AGAGCC/GTGAGT`	2	--	us2k¹ tfbs³		4		NS EA	420
rs112100230^1,2	C,	--	18902088(+)	`CATAGC/TATTCC`	2	--	us2k¹		1		WA	2
rs8062123^1,2	C,F,A,H,	--	20343953(+)	`CCGCCG/TACTCG`	2	--	ds500¹		10		NA WA CSA EA	372
rs144579833^1,2		--	20343977(+)	`CTAGGA/GTTACA`	2	--	ds500¹		0	--	--	--	--
rs148466560^1,2		--	20343987(+)	`AGGTGC/TGAGCC`	2	--	ds500¹		0	--	--	--	--
rs181711435^1,2		--	20343988(+)	`GGTGCA/GAGCCA`	2	--	ds500¹		0	--	--	--	--
rs8060932^1,2	C,F,A,H,	--	20344077(+)	`AGACAG/AGAAAC`	2	--	ds500¹		16		NS EA NA WA CSA	793
rs185834985^1,2		--	20344148(+)	`ATAGTA/TGATGC`	2	--	ds500¹		0	--	--	--	--
rs35137457^1,2	C,	--	20344276(+)	`GGTTA-/TTTTTT`	2	--	ds500¹		0	--	--	--	--
rs58784147^1,2	C	--	20344279(+)	`TTTTT-/TCCCAC`	2	--	ds500¹		0	--	--	--	--
rs142615504^1,2		--	20344291(+)	`CCACCA/GTAGGA`	2	--	ds500¹		0	--	--	--	--
rs115984552^1,2	F,	--	20344392(+)	`CATTAT/ATTTGC`	2	--	ut3¹		1		WA	118
rs150543656^1,2		--	20344418(+)	`GATGGC/GGGCCT`	2	--	ut3¹		0	--	--	--	--
rs145165861^1,2	C,F,	--	20344643(+)	`ACTGAA/GAAGTC`	4	S F	mis¹		1		NA	4536
rs199562069^1,2		--	20344735(+)	`GTACTA/GCTGTA`	2	--	int¹		0	--	--	--	--
rs143236208^1,2		--	20345068(+)	`AATGCC/TCGGTT`	2	--	int¹		0	--	--	--	--
rs191030260^1,2		--	20345070(+)	`TGCCCA/GGTTAG`	2	--	int¹		0	--	--	--	--
rs181819946^1,2		--	20345172(+)	`CCACAC/TGGAGA`	2	--	int¹		0	--	--	--	--
rs146672582^1,2		--	20345216(+)	`CCGGGC/TGTGGT`	2	--	int¹		0	--	--	--	--
rs140210098^1,2		--	20345334(+)	`CTGGGC/TGACAG`	2	--	int¹		0	--	--	--	--
rs149853771^1,2		--	20345402(+)	`TCCTTA/GGATCC`	2	--	int¹		0	--	--	--	--
rs145860382^1,2		--	20345453(+)	`ATTTTC/TAGACA`	2	--	int¹		0	--	--	--	--
rs187087030^1,2		--	20345455(+)	`TTTTAA/GACAAT`	2	--	int¹		0	--	--	--	--
rs1123670^1,2	C,F,A,H,	--	20345615(+)	`TCAACA/GAATAT`	2	--	int¹		24		NS EA NA WA CSA	2558
rs191101580^1,2		--	20345714(+)	`TTCATA/GTCCTT`	2	--	int¹		0	--	--	--	--
rs182404898^1,2		--	20345844(+)	`TGTGGA/GTAAAC`	2	--	int¹		0	--	--	--	--
rs188264376^1,2		--	20345867(+)	`CCTACA/CTTCTC`	2	--	int¹		0	--	--	--	--
rs148992560^1,2		--	20345887(+)	`TCTGGA/GCATGC`	2	--	int¹		0	--	--	--	--
rs190223491^1,2		--	20345998(+)	`GTTGCC/GTCTTC`	2	--	int¹		0	--	--	--	--
rs116594609^1,2	F,	--	20346057(+)	`GAGGAG/ACAAAG`	2	--	int¹		1		WA	118
rs11365132^1,2	C	--	20346158(+)	`ACCTA-/TTTTTT`	2	--	int¹ trp³		0	--	--	--	--
rs55808501^1,2		--	20346256(+)	`TTCAAA/GCCATT`	2	--	int¹		1		CSA	1
rs138424073^1,2		--	20346278(+)	`GCCTCC/TCAAGT`	2	--	int¹		0	--	--	--	--
rs142448261^1,2		--	20346295(+)	`GAGGCA/GCGCGC`	2	--	int¹		0	--	--	--	--
rs146495867^1,2		--	20346395(+)	`CGCCCA/GCCTCA`	2	--	int¹		0	--	--	--	--
rs139047278^1,2	C,	--	20346867(+)	`GATCAA/GTGAAT`	2	--	int¹		0	--	--	--	--
rs141410325^1,2		--	20346976(+)	`CATGTC/TACTCC`	2	--	int¹		0	--	--	--	--
rs4635355^1,2	C,F,H,	--	20347156(-)	`TACAGC/TTTGGG`	2	--	int¹		11		NS EA NA WA	788
rs183170938^1,2		--	20347185(+)	`CAAAAG/TTATGA`	2	--	int¹		0	--	--	--	--
rs187459570^1,2		--	20347206(+)	`GAAAGA/GGAGCC`	2	--	int¹		0	--	--	--	--
rs192601473^1,2		--	20347229(+)	`CCCATC/GTTGGT`	2	--	int¹		0	--	--	--	--
rs185770631^1,2		--	20347320(+)	`AAAGAC/TGATAA`	2	--	int¹		0	--	--	--	--
rs138076215^1,2		--	20347795(+)	`TGTATA/GAATGG`	2	--	int¹		0	--	--	--	--
rs192734504^1,2		--	20347859(+)	`GCTCCC/TAGTTC`	2	--	int¹		0	--	--	--	--
rs200399798^1,2		--	20347973(+)	`CTTTCC/TGTGTG`	4	Q R	mis¹		0	--	--	--	--
rs184339980^1,2	C,	--	20348010(+)	`TTGATC/TTATGA`	4	N D	mis¹		0	--	--	--	--
rs111992415^1,2	C,F,	--	20348036(+)	`ATCTGG/ATCCCA`	4	/T /I	mis¹		2		CSA NA	4554
rs143641292^1,2	C,F	--	20348048(+)	`AGCAGG/TTCTAC`	4	N T	mis¹		2		NA EU	5863
rs146004778^1,2		--	20348137(+)	`CACAGA/GTGCCT`	2	--	int¹		0	--	--	--	--
rs115257363^1,2	F,	--	20348160(+)	`GGCAGA/TAGTTG`	2	--	int¹		1		WA	118
rs116189548^1,2	F,	--	20348221(+)	`TTAGAT/CAGATG`	2	--	int¹		1		WA	118
rs116674896^1,2	C,	--	20348575(+)	`CTTTGG/ATTACA`	2	--	int¹		2		WA EU	1369
rs113452476^1,2	C,	--	20348595(+)	`CTGGGG/AGAGGG`	2	--	int¹		1		CSA	2
rs199633513^1,2		--	20348692(+)	`CAAACC/TGGAAC`	4	Q R	mis¹		0	--	--	--	--
rs188709583^1,2	C,	--	20348705(+)	`CTGGAC/TGGAAA`	4	I V	mis¹		0	--	--	--	--
rs181145949^1,2		--	20348940(+)	`TGATCA/GCAGCC`	2	--	int¹		0	--	--	--	--
rs184442422^1,2		--	20349069(+)	`CAGAGC/GTGAAA`	2	--	int¹		0	--	--	--	--
rs117849751^1,2		--	20349109(+)	`CCAGCA/GATGAC`	2	--	int¹		1		NA	120
rs189031665^1,2		--	20349552(+)	`CAACTC/TCTGAA`	2	--	int¹		0	--	--	--	--
rs116884877^1,2	F,	--	20349594(+)	`GTGCTC/TAAGCC`	2	--	int¹		1		EA	120
rs146200256^1,2		--	20349652(+)	`GACTTA/GTCTCC`	2	--	int¹		0	--	--	--	--
rs181529209^1,2		--	20349711(+)	`CTCACC/TCCAGC`	2	--	int¹		0	--	--	--	--
rs148412868^1,2		--	20349718(+)	`CAGCTA/CCCACA`	2	--	int¹		0	--	--	--	--
rs142508284^1,2		--	20349797(+)	`TTTTCC/TGCAAT`	2	--	int¹		0	--	--	--	--
rs187437846^1,2		--	20350049(+)	`GACCTC/TGTGAT`	2	--	int¹		0	--	--	--	--
rs115879056^1,2	F,	--	20350075(+)	`TCCCTG/ACTATG`	2	--	int¹		1		WA	118
rs8044650^1,2	C,F,	--	20350163(+)	`TGCAAT/CCTCTG`	2	--	int¹		4		NA WA CSA	7
rs139401892^1,2		--	20350174(+)	`CCTCCA/TGGGTT`	2	--	int¹		0	--	--	--	--
rs150052437^1,2		--	20350227(+)	`CAGGCA/GCCCAC`	2	--	int¹		0	--	--	--	--
rs6497474^1,2	C,	--	20350242(+)	`ATGCCC/TGTCTA`	2	--	int¹		8		NA WA CSA	15
rs190187253^1,2		--	20350346(+)	`CCAAAG/TTGCTG`	2	--	int¹		0	--	--	--	--
rs181066099^1,2		--	20350372(+)	`GCCATC/TGTGCC`	2	--	int¹		0	--	--	--	--
rs146641336^1,2		--	20350468(+)	`AGAGAC/GATGAG`	2	--	int¹		0	--	--	--	--
rs147902589^1,2		--	20350529(+)	`AATCTA/CTGTGA`	2	--	int¹		0	--	--	--	--
rs185907304^1,2		--	20350583(+)	`TTTTTC/TTCTTT`	2	--	int¹		0	--	--	--	--
rs116040334^1,2	F,	--	20350612(+)	`TGAGCG/ATTTTC`	2	--	int¹		1		WA	118
rs190373935^1,2		--	20350617(+)	`GTTTTC/TCTGTG`	2	--	int¹		0	--	--	--	--
rs148936697^1,2		--	20350796(+)	`ACAAAA/CGAGTT`	2	--	int¹		0	--	--	--	--
rs182592200^1,2		--	20350905(+)	`ATCACA/TTTGGC`	2	--	int¹		0	--	--	--	--
rs185588862^1,2		--	20350928(+)	`ATATTC/TCCTTG`	2	--	int¹		0	--	--	--	--
rs8051744^1,2	C,H,	--	20351134(+)	`TTGTTC/TCTTCT`	2	--	int¹		17		NS EA NA WA CSA	790
rs74877674^1,2		--	20351206(+)	`ATGAAC/TGAGAA`	2	--	int¹		0	--	--	--	--
rs115581929^1,2	F,	--	20351207(+)	`TGAACG/AAGAAA`	2	--	int¹		1		WA	118
rs11859916^1,2	C,F,H,	--	20351231(+)	`TCATGG/ATAAGG`	2	--	int¹		24		NS EA NA WA CSA	2770
rs9923532^1,2	C,F,A,H,	--	20351596(+)	`GGCTAA/GAGCTG`	2	--	int¹		7		NS NA WA	368
rs115048026^1,2	F,	--	20351721(+)	`CGACCA/GAAAAA`	2	--	int¹		1		WA	118
rs10533543^1,2	C,	--	20351795(+)	`GTGTGTA/-TATAT`	2	--	int¹		1		NA	2
rs55906116^1,2	C,	--	20351815(+)	`ATATAA/TAATAC`	2	--	int¹		1		WA	2
rs201095057^1,2		--	20351815(+)	`ATATA-/TAATAC`	2	--	int¹		0	--	--	--	--
rs193084327^1,2		--	20351838(+)	`TTGCCA/GATACA`	2	--	int¹		0	--	--	--	--
rs7198000^1,2	C,F,H,	--	20351937(+)	`CACACG/AACCTG`	2	--	int¹		18		NS EA NA WA CSA	2330
rs182992435^1,2		--	20352089(+)	`AGGGGG/TTGGAT`	2	--	int¹		0	--	--	--	--
rs186584867^1,2		--	20352153(+)	`TCTACC/TAAAAA`	2	--	int¹		0	--	--	--	--
rs191176763^1,2		--	20352252(+)	`CGGAGG/TTTGCA`	2	--	int¹		0	--	--	--	--
rs148078324^1,2	C,	--	20352393(+)	`TCCCAA/TGTAGG`	2	--	int¹		0	--	--	--	--
rs184055420^1,2	C,	--	20352402(+)	`GGAACC/TTTTGC`	2	--	int¹		0	--	--	--	--
rs202057954^1,2		--	20352430(+)	`ATGAAC/GTACTT`	4	Y *	stg¹		0	--	--	--	--
rs200895986^1,2		--	20352490(+)	`AGCAGC/TGCAAA`	4	A	syn¹		0	--	--	--	--
rs188397613^1,2	C,	--	20352497(+)	`CAAATC/TGGGAC`	4	Q R	mis¹		0	--	--	--	--
rs141912637^1,2	C,F,	--	20352526(+)	`ATGGTG/ACCCAC`	4	/G	syn¹		1		NA	4552
rs141800038^1,2	C,F,	--	20352532(+)	`CCCACG/ATAGAG`	4	/Y	syn¹		2		NA EU	5873
rs143583842^1,2	C,F	--	20352584(+)	`GCTGCG/ATGTAG`	4	/T /M	mis¹		1		NA	4552
rs147222401^1,2	F	--	20352607(+)	`AAGAGC/TGCCAT`	4	A	syn¹		1		NA	4552
rs201761378^1,2	C,	--	20352614(+)	`CCATCC/TGCACG`	4	Q R	mis¹		0	--	--	--	--
rs139607138^1,2	C,F,	--	20352615(+)	`CATCCG/ACACGG`	4	/R /W	mis¹		2		NA EU	5875
rs55772253^1,2	C,F,	--	20352618(+)	`CCGCAC/AGGTGA`	4	/V /L	mis¹		2		NA EU	5873
rs138682701^1,2	C,	--	20352636(+)	`GGTCCC/TGCCCA`	4	R G	mis¹		0	--	--	--	--
rs111904030^1,2	C,F,	--	20352637(+)	`GTCCCG/CCCCAC`	4	/G	syn¹		2		CSA NA	4554
rs200545957^1,2		--	20352691(+)	`GACCGA/GGCTGA`	2	--	int¹		0	--	--	--	--
rs9646256^1,2	C,F,H,	--	20352756(+)	`CAGTTA/GTTTGC`	2	--	int¹		23		NS EA NA WA	2762
rs185145206^1,2		--	20352791(+)	`AACCCA/GCCAAC`	2	--	int¹		0	--	--	--	--
rs141733080^1,2		--	20352840(+)	`CTTGGG/TATCTA`	2	--	int¹		0	--	--	--	--
rs146226637^1,2		--	20352881(+)	`TTGGGA/GTGGGG`	2	--	int¹		0	--	--	--	--
rs190788083^1,2		--	20353008(+)	`CTACCC/TCTGTA`	2	--	int¹		0	--	--	--	--
rs139080345^1,2		--	20353022(+)	`TTCAAA/GATGGC`	2	--	int¹		0	--	--	--	--
rs35830321^1,2	C,	--	20353027(+)	`ATGGC-/AAAAAA`	2	--	int¹		0	--	--	--	--
rs149466530^1,2		--	20353058(+)	`ACCTGG/TATTCC`	2	--	int¹		0	--	--	--	--
rs143880155^1,2		--	20353073(+)	`TTGGTA/CTCAAT`	2	--	int¹		0	--	--	--	--
rs148604372^1,2		--	20353095(+)	`TAAAAA/GGTATT`	2	--	int¹		0	--	--	--	--
rs4780884^1,2	C,F,A,H,	--	20353127(+)	`CTTGCG/ATCCTG`	2	--	int¹		20		NS EA NA CSA WA	2344
rs182026809^1,2		--	20353145(+)	`TCGTGA/GTGTAC`	2	--	int¹		0	--	--	--	--
rs185418456^1,2		--	20353147(+)	`GTGATA/GTACTA`	2	--	int¹		0	--	--	--	--
rs114924681^1,2	F,	--	20353164(+)	`ATATCA/CGAAGA`	2	--	int¹		1		WA	118
rs188367320^1,2		--	20353282(+)	`AATAAA/GGCACA`	2	--	int¹		0	--	--	--	--
rs180741023^1,2		--	20353322(+)	`TTTTAC/TAGATG`	2	--	int¹		0	--	--	--	--
rs145665048^1,2		--	20353578(+)	`CTGAGA/GTGGGA`	2	--	int¹		0	--	--	--	--
rs147743088^1,2		--	20353635(+)	`TGCCAA/CTGCAC`	2	--	int¹		0	--	--	--	--
rs140968691^1,2		--	20353637(+)	`CCACTG/TCACTC`	2	--	int¹		0	--	--	--	--
rs144803314^1,2		--	20353674(+)	`GATTCA/GTAACA`	2	--	int¹		0	--	--	--	--
rs151283538^1,2		--	20353742(+)	`AGGCCA/GAGGAC`	2	--	int¹		0	--	--	--	--
rs140507502^1,2		--	20353777(+)	`GCTAGC/GCCAGG`	2	--	int¹		0	--	--	--	--
rs185741296^1,2		--	20353816(+)	`GCACTA/CTTCTT`	2	--	int¹		0	--	--	--	--
rs140335309^1,2	C,	--	20353827(+)	`CCTCC-/AAGTCA`	2	--	int¹		0	--	--	--	--
rs190992194^1,2		--	20353849(+)	`TCATCA/TGTGCC`	2	--	int¹		0	--	--	--	--
rs183820492^1,2		--	20353912(+)	`GCTTCA/GAAGGG`	2	--	int¹		0	--	--	--	--
rs144546203^1,2		--	20353915(+)	`TCGAA-/GGGAAG`	2	--	int¹		0	--	--	--	--
rs150422188^1,2		--	20354051(+)	`GAATAA/GTAATA`	2	--	int¹		0	--	--	--	--
rs145197770^1,2		--	20354099(+)	`TTTGAC/TGAGAT`	2	--	int¹		0	--	--	--	--
rs186684841^1,2		--	20354179(+)	`GGGCAC/TGGTGG`	2	--	int¹		0	--	--	--	--
rs116517097^1,2	F,	--	20354184(+)	`CGGTGG/ACTCAC`	2	--	int¹		1		WA	118
rs7498751^1,2	C,F,	--	20354280(+)	`AACCCT/CGTCTC`	2	--	int¹		3		NA	6
rs6497475^1,2	C,F,A,H,	--	20354282(+)	`CCCCGC/TCTCTA`	2	--	int¹		5		NA CSA	13
rs192410908^1,2		--	20354321(+)	`GTGGTA/GGGCAC`	2	--	int¹		0	--	--	--	--
rs138755971^1,2		--	20354384(+)	`GAGGCA/GGAGGT`	2	--	int¹		0	--	--	--	--
rs141775384^1,2		--	20354410(+)	`TCATGC/TCATTG`	2	--	int¹		0	--	--	--	--
rs183962941^1,2		--	20354447(+)	`ACTCCA/GTCTCA`	2	--	int¹		0	--	--	--	--
rs147846395^1,2		--	20354451(+)	`GTCTC-/AATA AATAA`	2	--	int¹		0	--	--	--	--
rs187598951^1,2		--	20354457(+)	`AATAAA/CTAAAT`	2	--	int¹		0	--	--	--	--
rs191307711^1,2		--	20354529(+)	`TGGCCC/TGTGAT`	2	--	int¹		0	--	--	--	--
rs182043143^1,2		--	20354722(+)	`AAATTC/TCTTTC`	2	--	int¹		0	--	--	--	--
rs201792712^1,2		--	20355309(+)	`TTAGAA/TCCATC`	2	--	int¹		0	--	--	--	--
rs201229685^1,2		--	20355386(+)	`TTTCAC/TGTCCA`	4	M V	mis¹		0	--	--	--	--
rs200394184^1,2		--	20355389(+)	`CATGTC/TCAGGG`	4	N D	mis¹		0	--	--	--	--
rs199565760^1,2		--	20355519(+)	`TGGAGC/GGGGGG`	2	--	int¹		0	--	--	--	--
rs187192153^1,2		--	20355634(+)	`AAAAAA/GCTGCC`	2	--	int¹		0	--	--	--	--
rs116287468^1,2	F,	--	20355646(+)	`GTGGCC/TGGGCG`	2	--	int¹		1		WA	118
rs118059635^1,2	F,	--	20355650(+)	`CCGGGC/TGCATT`	2	--	int¹		1		EA	120
rs8054296^1,2	C,F,	--	20355651(+)	`CGGGCG/ACATTA`	2	--	int¹		6		NA CSA WA EA	364
rs192687043^1,2		--	20355672(+)	`GTAATC/TCCAGC`	2	--	int¹		0	--	--	--	--
rs148024719^1,2		--	20355723(+)	`AGTTCA/GAGACC`	2	--	int¹		0	--	--	--	--
rs34262842^1,2	C,	--	20355811(+)	`TCCCAG/ACTACT`	2	--	int¹		1		NA	2
rs11310838^1,2	C,F	--	20355923(+)	`ATCTCA/-AAAAA`	2	--	int¹ trp³		2		NA	4
rs150523708^1,2		--	20355941(+)	`AAAATC/TCCACA`	2	--	int¹		0	--	--	--	--
rs11647727^1,2	C,F,H,	--	20356165(+)	`GACAGG/AGATTC`	2	--	int¹		27		NS EA WA NA CSA	2764
rs114514819^1,2	F,	--	20356276(+)	`CATATG/ACCAAG`	2	--	int¹		1		WA	118
rs73541299^1,2	C,	--	20356477(+)	`ATTACG/AGGTGC`	2	--	int¹		1		WA	2
rs185434506^1,2		--	20356615(+)	`ACAGGC/TGTGAG`	2	--	int¹		0	--	--	--	--
rs199835507^1,2		--	20356722(+)	`TTTTT-/TTTTC TTTCT`	2	--	int¹		0	--	--	--	--
rs28518775^1,2	C	--	20356748(+)	`TTTCTC/TTCTCT`	2	--	int¹		1		NA	2
rs28532040^1,2	C	--	20356750(+)	`TCTTTT/CTCTTT`	2	--	int¹		1		NA	2
rs140758974^1,2		--	20356762(+)	`TTTCT-/TTCTTCCT`	2	--	int¹		0	--	--	--	--
rs7203718^1,2	C	--	20356781(+)	`ctttcC/Tttcct`	2	--	int¹		1		NA	2
rs7196924^1,2	C	--	20356802(+)	`cttccC/Ttccct`	2	--	int¹		1		NA	2
rs189908977^1,2		--	20356806(+)	`CTTCCC/TTCCCT`	2	--	int¹		0	--	--	--	--
rs193056167^1,2		--	20356816(+)	`TCCCTC/TCCTCC`	2	--	int¹		0	--	--	--	--
rs7195581^1,2	C,	--	20356824(+)	`tccctC/Tccttc`	2	--	int¹		0	--	--	--	--
rs184978356^1,2		--	20356828(+)	`TCCCTC/TCCTTC`	2	--	int¹		0	--	--	--	--
rs189308784^1,2		--	20356832(+)	`TTCCTC/TCCTTC`	2	--	int¹		0	--	--	--	--
rs180894934^1,2		--	20356938(+)	`TCCTCC/TGGTAA`	2	--	int¹		0	--	--	--	--
rs183747797^1,2		--	20356943(+)	`TGGTAA/CTGAGG`	2	--	int¹		0	--	--	--	--
rs144892347^1,2		--	20357138(+)	`CCCTAC/TTATGG`	2	--	int¹		0	--	--	--	--
rs12934320^1,2	C,F,	--	20357255(+)	`cacttC/Taacac`	2	--	int¹		9		NA WA CSA	252
rs148548318^1,2		--	20357261(+)	`AACACA/GTTAAC`	2	--	int¹		0	--	--	--	--
rs12934455^1,2	C,F,	--	20357281(+)	`cctctC/Taatac`	2	--	int¹		5		NA	128
rs142877399^1,2		--	20357353(+)	`GGCTAA/CATAAC`	2	--	int¹		0	--	--	--	--
rs4506906^1,2	C,F,A,H,	--	20357398(-)	`TCAAGC/TTTCAG`	2	--	int¹		22		NS EA NA CSA WA	2339
rs189979715^1,2	C,	--	20357444(+)	`AGGACA/GTACCG`	2	--	int¹		0	--	--	--	--
rs201765927^1,2		--	20357468(+)	`ACAGGA/GGCCAT`	4	P S	mis¹		0	--	--	--	--
rs200414962^1,2	C,	--	20357477(+)	`ATCCCG/AGGCTG`	4	/R /W	mis¹		1		EU	1285
rs181197211^1,2	C,	--	20357482(+)	`GGGCTA/GGGGTC`	4	P L	mis¹		0	--	--	--	--
rs146885508^1,2	C,F,	--	20357484(+)	`GCTGGG/AGTCAC`	4	/T	syn¹		1		NA	4508
rs201738891^1,2		--	20357499(+)	`GACACC/GCAGTC`	4	C W	mis¹		0	--	--	--	--
rs151061376^1,2	C,F,	--	20357506(+)	`AGTCCC/TGGTTG`	4	Q R	mis¹		1		NA	4510
rs199926047^1,2		--	20357538(+)	`CACCGA/GCTGTC`	4	S	syn¹		0	--	--	--	--
rs78613713^1,2	C,F,	--	20357568(+)	`TTGTCG/AAAGCC`	4	/F	syn¹		2		WA NA	4670
rs201798915^1,2		--	20357671(+)	`GTTAGC/GTGGGA`	2	--	int¹		0	--	--	--	--
rs200760593^1,2		--	20357684(+)	`GAGGAC/TGTGTG`	2	--	int¹		0	--	--	--	--
rs186392255^1,2	C,	--	20357701(+)	`GCTTGA/GGGGCC`	2	--	int¹		0	--	--	--	--
rs191637934^1,2		--	20357958(+)	`CGTTTA/TAAAAA`	2	--	int¹		0	--	--	--	--
rs143561113^1,2		--	20357977(+)	`GCTAGA/CTGCGG`	2	--	int¹		0	--	--	--	--
rs181384140^1,2		--	20358048(+)	`CAGAGG/TTCAAT`	2	--	int¹		0	--	--	--	--
rs115612278^1,2	F,	--	20358079(+)	`AATACG/ACATCT`	2	--	int¹		1		WA	118
rs114112267^1,2	F,	--	20358082(+)	`ACGCAT/CCTCCC`	2	--	int¹		2		WA NA	238
rs115015222^1,2	F,	--	20358178(+)	`TAGAAC/TGTGAA`	2	--	int¹		1		WA	118
rs147502738^1,2	C,	--	20358206(+)	`AAGAG-/AGA AAGAAAGAAA`	2	--	int¹		0	--	--	--	--
rs149973371^1,2	C,	--	20358206(+)	`AAGAG-/AGAAAGA AAGAAAGAAAGAAA`	2	--	int¹		0	--	--	--	--
rs9928003^1,2	C,F,H,	--	20358248(+)	`AAGCAA/CGCTGc`	2	--	int¹		11		EA NS NA WA CSA	536
rs186258482^1,2		--	20358258(+)	`CAATTA/TCTTTC`	2	--	int¹		0	--	--	--	--
rs71377646^1,2	C,	--	20358346(+)	`CTCTCT/-TTTTT`	2	--	int¹		1		NA	2
rs146765952^1,2		--	20358375(+)	`CTCTTC/TGGCGA`	2	--	int¹		0	--	--	--	--
rs7203451^1,2	C,F,A,H,	--	20358376(+)	`TCTTCG/AGCGAC`	2	--	int¹		10		NA WA CSA EA	373
rs114333799^1,2	F,	--	20358404(+)	`CAGAGG/ATGCCA`	2	--	int¹		1		WA	118
rs58768874^1,2		--	20358525(+)	`TTTTTA/TGTAGA`	2	--	int¹		0	--	--	--	--
rs190867675^1,2		--	20358627(+)	`GGCATA/GAGCCA`	2	--	int¹		0	--	--	--	--
rs7204210^1,2	C,F,A,H,	--	20358684(+)	`GGGCTC/GAGAGT`	2	--	int¹		13		NA WA CSA EA	378
rs182342188^1,2		--	20358827(+)	`ACCTTC/TTTTTC`	2	--	int¹		0	--	--	--	--
rs28640218^1,2	C,F,	--	20359267(+)	`ACGTGG/TGTGCC`	2	--	int¹		11		NA WA CSA EA	374
rs74657669^1,2	C,	--	20359503(+)	`GCAGTG/AACAGG`	2	--	int¹		2		CSA WA	120
rs200571853^1,2		--	20359517(+)	`CTCAAA/CAACCC`	2	--	int¹		0	--	--	--	--
rs28544423^1,2	C,F,	--	20359633(+)	`CACGTC/TCCCTC`	4	G	syn¹ ese³		10		NA WA CSA EU	6124
rs149074866^1,2	C,	--	20359682(+)	`ACAATA/CAATAA`	2	--	int¹		0	--	--	--	--
rs80142672^1,2	C,	--	20359723(+)	`CCAGGC/TCTGGG`	2	--	int¹		3		CSA WA EA	240
rs78691203^1,2	C,F,	--	20359783(+)	`CACTCG/AGGGGG`	4	/P	syn¹		3		WA NA EU	4727
rs141383844^1,2	C	--	20359807(+)	`TAGACG/TTAGTA`	4	* Y	stg¹		1		NA	3326
rs13335818^1,2	C,F,H,	--	20359831(+)	`GCCTTC/TACCTG`	4	V	syn¹		23		NS EA NA CSA WA EU	5895
rs187555378^1,2	C,	--	20360085(+)	`GTCCAC/GGGTGC`	4	L V	mis¹		0	--	--	--	--
rs7193058^1,2	C,F,A,	--	20360101(+)	`GCCTGA/GCACGG`	4	C	syn¹ ese³		10		NA WA CSA EA	374
rs143965681^1,2	C,F,	--	20360290(+)	`GCGCAC/TTCATC`	4	E	syn¹		1		NA	3262
rs77875418^1,2	C,F,	--	20360359(+)	`AAGGAG/ACCTGG`	4	/G	syn¹		3		WA EA NA	4348
rs143248111^1,2	C	--	20360439(+)	`GCAGGT/GCAGGC`	4	/T /P	mis¹		1		NA	4472
rs146858440^1,2	F	--	20360485(+)	`GTAACG/AGCCTC`	4	/A	syn¹		1		NA	4138
rs111483946^1,2	C,	--	20360555(+)	`CCCAGC/TTTCAG`	2	--	int¹		1		CSA	2
rs201509608^1,2		--	20360577(+)	`CTGGGC/TCCATG`	2	--	int¹		0	--	--	--	--
rs183102463^1,2		--	20360649(+)	`AGAGGG/TCTCCC`	2	--	int¹		0	--	--	--	--
rs148214499^1,2		--	20360689(+)	`AAACTC/TCTCTG`	2	--	int¹		0	--	--	--	--
rs188132479^1,2		--	20360770(+)	`GAGAGA/GGGTCT`	2	--	int¹		0	--	--	--	--
rs192923680^1,2		--	20360797(+)	`CTGGAC/GTGCAG`	2	--	int¹		0	--	--	--	--
rs184360172^1,2		--	20360840(+)	`TCCTGC/GGTTCA`	2	--	int¹		0	--	--	--	--
rs116892778^1,2	F,	--	20360907(+)	`AGTTGG/TGACCA`	2	--	int¹		1		NA	120
rs142717731^1,2		--	20360919(+)	`AGGCAC/TGTGCA`	2	--	int¹		0	--	--	--	--
rs188077475^1,2		--	20360934(+)	`CGCCCA/GGCTCC`	2	--	int¹		0	--	--	--	--
rs71377647^1,2	C,F,	--	20360993(+)	`AATAGCCACA TTC/-CCACA`	2	--	int¹		2		NA CSA	4
rs147356761^1,2		--	20361048(+)	`ACGGTA/GAACCT`	2	--	int¹		0	--	--	--	--
rs12599312^1,2	C,F,H,	--	20361059(+)	`GTTGCC/TCCTCC`	2	--	int¹ trp³		6		NS EA NA	544
rs111285796¹

Advanced Search

Export list of displayed genes

UMOD Gene

uromodulin

Aliases
for UMOD gene

Summaries
for UMOD gene

Genomic Views
for UMOD gene

Proteins
for UMOD gene

Protein Domains /
Families
for UMOD gene

Function
for UMOD gene

Pathways & Interactions
for UMOD gene

Drugs & Compounds
for UMOD gene

Transcripts
for UMOD gene

Expression
for UMOD gene

Orthologs
for UMOD gene

Paralogs
for UMOD gene

Genomic Variants
for UMOD gene

Advanced Search

Export list of displayed genes

UMOD Gene

uromodulin

Aliasesfor UMOD gene

Summariesfor UMOD gene

Genomic Viewsfor UMOD gene

Proteinsfor UMOD gene

Protein Domains /Familiesfor UMOD gene

Functionfor UMOD gene

Pathways & Interactionsfor UMOD gene

Drugs & Compoundsfor UMOD gene

Transcriptsfor UMOD gene

Expression for UMOD gene

Orthologsfor UMOD gene

Paralogsfor UMOD gene

Genomic Variantsfor UMOD gene

Aliases
for UMOD gene

Summaries
for UMOD gene

Genomic Views
for UMOD gene

Proteins
for UMOD gene

Protein Domains /
Families
for UMOD gene

Function
for UMOD gene

Pathways & Interactions
for UMOD gene

Drugs & Compounds
for UMOD gene

Transcripts
for UMOD gene

Expression
for UMOD gene

Orthologs
for UMOD gene

Paralogs
for UMOD gene

Genomic Variants
for UMOD gene